Hematologic Malignancies

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Hematologic Malignancies in Adults

MiKaela M. Olsen,Laura J. Zitella
Hematologic Malignancies in Adults Book PDF

Author : MiKaela M. Olsen,Laura J. Zitella
Publisher : Unknown
Page : 0 pages
File Size : 52,5 Mb
Release : 2013
Category : Hematopoietic system
ISBN : 1935864262

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Hematologic Malignancies in Adults by MiKaela M. Olsen,Laura J. Zitella Pdf

More than 180 years since Thomas Hodgkin identified the first hematologic malignancy, nurses are still learning the best ways to treat patients with these complex cancers. Hematologic Malignancies in Adults gives you comprehensive information on treatments, complications, and toxicity management for your everyday practice. The book focuses on the management of disease-related manifestations and treatment-related side effects and toxicities. You'll find details on forms of hematologic malignancies, including leukemia and lymphoma, Hodgkin lymphoma, mature T-cell and NK-cell neoplasms, and multiple myeloma. Also included is a chapter on vascular access and a listing of drugs used in the treatment of hematologic malignancies. The management of patients with myeloid and lymphoid neoplasms is unique, complex, and vital to ensuring successful outcomes and improved quality of life. This book gives you every tool you need to keep pace with the advances in medicine and science as you trea

Handbook of Hematologic Malignancies

David A. Sallman,Ateefa Chaudhury,Johnny Nguyen,Ling Zhang,Alan F. List
Handbook of Hematologic Malignancies Book PDF

Author : David A. Sallman,Ateefa Chaudhury,Johnny Nguyen,Ling Zhang,Alan F. List
Publisher : Demos Medical Publishing
Page : 0 pages
File Size : 43,7 Mb
Release : 2017
Category : Lymphoproliferative disorders
ISBN : 1620700948

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Handbook of Hematologic Malignancies by David A. Sallman,Ateefa Chaudhury,Johnny Nguyen,Ling Zhang,Alan F. List Pdf

MDS/MPN With Ring Sideroblasts and Thrombocytosis

Molecular Aspects of Hematologic Malignancies

Michal Witt,Malgorzata Dawidowska,Tomasz Szczepanski
Molecular Aspects of Hematologic Malignancies Book PDF

Author : Michal Witt,Malgorzata Dawidowska,Tomasz Szczepanski
Publisher : Springer Science & Business Media
Page : 468 pages
File Size : 49,5 Mb
Release : 2012-06-30
Category : Science
ISBN : 9783642294679

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Molecular Aspects of Hematologic Malignancies by Michal Witt,Malgorzata Dawidowska,Tomasz Szczepanski Pdf

This book provides a state-of-the-art approach to the molecular basis of hematologic diseases and its translation into improved diagnostics and novel therapeutic strategies. Several representative hemato-oncologic malignancies are analyzed in detail: acute lymphoblastic leukemia, acute myeloid leukemia, B-cell Non-Hodgkin lymphomas, multiple myeloma, chronic lymphocytic leukemia, chronic myeloid leukemia, myelodysplastic syndromes, and myeloproliferative neoplasms. Experts in the field describe the molecular methods applied for modern diagnostics and therapies, such as hematopoietic stem cell transplantation, donor recipient matching, banking of biological material, analyses of post-transplant chimerism, and minimal residual disease monitoring. The volume concludes with an extensive section comprising thorough step-by-step protocols of molecular techniques in hematology, all of them validated in the authors’ own laboratories.

