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Rapidly Evolving Genes and Genetic Systems by Rama S. Singh,Jianping Xu,Rob J. Kulathinal Pdf
A range of theories on the rates of evolution-from static to gradual to punctuated to quantum-have been developed, mostly by comparing morphological changes over geological timescales as described in the fossil record.
Rapidly Evolving Genes and Genetic Systems by Rama S. Singh,Jianping Xu,Rob J. Kulathinal Pdf
Ever since the pioneering work of Darwin and Wallace, evolutionary biologists have attempted to understand the evolutionary dynamics of genetic systems. A range of theories on evolutionary ratesfrom static to gradual to punctuated to quantumhave been developed, primarily by comparing morphological changes over geological timescales as described in the fossil record. Recent studies, however, are beginning to change the way that we view evolutionary patterns and processes. New paleontological, experimental, molecular, and genomic investigations are providing a tremendous amount of novel data and fresh perspectives, offering valuable insights on the rates of evolutionary change, particularly in fast-evolving genetic systems. Rapidly Evolving Genes and Genetic Systems captures these recent exciting developments across a broad range of morphological, molecular, cellular, developmental, and genetic investigations in both natural and experimental populations over a diversity of life forms. The book provides a fascinating series of case studies that exemplify rapid evolution, and showcases the diversity of rapidly evolving genes and genetic systems, emphasizing the extremely important roles that they play in adaptation, speciation, and the generation and maintenance of a diversity of biological traits and properties. This exciting collection showcases the latest research of more than 50 eminent evolutionary biologists. It will be suitable for senior undergraduate students, graduate students, researchers, and for all those interested in the study of evolution.
Originally published in 1987 Rates of Evolution is an edited collection drawn from a symposium convened to bring together palaeontologists, geneticists, molecular biologists and developmental biologists to examine some aspects of the problem of evolutionary rates. The book asks questions surrounding the study of evolution, such as did large morphological changes really occur rapidly at various times in the geological past, or is the fossil record too imperfect to be of value in assessing rates of morphological change? What is the measure of ‘rapid’ change? Is stasis at any taxonomic level established? Is it possible to relate genomic and morphological change? What is the role of regulatory and executive genes in controlling evolutionary change? Does the transfer of genetic material between different taxa provide the possibility of increasing evolutionary rates? Featuring contributions from leading researchers, this book will interest anthropologists, palaeontology and scientists of evolution and genetics.
In the Light of Evolution by National Academy of Sciences Pdf
The Arthur M. Sackler Colloquia of the National Academy of Sciences address scientific topics of broad and current interest, cutting across the boundaries of traditional disciplines. Each year, four or five such colloquia are scheduled, typically two days in length and international in scope. Colloquia are organized by a member of the Academy, often with the assistance of an organizing committee, and feature presentations by leading scientists in the field and discussions with a hundred or more researchers with an interest in the topic. Colloquia presentations are recorded and posted on the National Academy of Sciences Sackler colloquia website and published on CD-ROM. These Colloquia are made possible by a generous gift from Mrs. Jill Sackler, in memory of her husband, Arthur M. Sackler.
Robustness and Evolvability in Living Systems by Andreas Wagner Pdf
All living things are remarkably complex, yet their DNA is unstable, undergoing countless random mutations over generations. Despite this instability, most animals do not grow two heads or die, plants continue to thrive, and bacteria continue to divide. Robustness and Evolvability in Living Systems tackles this perplexing paradox. The book explores why genetic changes do not cause organisms to fail catastrophically and how evolution shapes organisms' robustness. Andreas Wagner looks at this problem from the ground up, starting with the alphabet of DNA, the genetic code, RNA, and protein molecules, moving on to genetic networks and embryonic development, and working his way up to whole organisms. He then develops an evolutionary explanation for robustness. Wagner shows how evolution by natural selection preferentially finds and favors robust solutions to the problems organisms face in surviving and reproducing. Such robustness, he argues, also enhances the potential for future evolutionary innovation. Wagner also argues that robustness has less to do with organisms having plenty of spare parts (the redundancy theory that has been popular) and more to do with the reality that mutations can change organisms in ways that do not substantively affect their fitness. Unparalleled in its field, this book offers the most detailed analysis available of all facets of robustness within organisms. It will appeal not only to biologists but also to engineers interested in the design of robust systems and to social scientists concerned with robustness in human communities and populations.
National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Life Sciences,Committee on Gene Drive Research in Non-Human Organisms: Recommendations for Responsible Conduct
Author : National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Life Sciences,Committee on Gene Drive Research in Non-Human Organisms: Recommendations for Responsible Conduct Publisher : National Academies Press Page : 231 pages File Size : 53,9 Mb Release : 2016-08-28 Category : Science ISBN : 9780309437875
Gene Drives on the Horizon by National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Life Sciences,Committee on Gene Drive Research in Non-Human Organisms: Recommendations for Responsible Conduct Pdf
Research on gene drive systems is rapidly advancing. Many proposed applications of gene drive research aim to solve environmental and public health challenges, including the reduction of poverty and the burden of vector-borne diseases, such as malaria and dengue, which disproportionately impact low and middle income countries. However, due to their intrinsic qualities of rapid spread and irreversibility, gene drive systems raise many questions with respect to their safety relative to public and environmental health. Because gene drive systems are designed to alter the environments we share in ways that will be hard to anticipate and impossible to completely roll back, questions about the ethics surrounding use of this research are complex and will require very careful exploration. Gene Drives on the Horizon outlines the state of knowledge relative to the science, ethics, public engagement, and risk assessment as they pertain to research directions of gene drive systems and governance of the research process. This report offers principles for responsible practices of gene drive research and related applications for use by investigators, their institutions, the research funders, and regulators.
Abstracts of Publications by National Science Foundation (U.S.). Division of Intergovernmental Science & Public Technology Pdf
Summarizes the publications that have resulted from the activities that have been sponsored in State and local governments and in technologically-oriented institutions around the country in the Intergovernmental Science Program.