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Radiation Therapy in Hematologic Malignancies by Bouthaina Shbib Dabaja,Andrea K. Ng Pdf
This book is designed to assist practitioners in managing patients who present with difficult cases of the most common hematological malignancies. The scenarios covered are those that are likely to be encountered in patients with the various forms of Hodgkin’s lymphoma, non-Hodgkin’s lymphoma, and leukemia. In each of the three sections devoted to these malignancies, multiple cases are presented. The case discussions follow a standard format. A clinical description is followed by a pathological description documenting information relevant to diagnosis and by details of staging work-up, including images. The treatment options are then discussed at length, highlighting relevant literature for each option. Finally, the treatment delivered is identified and images of the planning technique/modality used are provided. This book will be an invaluable aid to decision making for radiation oncologists and will also be of interest for hematologists.
Radiation Medicine Rounds is a trinary hard cover periodical designed to provide an up-to- date review of a dedicated radiation medicine topic of interest to clinicians and scientists who are involved in the care of patients receiving radiotherapy. It is intended to serve as both a reference and instructional tool for students, housestaff, fellows, practicing clinicians, medical physicists, cancer biologists, radiobiologists, and interdisciplinary colleagues throughout the oncology spectrum. This issue of Radiation Medicine Rounds discusses the more salient topics surrounding the role of radiation therapy for hematologic malignancies. There are literally dozens of distinct lymphoma subtypes, each with its own unique molecular and clinical features. Although systemic cytotoxic and targeted therapies have improved dramatically, radiation therapy remains an important modality for optimal clinical outcomes. With contributions from nationally recognized experts, Hematologic Malignancies offers an overview of the full spectrum of therapy for hematologic malignancies ranging from lymphoma and leukemia to plasma cell dyscrasias. Recent advances in radiotherapy for hematologic malignancies allow for maintenance of excellent local control with improvements in toxicity achieved through reductions in field sizes, in dose delivered, and increasingly conformal delivery techniques. Hematologic Malignancies provides the practitioner with a current overview of best practices, recent research, and future directions in the management of these complex cancers.
PET in the Management of Hematologic Malignancies, An Issue of PET Clinics by Abass Alavi,Gary Ulaner,Jakub Svoboda,Lale Kostakoglu Pdf
This issue of PET Clinics focuses on PET in the Management of Hematologic Malignancies and is edited by Drs. Abass Alavi (the Consulting Editor of PET Clinics), Gary Ulaner, Jakub Svoboda, and Lale Kostakoglu. Articles will include: PET-CR as a surrogate to replace PFS in assessment of efficacy of DLBCL treatments; PET-Derived Quantitative Metrics for Response and Prognosis; Evolving Role of PET Based Novel Quantitative Techniques in the Management of Hematological Malignancies; Critical Role of FDG/NaF imaging in Assessment of Skeletal Involvement in Patients with Multiple Myeloma; Response adapted treatment strategies in Hodgkin lymphoma using PET scans; FDG PET/CT as a staging tool in multiple myeloma; FDG PET/CT as a predictor of prognosis in multiple myeloma; PET/CT as a response evaluation tool in multiple myeloma; PET imaging in CLL and Richter’s transformation; Current Overview and Future Directions of PET for Hematologic Malignancies; and more!