Management of Hematologic Malignancies

Susan O'Brien,Julie M. Vose,Hagop M. Kantarjian
Management of Hematologic Malignancies Book PDF

Author : Susan O'Brien,Julie M. Vose,Hagop M. Kantarjian
Publisher : Cambridge University Press
Page : 527 pages
File Size : 41,8 Mb
Release : 2010-11-18
Category : Medical
ISBN : 9781139493659

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Management of Hematologic Malignancies by Susan O'Brien,Julie M. Vose,Hagop M. Kantarjian Pdf

Hematologic malignancies were the first human cancers to be studied in depth at the molecular level, and recent years have seen important advances in treatment. This comprehensive reference book covers the full range of hematologic malignancies, including all subtypes of leukemias, lymphomas, and plasma cell dyscrasias. Authored by internationally known experts, each chapter emphasizes diagnostic work-up, staging, and therapeutic approaches. Up-to-date hematopathology, treatment, and outcomes data are presented in a way which is directly applicable to patient care. Highly illustrated with color images, graphs, flowcharts and treatment algorithms, the book is perfect for quick clinical reference as well as providing detailed reference lists for further study. With its authoritative and practical focus and visually stimulating presentation, this is a key text for hematology and oncology fellows, physicians, oncology nurses, physician assistants and other healthcare workers in the field of oncology.

Hematologic Malignancies

Guy B. Faguet
Hematologic Malignancies Book PDF

Author : Guy B. Faguet
Publisher : Springer Science & Business Media
Page : 365 pages
File Size : 49,7 Mb
Release : 2008-02-02
Category : Medical
ISBN : 9781592590742

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Hematologic Malignancies by Guy B. Faguet Pdf

The aim of Hematologic Malignancies: Methods and Techniques is to review those methods most useful for the diagnosis and subsequent mana- ment of hematologic malignancies. The scope of coverage is intentionally broad, ranging from routine procedures to highly sophisticated methods not currently offered by most clinical laboratories. The latter methods were selected especially to bring into focus recent advances in molecular biology that, since they provide us with strong tools for assessing the outcome of upcoming therapeutic modalities intent on disease eradication, are expected to impact the future diagnosis and management of these diseases. Thus, the c- mon thread among all chapters is clinical relevance, whether sanctioned by past experience or by the expectation that seemingly esoteric research techniques of today will prove clinically valuable in the future. Hematologic Malignancies: Methods and Techniques is primarily a compilation of methods presented in sufficient detail—by authors with extensive expertise in their field—to serve not only as a reference for seasoned research and clinical laboratory pers- nel, but also as a guide for the less experienced. Moreover, the contributing authors also discuss the pathophysiologic bases and the diagnostic usefulness that underscore each method’s clinical relevance. Thus, this volume should be also valuable to clinicians—especially hematologists, oncologists, and path- ogists—often bewildered by an ever increasing flow of new scientific inf- mation, the practical application of which is often either not clearly disclosed or difficult to discern.

Hematologic Malignancies

Manorama Bhargava
Hematologic Malignancies Book PDF

Author : Manorama Bhargava
Publisher : Springer Nature
Page : 246 pages
File Size : 48,7 Mb
Release : 2021-02-13
Category : Medical
ISBN : 9789813347991

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Hematologic Malignancies by Manorama Bhargava Pdf

This book is a compendium of case studies in hematologic malignancies such as acute leukemias, myelodysplastic and myeloproliferative neoplasms, chronic leukemias and multiple myeloma covering cytogenetics (karyotyping Fluorescence in sitn hybridization (FISH)) and molecular studies in detail. The first few chapters describe the methodology employed for karyotyping, FISH and Real Time PCR technology conducive to establishment of these labs if required. Each case study is described in detail by including the clinical history of the patient, findings of peripheral blood, bone marrow aspirate and bone biopsy morphological details. This is then followed by flowcytometric immunophenotyping, cytogenetic and molecular observations leading collectively to a final diagnosis, A discussion follows based on the relevance of this data in informing the prognosis, treatment response and survival in these patients. Additionally, this data serves as a key determinant for clinical decision making involving evidence based rational management of patients including targeted therapy. For better understanding, each case study is accompanied by black and white or colour images as appropriate. This book is a source of learning and a valuable read for clinical hematologists, hematopathologists, medical oncologists, residents, interns, DM Hematology students and DNB Hematology students as well.

