Recent Developments In Graves Ophthalmopathy

Author : Mark F. Prummel
Publisher : Springer Science & Business Media
Page : 195 pages
File Size : 50,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461546474

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Recent Developments in Graves’ Ophthalmopathy by Mark F. Prummel Pdf

Recent Developments in Graves' Ophthalmopathy offers an overview of the pathogenesis, assessment and management of patients with thyroid-associated eye disease. Each chapter is written by an expert and truly represents the current state of the art on the particular topic. This book can therefore almost be considered a textbook on this enigmatic disorder. Recent Developments in Graves' Ophthalmopathy is designed for all those interested in this disease, including basic scientists, clinical endocrinologists, ophthalmologists, radiotherapists, and orbital surgeons. The book gives a comprehensive overview of all aspects of Graves' ophthalmopathy. Subjects covered include the pathology of Graves' eye disease and the controversial views on its autoimmune pathogenesis; assessment of the eye changes using reliable measurements; medical management of Graves' eye disease with an overview of the many treatment options available to the clinician, including orbital radiotherapy and other immunosuppressive treatments; management of the thyroid disease; and finally, the techniques for performing various surgical procedures, which are explained and illustrated.

Author : Wilmar M. Wiersinga,George Kahaly
Publisher : Karger Medical and Scientific Publishers
Page : 275 pages
File Size : 47,6 Mb
Release : 2007
Category : Medical
ISBN : 9783805583428

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Graves' Orbitopathy by Wilmar M. Wiersinga,George Kahaly Pdf

In recent years, close interdisciplinary cooperation of numerous international experts, both clinicians and basic scientists, within the European Group of Graves' orbitopathy (EUGOGO) has yielded much valuable progress and new information, which this publication brings together. Subjects covered include the pathology of Graves' orbitopathy (GO) and the controversial views on its pathogenesis; assessment of changes using reliable measuring techniques; medical management of GO including established and alternative treatment options; technical explanations and illustrations of various surgical procedures and finally, the molecular, immunologic, and clinical aspects of this complex disorder. Stressing the current management of thyroid eye disease, this book offers medical practitioners a thorough overview of associated changes in the eyes of patients with GO. Therefore, this publication is an essential resource for ophthalmologists, internists, endocrinologists, pediatricians, immunologists, specialists in nuclear medicine, neuroradiologists and radiotherapists, specialists in laboratory medicine and pathology, otorhinolaryngologists, orbital and neurosurgeons as well as oral and maxillofacial surgeons.

Author : W.M. Wiersinga,G.J. Kahaly
Publisher : Karger Medical and Scientific Publishers
Page : 300 pages
File Size : 41,7 Mb
Release : 2010-08-17
Category : Medical
ISBN : 9783805595322

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Graves' Orbitopathy by W.M. Wiersinga,G.J. Kahaly Pdf

The significant progress in the understanding of the pathogenesis and the treatment of Graves’ orbitopathy (GO) has warranted a second edition of this book within three years of the first. Now also fully incorporated is the EUGOGO consensus statement on management of GO, which since has been accepted worldwide as a useful guideline. Furthermore all chapters have been thoroughly updated. Subjects covered include the pathology of GO and the controversial views on its pathogenesis; assessment of changes using reliable measuring techniques; medical management of GO including established and alternative treatment options; technical explanations and illustrations of various surgical procedures and finally, the molecular, immunologic, and clinical aspects of this complex disorder. Two new chapters have been added: one describing the socioeconomic impact of the disease and the other outlining the Amsterdam Declaration on Graves’ Orbitopathy. The successful question-and-answer format facilitates its use as a reference guide for medical practitioners and surgeons working in the fields of ophthalmology, internal medicine, endocrinology, pediatrics, immunology, as well as otorhinolaryngology.

