Quality Of Life Measurement In Neurodegenerative And Related Conditions

Author : Crispin Jenkinson,Michele Peters,Mark B. Bromberg
Publisher : Cambridge University Press
Page : 207 pages
File Size : 53,8 Mb
Release : 2011-02-03
Category : Medical
ISBN : 9781139491341

Get Book

Quality of Life Measurement in Neurodegenerative and Related Conditions by Crispin Jenkinson,Michele Peters,Mark B. Bromberg Pdf

Patient reported outcome measures are central to the evaluation of medical care and treatment regimes. Such measures depart from traditional clinical assessments as they are based on issues known to be of importance to patients. This book outlines the development and application of a variety of such measures in a wide range of neurological conditions. Introductory chapters outline issues in the application and validation of quality-of-life measures in neurology. Subsequent chapters survey the most widely used quality-of-life instruments in Parkinson's disease, motor neurone disease, multiple sclerosis, multiple system atrophy, progressive supranuclear palsy, and Alzheimer's/dementia. A chapter on cerebral palsy deals with the particular challenges to developing outcome measures for children. The book also addresses issues relating to the translation of measures for use in cross-cultural studies, handling missing data, carer experiences of long-term conditions, and methodological challenges. Essential reading for clinicians and researchers working in the field of neurology.

Author : Charles Richard Boddington Joyce,Hannah M. McGee,Ciaran A. O'Boyle
Publisher : Taylor & Francis
Page : 258 pages
File Size : 47,7 Mb
Release : 1999
Category : Education
ISBN : 905702425X

Get Book

Individual Quality of Life by Charles Richard Boddington Joyce,Hannah M. McGee,Ciaran A. O'Boyle Pdf

The rubric "Quality of Life" first came to the explicit attention of the medical profession a little over thirty years ago. Despite the undoubted fact that each one of us has his or her own Quality of Life, be it good or bad, there is still no general agreement about its definition, or the manner in which it should be evaluated. Although much has been written about quality of life, this work has been largely concerned with population-based studies, especially in health policy & health economics. The importance of individual quality of life has been neglected, in part because of a failure to define quality of life itself with sufficient care, in part perhaps because of a belief that it is impossible to develop a meaningful method of measuring individual variables. It is a fundamental belief of the editors of this book that the primary focus of quality of life is & must continue to be the individual, who alone can define it & assess its changing personal significances. The individual perspective is of vital importance not only to patients but to their doctors too, & is more & more frequently proposed as the most meaningful measure of outcome in clinical research, especially in non-remitting or chronic conditions. Workers who wish to consider wider aspects of influences on the illnesses suffered by individuals & the health care that they receive will find much to stimulate them in the methods of documentation proposed in this book. Those mainly concerned with population samples rather than individuals may also find the sensitive methods of investigation proposed here not only to be applicable to their own areas of interest, but also rewarding in perhaps unexpected ways.

Author : Crispin Jenkinson,Ray Fitzpatrick,Damian Jenkinson
Publisher : CRC Press
Page : 224 pages
File Size : 52,9 Mb
Release : 2020-01-31
Category : Medical
ISBN : 9781315348308

Get Book

Health Status Measurement in Neurological Disorders by Crispin Jenkinson,Ray Fitzpatrick,Damian Jenkinson Pdf

The use of home detoxification enables health care workers to avoid episodes of in-patient care, with its inherent high costs and secondary problems of label attachment and possible stigmatization. Patients, their carers (professional, voluntary and domestic), families and friends all involved in this 'at-home' process, thereby leading to empowerment and increased compliance. This book provides practical advice and guidance. If all the procedures here are followed, the care worker of whatever discipline is unlikely to encounter major difficulties. Alcohol Home Detoxification and Assessment provides the kind of model increasingly required for the move towards community care of people with a whole range of conditions, and will enable professionals to organize the process with confidence.

Author : Joyce
Publisher : Psychology Press
Page : 247 pages
File Size : 46,6 Mb
Release : 2013-01-11
Category : Psychology
ISBN : 9781135852160

Get Book

Individual Quality of Life by Joyce Pdf

The rubric "Quality of Life" first came to the explicit attention of the medical profession a little over thirty years ago. Despite the undoubted fact that each one of us has his or her own Quality of Life, be it good or bad, there is still no general agreement about its definition, or the manner in which it should be evaluated. Although much has been written about quality of life, this work has been largely concerned with population-based studies, especially in health policy and health economics. The importance of "individual" quality of life has been neglected, in part because of a failure to define quality of life itself with sufficient care, in part perhaps because of a belief that it is impossible to develop a meaningful method of measuring individual variables. The editors of this book believe that the primary focus of quality of life is and must continue to be the individual, who alone can define it and assess its changing personal significance. The challenge of presenting this belief

