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Radiation Biophysics (ionizing Radiations) by I︠U︡riĭ Borisovich Kudri︠a︡shov Pdf
The book is concerned with features analysis of radiation damage to living matter at different levels of its organisation, beginning from the molecular level. The general theory of the mechanisms of biological action of radiation based on four logically connected principles of radiation biology is presented for the first time. The book contains abundant material on primary and secondary processes of the response of living systems to radiation, the mechanisms of direct and indirect action of radiation through radiolysis of water and lipids; a detailed consideration of the theory of targets (DNA and biological membranes) and the problems of high- and low-dose irradiation in the context of present-day. The systemic response of the cell to irradiation (oxidative stress, endogenous background radioresistance, damage and repair of biological membranes and DNA, systemic protection against radiation) is approximated. Presentation of these important problems is preceded by an up-to-date evaluation of some aspects regarding dosimetry of ionising radiation.
This newly revised and updated edition of Radiation Biophysics provides an in-depth description of the physics and chemistry of radiation and its effects on biological systems. Coverage begins with fundamental concepts of the physics of radiation and radioactivity, then progresses through the chemistry and biology of the interaction of radiation with living systems. The Second Edition of this highly praised text includes major revisions which reflect the rapid advances in the field. New material covers recent developments in the fields of carcinogenesis, DNA repair, molecular genetics, and the molecular biology of oncogenes and tumor suppressor genes. The book also includes extensive discussion of the practical impact of radiation on everyday life. Covers the fundamentals of radiation physics in a manner that is understandable to students and professionals with a limited physics background Includes problem sets and exercises to aid both teachers and students Discusses radioactivity, internally deposited radionuclides, and dosimetry Analyzes the risks for occupational and non-occupational workers exposed to radiation sources
Committee on Health Effects of Exposure to Low Levels of Ionizing Radiations (Beir VII),Commission on Life Sciences,Division on Earth and Life Studies,National Research Council
Author : Committee on Health Effects of Exposure to Low Levels of Ionizing Radiations (Beir VII),Commission on Life Sciences,Division on Earth and Life Studies,National Research Council Publisher : National Academies Press Page : 73 pages File Size : 53,8 Mb Release : 1998-08-18 Category : Science ISBN : 9780309580526
Health Effects of Exposure to Low Levels of Ionizing Radiations by Committee on Health Effects of Exposure to Low Levels of Ionizing Radiations (Beir VII),Commission on Life Sciences,Division on Earth and Life Studies,National Research Council Pdf
The US Environmotection Agency Office of Radiation and Indoor Air asked the National Research Council to evaluate whether sufficient new data exist to warrant a reassessment of health risks reported in Health Effects of Exposure to Low Levels of Ionizing Radiations (BEIR V) in 1990. To respond to this request, the National Research Council assembled the Committee on Health Risks of Exposure to Low Levels of Ionizing Radiations. The work of the committee was conducted in what was called the BEIR VII phase-1 study. To assist the committee during its deliberations, various scientists were consulted for advice, and a workshop on the impact of biology on risk assessment was held in collaboration with the Department of Energy Office of Health and Environmental Research. The intent of the workshop was to address the implications of new understanding of the biologic basis of radiation injury and carcinogenesis for risk assessment.
Author : Gopal B. Saha Publisher : Springer Science & Business Media Page : 220 pages File Size : 42,6 Mb Release : 2013-03-09 Category : Medical ISBN : 9781475761849
Physics and Radiobiology of Nuclear Medicine by Gopal B. Saha Pdf
A basic knowledge of physics, instrumentation, and radiobiology is essential for nuclear physicians and technologists in the practice of nuclear medicine. The nuclear medicine specialty has matured over the past three decades to the extent that there is an increasing need for certification of physicians and technologists to practice nuclear medicine. Each year many medical residents take the American Board of Nuclear Medicine examination and the Ameri can Board of Radiology examination with special competency in Nuclear Radiology, and many technologists take the Registry examination in Nuclear Medicine. All these tests include a good portion of physics, instrumenta tion, and radiobiology in nuclear medicine. It is mandatory that radiology residents pass the physics section of the American Board of Radiology examination. This book is primarily addressed to this audience. In addition, anyone in terested in the basics of physics, instrumentation, and radiobiology in nuclear medicine should find this book useful.
