Recent Advances In Therapeutic Drug Monitoring And Clinical Toxicology

Author : Seth Kwabena Amponsah,Yashwant V. Pathak
Publisher : Springer Nature
Page : 384 pages
File Size : 49,9 Mb
Release : 2022-10-25
Category : Medical
ISBN : 9783031123986

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Recent Advances in Therapeutic Drug Monitoring and Clinical Toxicology by Seth Kwabena Amponsah,Yashwant V. Pathak Pdf

This book gives an overview of therapeutic drug monitoring (TDM) and its clinical application. It also highlights recent advances in toxicological studies, as they relate to therapeutic drug monitoring. This is one of the few books available on the market that covers TDM. Therapeutic drug monitoring (TDM) is a clinical decision-making tool that enables dosage regimen adjustments based on clinical and laboratory measurements. TDM not only involves the measuring of drug concentrations but also interpretation of the results. There is a strong correlation between drug concentrations in body fluids and outcome than between dose and outcome. The chapters include coverage of analytical techniques, pharmacokinetics, therapeutic indices, artificial intelligence and recent advances in toxicological studies. The book fills a gap in published literature and provides reliable information on; Analytical techniques in TDM and clinical toxicology TDM and pharmacokinetic studies TDM of drugs with narrow therapeutic indices Artificial intelligence in TDM and clinical toxicology Future directions and challenges

Author : Irving Sunshine
Publisher : CRC Press
Page : 807 pages
File Size : 51,7 Mb
Release : 2023-06-14
Category : Medical
ISBN : 9781000943030

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Recent Developments in Therapeutic Drug Monitoring and Clinical Toxicology by Irving Sunshine Pdf

Papers from the Second International Conference on TDM Toxicology (date and place not stated) describe research on various aspects of therapeutic monitoring pharmacology, selected high-performance liquid chromatographic methods, antiepileptics, substances subject to abuse, inorganics. Over 100 contr

Author : Irving Sunshine
Publisher : CRC Press
Page : 806 pages
File Size : 41,6 Mb
Release : 1992-02-21
Category : Medical
ISBN : 082478586X

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Recent Developments in Therapeutic Drug Monitoring and Clinical Toxicology by Irving Sunshine Pdf

Papers from the Second International Conference on TDM Toxicology (date and place not stated) describe research on various aspects of therapeutic monitoring pharmacology, selected high-performance liquid chromatographic methods, antiepileptics, substances subject to abuse, inorganics. Over 100 contr

Author : Steven H.Y. Wong
Publisher : Routledge
Page : 521 pages
File Size : 52,6 Mb
Release : 2017-09-19
Category : Medical
ISBN : 9781351408479

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Therapeutic Drug Monitoring and Toxicology by Liquid Chromatography by Steven H.Y. Wong Pdf

This important, new reference provides the first , up-to-date, and comprehensive treatmentof the various liquid chromatography (LC) instrumentation for Therapeutic DrugMonitoring (TDM) and toxicology drug assays and reviews the clinical pharmacologyof major classes of drugs and their LC analyses.Written by authoritative contributors who bring many years of personal laboratory/clinical experience to the book, this interdisciplinary work : presents the principlesof TDM, sampling techniques, and various instrumentation topics, including computerinterfacing, mass spectrometry, fluorescence , electrochemical detection, and bloodcollection devices . .. examines six primary classes of drugs, complete with recommendedLC procedures and emphasizing recently introduced drugs and their LC analyses. .. and documents medicolegal guidelines and laboratory management considerations,providing a contemporary assessment of today's laboratory needs.The only practical, current guide available on the subject, Therapeutic Drug Monitoringand Toxicology by Li([uid Chromatography belongs in the personal libraries of clinicaland analytical chemists and biochemists, clinical pharmacologists, clinical toxicologists,clinical pathologists, immunologists, liquid chromatographers, mass spectroscopists, laboratorydirectors, laboratory instrument manufacturers , and medical technologists. Thebook is also vital supplementary reading for advanced undergraduate and graduate-levelclinical chemistry, toxicology, clinical pathology, and liquid chromatography course.

