Reactive Intermediate Chemistry

Author : Matthew S. Platz,Robert A. Moss,Maitland Jones, Jr.
Publisher : John Wiley & Sons
Page : 492 pages
File Size : 48,5 Mb
Release : 2007-04-20
Category : Science
ISBN : 9780470120811

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Reviews of Reactive Intermediate Chemistry by Matthew S. Platz,Robert A. Moss,Maitland Jones, Jr. Pdf

The chemistry of reactive intermediates is central to a modern mechanistic and quantitative understanding of organic chemistry. Moreover, it underlies a significant portion of modern synthetic chemistry and is integral to a molecular view of biological chemistry. Reviews in Reactive Intermediate Chemistry presents an up-to-date, authoritative guide to this fundamental topic. Although it follows Reactive Intermediate Chemistry by the same authors, it serves as a free-standing resource for the entire chemical and biochemical community. The book includes: Relevant, practical applications Coverage of such topics as mass spectrometry methods, reactive intermediates in interstellar medium, quantum mechanical tunnelling, solvent effects, reactive intermediates in biochemical processes, and excited state surfaces Discussions of emerging areas, particularly those involving dynamics and theories Concluding sections identifying key directions for future research are provided at the end of each chapter

Author : Robert A. Moss,Matthew S. Platz,Maitland Jones, Jr.
Publisher : John Wiley & Sons
Page : 1088 pages
File Size : 55,8 Mb
Release : 2004-01-07
Category : Science
ISBN : 0471233242

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Reactive Intermediate Chemistry by Robert A. Moss,Matthew S. Platz,Maitland Jones, Jr. Pdf

Reactive Intermediate Chemistry presents a detailed and timely examination of key intermediates central to the mechanisms of numerous organic chemical transformations. Spectroscopy, kinetics, and computational studies are integrated in chapters dealing with the chemistry of carbocations, carbanions, radicals, radical ions, carbenes, nitrenes, arynes, nitrenium ions, diradicals, etc. Nanosecond, picosecond, and femtosecond kinetic realms are explored, and applications of current dynamics and electronic structure calculations are examined. Reactive Intermediate Chemistry provides a deeper understanding of contemporary physical organic chemistry, and will assist chemists in the design of new reactions for the efficient synthesis of pharmaceuticals, fine chemicals, and agricultural products. Among its features, this authoritative volume is: Edited and authored by world-renowned leaders in physical organic chemistry. Ideal for use as a primary or supplemental graduate textbook for courses in mechanistic organic chemistry or physical chemistry. Enhanced by supplemental reading lists and summary overviews in each chapter.

Author : Maya Shankar Singh
Publisher : John Wiley & Sons
Page : 296 pages
File Size : 55,5 Mb
Release : 2014-01-22
Category : Science
ISBN : 9783527678273

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Reactive Intermediates in Organic Chemistry by Maya Shankar Singh Pdf

Most reactions in organic chemistry do not proceed in a single step but rather take several steps to yield the desired product. In the course of these multi-step reaction sequences, short-lived intermediates can be generated that quickly convert into other intermediates, reactants, products or side products. As these intermediates are highly reactive, they cannot usually be isolated, but their existence and structure can be proved by theoretical and experimental methods. Using the information obtained, researchers can better understand the underlying reaction mechanism of a certain organic transformation and thus develop novel strategies for efficient organic synthesis. The chapters are clearly structured and are arranged according to the type of intermediate, providing information on the formation, characterization, stereochemistry, stability, and reactivity of the intermediates. Additionally, representative examples and a problem section with different levels of difficulty are included for self-testing the newly acquired knowledge. By providing a deeper understanding of the underlying concepts, this is a musthave reference for PhD and Master Students in organic chemistry, as well as a valuable source of information for chemists in academia and industry working in the field. It is also ideal as primary or supplementary reading for courses on organic chemistry, physical organic chemistry or analytical chemistry.

Author : Neil S. Isaacs
Publisher : John Wiley & Sons
Page : 572 pages
File Size : 50,7 Mb
Release : 1974
Category : Chemical reactions
ISBN : UCAL:B4476790

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Reactive Intermediates in Organic Chemistry by Neil S. Isaacs Pdf

Author : Curt Wentrup
Publisher : Wiley-Interscience
Page : 360 pages
File Size : 54,8 Mb
Release : 1984-03-21
Category : Science
ISBN : UCAL:B4476799

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Reactive Molecules by Curt Wentrup Pdf

Designed for advanced undergraduate and graduate organic chemistry students, here's an up-to-date, in-depth textbook on the chemistry of neutral reactive intermediates--free radicals, diradicals, carbenes, nitrenes, strained rings, and antiaromatics. Includes numerous tables of physical data and extensive references to present day research in the field.

