Recombinant Human Erythropoietin Rhepo In Clinical Oncology

Author : Mohammad Resa Nowrousian
Publisher : Springer Science & Business Media
Page : 502 pages
File Size : 44,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783709176580

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Recombinant Human Erythropoietin (rhEPO) in Clinical Oncology by Mohammad Resa Nowrousian Pdf

Anemia is a frequent complication of cancer and its treatment. A number of clinical studies shows that the impact of anemia is much greater than previously thought. Beyond clinical symptoms, anemia significantly impairs physical and metabolic functions as well as patients' activity, well-being and quality of life. Life expectancy is also affected. In this book, written by a group of outstanding international experts, the current knowledge on anemia in cancer and its treatment with rhEPO is presented. Future developments are also discussed. Based on a broad spectrum of topics, the book describes the scientific and clinical aspects of anemia in various fields of oncology and gives diagnostic and therapeutic recommendations on when and how to use rhEPO.

Author : Carsten Nieder,Luka Milas,Kie-Kian Ang
Publisher : Springer Science & Business Media
Page : 284 pages
File Size : 45,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642556135

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Modification of Radiation Response by Carsten Nieder,Luka Milas,Kie-Kian Ang Pdf

This book describes and summarizes the radiation responses of both normal and neoplastic tissues with a focus on rational strategies for the modification of these responses. Emerging data from molecular oncology and radiobiology are reviewed in depth. The book covers not only general principles of radiation-induced reactions but also a large number of preclinical and clinical data that will guide the reader through this complex and dynamic field and will provide valuable information for the development of further research projects.

Author : Steven G. Elliott,MaryAnn Foote,Graham Molineux
Publisher : Springer Science & Business Media
Page : 337 pages
File Size : 43,6 Mb
Release : 2009-06-05
Category : Medical
ISBN : 9783764386986

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Erythropoietins, Erythropoietic Factors, and Erythropoiesis by Steven G. Elliott,MaryAnn Foote,Graham Molineux Pdf

A comprehensive one-source guide to the most current information on red blood cell formation and the action of recombinant human erythropoietins. Topics covered include: erythropoiesis, recombinant protein discovery and production, and treatment of patients with anemia. The newest theories in erythropoiesis (receptors, signaling), manufacturing, new formulations, and clinical research are discussed. The text is ideal for researchers and clinical investigators in academia, biotechnology, and pharmaceutical companies, as well as clinical research associates, clinical monitors, and physician investigators.

Author : Felix Kratz,Peter Senter,Henning Steinhagen
Publisher : John Wiley & Sons
Page : 1828 pages
File Size : 53,8 Mb
Release : 2013-09-30
Category : Medical
ISBN : 9783527647750

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Drug Delivery in Oncology by Felix Kratz,Peter Senter,Henning Steinhagen Pdf

In this first authoritative overview on modern cancer chemotherapy 121 international specialists have contributed their experience and recent data for what is likely to become the gold standard in the field. The authors summarize knowledge gained over the past decade, from basic concepts to successful applications in the clinic, covering active and passive targeting strategies as well as tissue-specific approaches. All current and future targeted delivery systems are discussed, from ligand-based to antibody-based polymer-based systems, right up to micro- and nanoparticulate systems. A special section covers the delivery of nucleic acid therapeutics, such as siRNA, miRNA and antisense nucleotides. In each case, a description of the basic technique is followed by a discussion of the latest preclinical and clinical developments in the field. By virtue of its clear and didactic structure, rich illustrative material and summary chapters, this handbook and ready reference enables the efficient transfer of knowledge between different disciplines, from basic research to the clinician and vice versa. It is equally well suited for professionals, researchers and students in medical oncology and cancer biology, and is also excellent for teaching medical students the foundations of 21st century cancer chemotherapy.

Author : Clemens Fritsch,Thomas Ruzicka
Publisher : Springer Science & Business Media
Page : 128 pages
File Size : 46,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783709160466

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Fluorescence Diagnosis and Photodynamic Therapy of Skin Diseases by Clemens Fritsch,Thomas Ruzicka Pdf

This book is the most up-to-date publication on fluorescence diagnostic (FDAP) and photodynamic therapy (PDT) methods used in dermatology. Both techniques are presently world wide introduced as standards for the delineation and the treatment of cutaneous precancerous stages and tumors, which show steadily increasing numbers due to e.g. more frequent sun exposure. Summarizing experiences on more than 5.000 treated patients, it offers a comprehensive information on every aspect of skin tumor detection and treatment. The main part of the book focuses on the clinical aspects giving detailed descriptions on skin tumor detection as well as photodynamic treatment of selected diseases (solar keratoses, basal cell carcinomas, squamous cell carcinomas, Bowen's disease, psoriasis lesions, etc.). The clinically oriented chapters are supplemented by practical guidelines for PDT and FDAP. The included atlas is comprised of 270 high quality color figures allowing daily use as a handbook.