Author : Wilmar M. Wiersinga,George Kahaly
Publisher : Karger Medical and Scientific Publishers
Page : 300 pages
File Size : 43,6 Mb
Release : 2010-01-01
Category : Medical
ISBN : 9783805595315

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Graves' Orbitopathy by Wilmar M. Wiersinga,George Kahaly Pdf

The significant progress in the understanding of the pathogenesis and the treatment of Graves' orbitopathy (GO) has warranted a second edition of this book within three years of the first. Now also fully incorporated is the EUGOGO consensus statement on management of GO, which since has been accepted worldwide as a useful guideline. Furthermore all chapters have been thoroughly updated. Subjects covered include the pathology of GO and the controversial views on its pathogenesis; assessment of changes using reliable measuring techniques; medical management of GO including established and alternative treatment options; technical explanations and illustrations of various surgical procedures and finally, the molecular, immunologic, and clinical aspects of this complex disorder. Two new chapters have been added: one describing the socioeconomic impact of the disease and the other outlining the Amsterdam Declaration on Graves' Orbitopathy. The successful question-and-answer format facilitates its use as a reference guide for medical practitioners and surgeons working in the fields of ophthalmology, internal medicine, endocrinology, pediatrics, immunology, as well as otorhinolaryngology.

Author : A. Pinchera
Publisher : Springer Science & Business Media
Page : 579 pages
File Size : 43,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461309451

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Thyroid Autoimmunity by A. Pinchera Pdf

In 1956, three groups independently reported evidence that some thyroid disease appearing spontaneously in humans or experimentally induced in animals are related to autoimmune processes. The interval between these landmark discoveries and the present has witnessed a remarkable and continuing growth of both knowledge and concepts concerning the mechanisms of immune regulation, the pathogenesis of autoimmune thyroid diseases, and their clinical and laboratory manifestations. More importantly knowledge of thyroid autoimmunity has, in many respects, comprised the vanguard of an ever increasing appreciation and understanding of autoimmune diseases in general. On November 24-26 1986, an International Symposium on Thyroid Autoimmunity was held in Pisa. Its purpose was to commemorate the birth of thyroid autoimmunity as a scientific discipline, to summarize current knowledge and concepts in this area, and where possible, to anticipate areas of opportunity for the future - hence the theme of the Symposium, Memories and Perspectives. To open the meeting, the Magnifico Rettore (Chancellor) of the University of Pisa granted special Awards to Dr. Deborah Doniach, Dr. Ivan Roitt, and Dr. Noel R. Rose, who published the first fundamental studies in the field of thyroid autoimmunity, and to Dr. Duncan G. Adams, whose discovery of the long-acting thyroid stimulator (LATS) opened the door to our current understanding of the pathogenesis of Graves' disease. During the meeting thirty plenary lectures were presented.

Author : C. Renate Pickardt,Klaus Peter Boergen
Publisher : S Karger Ag
Page : 0 pages
File Size : 47,6 Mb
Release : 1989
Category : Medical
ISBN : 3805550405

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Graves' Ophthalmopathy by C. Renate Pickardt,Klaus Peter Boergen Pdf

Author : John A.H. Wass,Paul M. Stewart
Publisher : Oxford University Press, USA
Page : 2158 pages
File Size : 45,7 Mb
Release : 2011-07-28
Category : Medical
ISBN : 9780199235292

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Oxford Textbook of Endocrinology and Diabetes by John A.H. Wass,Paul M. Stewart Pdf

Now in its second edition, the Oxford Textbook of Endocrinology and Diabetes is a fully comprehensive, evidence-based, and highly-valued reference work combining basic science with clinical guidance, and providing first rate advice on diagnosis and treatment.

Author : Raymond S. Douglas,Allison N. McCoy,Shivani Gupta
Publisher : Springer
Page : 157 pages
File Size : 42,8 Mb
Release : 2014-11-27
Category : Medical
ISBN : 9781493917464

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Thyroid Eye Disease by Raymond S. Douglas,Allison N. McCoy,Shivani Gupta Pdf

This book offers ophthalmologists and medical practitioners a concise, data-driven review of the information that is most relevant in guiding the diagnosis and management of thyroid-associated eye diseases (TED). Thyroid-Associated Eye Disease can be read in its entirety to give a perspective of the field, but also considered as a reference as clinical questions arise. The goal is to deliver data- driven guidance and discreet approaches and suggestions useful for clinical practice and decision making. Advances in diagnostic evaluation, including autoantibody assessment, are reviewed, and the diagnostic features of euthyroid TED are also discussed. All relevant aspects of treatment are covered, from the use of radioactive iodine, long-term medical therapy, and surgical thyroidectomy through to the treatment of active TED by steroids and novel biologics and the role of minimally invasive surgery. Numerous supporting images are included, and helpful checklists will aid the practitioner in treatment decision making.