Hematologic Malignancies: Acute Leukemias

S.H. Faderl,H.M. Kantarjian
Hematologic Malignancies Acute Leukemias Book PDF

Author : S.H. Faderl,H.M. Kantarjian
Publisher : Springer Science & Business Media
Page : 302 pages
File Size : 53,9 Mb
Release : 2007-11-21
Category : Medical
ISBN : 9783540723042

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Hematologic Malignancies: Acute Leukemias by S.H. Faderl,H.M. Kantarjian Pdf

Better therapy of acute leukemias depends ultimately on better understanding of the distinction between leukemic and normal progenitor cells. This hugely important new book describes the current knowledge of acute leukemia biology and discusses new classification systems that have arisen as a result of emerging insights into pathogenesis. Estey, Faderl and Kantarjian, who all work at the respected Anderson Cancer Center in Houston, Texas, USA, examine in detail advances in the treatment of particular types of acute leukemia. Their book also covers the management of acute leukemia in general as well as the development of new therapies. This book will be extremely useful to clinicians.

Multiparameter Flow Cytometry in the Diagnosis of Hematologic Malignancies

Anna Porwit,Marie Christine Béné
Multiparameter Flow Cytometry in the Diagnosis of Hematologic Malignancies Book PDF

Author : Anna Porwit,Marie Christine Béné
Publisher : Cambridge University Press
Page : 247 pages
File Size : 52,8 Mb
Release : 2018-01-25
Category : Medical
ISBN : 9781107503830

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Multiparameter Flow Cytometry in the Diagnosis of Hematologic Malignancies by Anna Porwit,Marie Christine Béné Pdf

This practical manual offers an active understanding of how to implement flow-cytometry when facing complex, haematological diseases.

Childhood Cancer and Functional Impacts Across the Care Continuum

National Academies of Sciences Engineering and Medicine,Health and Medicine Division,Board on Health Care Services,Committee on Childhood Cancers and Disability
Childhood Cancer and Functional Impacts Across the Care Continuum Book PDF

Author : National Academies of Sciences Engineering and Medicine,Health and Medicine Division,Board on Health Care Services,Committee on Childhood Cancers and Disability
Publisher : Unknown
Page : 128 pages
File Size : 52,9 Mb
Release : 2021-09-09
Category : Electronic
ISBN : 0309683491

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Childhood Cancer and Functional Impacts Across the Care Continuum by National Academies of Sciences Engineering and Medicine,Health and Medicine Division,Board on Health Care Services,Committee on Childhood Cancers and Disability Pdf

Since the late 1960s, the survival rate in children and adolescents diagnosed with cancer has steadily improved, with a corresponding decline in the cancer-specific death rate. Although the improvements in survival are encouraging, they have come at the cost of acute, chronic, and late adverse effects precipitated by the toxicities associated with the individual or combined use of different types of treatment (e.g., surgery, radiation, chemotherapy). In some cases, the impairments resulting from cancer and its treatment are severe enough to qualify a child for U.S. Social Security Administration disability benefits. At the request of Social Security Administration, Childhood Cancer and Functional Impacts Across the Care Continuum provides current information and findings and conclusions regarding the diagnosis, treatment, and prognosis of selected childhood cancers, including different types of malignant solid tumors, and the effect of those cancers on childrenâ (TM)s health and functional capacity, including the relative levels of functional limitation typically associated with the cancers and their treatment. This report also provides a summary of selected treatments currently being studied in clinical trials and identifies any limitations on the availability of these treatments, such as whether treatments are available only in certain geographic areas.

Radiation Therapy in Hematologic Malignancies

Bouthaina Shbib Dabaja,Andrea K. Ng
Radiation Therapy in Hematologic Malignancies Book PDF

Author : Bouthaina Shbib Dabaja,Andrea K. Ng
Publisher : Springer
Page : 203 pages
File Size : 41,7 Mb
Release : 2016-10-26
Category : Medical
ISBN : 9783319426150

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Radiation Therapy in Hematologic Malignancies by Bouthaina Shbib Dabaja,Andrea K. Ng Pdf

This book is designed to assist practitioners in managing patients who present with difficult cases of the most common hematological malignancies. The scenarios covered are those that are likely to be encountered in patients with the various forms of Hodgkin’s lymphoma, non-Hodgkin’s lymphoma, and leukemia. In each of the three sections devoted to these malignancies, multiple cases are presented. The case discussions follow a standard format. A clinical description is followed by a pathological description documenting information relevant to diagnosis and by details of staging work-up, including images. The treatment options are then discussed at length, highlighting relevant literature for each option. Finally, the treatment delivered is identified and images of the planning technique/modality used are provided. This book will be an invaluable aid to decision making for radiation oncologists and will also be of interest for hematologists.