Author : Jagan A Pillai PhD
Publisher : Oxford University Press
Page : 304 pages
File Size : 43,6 Mb
Release : 2016-10-17
Category : Medical
ISBN : 9780190233587

Get Book

Neurodegenerative Diseases by Jagan A Pillai PhD Pdf

As the global population ages the impact of neurodegenerative diseases like Alzheimer's disease and Parkinson's disease are significant forces in shaping human health and quality of life in the 21st century. Insights into understanding these diseases, and knowing how to treat them are major frontiers of scientific research. Neurodegenerative Diseases: Unifying Principles is the result of a conceptual revolution over the last decade in our understanding of neurodegenerative diseases as sharing unifying features. There is an increasing appreciation of the common biological and pathological features across seemingly varied neurodegenerative diseases that entail protein misfolding dysfunction and its consequences over time. Providing an overview of this conceptual change is the main theme for the book. Conventional approach emphasize the differences among neurodegenerative disorders, here Drs. Cummings and Pillai compile the increasingly compelling evidence that these disorders share many features and that insights in one may be rapidly translated into advances in another. The goal is to accelerate understanding by showing linkages among biological, pathological, can clinical aspects of this class of diseases. This collection of 19, inter-related chapters, articulates and broadens our view of the unifying features that initiate and drive disease progression across a variety of neurodegenerative diseases over time. This book will serve as an outstanding sourcebook of insights from experts that have played key roles in this story.

Author : Ivan Barofsky
Publisher : Springer Science & Business Media
Page : 496 pages
File Size : 46,9 Mb
Release : 2011-10-02
Category : Medical
ISBN : 1441998195

Get Book

Quality by Ivan Barofsky Pdf

Quality, as exemplified by Quality-of-life (QoL) assessment, is frequently discussed among health care professionals and often invoked as a goal for improvement, but somehow rarely defined, even as it is regularly assessed. It is understood that some medical patients have a better QoL than others, but should the QoL achieved be compared to an ideal state, or is it too personal and subjective to gauge? Can a better understanding of the concept help health care systems deliver services more effectively? Is QoL worth measuring at all? Integrating concepts from psychology, philosophy, neurocognition, and linguistics, this book attempts to answer these complex questions. It also breaks down the cognitive-linguistic components that comprise the judgment of quality, including description, evaluation, and valuations, and applies them to issues specific to individuals with chronic medical illness. In this context, quality/QoL assessment becomes an essential contributor to ethical practice, a critical step towards improving the nature of social interactions. The author considers linear, non-linear, and complexity-based models in analyzing key methodology and content issues in health-related QoL assessment. This book is certain to stimulate debate in the research and scientific communities. Its forward-looking perspective takes great strides toward promoting a common cognitive-linguistic model of how the judgment of quality occurs, thereby contributing important conceptual and empirical tools to its varied applications, including QoL assessment.

Author : Silvia Mandel
Publisher : Springer Science & Business Media
Page : 402 pages
File Size : 46,5 Mb
Release : 2013-03-12
Category : Medical
ISBN : 9789400758667

Get Book

Neurodegenerative Diseases: Integrative PPPM Approach as the Medicine of the Future by Silvia Mandel Pdf

This book will compile a collection of chapters dedicated to varied aspects of PPPM in neuropsychiatric and neurodegenerative diseases. Among the topics to be covered are: Recent advances in ALS research News about Clinical aspects and advanced therapy approaches in personalized treatment of ALS Schizophrenia: New treatments and clinical aspects Predictive, Preventive and Personalised Medicine in aging macular degeneration Advances in Multiple Sclerosis Pharmacogenetics, Tailoring Treatment Efficacy, Safety and Regimen Selection Multiple sclerosis related biomarkers: perspectives for clinical application Preventive clinical trials in brain aging: new trends & the need of guidelines MCI_ clinical guidelines in early diagnosis of dementia Alzheimer's disease: diagnostics, prognostics and the road to prevention Biomarkers for early diagnosis of Parkinson's and Alzheimer's diseases Synucleinopathies, tauopathies, TDP-43 proteinopathies and amyloidosis PSP, MSA and other parkinsonisms

Author : Francesco Pagnini,Zachary Simmons
Publisher : Oxford University Press
Page : 300 pages
File Size : 43,8 Mb
Release : 2018-02-09
Category : Medical
ISBN : 9780191075131