Author : Miao Yan,Yao Liu,Jennifer Martin
Publisher : Frontiers Media SA
Page : 282 pages
File Size : 42,9 Mb
Release : 2022-10-26
Category : Medical
ISBN : 9782832501085

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Therapeutic Drug Monitoring and Clinical Toxicology of Anti-Cancer Drugs by Miao Yan,Yao Liu,Jennifer Martin Pdf

Author : Miao Yan,Yao Liu,Jennifer Martin
Publisher : Frontiers Media SA
Page : 136 pages
File Size : 51,7 Mb
Release : 2023-04-04
Category : Science
ISBN : 9782832519752

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Therapeutic drug monitoring and clinical toxicology of anti-cancer drugs, volume II by Miao Yan,Yao Liu,Jennifer Martin Pdf

Author : Irving Sunshine
Publisher : CRC Press
Page : 806 pages
File Size : 47,5 Mb
Release : 2019-10-07
Category : Drug monitoring
ISBN : 0367402831

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Recent Developments in Therapeutic Drug Monitoring and Clinical Toxicology by Irving Sunshine Pdf

Papers from the Second International Conference on TDM Toxicology (date and place not stated) describe research on various aspects of therapeutic monitoring pharmacology, selected high-performance liquid chromatographic methods, antiepileptics, substances subject to abuse, inorganics. Over 100 contr

Author : Steven H.Y. Wong,Irving Sunshine
Publisher : CRC Press
Page : 370 pages
File Size : 47,9 Mb
Release : 1996-12-20
Category : Medical
ISBN : 0849326486

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Handbook of Analytical Therapeutic Drug Monitoring and Toxicology by Steven H.Y. Wong,Irving Sunshine Pdf

Adapting modern advances in analytical techniques to daily laboratory practices challenges many toxicologists, clinical laboratories, and pharmaceutical scientists. The Handbook of Analytical Therapeutic Drug Monitoring and Toxicology helps you keep abreast of the innovative changes that can make your laboratory - and the studies undertaken in it - a success. This volume simplifies your search for appropriate techniques, describes recent contributions from leading investigators, and provides valuable evaluations and advice. Discover how to use non-invasively obtained specimens to your best advantage The text features alternative biological specimens such as hair, meconium, saliva, sweat, and vitreous humor, which are not extensively used because they require more sensitive procedures than other biological specimens. How to overcome these limitations is a major topic of the handbook. Experts describe basic principles of innovative techniques and detail how they can be adapted to analyzing alternative biological specimens. The evaluations of the pros and cons of various advances in immunodiagnostics and how they apply to analytes will help you determine their suitability to your own laboratory. The Handbook of Analytical Therapeutic Drug Monitoring and Toxicology helps you make the most of innovative procedures that will open the doors to productive laboratory practices.

Author : Leslie M. Shaw
Publisher : Unknown
Page : 145 pages
File Size : 44,7 Mb
Release : 1993
Category : Electronic
ISBN : OCLC:165166870

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Proceedings of the Third International Congress of Therapeutic Drug Monitoring and Clinical Toxicology by Leslie M. Shaw Pdf

Author : Mike Hallworth,Nigel Capps
Publisher : AACC Press
Page : 0 pages
File Size : 47,7 Mb
Release : 1993
Category : Biochemistry
ISBN : 0902429051

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Therapeutic Drug Monitoring and Clinical Biochemistry by Mike Hallworth,Nigel Capps Pdf

This text considers the close inter-relationship of therapeutic drug monitoring and clinical biochemistry. It covers principles of TDM, looking at drug dosage and effect; clinical monitoring and pharmacokinetics; interpretation and response; and near-patient testing. It also includes information on methodology, dosage prediction, drug structure, sampling requirements and target range. The drugs covered include anti-convulsants; aminoglycosides; lithium; anti-arrythmics; xanthines; cyclosporine; methotrexate; and tricyclics. The work also contains case studies.

Author : Amitava Dasgupta
Publisher : Academic Press
Page : 469 pages
File Size : 55,8 Mb
Release : 2012-06-07
Category : Medical
ISBN : 9780123854681

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Therapeutic Drug Monitoring by Amitava Dasgupta Pdf