Acute Leukemias

Stefan H. Faderl,Hagop M. Kantarjian,Elihu Estey
Acute Leukemias Book PDF

Author : Stefan H. Faderl,Hagop M. Kantarjian,Elihu Estey
Publisher : Springer Nature
Page : 283 pages
File Size : 55,6 Mb
Release : 2020-10-10
Category : Medical
ISBN : 9783030536336

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Acute Leukemias by Stefan H. Faderl,Hagop M. Kantarjian,Elihu Estey Pdf

Better therapy of acute leukemias depends ultimately on better understanding of the distinction between leukemic and normal progenitor cells. This hugely important new book describes the current knowledge of acute leukemia biology and discusses new classification systems that have arisen as a result of emerging insights into pathogenesis. Estey, Faderl and Kantarjian, who all work at the respected Anderson Cancer Center in Houston, Texas, USA, examine in detail advances in the treatment of particular types of acute leukemia. Their book also covers the management of acute leukemia in general as well as the development of new therapies. This book will be extremely useful to clinicians.

Flow Cytometry of Hematological Malignancies

Claudio Ortolani
Flow Cytometry of Hematological Malignancies Book PDF

Author : Claudio Ortolani
Publisher : John Wiley & Sons
Page : 464 pages
File Size : 42,7 Mb
Release : 2021-04-19
Category : Medical
ISBN : 9781119611301

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Flow Cytometry of Hematological Malignancies by Claudio Ortolani Pdf

Flow Cytometry of Hematological Malignancies Flow cytometric analysis is often integral to the swift and accurate diagnosis of leukemias and lymphomas of the blood, bone marrow, and lymph nodes. However, in the fast-moving and expanding field of clinical hematology, in can be challenging to remain up to speed with the latest biological research and technological innovations. Flow Cytometry of Hematological Malignancies has been designed to provide all those working in hematological oncology with a practical, cutting-edge handbook, featuring clear and fully illustrated guidance on all aspects of cytometry’s role in diagnosis and analysis. This essential second edition includes: Explorations of more than 70 antigens Full-color illustrations throughout New descriptions of recently discovered markers WHO classifications of hematological neoplastic diseases Helpful tips for result interpretation and analysis Featuring all this and more, Flow Cytometry of Hematological Malignancies, Second Edition, is an invaluable resource for both trainee and experienced hematologists, hematopathologists, oncologists, and pathologists, as well as medical students and diagnostic lab technicians.

Handbook of Benign Hematology

Martha Pritchett Mims, MD, PhD,Courtney Miller-Chism, MD,Iberia Romina Sosa, MD, PhD
Handbook of Benign Hematology Book PDF

Author : Martha Pritchett Mims, MD, PhD,Courtney Miller-Chism, MD,Iberia Romina Sosa, MD, PhD
Publisher : Springer Publishing Company
Page : 555 pages
File Size : 47,8 Mb
Release : 2019-12-11
Category : Medical
ISBN : 9780826149879

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Handbook of Benign Hematology by Martha Pritchett Mims, MD, PhD,Courtney Miller-Chism, MD,Iberia Romina Sosa, MD, PhD Pdf