Hematologic Malignancies by Michael B. Tomblyn, MD,Karen M. Winkfield, MD, PhD,Bouthaina Dabaja, MD Pdf
Radiation Medicine Rounds is a trinary hard cover periodical designed to provide an up-to- date review of a dedicated radiation medicine topic of interest to clinicians and scientists who are involved in the care of patients receiving radiotherapy. It is intended to serve as both a reference and instructional tool for students, housestaff, fellows, practicing clinicians, medical physicists, cancer biologists, radiobiologists, and interdisciplinary colleagues throughout the oncology spectrum. This issue of Radiation Medicine Rounds discusses the more salient topics surrounding the role of radiation therapy for hematologic malignancies. There are literally dozens of distinct lymphoma subtypes, each with its own unique molecular and clinical features. Although systemic cytotoxic and targeted therapies have improved dramatically, radiation therapy remains an important modality for optimal clinical outcomes. With contributions from nationally recognized experts, Hematologic Malignancies offers an overview of the full spectrum of therapy for hematologic malignancies ranging from lymphoma and leukemia to plasma cell dyscrasias. Recent advances in radiotherapy for hematologic malignancies allow for maintenance of excellent local control with improvements in toxicity achieved through reductions in field sizes, in dose delivered, and increasingly conformal delivery techniques. Hematologic Malignancies provides the practitioner with a current overview of best practices, recent research, and future directions in the management of these complex cancers. "
Case Studies in Hematologic Malignancies by Ronan Allen Pdf
Hematologic malignancies, also known as blood cancers, refer to a wide range of cancers that originate in the bone marrow or the lymphatic system. These cancers can affect the production and function of blood cells, including white blood cells, red blood cells and platelets. Hematologic malignancies include leukemia, lymphoma, and multiple myeloma. The treatment of hematologic malignancies depends on the specific type and stage of the cancer, as well as individual patient factors. These malignancies can be treated through radiation therapy, chemotherapy, immunotherapy, targeted therapy and stem cell transplantation. Radiation therapy uses high-energy radiation to target and kill cancer cells. Chemotherapy makes use of powerful medications to destroy cancer cells or prevent their growth. This book brings forth some of the most innovative concepts and elucidates the unexplored aspects of hematological malignancies. It will serve as a valuable source of reference for graduate and postgraduate students.
Radiological Imaging in Hematological Malignancies by Ali Guermazi Pdf
One of the first book’s to deal specifically with imaging of the entire spectrum of hematological malignancies. The use of the latest imaging modalities is well described, and an important aspect of the book is the role of imaging techniques in differentiating between manifestations of the underlying disease and complications of treatment. Each of the 28 chapters is written by an internationally recognized expert, making this book the most current and complete treatment of this subject available. Includes many high-quality radiological and histological illustrations. It should be of great interest to radiologists and hematologists.
Ravi A. Chandra,Lisa A. Kachnic,Charles R. Thomas JR
Author : Ravi A. Chandra,Lisa A. Kachnic,Charles R. Thomas JR Publisher : Elsevier Health Sciences Page : 337 pages File Size : 53,6 Mb Release : 2019-11-28 Category : Medical ISBN : 9780323697491
Contemporary Topics in Radiation Medicine, Pt II: Disease Sites , An Issue of Hematology/Oncology Clinics of North America E-Book by Ravi A. Chandra,Lisa A. Kachnic,Charles R. Thomas JR Pdf
This issue of Hematology/Oncology Clinics, guest edited by Ravi A. Chandra, Lisa A. Kachnic, and Charles R. Thomas, Jr., is the second volume of Contemporary Topics in Radiation Medicine, with focus on Disease Sites. This issue is one of six selected each year by our series consulting editors, Dr. George P. Canellos and Dr. Edward J. Benz. Topics discussed in this issue will include: Breast, Central Nervous System, GI, Genitourinary/Prostate, Gynecologic, Head & Neck, Thoracic, Hematologic cancers (including Leukemias, Lymphomas), Pediatric Cancer, Sarcoma/STS, Skin, Oligometastatic Disease, Palliation & Supportive Care & Inpatient Medicine, Radiation Emergencies, among others.
Seymour H Levitt,Seymour H. Levitt,James A. Purdy,Carlos A. Perez,S. Vijayakumar
Author : Seymour H Levitt,Seymour H. Levitt,James A. Purdy,Carlos A. Perez,S. Vijayakumar Publisher : Springer Science & Business Media Page : 884 pages File Size : 47,9 Mb Release : 2008-02-07 Category : Medical ISBN : 3540769110
Hematopoietic Cell Transplantation for Malignant Conditions by Qaiser Bashir,Mehdi Hamadani Pdf
Get a quick, expert overview of hematologic and non-hematologic malignancies for which hematopoietic cell transplantation is a treatment option. Drs. Qaiser Bashir and Mehdi Hamadani provide easy-to-find information on basic science of hematopoietic cell transplantation, pharmacology, workflows and procedures, possible complications and side effects, in addition to the role of HCT in conjunction with clinical cellular therapy. Discusses high-dose chemotherapeutic regimens and radiation therapy, patient and donor selection and workup, as well as other key aspects of hematopoietic cell transplantation. Includes practical information on complications, infectious disease, and special populations such as patients with HIV infection. Consolidates today’s available information in this fast-changing area into one convenient resource.
