Regenerative Engineering And Developmental Biology

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Regenerative Engineering and Developmental Biology

David M. Gardiner
Regenerative Engineering and Developmental Biology Book PDF

Author : David M. Gardiner
Publisher : CRC Press
Page : 498 pages
File Size : 50,5 Mb
Release : 2017-08-21
Category : Medical
ISBN : 9781351646499

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Regenerative Engineering and Developmental Biology by David M. Gardiner Pdf

Regenerative Engineering and Developmental Biology: Principles and Applications examines cutting-edge developments in the field of regenerative engineering. Specific attention is given to activities that embrace the importance of integrating developmental biology and tissue engineering, and how this can move beyond repairing damage to body parts to instead regenerate tissues and organs. The text furthermore focusses on the five legs of the field of regenerative engineering, including: materials, developmental biology, stem cells, physics, and clinical translation. This book was written by leading developmental biologists; each chapter examines the processes that these biologists study and how they can be advanced by using the tools available in tissue engineering/biomaterials. Individual chapters are complete with concluding remarks and thoughts on the future of regenerative engineering. A list of references is also provided to aid the reader with further research. Ultimately, this book achieves two goals. The first encourages the biomedical community to think about how inducing regeneration is an engineering problem. The second goal highlights the discoveries with animal regeneration and how these processes can be engineered to regenerate body parts. Regenerative Engineering and Developmental Biology: Principles and Applications was written with undergraduate and graduate-level biomedical engineering students and biomedical professionals in mind.

Regenerative Engineering and Developmental Biology

David M. Gardiner
Regenerative Engineering and Developmental Biology Book PDF

Author : David M. Gardiner
Publisher : Unknown
Page : 634 pages
File Size : 53,7 Mb
Release : 2017
Category : HEALTH & FITNESS
ISBN : 1315120186

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Regenerative Engineering and Developmental Biology by David M. Gardiner Pdf

"This cutting-edge comprehensive reference work details the technologies related to cell structure in the regeneration of tissue and organs. The focus of the first few chapters is related to what cells do (proliferation, migration, and differentiation/dedifferentiation), leading to the production of a population of regeneration-competent cells. The book then covers the information that tells cells where to go and what to make. This is the regeneration blueprint that tells the cells how to remake patterns and restore functions."--Provided by publisher.

Stem Cells & Regenerative Medicine

Krishnarao Appasani,Raghu K. Appasani
Stem Cells Regenerative Medicine Book PDF

Author : Krishnarao Appasani,Raghu K. Appasani
Publisher : Springer Science & Business Media
Page : 629 pages
File Size : 50,8 Mb
Release : 2010-11-01
Category : Science
ISBN : 9781607618607

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Stem Cells & Regenerative Medicine by Krishnarao Appasani,Raghu K. Appasani Pdf

Defined as, “The science about the development of an embryo from the fertilization of the ovum to the fetus stage,” embryology has been a mainstay at universities throughout the world for many years. Throughout the last century, embryology became overshadowed by experimental-based genetics and cell biology, transforming the field into developmental biology, which replaced embryology in Biology departments in many universities. Major contributions in this young century in the fields of molecular biology, biochemistry and genomics were integrated with both embryology and developmental biology to provide an understanding of the molecular portrait of a “development cell.” That new integrated approach is known as stem-cell biology; it is an understanding of the embryology and development together at the molecular level using engineering, imaging and cell culture principles, and it is at the heart of this seminal book. Stem Cells and Regenerative Medicine: From Molecular Embryology to Tissue Engineering is completely devoted to the basic developmental, cellular and molecular biological aspects of stem cells as well as their clinical applications in tissue engineering and regenerative medicine. It focuses on the basic biology of embryonic and cancer cells plus their key involvement in self-renewal, muscle repair, epigenetic processes, and therapeutic applications. In addition, it covers other key relevant topics such as nuclear reprogramming induced pluripotency and stem cell culture techniques using novel biomaterials. A thorough introduction to stem-cell biology, this reference is aimed at graduate students, post-docs, and professors as well as executives and scientists in biotech and pharmaceutical companies.

Developmental Biology and Musculoskeletal Tissue Engineering

Martin J. Stoddart,April M. Craft,Girish Pattappa,Oliver F.W. Gardner
Developmental Biology and Musculoskeletal Tissue Engineering Book PDF

Author : Martin J. Stoddart,April M. Craft,Girish Pattappa,Oliver F.W. Gardner
Publisher : Academic Press
Page : 270 pages
File Size : 55,8 Mb
Release : 2018-04-24
Category : Science
ISBN : 9780128115381

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Developmental Biology and Musculoskeletal Tissue Engineering by Martin J. Stoddart,April M. Craft,Girish Pattappa,Oliver F.W. Gardner Pdf

