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Recent Advances in the Biology of Alcoholism by Charles S. Lieber,Barry Stimmel Pdf
This valuable book, written by eminent researchers, focuses on the exciting developments in the field of alcohol metabolism and alcohol-endocrine interactions. They contribute significantly to our understanding of the metabolism of ethanol and its effects on the body with comprehensive chapters on the heterogeneity of aldehyde dehydrogenase, alcohol-drug interactions, the pathogenesis of alcoholic liver disease, and more.
The Genetics of Alcoholism by Henri Begleiter,Benjamin Kissin Pdf
This volume provides an in-depth look at the genetic influences that contribute to the development of alcoholism. Part I: Epidemiologic Studies contains five chapters that examine the various approaches employed in the study of the genetics of alcoholism. It provides a historical perspectiveand details all the essentials of this subject. Part II: Selective Breeding Studies highlights the results of research involving the selective breeding of rodents. This type of research has produced homogenous strains exhibiting specific behavioral responses considered significant in thedevelopment and maintenance of alcohol dependence. The studies presented in Part III: Phenotypic Studies investigate and analyze phenotypic markers that serve as correlates to the genotypic determinants of alcoholism. Through its broad scope, this volume provides for the first time a panoramic viewof the knowledge available on the hereditary influences of alcoholism.
Behavioral Neurobiology of Alcohol Addiction by Wolfgang Sommer,Rainer Spanagel Pdf
The question how alcohol alters mood states and why this may end up becoming an addiction is puzzling alcohol researchers since decades. In this volume, an assembly of highly distinguished experts and leaders in alcohol addiction research provides lucid presentations of the current knowledge and research challenges as well as interesting viewpoints on future research directions aimed to stimulate communication and convergence between clinical and preclinical researchers, and to renew interest in the vibrant field of alcohol addiction research among a wide scientifically minded audience. Five Current Topics are discussed in this volume: Neurobiological mechanisms of alcoholism, Genetics, Clinical phenotypes and their preclinical models, Brain imaging, and Translational approaches for treatment development, both pharmacological and non-pharmacological. These areas have in our opinion brought alcohol research substantially forward and influenced our thinking about how to reach our common paramount goal, namely to offer effective treatment solutions for an extensive group of patients with largely unmet medical needs.
The previous volume, The Pathogenesis of Alcoholism: Psychosocial Factors, attempted to describe the interaction of biological, psychological, and social factors that lead to the initiation and perpetuation of alcoholism. The preface to that volume presented our particular view of the bio-. psycho-social interaction as a progressive process in which earlier developments produce new pathogenetic mechanisms, which in turn lead to still other cyclical feedback activities. Although influences from each of the three phenomenologic levels are at work during each stage of the clinical course, it would appear that social factors are most significant in the early phase, psychological factors at the intermediate level, and biological ones toward the end. These differences are only relative, however, for influences of all three types surely are operative during all stages of the syndrome. This appears to be particularly true for the biological parameters of activity. Don Goodwin (1976), who has supplied much of the data that support the role of hereditary factors in alcoholism, is wont to say that all living behavior is biological-by definition. The operational evidence for this is perhaps more evident in alcoholism than in other syndromes. For example, the general social indifference of many Asians to alcohol may reflect the presence of an atypical isoenzyme of alcohol dehydrogenase rather than some independently derived cultural norm.
Alcohol and Alcoholism by John H. Hannigan,Linda P. Spear,Norman E. Spear,Charles R. Goodlett Pdf
Recent years have seen more systematic investigations of the consequences of prenatal and early postnatal exposure to alcohol for brain and behavioral development. Offers an overview of what they have shown, and points out directions for further research
Recent Developments in Alcoholism by Marc Galanter Pdf
From the President of the American Society of Addiction Medicine Recent Developments in Alcoholism (Volume 10) is a major contribution to the literature of addiction medicine. This volume, 'ru.cohol and Cocaine: Similarities and Differences," contains an impressive collection of chapters from the basic research, epidemiological, and clinical research perspectives, as well as articles that address the relative policy issues and clinical application and patient care concerns. It also sends a message to those who would still distinguish between alcohol and drugs, or legal and illegal drugs. In the research laboratory, in the intentions and behavior of the user, and by the clinician, such distinctions have never been upheld. The first section, "Clinical Pathology," includes chapters on the role of alcohol in cocaine dependence, dual-diagnosis empirical and developmental humanistic approaches, and on neuroendocrine and catecholamine levels in humans during administration and withdrawal of cocaine and alcohol, emer gency room evaluation of cocaine-associated neuropsychiatric disorders, and clinical and pharmacological interactions of alcohol and cocaine. These chap ters, written by authors who are preeminent in their fields, offer a broad perspective to both the researcher and the clinician on relevant issues in clinical pathology. .