Author : Eugen Plas,H. Pflüger,U. Maier,W.A. Hübner
Publisher : Springer Science & Business Media
Page : 174 pages
File Size : 46,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783709106310

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The Aging Bladder by Eugen Plas,H. Pflüger,U. Maier,W.A. Hübner Pdf

Aging is associated with morphologic and functional alterations of organ systems including the genitourinary tract. Aging of the bladder leads to urgency, frequency, dysuria, recurrent urinary tract infections and incontinence both in aging men and women. These symptoms occur frequently, are very distressing and influence daily life of the aging person. Medication and incontinence devices are a tremendous financial burden on health care systems. This book reviews present knowledge of morphologic and functional alterations of the aging bladder both in men and women, adding new insights in order to optimize therapeutic options for treatment.

Author : Ines Mader,Patrizia R. Fürst-Weger,Robert M. Mader,Elisabeth Nogler-Semenitz,Sabine Wassertheurer
Publisher : Springer Science & Business Media
Page : 401 pages
File Size : 40,7 Mb
Release : 2009-12-02
Category : Medical
ISBN : 9783211888933

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Extravasation of Cytotoxic Agents by Ines Mader,Patrizia R. Fürst-Weger,Robert M. Mader,Elisabeth Nogler-Semenitz,Sabine Wassertheurer Pdf

The extravasation of cytotoxic agents can result in severe local tissue damage and medical emergencies during tumour therapy. This revised compendium is intended to help clinicians assess any situation speedily and with certainty. The general section of the book includes topics such as predisposition, prevention, type of harm, general measures in handling extravasated drugs, specific antidotes, and documentation. In the 2nd edition, the scientific information contained in the general section and relating to the actual substances has been updated. The substance specific part of the book includes detailed instructions on handling more than 50 cytotoxic drugs, to initiate targeted measures. Templates for an extravasation set, overview tables, documentation sheets, and patient information, as we as a CD-ROM are included to support clinical practice. The book is the outcome of a consensus of an interdisciplinary working group that has collected and systematically reviewed all published literature on the topic.

Author : Michael Molls,Peter Vaupel,Carsten Nieder,Mitchell Steven Anscher
Publisher : Springer Science & Business Media
Page : 363 pages
File Size : 53,5 Mb
Release : 2009-03-25
Category : Medical
ISBN : 9783540743866

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The Impact of Tumor Biology on Cancer Treatment and Multidisciplinary Strategies by Michael Molls,Peter Vaupel,Carsten Nieder,Mitchell Steven Anscher Pdf

Te rapidly changing concepts in radiation oncology with the development of more precise - strumentation for delivery of radiation therapy and a greater emphasis on hypofractionation technologies require a very intimate knowledge of tumor biology and the infuence of various biologic factors on dose distribution within the tumor in terms of homogeneity as well as prev- tion of any late efects on normal tissue surrounding the tumor itself. Not only are these major factors in clinical practice but also the known factors of inhomogeneity of cancer cells, the impact of microenvironment in terms of radiation efect, and host factors make it mandatory to design therapeutic strategies to improve the outcome and to diminish any potential short-term or lo- term risks from the radiation therapy. Te authors have developed an outstanding text that deals with these strategies and how they would impact on established and emerging new technologies and treatment. Te context of the presentations within a multidisciplinary combined modality therapy program is incredibly - portant. In this volume, various topics are reviewed including tumor genesis, cell proliferation, - giogenesis, the physiologic characteristics of malignant tissues, invasion and adhesion, the route and role pursued in the development of metastasis, and the role of the human immune system in cancer prevention and development.

Author : Joseph C. LaManna,Michelle A. Puchowicz,Kui Xu,David K. Harrison,Duane F. Bruley
Publisher : Springer Science & Business Media
Page : 374 pages
File Size : 54,6 Mb
Release : 2011-03-29
Category : Medical
ISBN : 9781441977564

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Oxygen Transport to Tissue XXXII by Joseph C. LaManna,Michelle A. Puchowicz,Kui Xu,David K. Harrison,Duane F. Bruley Pdf

This book covers all aspects of oxygen delivery to tissue, including blood flow and its regulation as well as oxygen metabolism. Special attention will be paid to methods of oxygen measurement in living tissue and application of these technologies to understanding physiological and biochemical basis for pathology related to tissue oxygenation. This book is multidisciplinary and designed to bring together experts and students from a range of research fields including biochemical engineering, physiology, microcirculation, and hematology.