Get Book

Amyotrophic Lateral Sclerosis by Francesco Pagnini,Zachary Simmons Pdf

Amyotrophic Lateral Sclerosis (ALS) is a devastating neurodegenerative disorder with a progressive and fatal course, with no known medical therapies that can reverse the disease or halt its progression. Palliative care is the mainstay of disease management, aimed at maximizing Quality Of Life (QOL) for the patient and caregiver. Clinicians caring for patients with ALS need to understand complex psychological issues in the patient and caregiver, including depression, anxiety, hopelessness, and wish for hastened death (physician-assisted suicide). They also need to confront the psychological implications of rapidly advancing genetic research, the impact of cognitive and behavioural dysfunction in a sizable minority of ALS patients, and caregiver burnout. Healthcare providers can optimize care by better understanding not only these factors, but by learning how to facilitate their management with problem-solving, coping techniques, and with psychologically-based approaches such as mindfulness and other non-pharmacological approaches aimed at maximizing QOL. Amyotrophic Lateral Sclerosis: Understanding and Optimizing Quality of Life and Psychological Well-Being provides a detailed review and evaluation of ALS, presented in a comprehensive and integrated fashion. The book achieves this through detailed and up-to-date information about the current state of knowledge in this field. It also offers new insights regarding future directions for research. This book will provide clinicians with a comprehensive description of the psychological aspects of ALS and their management, and incorporates chapters written by recognized scholars in their respective fields.

Author : Matthew Rizzo,Steven Anderson,Bernd Fritzsch
Publisher : John Wiley & Sons
Page : 807 pages
File Size : 49,8 Mb
Release : 2018-05-29
Category : Psychology
ISBN : 9781118771778

Get Book

The Wiley Handbook on the Aging Mind and Brain by Matthew Rizzo,Steven Anderson,Bernd Fritzsch Pdf

A thought-provoking treatise on understanding and treating the aging mind and brain This handbook recognizes the critical issues surrounding mind and brain health by tackling overarching and pragmatic needs so as to better understand these multifaceted issues. This includes summarizing and synthesizing critical evidence, approaches, and strategies from multidisciplinary research—all of which have advanced our understanding of the neural substrates of attention, perception, memory, language, decision-making, motor behavior, social cognition, emotion, and other mental functions. Written by a plethora of health experts from around the world, The Wiley Handbook on the Aging Mind and Brain offers in-depth contributions in 7 sections: Introduction; Methods of Assessment; Brain Functions and Behavior across the Lifespan; Cognition, Behavior and Disease; Optimizing Brain Function in Health and Disease; Forensics, Competence, Legal, Ethics and Policy Issues; and Conclusion and New Directions. Geared toward improving the recognition, diagnosis, and treatment of many brain-based disorders that occur in older adults and that cause disability and death Seeks to advance the care of patients who have perceptual, cognitive, language, memory, emotional, and many other behavioral symptoms associated with these disorders Addresses principles and practice relevant to challenges posed by the US National Academy of Sciences and National Institute of Aging (NIA) Presents materials at a scientific level that is appropriate for a wide variety of providers The Wiley Handbook on the Aging Mind and Brain is an important text for neurologists, psychiatrists, psychologists, physiatrists, geriatricians, nurses, pharmacists, social workers, and other primary caregivers who care for patients in routine and specialty practices as well as students, interns, residents, and fellows.

Author : David Morley,Xiaoming Li,Crispin Jenkinson
Publisher : CRC Press
Page : 277 pages
File Size : 43,6 Mb
Release : 2016-09-15
Category : Medical
ISBN : 9781315349688

Get Book

Children and Young People’s Response to Parental Illness by David Morley,Xiaoming Li,Crispin Jenkinson Pdf

Assessment of the impact of parental illness has gathered significant momentum over recent years. This book provides an up-to-date guide, for a variety of professionals, on how a range of conditions might impact upon children and young people. Each chapter provides an overview of current literature, an evaluation of relevant interventions, an ‘in practice’ section that provides guidance for readers in terms of best practice, and future research directions. Although the primary focus of the book is directed at children’s and young people’s response to their parent’s condition, the challenges of parenting are also frequently highlighted. Additionally, the text provides an overview of measurement issues when investigating children’s and young people’s response to parental illness.

Author : Veerle Baekelandt,Evy Lobbestael
Publisher : Academic Press
Page : 324 pages
File Size : 48,6 Mb
Release : 2017-03-31
Category : Medical
ISBN : 9780128052662

Get Book

Disease-Modifying Targets in Neurodegenerative Disorders by Veerle Baekelandt,Evy Lobbestael Pdf

Disease-Modifying Targets in Neurodegenerative Disorders: Paving the Way for Disease-Modifying Therapies examines specific neurodegenerative disorders in comprehensive chapters written by experts in the respective fields. Each chapter contains a summary of the disease management field, subsequently elaborating on the molecular mechanisms and promising new targets for disease-modifying therapies. This overview is ideal for neuroscientists, biomedical researchers, medical doctors, and caregivers, not only providing readers with a summary of the way patients are treated today, but also offering a glance at the future of neurodegenerative disorder treatment. Provides a comprehensive overview of how key proteins in neurodegenerative disorders can be used as targets to modify disease progress Summarizes how patients are treated today, providing a glance at future disease management Includes intelligible and informative information that is perfect for non-specialists, medical practitioners, and scientists Written and peer reviewed by outstanding scientists in their respective fields