Total Marrow Irradiation by Jeffrey Y. C. Wong,Susanta K. Hui Pdf
This book, written by a team of international experts, concisely reviews the rationale and clinical application of image-guided total marrow irradiation, a rapidly emerging area in radiation oncology and hematopoietic cell transplantation. The aim is to provide the practicing radiation oncologist, hematologist, medical physicist, and bone marrow transplant researcher with a fundamental understanding of key aspects and an appreciation of the increasing significance of total marrow irradiation as conditioning for bone marrow transplantation. Detailed attention is paid to the impacts of recent advances in radiation therapy technology, functional PET and MRI, and understanding of the response of bone marrow to radiation. Full consideration is also given to the ways in which technological advances in image-guided radiation therapy have created new opportunities to treat bone marrow transplant patients with limited transplant options due to advanced disease, age, or co-morbidities. Further topics covered include the ways in which cancer stem cells and the marrow microenvironment influence response to radiation therapy and the implementation of new-generation predictive radiobiologic factors in the clinic.
Oncologic Therapies by Everett E. Vokes,Harvey M. Golomb Pdf
This second edition has been updated in a user-friendly layout that makes its comprehensive information extremely accessible. The handbook, written for all physicians who treat cancer patients, provides a survey of current therapeutic concepts of solid tumors and hematologic malignancies in internal oncology. Each individual chapter of this shortened new edition is structured in the same way and features a brief outline or tabular summary of the main aspects of epidemiology, pathology, staging, and diagnosis. The main focus is on the therapeutic strategy, i.e., an interdisciplinary approach to systemic drug therapy. Surgical and radiological concepts of treatment are also covered, as are supportive care, pain relief methods and ethical problems. This title is a must for clinicians and practitioners as well as interns, residents and postgraduate students.
National Academies of Sciences Engineering and Medicine,Health and Medicine Division,Board on Health Care Services,Committee on Childhood Cancers and Disability
Author : National Academies of Sciences Engineering and Medicine,Health and Medicine Division,Board on Health Care Services,Committee on Childhood Cancers and Disability Publisher : Unknown Page : 128 pages File Size : 53,7 Mb Release : 2021-09-09 Category : Electronic ISBN : 0309683491
Childhood Cancer and Functional Impacts Across the Care Continuum by National Academies of Sciences Engineering and Medicine,Health and Medicine Division,Board on Health Care Services,Committee on Childhood Cancers and Disability Pdf
Since the late 1960s, the survival rate in children and adolescents diagnosed with cancer has steadily improved, with a corresponding decline in the cancer-specific death rate. Although the improvements in survival are encouraging, they have come at the cost of acute, chronic, and late adverse effects precipitated by the toxicities associated with the individual or combined use of different types of treatment (e.g., surgery, radiation, chemotherapy). In some cases, the impairments resulting from cancer and its treatment are severe enough to qualify a child for U.S. Social Security Administration disability benefits. At the request of Social Security Administration, Childhood Cancer and Functional Impacts Across the Care Continuum provides current information and findings and conclusions regarding the diagnosis, treatment, and prognosis of selected childhood cancers, including different types of malignant solid tumors, and the effect of those cancers on childrenâ (TM)s health and functional capacity, including the relative levels of functional limitation typically associated with the cancers and their treatment. This report also provides a summary of selected treatments currently being studied in clinical trials and identifies any limitations on the availability of these treatments, such as whether treatments are available only in certain geographic areas.