Author : Samuel McManus
Publisher : Elsevier
Page : 552 pages
File Size : 41,5 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323146272

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Organic reactive intermediates by Samuel McManus Pdf

Organic Chemistry: A Series of Monographs, Volume 26: Organic Reactive Intermediates focuses on the study of reactive intermediates. This book discusses the methods of formation and investigation, factors affecting the stability, and reactions of the intermediate. Other topics include the formation and reaction of free radicals; kinetic aspects of free-radical chain reactions; electronic states and structures of carbenes; and formation of transient carbenes and carbenoids in solution. The intermediacy of nitrenes in reactions; electronic structure and spectra; methods of investigating carbonium ions; and reactions of carbonium ions are also elaborated. This publication likewise covers the preparation of carbanions; factors affecting the stability of carbanions; reactions involving radical ions; and methods of investigating arynes. This volume serves as a textbook for the first graduate-level course, as well as a reference for industrial chemists interested in organic reaction mechanisms.

Author : N. S. Isaacs
Publisher : Unknown
Page : 550 pages
File Size : 51,7 Mb
Release : 1979
Category : Electronic
ISBN : OCLC:1123525895

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Reactive Intermediates in Organic Chemistry by N. S. Isaacs Pdf

Author : Patrick M. Dansette,Robert R. Snyder,Terrence J. Monks,David J. Jollow,I. Glenn Sipes,Helmut Greim,G. Gordon Gibson,Marcel Delaforge
Publisher : Springer Science & Business Media
Page : 716 pages
File Size : 54,5 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461506676

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Biological Reactive Intermediates Vi by Patrick M. Dansette,Robert R. Snyder,Terrence J. Monks,David J. Jollow,I. Glenn Sipes,Helmut Greim,G. Gordon Gibson,Marcel Delaforge Pdf

This volume presents a discussion of the biological effects produced following the metabolism of xenobiotic chemicals to chemically reactive metabolites, i.e., toxic and carcinogenic effects, which have been the basis of all five earlier volumes in this series. In particular, this volume devotes sections to structure-activity relationships, recent advances in the understanding of the chemistry of reactive metabolites, and the generation and activity of reactive oxygen species with special emphasis on nitric oxide. There are also segments on DNA damage by reactive metabolites and DNA repair, tissue specific responses to BRIs, and human health effects of BRIs. The papers that comprise this volume were submitted by world class scientists who were in attendance at The Symposium on Biological Reactive Intermediates VI at the Université René Descartes, July 16-20, 2000.

Author : Christopher J. Moody,Gordon Harlow Whitham
Publisher : Unknown
Page : 91 pages
File Size : 43,5 Mb
Release : 2006
Category : Intermediates (Chemistry)
ISBN : 0191848905

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Reactive Intermediates by Christopher J. Moody,Gordon Harlow Whitham Pdf

Neutral reactive intermediates play a key role in synthetic chemistry. This primer concentrates on this role; the important reactions of these electron-deficient species are laid out clearly and simply, with carefully chosen examples illustrating their use in organic synthesis. Each chapter includes a few problems as well as suggestions for further reading, and provides undergraduates with an invaluable summary of this important topic in organic chemistry.

Author : Christopher J. Moody,Gordon Harlow Whitham
Publisher : Oxford University Press on Demand
Page : 89 pages
File Size : 40,7 Mb
Release : 1992
Category : Science
ISBN : 0198556721

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Reactive Intermediates by Christopher J. Moody,Gordon Harlow Whitham Pdf

Neutral reactive intermediates -- radicals, carbenes, nitrenes, and aryenes -- occupy a fascinating place in the history of organic chemistry. First regarded as mere curiosities, neutral reactive intermediates ultimately came under the intense scrutiny of physical organic chemists from a mechanistic point-of-view. This concise text concentrates on how these electron-deficient species now play a key role in synthetic chemistry research. Important reactions are clearly and simply laid out with carefully chosen examples that illustrate their use in organic synthesis. Each chapter includes problems as well as suggestions for further reading. Undergraduates will find Reactive Intermediates an invaluable summary of this important topic in organic chemistry--one that fills a gap created by the superficial treatment accorded these valuable compounds in most chemistry textbooks.

Author : R.A. Abramovitch
Publisher : Springer Science & Business Media
Page : 640 pages
File Size : 50,9 Mb
Release : 2013-11-09
Category : Science
ISBN : 9781461334279

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Reactive Intermediates by R.A. Abramovitch Pdf

The field of reactive intermediates has been blossoming at a rapid rate in recent years and its impact on chemistry, both "pure" and "applied," as well as on biology, astronomy, and other areas of science, is enormous. Several books have been published which cover the area; one, edited by McManus, * surveys the subject in general at the senior undergraduate or beginning graduate level. In addition, a number of monographs have appeared which deal with individual topics such as carbenes, nitrenes, free radicals, carbanions, carbenium ions, and so on, in great depth. Our objective is somewhat different. We hope that these Advances in . . . type of volumes will appear at irregular intervals of a year to 18 months each. We intend to publish up-to-date reviews in relatively new areas of the chemistry of reactive intermediates. These will be written by world authorities in the field, each one of whom will give the reader a current in-depth review of all aspects of the chemistry of each of these species. It is our plan that the subjects to be reviewed will cover not only organic chemistry but also inorganic, physical, bio-, industrial, and atmospheric chemistry. The volumes themselves, we hope, will end up being reasonably interdisciplinary, though this need not and probably will not be the case for the individual reviews.