Therapeutic Drug Monitoring: Newer Drugs and Biomarkers features timely topics such as the monitoring of classical and newer drugs, pharmacogenomics and the application of biomarkers in therapeutic drug monitoring. This reference also discusses the limitations of current commercially available immunoassays for therapeutic monitoring. It presents new and sophisticated techniques used for proper determination of blood levels and the clinical utility of therapeutic drug monitoring of contemporary drugs. Written by leading international experts and geared toward clinical pathologists, toxicologists, clinical chemists, laboratory professionals and physicians, this book is an essential resource on the current practice of therapeutic drug monitoring in improving patient safety. Includes both the technical and clinical issues associated with therapeutic drug monitoring Discusses the utility of therapeutic drug monitoring of newer drugs such as antiretroviral agents, anticonvulsants, antidepressants etc. Provides up-to-date information on issues in pharmacogenomics and personalized medicine with emphasis on therapy with warfarin, certain anticancer drugs and antidepressants Covers important content on the limitations of commercially available immunoassays (chemical tests) for therapeutic drug monitoring and additional analytical techniques

Author : Benjamin Gerson
Publisher : Unknown
Page : 231 pages
File Size : 52,5 Mb
Release : 1987
Category : Electronic
ISBN : OCLC:643032666

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Therapeutic drug monitoring by Benjamin Gerson Pdf

Author : Amitava Dasgupta
Publisher : CRC Press
Page : 475 pages
File Size : 42,6 Mb
Release : 2017-06-16
Category : Electronic
ISBN : 1138111716

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Advances in Chromatographic Techniques for Therapeutic Drug Monitoring by Amitava Dasgupta Pdf

For drugs with a narrow therapeutic index, therapeutic drug monitoring methods are essential for patient management. Although immunoassays are commercially available for many drugs and most laboratories use these assays for routine therapeutic monitoring, they have many limitations which hinder their efficacy. Providing practical guidelines for implementing preferred gas and liquid chromatographic methods, Advances in Chromatographic Techniques for Therapeutic Drug Monitoring is a comprehensive reference describing the theory and application of therapeutic drug monitoring in clinical laboratories. Edited by a distinguished authority in the field and containing contributions from a variety of experts, the book discusses preanalytical variables, the pitfalls of immunoassays, tandem mass spectrometry, issues related to pain management and herbal supplements, and therapeutic drug monitoring for a range of medications, including: Anticonvulsants Digitalis Cardioactive drugs Antidepressants Immunosuppressants Anti-cancer drugs Vancomycin and aminoglycosides Antibiotics Antiretroviral drugs Nonnarcotic analgesics Anti-inflammatory drugs ? Examing older and newer drugs, the book contains detailed discussions on the rationale for therapeutic drug monitoring of each class of drugs, along with their basic pharmacology and toxicology. An extensive list of references is provided at the end of each chapter so that those interested in implementing a new drug assay can find the most appropriate method for the intended drug.

Author : Amitava Dasgupta,Matthew Krasowski
Publisher : Academic Press
Page : 382 pages
File Size : 43,9 Mb
Release : 2019-09-14
Category : Science
ISBN : 9780128158500

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Therapeutic Drug Monitoring Data by Amitava Dasgupta,Matthew Krasowski Pdf

Therapeutic Drug Monitoring Data: A Concise Guide, Fourth Edition serves as a ready resource of information on commonly monitored drugs that will help readers make decisions relating to the monitoring and interpretation of results. It is an easy-to-read source of information on intended use, pharmacokinetics, therapeutic range, and toxic concentrations, as well as bioavailability, disposition, metabolism and the excretion of commonly monitored therapeutic drugs. This fully updated fourth edition includes sections on new anticonvulsants, anti-depressant and anti-HIV drugs, new drugs for advanced cancer treatment, and thoroughly updated chapters that address new pitfalls and problems in the lab. Serves as a ready resource of information for commonly monitored drugs Presents a useful, quick guide for those making decisions related to monitoring and interpretation of results Provides concise, easily digestible content for clinical laboratory scientists, toxicologists and clinicians

Author : Institute of Medicine,Board on Health Sciences Policy,Committee on Accelerating Rare Diseases Research and Orphan Product Development
Publisher : National Academies Press
Page : 442 pages
File Size : 42,5 Mb
Release : 2011-04-03
Category : Medical
ISBN : 9780309158060

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Rare Diseases and Orphan Products by Institute of Medicine,Board on Health Sciences Policy,Committee on Accelerating Rare Diseases Research and Orphan Product Development Pdf

Rare diseases collectively affect millions of Americans of all ages, but developing drugs and medical devices to prevent, diagnose, and treat these conditions is challenging. The Institute of Medicine (IOM) recommends implementing an integrated national strategy to promote rare diseases research and product development.