Immunoconjugate Therapy of Hematologic Malignancies by Steven T. Rosen,Timothy M. Kuzel Pdf
The hybridoma technique for producing monoclonal antibodies developed by Drs. Kohler and Millstein in 1975 revolutionized the field of tumor immunology. It is now clear that there are antigens associated with or restricted to human neoplasms that have biologic significance. Monoclonal antibodies have already been demonstrated to have great immunodiagnostic value, and it is anticipated that they will become a component of our therapeutic armamentarium. Most investigators in the field, however, feel the true potential of monoclonal antibodies in cancer therapy remains to be determined. Clearly the most encouraging results have been witnessed in the treatment of hematologic malignancies. This volume of Cancer Treatment and Research explores the current state of the art of immunoconjugate therapy of hematologic malignancies. The first chapter, authored by Drs. Rosen and Kuzel, reviews the current status of radioimmunotherapy of lymphoma. Results of clinical investigations utilizing radiolabeled immunoconjugates in B-cell lymphomas, T-cell lym- phomas, and Hodgkin's disease are discussed. In addition, obstacles to effective antibody therapy are highlighted and toxicities are summarized. Chapter 2, written by Drs. Sgouros and Scheinberg, critiques the treat- ment of leukemia with radiolabeled monoclonal antibodies. In this chapter, the unique features of leukemia that make it particularly suitable for radio- immunotherapy are discussed, an overview of selected clinical trials is presented, and a treatment planning approach to radioimmunotherapy in- corporating biologic and physical parameters is reviewed.
Clinical Radiation Oncology by Leonard L. Gunderson, MD, MS, FASTRO,Joel E. Tepper, MD Pdf
Perfect for radiation oncology physicians and residents needing a multidisciplinary, treatment-focused resource, this updated edition continues to provide the latest knowledge in this consistently growing field. Not only will you broaden your understanding of the basic biology of disease processes, you'll also access updated treatment algorithms, information on techniques, and state-of-the-art modalities. The consistent and concise format provides just the right amount of information, making Clinical Radiation Oncology a welcome resource for use by the entire radiation oncology team. Content is templated and divided into three sections -- Scientific Foundations of Radiation Oncology, Techniques and Modalities, and Disease Sites - for quick access to information. Disease Sites chapters summarize the most important issues on the opening page and include a full-color format, liberal use of tables and figures, a closing section with a discussion of controversies and problems, and a treatment algorithm that reflects the treatment approach of the authors. Chapters have been edited for scientific accuracy, organization, format, and adequacy of outcome data (such as disease control, survival, and treatment tolerance). Allows you to examine the therapeutic management of specific disease sites based on single-modality and combined-modality approaches. Features an emphasis on providing workup and treatment algorithms for each major disease process, as well as the coverage of molecular biology and its relevance to individual diseases. Two new chapters provide an increased emphasis on stereotactic radiosurgery (SRS) and stereotactic body irradiation (SBRT). New Associate Editor, Dr. Andrea Ng, offers her unique perspectives to the Lymphoma and Hematologic Malignancies section. Key Points are summarized at the beginning of each disease-site chapter, mirroring the template headings and highlighting essential information and outcomes. Treatment algorithms and techniques, together with discussions of controversies and problems, reflect the treatment approaches employed by the authors. Disease Site Overviews allow each section editor to give a unique perspective on important issues, while online updates to Disease Site chapters ensure your knowledge is current. Disease Site chapters feature updated information on disease management and outcomes. Four videos accessible on Expert Consult include Intraoperative Irradiation, Prostate Brachytherapy, Penile Brachytherapy, and Ocular Melanoma. Thirty all-new anatomy drawings increase your visual understanding. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
Management of rare adult tumours by Yazid Belkacemi,René-Olivier Mirimanoff,Mahmut Ozsahin Pdf
Why a book dedicated to rare cancer management? Given the large variety of rare cancers,they take up a significant part of our daily practice. Therefore, we owe it to our patients with rare tumours that we use the knowledge gained in the treatment of the more common cancers to provide them with a better future. This knowledge comes from recent developments in molecular diagnostics, systemic treatments with new drugs and targeted therapies together with advanced technologies in the areas of radiology and radiation therapy. Our authors have analysed the literature and recommend treatments for rare cancers based on results from past studies. We hope that this book will be an aid to those treating rare cancer cases about which, up to now, little has been published, and will reassure our patients that they have not been forgotten.