Author : Narain R. P.
Publisher : PHI Learning Pvt. Ltd.
Page : 279 pages
File Size : 50,9 Mb
Release : 2011-03
Category : Science
ISBN : 9788120341791

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Fundamentals of Reaction Mechanisms in Organic Chemistry by Narain R. P. Pdf

Written for the undergraduate and postgraduate students of chemistry, this textbook presents comprehensive coverage of different types of reactions and their mechanisms. The need for such a book has been felt for a very long time both by students and teachers. The book discusses chemical kinetics, structure and reactivity, and reactive intermediates such as carbenes, nitrenes and benzynes. It also describes the mechanism of tautomerism and the concepts of aromaticity. In addition, the book elaborates the various reactions such as substitution, free radical, addition, elimination and alkylation reactions. Finally, the text presents a detailed discussion on molecular rearrangements, oximes and diazo compounds, as well as the concepts of photochemistry. KEY FEATURES: Presents a number of examples to explain the mechanistic concepts. Offers graphs and tables at various places to illustrate the key points. Includes latest information on the subject.

Author : R.A. Abramovitch
Publisher : Springer Science & Business Media
Page : 609 pages
File Size : 52,8 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461331926

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Reactive Intermediates by R.A. Abramovitch Pdf

The field of reactive intermediates has been blossoming at a rapid rate in recent years and its impact on chemistry, both "pure" and "applied," as well as on biology, astronomy, and other areas of science, is enormous. Several books have been published which cover the area; one, edited by McManus, * surveys the subject in general at the senior undergraduate or beginning graduate level. In addition, a number of monographs have appeared which deal with individual topics such as carbenes, nitrenes, free radicals, carbanions, carbenium ions, and so on, in great depth. Our objective is somewhat different. We hope that these Advances in . . . type of volumes will appear at irregular intervals of a year to 18 months each. We intend to publish up-to-date reviews in relatively new areas of the chemistry of reactive intermediates. These will be written by world authorities in the field, each one of whom will give the reader a current in-depth review of all aspects of the chemistry of each of these species. It is our plan that the subjects to be reviewed will cover not only organic chemistry but also inorganic, physical, bio-, industrial, and atmospheric chemistry. The volumes themselves, we hope, will end up being reasonably interdisciplinary, though this need not and probably will not be the case for the individual reviews.

Author : Francis A. Carey,Richard J. Sundberg
Publisher : Springer Science & Business Media
Page : 1199 pages
File Size : 55,5 Mb
Release : 2007-06-27
Category : Science
ISBN : 9780387448992

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Advanced Organic Chemistry by Francis A. Carey,Richard J. Sundberg Pdf

The two-part, fifth edition of Advanced Organic Chemistry has been substantially revised and reorganized for greater clarity. The material has been updated to reflect advances in the field since the previous edition, especially in computational chemistry. Part A covers fundamental structural topics and basic mechanistic types. It can stand-alone; together, with Part B: Reaction and Synthesis, the two volumes provide a comprehensive foundation for the study in organic chemistry. Companion websites provide digital models for study of structure, reaction and selectivity for students and exercise solutions for instructors.

Author : David Jollow
Publisher : Springer Science & Business Media
Page : 513 pages
File Size : 53,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461341246

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Biological Reactive Intermediates by David Jollow Pdf

The concept that detoxication is the inevitable result of biotransformation of xenobiotic compounds by mammalian systems has undergone modification since it was first described. Indeed, despite the fact that R. T. Williams popularized the notion, he was among the first to caution that it was not possible to predict the biological activities of the resulting metabolites. It has become increasingly apparent in recent years that not only do many metabolites of drugs and other chemicals display biological activity but also in many instances these metabolites play an important role in initiating several forms of cancer and are the cause of a variety of types of toxicity. Thus it seems appropriate to collect in one volume a series of reports outlining advances in the study of the formation of chemically active intermediary metabolic products of chemicals, mechanisms of toxicity or carcinogenesis, and pathways for true detoxication of these chemicals. The work of R. T. Williams, beginning in the late 1920s and early 1930s, marked the first concerted effort to understand the biotransformation of foreign chemicals in animals. He investigated the metabolic pathway of numerous compounds in a wide variety of animal species while training large numbers of our colleagues who have been responsible for further advances in biochemistry, pharmacology, and toxicology. Another pioneer in the study of drug metabo lism, B. B.