Handbook of Benign Hematology is a practical guide to the diagnosis and management of benign hematologic conditions. The book begins with a chapter on normal hematopoiesis and follows with chapters devoted to groups of blood disorders and syndromes including neutrophil disorders, nonmalignant myeloid disorders, bone marrow failure syndromes, myeloproliferative disorders, anemias, iron metabolism disorders, platelet disorders, hemostasis and coagulation defects, and thrombosis. Each disorder subtype covered features a clinical case, an introduction to the condition, details on diagnosis including applicable criteria and lab work needed, key diagnostic dilemmas, prognosis, treatment options, details on clinical trials and emerging clinical strategies, and bulleted key points to highlight clinical pearls and common pitfalls. The final chapters provide best practices for transfusion medicine and a guide to pharmacologic agents and their uses in clinical practice for adult and pediatric patients. The handbook is filled with tables and illustrations which highlight FDA-approved drug information, clinical trials data, hematopathologic characteristics of different disorders, important management criteria and more, making it the ideal handbook for those in practice or for review. The Editors and chapter authors are experienced academic practitioners in the fields of adult and pediatric hematology, pathology, blood banking, and pharmacology. Emphasizing best practices for patient management, this handbook is essential for oncologists, hematologists, trainees, and other practitioners who regularly or increasingly receive referrals to diagnose and treat adults or children with nonmalignant hematologic conditions. Key Features: Includes dozens of clinical cases covering all nonmalignant blood disorders Emphasizes patient management and best practices for disorders seen in adults and children Contains over 30 color images and numerous tables for quick reference Presents important details of all pharmacologic agents used to treat or manage hematologic disorders and their complications Purchase includes access to the ebook for use on most mobile devices or computers

Radiological Imaging in Hematological Malignancies

Ali Guermazi
Radiological Imaging in Hematological Malignancies Book PDF

Author : Ali Guermazi
Publisher : Springer Science & Business Media
Page : 584 pages
File Size : 45,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642188329

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Radiological Imaging in Hematological Malignancies by Ali Guermazi Pdf

One of the first book’s to deal specifically with imaging of the entire spectrum of hematological malignancies. The use of the latest imaging modalities is well described, and an important aspect of the book is the role of imaging techniques in differentiating between manifestations of the underlying disease and complications of treatment. Each of the 28 chapters is written by an internationally recognized expert, making this book the most current and complete treatment of this subject available. Includes many high-quality radiological and histological illustrations. It should be of great interest to radiologists and hematologists.

Hematologic Malignancies

Blake Copland
Hematologic Malignancies Book PDF

Author : Blake Copland
Publisher : Unknown
Page : 358 pages
File Size : 49,6 Mb
Release : 2020
Category : Medical
ISBN : 1536181250

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Hematologic Malignancies by Blake Copland Pdf

"Ineffective hematopoiesis in bone marrow and peripheral cytopenias are features of bone marrow failure and related syndromes. These diseases can progress to myelodysplastic syndrome, acute myeloid leukemia, and other malignancies. Acute myeloid leukemia is a heterogeneous complex malignancy characterized by proliferating myeloblasts in the bone marrow and a diverse range of recurrent molecular aberrations that occur in many different combinations. More specifically, the authors explore the McDonough strain of feline sarcoma virus-related tyrosine kinase 3 receptor mutations present in about 30-35% of acute myeloid leukemia patients. The way in which the Wnt signaling pathway plays an important role in normal hematopoiesis and its deregulation associated with acute myeloid leukemia is also discussed. This compilation also explores the importance of residual leukemic cells in disease relapse prognosis, as the new definition of the European LeukemiaNet for complete remission includes minimal or measurable residual disease negativity. Mutations detected in patients with clonal hematopoiesis are addressed, including those which most commonly affect DNMT3A, ASXL1, TET2, JAK2, SF3B1, SRSF2, and TP53 genes that had previously been identified as drivers in various myeloid neoplasms. The authors provide an overview of the roles of extracellular vesicles in multiple myeloma, their capacity as emerging biomarkers, and implications for liquid biopsy for detection and monitoring. The penultimate study focuses on toll-like receptors, which play an essential role in the recognition of invading pathogens via specific microbial molecular motifs, forming a bridge between the innate and adaptive immune responses. In conclusion, this compilation explores PROTACs, proteolysis targeting chimeras, which mediate the degradation of proteins of interest by hijacking the activity of E3-ubiquitin ligases for POI polyubiquitination and subsequent degradation by proteasome"--