Author : Orla Hardiman,Colin P. Doherty,Marwa Elamin,Peter Bede
Publisher : Springer
Page : 336 pages
File Size : 42,6 Mb
Release : 2016-02-26
Category : Medical
ISBN : 9783319233093

Get Book

Neurodegenerative Disorders by Orla Hardiman,Colin P. Doherty,Marwa Elamin,Peter Bede Pdf

This new edition provides an accessible guide to the commonest neurodegenerative diseases, outlining the main clinical features, treatment options and outcomes of the conditions most frequently encountered in clinical practice. Beginning with an overview of the general principles that underlie degeneration, and the contribution of established and new diagnostics techniques, the book goes on to describe the most common neurodegenerative conditions and, new for the second edition, also HIV dementia and multiple sclerosis. Final chapters cover important management issues including the use of palliative care strategies, biomarkers and neuropsychology. Written by experts in the field internationally Neurodegenerative Disorders, Second Edition is a practical guide for clinicians that will be indispensable for the management of these conditions.

Author : Pablo Martinez-Martin,Carmen Rodriguez-Blazquez,Maria João Forjaz,Kallol Ray Chaudhuri
Publisher : Springer
Page : 96 pages
File Size : 43,5 Mb
Release : 2014-10-16
Category : Medical
ISBN : 9781907673887

Get Book

Guide to Assessment Scales in Parkinson’s Disease by Pablo Martinez-Martin,Carmen Rodriguez-Blazquez,Maria João Forjaz,Kallol Ray Chaudhuri Pdf

This Guide assesses the key clinimetric attributes in the assessment of Parkinson's Disease (PD), with the intention to offer rapid and pragmatic information on the most relevant scales used in PD. Parkinson’s disease affects approximately 4 million people globally and is most commonly seen in people over the age of 50. The disease is a progressive disorder of the nervous system, and presents a number of movement and cognitive symptoms, thereby greatly affecting a patients quality of life. The use of scales for assessment in neurological disorders such as PD arises from the need to quantify disorders and states (such constructs as disability, symptoms, quality of life). Assessment scales are often categorised into two categories: generic (i.e. those scales usable in any health condition), and specific (i.e. scales developed for exclusive use in PD). They can have a variety of components: single-item and multi-item or composite scale; unidimensional and multidimensional; and as disease-centered and patient-centered measures. The creation and validation of scales is complex, with scales undergoing numerous studies to assess criteria such as acceptability, reliability, and responsiveness. In the process of validation of a scale the following attributes should be tested to ascertain whether a scale is an effective instrument of measurement.

Author : Elisabetta Vaudano,Jean Georges,Monica Ensini,Martin Hofmann-Apitius,Donald C. Lo
Publisher : Frontiers Media SA
Page : 123 pages
File Size : 47,7 Mb
Release : 2023-11-08
Category : Medical
ISBN : 9782832538708

Get Book

Impacts of Public-Private Collaborative Research on Alzheimer's Disease: The Case of the Innovative Medicines Initiative by Elisabetta Vaudano,Jean Georges,Monica Ensini,Martin Hofmann-Apitius,Donald C. Lo Pdf

Author : Anonim
Publisher : Elsevier
Page : 290 pages
File Size : 49,5 Mb
Release : 2023-02-14
Category : Medical
ISBN : 9780323900645

Get Book

Precision Medicine in Neurodegenerative Disorders by Anonim Pdf

Precision Medicine in Neurodegenerative Disorders, Part One, Volume 192 in the Handbook of Clinical Neurology deals with the "Why" in the approach to slow the progression of accelerated brain aging. This volume is intended to provide a scholarly background on the framework, basic science and conceptual pitfalls related to disease-modifying efforts in Parkinson's, Alzheimer's and other neurodegenerative disorders. Among topics covered are different models of precision medicine, the lumping-versus-splitting tension in biomarker development and therapeutics, and the rationale for replacing the convergence of the prevailing autopsy-based nosology of neurodegenerative diseases with the divergence of a systems biology approach to human diseases. Specific chapters are dedicated to the promise of genetic subtypes and the lessons in disease modification offered by the fields of oncology and cystic fibrosis that can be adapted to the field of neurodegeneration. Matching a biology-correcting therapy with those biologically suitable to benefit from such therapy represents the vision and mission of precision medicine, the highest level of personalized medicine. Summarizes theory and research on precision medicine in neurodegenerative disorders Covers basic biology, clinical trials and therapeutics Includes disease mechanisms, genetic subtypes, and more