Author : Horst Pagel,Christoph Weiss,Wolfgang Jelkmann
Publisher : Springer Science & Business Media
Page : 318 pages
File Size : 51,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642770746

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Pathophysiology and Pharmacology of Erythropoietin by Horst Pagel,Christoph Weiss,Wolfgang Jelkmann Pdf

The book contains a series of about 40 articles reflecting the state-of-the-art of the topic "Pathophysiology and Pharmacology of Erythropoietin". Results from both basic research and clinical studies are described in detail. The papers show that the possible therapeutic spectrum of erythropoietin could be expanded considerably when compared with the present situation.

Author : Anonim
Publisher : Elsevier
Page : 867 pages
File Size : 48,5 Mb
Release : 2004-05-10
Category : Science
ISBN : 9780080497198

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Oxygen Sensing by Anonim Pdf

The ability of cells to sense and respond to changes in oxygenation underlies a multitude of developmental, physiological, and pathological processes. This volume provides a comprehensive compendium of experimental approaches to the study of oxygen sensing in 48 chapters that are written by leaders in their fields.

Author : Santwana Padhi,Anindita Behera,Eric Lichtfouse
Publisher : Springer Nature
Page : 515 pages
File Size : 43,6 Mb
Release : 2022-11-14
Category : Medical
ISBN : 9783031148484

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Polymeric nanoparticles for the treatment of solid tumors by Santwana Padhi,Anindita Behera,Eric Lichtfouse Pdf

This book focuses on the emerging research in the field of treatment of solid tumors or cancer with new drug delivery systems using nanotechnology. Nanotechnology has given us a good scope for development of new innovative drug delivery strategies to increase the therapeutic efficacy of anticancer drugs with reduced off-target side effects. Cancer is one of the main causes of death worldwide due to the limitations of classical therapies such as low solubility of active drugs, toxic side effects on healthy cells and resistance of tumor cells. These issues are partly solved by the recent development of polymeric nanoparticles, which improve drug absorption and the therapeutic index, while reducing side effects. Drug carriers must be biocompatible, biodegradable and non-immunogenic. Coupled to a ligand that has affinity for that particular cell, polymeric nanoparticles are used to target specifically malignant cells or tissues and, in turn, improve drug stability. This book presents the latest advances in the application of polymeric particles for cancer treatment, with focus on the tumor microenvironment, synthesis, active and passive targeting, patents, targeting over-expressed receptors, tumor-targeting ligands, theranostics, glioblastoma tumors, lung cancer, breast cancer, prostate cancer and pH-responsive nanoparticles

Author : Graham Molineux,Mary A. Foote,Steven Elliott
Publisher : Springer Science & Business Media
Page : 270 pages
File Size : 44,5 Mb
Release : 2006-03-08
Category : Medical
ISBN : 9783764375430

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Erythropoietins and Erythropoiesis by Graham Molineux,Mary A. Foote,Steven Elliott Pdf

A comprehensive one-source guide to the most current information on red blood cell formation and the action of recombinant human erythropoietins. Topics covered include: erythropoiesis, recombinant protein discovery and production, and treatment of patients with anemia. The newest theories in erythropoiesis (receptors, signaling), manufacturing, new formulations, and clinical research are discussed. The text is ideal for researchers and clinical investigators in academia, biotechnology, and pharmaceutical companies, as well as clinical research associates, clinical monitors, and physician investigators. This softcover volume is an unchanged second printing of the hardcover edition published in 2003.

Author : Tamotsu Miyazaki,M. Asaka,Manabu Musashi
Publisher : Unknown
Page : 164 pages
File Size : 53,8 Mb
Release : 1996
Category : Bone marrow
ISBN : UOM:39015037448092

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Clinical Oncology Today by Tamotsu Miyazaki,M. Asaka,Manabu Musashi Pdf

Author : Mohd Rushdan Md Noor,Tay Eng Hseon,Low Jen Hui Jeffrey
Publisher : CRC Press
Page : 842 pages
File Size : 51,9 Mb
Release : 2014-06-18
Category : Medical
ISBN : 9789814463065

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Gynaecologic Cancer by Mohd Rushdan Md Noor,Tay Eng Hseon,Low Jen Hui Jeffrey Pdf

Gynaecologic oncology is one of the most important subjects in gynaecology and a very challenging field. The management of patients with gynaecological cancers is complex, as the impact of the outcome of such cancers can be critical. This handbook covers the basics of carcinogenesis and the advances in the prevention and management of all gynaecologic cancers, including breast cancer. Gynaecologic oncology has always been perceived as the most difficult subject in obstetrics and gynaecology, but this handbook proves it otherwise. The text is presented in a systematic and easy-to-understand manner and is supplemented by plenty of images and illustrations and up-to-date references from established sources. The book also introduces readers to the new FIGO 2009 staging system and will be a very useful reference for researchers and clinicians.