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Author : Douglas MacN. Surgenor
Publisher : Unknown
Page : 128 pages
File Size : 48,8 Mb
Release : 1974
Category : Erythrocytes
ISBN : 0126772509
Author : Laura Dean
Publisher : Unknown
Page : 128 pages
File Size : 46,6 Mb
Release : 2005
Category : Blood group antigens
ISBN : OCLC:225053075
Author : Oguz Baskurt,Björn Neu,Herbert J. Meiselman
Publisher : CRC Press
Page : 326 pages
File Size : 40,6 Mb
Release : 2011-09-28
Category : Medical
ISBN : 9781439841808
Red blood cells in humans—and most other mammals—have a tendency to form aggregates with a characteristic face-to-face morphology, similar to a stack of coins. Known as rouleaux, these aggregates are a normally occurring phenomenon and have a major impact on blood rheology. What is the underlying mechanism that produces this pattern? Does this really happen in blood circulation? And do these rouleaux formations have a useful function? The first book to offer a comprehensive review of the subject, Red Blood Cell Aggregation tackles these and other questions related to red blood cell (RBC) aggregates. The book covers basic, clinical, and physiological aspects of this important biophysical phenomenon and integrates these areas with concepts in bioengineering. It brings together state-of-the-art research on the determinants, mechanisms, and measurement and effects of RBC aggregation as well as on variations and comparative aspects. After an introductory overview, the book outlines factors and conditions that affect RBC aggregation. It presents the two hypotheses—the bridging model and the depletion model—that provide potential mechanisms for the adhesive forces that lead to the regular packing of the cells in rouleaux formations. The book also reviews the methods used to quantify RBC aggregation in vitro, focusing on their importance in clinical practice. Chapters discuss the effect of RBC aggregation on the in vitro rheology of blood as well as on tube flow. The book also looks at what happens in the circulation when red blood cells aggregate and examines variations due to physiological and pathophysiological challenges. The concluding chapter explores the formation of red blood cell aggregates in other mammals. Written by leading researchers in the field, this is an invaluable resource for basic science, medical, and clinical researchers; graduate students; and clinicians interested in mammalian red blood cells.
Author : Douglas Surgenor
Publisher : Elsevier
Page : 629 pages
File Size : 52,7 Mb
Release : 2012-12-02
Category : Medical
ISBN : 9780323161480
The Red Blood Cell, Second Edition, Volume I provides information pertinent to red blood cells, which is the most intensely studied human tissue. This book reviews the basic biomedical knowledge about the circulating, red blood cells. Organized into 13 chapters, this edition starts with an overview of the discovery of red blood cells, which results in the growth of knowledge in the areas of clinical disease and therapeutic efforts. This book then discusses the significant functions of the red blood cells, which exists basically to transport the respiratory gases. Other chapters examine the red blood cell’s capacity for protein synthesis and its ability to diversify its function. This book discusses as well the progress in the structural analysis of lipids. The final chapter deals with the capacity to store red blood cells frozen for long periods with high yield of viable physiological functional cells after post-thaw processing. Scientists, physicians, teachers, researchers, and students will find this book extremely useful.
Author : Roland N. Pittman
Publisher : Biota Publishing
Page : 117 pages
File Size : 41,7 Mb
Release : 2016-08-18
Category : Medical
ISBN : 9781615047215
This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
Author : Mikko Nikinmaa
Publisher : Springer Science & Business Media
Page : 273 pages
File Size : 45,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642839092
This book reviews the respiratory function of vertebrate red cells. I have defined the phrase "respiratory function" broadly to include, in addition to the actual oxygen and carbon dioxide transport, erythropoiesis, haemoglobin synthesis, red cell structure, the deformability of red cells in circulation, ion and substrate transport across the cell membrane, cellular metabolism, and control of cellular volume and pH. All of these aspects of the red cell function may affect gas transport between the respiratory epithelia and the tissues. Throughout the book, I have tried to relate our current knowledge about the nucleated red cell function to the wealth of information about the function of mammalian red cells. However, whenever possible, I have placed the emphasis on the nucleated red cell function for two reasons. First, the erythro cytes of 90% of vertebrate species are nucleated, and, second, nucleated red cell function has not been reviewed earlier in a single volume. This being the case, I have tried to make the reference list as complete as I could with regard to nucleated red cells. I hope that the approach adopted is useful for both com parative and human physiologists. Many people have contributed to the making of this book directly or in directly. Antti Soivio started me in this field. Prof. Henrik Wallgren has always encouraged fresh scientific ideas in his department. My present ideas of red cell function have been influenced by work carried out with Prof. Roy E.