Medical Effects of Ionizing Radiation by Fred A. Mettler,Arthur C. Upton Pdf
Basic radiation physics, chemistry, and biology -- Sources of radiation exposure -- Effects on genetic material -- Cancer induction and dose-response models -- Carcinogenesis of specific sites -- Deterministic effects of radiation -- Effects of radiation in combination with other agents -- Radiation exposure in utero -- Uranium, plutonium, and radium -- Attribution of radiation effects and probability of causation in a specific individual -- Perception of radiation and psychological risks -- Hormesis.
In this compilation, the authors examine the importance of ionizing radiations for thermoluminescence dosimetry that is the current area of research for medical and industrial purposes. Ionizing radiations are harmful to the human body, so, there is a need to measure small doses in the environment as well as very high doses at the time of accident like radiation leakage and for the treatment of cancer. Next, recent advances regarding effects on exposure of some foods to ionizing radiations are presented. The dosage required for complete sterilization may, at times, lead to undesirable changes in food flavours or may exceed the permitted levels. Combining irradiation with other treatments yields satisfactory results in these cases. Combined applications of ionizing radiation with heat, low temperature, high hydrostatic pressure, and modified atmospheres are also discussed. Later, new results concerning cell survival and genetic instability of wild-type and radiosensitive yeast cells of Saccharomyces cerevisiae surviving after irradiation with 60Co γ-rays, 239Pu α-particles and 254 nm UV light are presented. Survival was determined by cell ability to produce macrocolonies on a solid nutrient medium. The authors also review data on the radiation resistance of AlGaN/GaN and InAlN/GaN High Electron Mobility Transistors (HEMTs) as well as emerging Ga2O3 photodetectors and rectifiers to different types of ionizing radiation. Both of these wide bandgap semiconductor (nitride-based and gallium oxide-based) materials are much more radiation-hard than GaAs or Si and this is largely a result of their high bond strengths. By using the test system of blood lymphocytes of healthy individuals, the following paper presents the co-mutagenic (potentiating) effect of the drugs a calcium channel blocker verapamil and an antioxidant ascorbic acid-on the radiosensitivity of cells. It was found that when the lymphocytes are irradiated in a small dose (0.3 Gy), ascorbic acid (80.0 μg / blood) and verapamil (4.0 μg / ml blood) increase the frequency of chromosomal aberrations in comparison with the radiation effect by 75 and 62, 5% respectively. Afterwards, the experimental data of the effects of temperature, light intensity, background ionizing and non-ionizing radiation on physicochemical properties of water, water solution and cell function are presented. Considering the fact that the cell membrane permeability for water is more than 10 times higher than for inorganic ions, it is hypothesized that, upon the effect of chemical and physical factors, the changes of net water efflux through the membrane precede the activation of ionic fluxes in the membrane. Also in this compilation, a study is included which investigated the modifying effect of astaxanthin on radiation induced genome damages in cultivating human peripheral blood lymphocytes (PBL). The study indicated that astaxanthin in concentration of 20.0 �g/ml demonstrated evident radioprotective properties by reduction of the ChA level, decreasing of DNA damages and increasing of the apoptotic rate. In the last chapter, the authors present some works that study the causes of the high resistance of IRRB to ionizing radiation. Then we focus on presenting in silico approaches that use protein sequences of bacteria in order to predict if an unknown bacterium belongs to IRRB or ionizing-radiationsensitive bacteria (IRSB).
Ionising Radiation and Mankind by D.V. Gopinath,N. Ramamoorthy Pdf
This book provides a comprehensive account of the developments and current status in several fields of the application of radioactivity and ionising radiation. It covers such topics as radiation-based techniques, radiation’s applications in medicine, food and agriculture, its impact on industry, and its associated materials. The book will be of interest to a wide variety of readers including professionals in radiation medicine, industrial processes, food preservation, and agriculture.