Author : Edgar Harrison
Publisher : Foster Academics
Page : 0 pages
File Size : 42,9 Mb
Release : 2023-09-26
Category : Medical
ISBN : 1646465490

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Thyroid Eye Disease: Understanding Graves' Ophthalmopathy by Edgar Harrison Pdf

Graves' disease refers to a disorder affecting the immune system which leads to the overproduction of thyroid hormones. Graves' ophthalmopathy, also called Graves' orbitopathy, is an autoimmune disease affecting the retro-ocular tissues in patients having Graves' disease. It is primarily the disease of the orbit and can have severe implications, such as loss of sight. It causes swelling in the area around the eyes, which causes bulging of the eyes. The symptoms of Graves' ophthalmopathy include double vision, bulging eyes, swelling in the eyelids, vision loss, sensitivity to light, redness or inflammation, and difficulty in moving eyes. This disease results in increased extraocular muscle volume and orbital fat in the orbital space. The targets of autoimmune attack within Graves' ophthalmopathy are the fibroblasts residing in the orbital tissues. Radiation, immunosuppression and surgical procedures, like orbital decompression surgery, eye muscle surgery and eyelid surgery are utilized to treat severe forms of this disease. This book contains some path-breaking studies on Graves' Ophthalmopathy. It is a valuable compilation of topics, ranging from the basic to the most complex advancements in the study of this disease. The book will serve as a reference to a broad spectrum of readers.

Author : Rebecca S. Bahn
Publisher : Springer
Page : 344 pages
File Size : 45,6 Mb
Release : 2015-03-31
Category : Medical
ISBN : 9781493925346

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Graves' Disease by Rebecca S. Bahn Pdf

This indispensable volume is designed to facilitate the best possible physician–patient discussion on Graves’ disease by providing the most up-to-date evidence-based information in a clinically useful and patient-centric manner. Comprehensive and covering such topics as Professionalism and the Art of Patient-centric Thyroidology, the Immunopathogenesis of Graves’ Disease, and the Diagnosis and Management of Thyroid Storm, the book addresses all the important refinements in the treatment of Graves’ disease in recent years. These include new indications and contraindications for antithyroid drugs, improved approaches to radioactive iodine therapy, the development of novel surgical techniques, and a better understanding of the combined use of these modalities, among other developments. Also addressed are the advances in the treatment of GO, including the use of disease activity and severity assessments to inform management decisions and the completion of the first randomized controlled therapeutic trials. Developed by a renowned group of internationally respected authorities, Graves’ Disease: A Comprehensive Guide for Clinicians is a significant new reference that will be of great interest to all clinicians who treat this debilitating condition.

Author : Markus Luster,Leonidas H. Duntas,Leonard Wartofsky
Publisher : Springer
Page : 770 pages
File Size : 50,6 Mb
Release : 2019-01-08
Category : Medical
ISBN : 9783319721026

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The Thyroid and Its Diseases by Markus Luster,Leonidas H. Duntas,Leonard Wartofsky Pdf

This book is an up-to-date and comprehensive guide to all the common thyroid disorders that may be seen by internists, endocrinologists, nuclear medicine physicians, and endocrine surgeons. While the fundamentals of thyroid hormone function and regulation in health and disease are well covered, the primary focus is on the clinical approach to thyroid disease, with detailed coverage of both initial diagnosis and management and the role of imaging. Because most endocrine diseases are chronic and lifelong, special emphasis is placed on long-term management and the common pitfalls that may be encountered by the clinician. The editors are internationally acknowledged leaders in the field of thyroid disease and have gathered an outstanding team of authors, all of whom are also highly expert in their respective areas, but who, equally importantly, write in a clear and lucid style. The numerous isotope scan and ultrasonographic images ensure that the book will serve as a valuable reference atlas to which the physician will return again and again.