Author : Toby L. Simon,Jeffrey McCullough,Edward L. Snyder,Bjarte G. Solheim,Ronald G. Strauss
Publisher : John Wiley & Sons
Page : 754 pages
File Size : 46,6 Mb
Release : 2016-05-23
Category : Medical
ISBN : 9781119012993
Rossi's Principles of Transfusion Medicine is the most comprehensive and practical reference on transfusion science and medicine available Led by a world class Editor team, including two past-presidents of AABB, a past- President of the American Board of Pathology and members of the FDA Blood Products Advisory Committee , and international contributor team Comprehensive reference resource, considered the gold standard in transfusion Covers current hot topics such as donor care – including the frequency of donation and management of iron deficiency/status), patient blood management, hemovigilance, cstem cell therapies, and global aspects of the organization of transfusion and transplant services New material on molecular immunohematology Companion website includes figures, full text and references
Author : Timm Krüger
Publisher : Springer Science & Business Media
Page : 169 pages
File Size : 51,8 Mb
Release : 2012-10-02
Category : Science
ISBN : 9783834823762
The rheology of dense red blood cell suspensions is investigated via computer simulations based on the lattice Boltzmann, the immersed boundary, and the finite element methods. The red blood cells are treated as extended and deformable particles immersed in the ambient fluid. In the first part of the work, the numerical model and strategies for stress evaluation are discussed. In the second part, the behavior of the suspensions in simple shear flow is studied for different volume fractions, particle deformabilities, and shear rates. Shear thinning behavior is recovered. The existence of a shear-induced transition from a tumbling to a tank-treading motion is demonstrated. The transition can be parameterized by a single quantity, namely the effective capillary number. It is the ratio of the suspension stress and the characteristic particle membrane stress. At the transition point, a strong increase in the orientational order of the red blood cells and a significant decrease of the particle diffusivity are observed. However, the average cell deformation shows no signature of the transition.
Author : Henry Kenneth Walker,Wilbur Dallas Hall,John Willis Hurst
Publisher : Butterworth-Heinemann
Page : 1128 pages
File Size : 53,9 Mb
Release : 1990
Category : Medical
ISBN : MINN:31951D00416688Z
A guide to the techniques and analysis of clinical data. Each of the seventeen sections begins with a drawing and biographical sketch of a seminal contributor to the discipline. After an introduction and historical survey of clinical methods, the next fifteen sections are organized by body system. Each contains clinical data items from the history, physical examination, and laboratory investigations that are generally included in a comprehensive patient evaluation. Annotation copyrighted by Book News, Inc., Portland, OR
Author : O. C. Gruner
Publisher : Butterworth-Heinemann
Page : 408 pages
File Size : 50,8 Mb
Release : 2013-10-02
Category : Science
ISBN : 9781483194691
The Biology of the Blood-Cells presents a critical review of relationships between changes in the blood-forming organs and the blood picture. The book discusses the minute morphology of various blood-cells; the fundamental basis of hemopoiesis of human; and the purpose of the bone marrow as a red-cell factory. Some of the topics covered in the text are the structures of lymphocytes; the production and functions of neutrophile leucocyte; and the chemical characters of cells. The description of megakaryocyte; the proliferation of cells in the bone marrow; and the metaplastic and allied changes in the bone-marrow are also covered. The book further discusses the development of erythroblast cells; the characteristics of erythrocytes; and the description of reticular substance. The text then looks into the changes in the hemoglobin content and the comparative morphology of the red cells. A chapter is devoted to the metaplastic, metahyperplastic, and aplastic phenomena of erythropoiesis. The book can provide useful information to hematologists, doctors, students, and researchers.
Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 52,9 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181
Author : Yoshihito Yawata
Publisher : John Wiley & Sons
Page : 454 pages
File Size : 51,7 Mb
Release : 2006-01-24
Category : Science
ISBN : 9783527605323
This publication presents the structure and function of biological membranes to improve the understanding of cells in both normal and pathogenic states. Recently, vast amounts of new information have been accumulated, especially about pathological conditions, and there is now much evidence correlating genotypes and phenotypes in normal and disease states. This book surveys the most recent findings in research on the molecular biology, biochemistry, and genetics of the membranes of human red blood cells.
Author : Ingolf Bernhardt,J. Clive Ellory
Publisher : Springer Science & Business Media
Page : 761 pages
File Size : 42,6 Mb
Release : 2013-04-17
Category : Science
ISBN : 9783662051818
51 worldwide leading experts in the field of erythrocyte research contributed to this first book on transport processes in red blood cells. It explains the latest findings on the basis of well-established principles, in an accessibly structured and carefully organized compilation.
Author : Lars Kaestner,Anna Bogdanova
Publisher : Frontiers E-books
Page : 118 pages
File Size : 45,6 Mb
Release : 2014-12-03
Category : Biology (General)
ISBN : 9782889193486
Human red blood cells are formed mainly in the bone marrow and are believed to have an average life span of approximately 120 days. However, is it true for all red blood cells? What are the changes associated with red cell maturation, adulthood and senescence? What are the determinants of red cell life span and clearance? What are the mechanisms in control of red cell mass in healthy humans and patients with various forms of anemia? What are the markers of circulating red cell senescence and in cells during storage and transfusion? Within the life span may properties of red cells change leading to age-mixed circulating cell populations. Although these cells appear to be genetically terminated by the time they are released into the blood stream, they undergo surprisingly versatile modifications depending on the life-style and health conditions of a “human host”. Numerous disorders are believed to be associated with facilitated ageing of red blood cells. “In vitro ageing” and damage of red blood cells during storage is yet one more important issue related to the risks and efficiency of blood transfusion. Many of the mechanisms behind such effects are far from being fully understood. In this context the Research Topic is set to include articles in the field of biochemical investigations, biophysical approaches, physiological and clinical studies related to red blood cell maturation and aging. This includes Original Research, Methods, Hypothesis and Theory, Reviews and Perspectives.
Author : Barbara J. Bain
Publisher : John Wiley & Sons
Page : 489 pages
File Size : 49,6 Mb
Release : 2008-04-15
Category : Medical
ISBN : 9781405171601
Blood Cells has been written with both the practisinghaematologist and the trainee in mind. It aims to provide a guidefor use in the diagnostic haematology laboratory, covering methodsof collection of blood specimens, blood film preparation andstaining, the principles of manual and automated blood counts andthe assessment of the morphological features of blood cells. Thepractising haematologist should find this book sufficientlycomprehensive to be a reference source while, at the same time, thetrainee haematologist and biomedical scientist should find it astraightforward and practical bench manual. Enables both the haematologist and laboratory scientist toidentify blood cell features, from the most common to the moreobscure Provides essential information on methods of collection, bloodfilm preparation and staining, together with the principles ofmanual and automated blood counts Completely revised and updated, incorporating much newlypublished information: now includes advice on further tests when aspecific diagnosis is suspected Four hundred high quality photographs to aid with blood cellidentification Highlights the purpose and clinical relevance of haematologylaboratory tests throughout