The American Psychiatric Association Practice Guideline for the Pharmacological Treatment of Patients With Alcohol Use Disorder by American Psychiatric Association Pdf
The guideline focuses specifically on evidence-based pharmacological treatments for AUD in outpatient settings and includes additional information on assessment and treatment planning, which are an integral part of using pharmacotherapy to treat AUD.
An intriguing look at the history of alcoholism and its dramatic effects, from the first fermented grape to current advances in genetic research. Alcoholism tells the story of a disease familiar to many yet not well understood. It is the first "biography" of alcohol abuse that gauges its devastating effects on the body, the family, the economy, and the community. Alcoholism provides the latest understanding of the disease as a behavioral dysfunction and a biological condition. Coverage includes the origins of alcohol and the discovery of alcoholism as a medical disease; the biology of alcoholism and its effects on the body; and current diagnostic and treatment methods for alcoholism. In addition, the book explores the effects on society of such alcoholism-related problems as domestic abuse, fetal alcohol syndrome, drunk driving, and suicide, as well as promising new directions in alcoholism research, awareness, treatment, and prevention.
Psychological Theories of Drinking and Alcoholism by Kenneth E. Leonard,Howard T. Blane Pdf
Updating and expanding the classic Psychological Theories of Drinking and Alcoholism, this fully revised second edition incorporates state-of-the-art presentations from leaders in the alcoholism field. Contributors review established and emerging approaches that guide research into the psychological processes influencing drinking and alcoholism. The volume's multidisciplinary approach also takes into account biological, pharmacological, and social factors, offering important insights into the development and escalation of drinking problems and the various approaches to treatment. Including significantly expanded coverage of developmental, social learning, and cognitive theories, the book features new chapters on genetics, neurobiology, and emotions.
Author : World Health Organization Publisher : World Health Organization Page : 472 pages File Size : 50,9 Mb Release : 2019-02-14 Category : Medical ISBN : 9789241565639
Global Status Report on Alcohol and Health 2018 by World Health Organization Pdf
The report provides an overview of alcohol consumption and harms in relation to the UN Sustainable Development Goals (Chapter 1) presents global strategies action plans and monitoring frameworks (Chapter 2) gives detailed information on: the consumption of alcohol in populations (Chapter 3); the health consequences of alcohol consumption (Chapter 4); and policy responses at national level (Chapter 5). In its final chapter 6 the imperative for reducing harmful use of alcohol in a public health perspective is presented. In addition the report contains country profiles for WHO Member States and appendices with statistical annexes a description of the data sources and methods used to produce the estimates and references.
Through the vivid, true stories of five people who journeyed into and out of addiction, a renowned neuroscientist explains why the “disease model” of addiction is wrong and illuminates the path to recovery. The psychiatric establishment and rehab industry in the Western world have branded addiction a brain disease, based on evidence that brains change with drug use. But in The Biology of Desire, cognitive neuroscientist and former addict Marc Lewis makes a convincing case that addiction is not a disease, and shows why the disease model has become an obstacle to healing. Lewis reveals addiction as an unintended consequence of the brain doing what it’s supposed to do—seek pleasure and relief—in a world that’s not cooperating. Brains are designed to restructure themselves with normal learning and development, but this process is accelerated in addiction when highly attractive rewards are pursued repeatedly. Lewis shows why treatment based on the disease model so often fails, and how treatment can be retooled to achieve lasting recovery, given the realities of brain plasticity. Combining intimate human stories with clearly rendered scientific explanation, The Biology of Desire is enlightening and optimistic reading for anyone who has wrestled with addiction either personally or professionally.
Heavy Drinking informs the general public for the first time how recent research has discredited almost every widely held belief about alcoholism, including the very concept of alcoholism as a single disease with a unique cause. Herbert Fingarette presents constructive approaches to heavy drinking, including new methods of helping heavy drinkers and social policies for preventing heavy drinking and the harms associated with it.
Critical Issues in Alcohol and Drugs of Abuse Testing by Amitava Dasgupta Pdf
Critical Issues in Alcohol and Drugs of Abuse Testing, Second Edition, addresses the general principles and technological advances for measuring drugs and alcohol, along with the pitfalls of drugs of abuse testing. Many designer drugs, for example, are not routinely tested in drugs of abuse panels and may go undetected in a drug test. This updated edition is a must-have for clinical pathologists, toxicologists, clinicians, and medical review officers and regulators, bridging the gap between technical and clinical information. Topics of note include the monitoring of pain management drugs, bath salts, spices (synthetic marijuana), designer drugs and date rape drugs, and more. Serves as a ready resource of information for alcohol and drug testing Ideal resource for making decisions related to the monitoring and interpretation of results Includes concise content for clinical laboratory scientists, toxicologists and clinicians