Author : Elaine A Moore
Publisher : Unknown
Page : 128 pages
File Size : 44,6 Mb
Release : 2007-02-22
Category : Electronic
ISBN : 9781412215336

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Thyroid Eye Disease by Elaine A Moore Pdf

The only educational resource and guide for patients with Graves' Ophthalmopathy, an inflammatory eye disorder that often precedes, accompanies, or follows autoimmune thyroid disease.

Author : Basil Rapoport,Sandra M. McLachlan
Publisher : Springer Science & Business Media
Page : 307 pages
File Size : 42,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461544074

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Graves’ Disease by Basil Rapoport,Sandra M. McLachlan Pdf

From the perspective of the investigator, Graves' disease is a fascinating disorder with unique features and opportunities for study. The discovery in 1956 that Graves' disease was caused by a humoral factor, later shown to be an antibody to the TSH receptor, was a triumph for modern investigative medicine. Rapid progress is now being made in (i) understanding the molecular interaction between autoantibodies and the TSH receptor, (ii) identifying the genes that contribute to the predisposition to disease, (iii) developing an animal model of Graves' disease, and (iv) identifying the long-sought orbital antigen in ophthalmopathy. From the clinical standpoint, although Graves' disease is eminently treatable, there is no definitive cure. None of the therapeutic options are ideal. It is hoped that rapid progress in understanding the pathogenesis of the disease will lead to the ultimate goal of some form of immunotherapy that will make antithyroid drugs, radioiodine and thyroidectomy obsolete. The chapters in Graves' Disease: Pathogenesis and Treatment represent the viewpoints of many prominent clinicians and investigators working in the field. The editors are grateful for their contributions which cover an unusually comprehensive compendium of subjects relating to the disease.

Author : Fredric E. Wondisford,Sally Radovick
Publisher : Elsevier Health Sciences
Page : 435 pages
File Size : 40,6 Mb
Release : 2009-06-26
Category : Medical
ISBN : 9781437719697

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Clinical Management of Thyroid Disease E-Book by Fredric E. Wondisford,Sally Radovick Pdf

Clinical Management of Thyroid Disease is an exciting new book edited by Fredric Wondisford, MD—developer of the revolutionary new drug, Thyrotropin—and Sally Radovick, MD, with contributions from experts in the field. It fulfills the niche of a succinct, clinical resource to help you translate research into practice. This full-color volume offers valuable information on thyroid cancer and non-cancerous lesions, the effect of drugs on thyroid function, genetic disorders, and more in an accessible, easy-to-read consistent format. Presents the expertise of authors and editorial staff comprised of leaders in the field of thyroid research and clinical management for the best-qualified guidance on diagnosis and treatment. Provides a full-color, comprehensive approach that makes valuable information easy to locate and quick to read. Covers relevant topics applicable to all levels of training and expertise to serve as a detailed clinical reference on everything from the basic to the sophisticated. Captures research advances on hot topics such as thyroid cancer and non-cancerous lesions, the effect of drugs on thyroid function, and genetic disorders so that you can incorporate them into the way you treat patients.

Author : Gonzalo Díaz-Soto
Publisher : BoD – Books on Demand
Page : 282 pages
File Size : 46,6 Mb
Release : 2014-05-21
Category : Medical
ISBN : 9789535113843

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Thyroid Disorders by Gonzalo Díaz-Soto Pdf

The thyroid disorders are one of the most common and exciting areas of endocrinology. Hypothyroidism, multinodular goiter, hyperthyroidism and thyroid cancer are only few of the several implications that the thyroid disorders have in health. In fact, thyroid hormones regulate not only metabolism process, but also many other molecular and physiological systems. From this point of view, hyperthyroidism complications are a good example of the significance of thyroid hormone actions. This book aims to provide a general view of thyroid disorders, and a deeper explanation of hyperthyroidism and its complications and impact in health.