Developmental Biology and Musculoskeletal Tissue Engineering: Principles and Applications focuses on the regeneration of orthopedic tissue, drawing upon expertise from developmental biologists specializing in orthopedic tissues and tissue engineers who have used and applied developmental biology approaches. Musculoskeletal tissues have an inherently poor repair capacity, and thus biologically-based treatments that can recapitulate the native tissue properties are desirable. Cell- and tissue-based therapies are gaining ground, but basic principles still need to be addressed to ensure successful development of clinical treatments. Written as a source of information for practitioners and those with a nascent interest, it provides background information and state-of-the-art solutions and technologies. Recent developments in orthopedic tissue engineering have sought to recapitulate developmental processes for tissue repair and regeneration, and such developmental-biology based approaches are also likely to be extremely amenable for use with more primitive stem cells. Brings the fields of tissue engineering and developmental biology together to explore the potential for regenerative medicine-based research to contribute to enhanced clinical outcomes Initial chapters provide an outline of the development of the musculoskeletal system in general, and later chapters focus on specific tissues Addresses the effect of mechanical forces on the musculoskeletal system during development and the relevance of these processes to tissue engineering Discusses the role of genes in the development of musculoskeletal tissues and their potential use in tissue engineering Describes how developmental biology is being used to influence and guide tissue engineering approaches for cartilage, bone, disc, and tendon repair

Regenerative Engineering

Yusuf Khan,Cato T. Laurencin
Regenerative Engineering Book PDF

Author : Yusuf Khan,Cato T. Laurencin
Publisher : CRC Press
Page : 154 pages
File Size : 41,7 Mb
Release : 2018-04-19
Category : Medical
ISBN : 9781498738255

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Regenerative Engineering by Yusuf Khan,Cato T. Laurencin Pdf

This book focuses on advances made in both materials science and scaffold development techniques, paying close attention to the latest and state-of-the-art research. Chapters delve into a sweeping variety of specific materials categories, from composite materials to bioactive ceramics, exploring how these materials are specifically designed for regenerative engineering applications. Also included are unique chapters on biologically-derived scaffolding, along with 3D printing technology for regenerative engineering. Features: Covers the latest developments in advanced materials for regenerative engineering and medicine. Each chapter is written by world class researchers in various aspects of this medical technology. Provides unique coverage of biologically derived scaffolding. Includes separate chapter on how 3D printing technology is related to regenerative engineering. Includes extensive references at the end of each chapter to enhance further study.

3D Bioprinting in Regenerative Engineering

Ali Khademhosseini,Gulden Camci-Unal
3D Bioprinting in Regenerative Engineering Book PDF

Author : Ali Khademhosseini,Gulden Camci-Unal
Publisher : CRC Press
Page : 300 pages
File Size : 49,8 Mb
Release : 2018-04-17
Category : Technology & Engineering
ISBN : 9781315280479

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3D Bioprinting in Regenerative Engineering by Ali Khademhosseini,Gulden Camci-Unal Pdf

Regenerative engineering is the convergence of developmental biology, stem cell science and engineering, materials science, and clinical translation to provide tissue patches or constructs for diseased or damaged organs. Various methods have been introduced to create tissue constructs with clinically relevant dimensions. Among such methods, 3D bioprinting provides the versatility, speed and control over location and dimensions of the deposited structures. Three-dimensional bioprinting has leveraged the momentum in printing and tissue engineering technologies and has emerged as a versatile method of fabricating tissue blocks and patches. The flexibility of the system lies in the fact that numerous biomaterials encapsulated with living cells can be printed. This book contains an extensive collection of papers by world-renowned experts in 3D bioprinting. In addition to providing entry-level knowledge about bioprinting, the authors delve into the latest advances in this technology. Furthermore, details are included about the different technologies used in bioprinting. In addition to the equipment for bioprinting, the book also describes the different biomaterials and cells used in these approaches. This text: Presents the principles and applications of bioprinting Discusses bioinks for 3D printing Explores applications of extrusion bioprinting, including past, present, and future challenges Includes discussion on 4D Bioprinting in terms of mechanisms and applications

Organ Regeneration Based on Developmental Biology

Takashi Tsuji
Organ Regeneration Based on Developmental Biology Book PDF

Author : Takashi Tsuji
Publisher : Springer
Page : 257 pages
File Size : 43,9 Mb
Release : 2017-03-30
Category : Science
ISBN : 9789811037689

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Organ Regeneration Based on Developmental Biology by Takashi Tsuji Pdf

This book reviews three-dimensional (3D) stem cell culture and proof of concept for organ regeneration. The chapters present studies based on developmental biology but not tissue engineering using bio-degradative scaffolds. The ultimate goal of regenerative therapy, the next generation of regenerative therapy, is to develop fully functioning bioengineered 3D organs that can replace lost or damaged organs following disease, injury, or aging. Next-generation regenerative therapy will consist of organ-replacement regenerative therapy, which aims to reproduce reciprocal epithelial and epithelial interactions and epithelial and mesenchymal interactions that occur during embryogenesis. The book then discusses the generation of several 3D functional organs and organoids such as brain, inner ear, tooth, hair, salivary glands, lacrimal glands, gastrointestinal organs, kidney, liver, and lung. This work will appeal to a wide readership such as medical scientists, developmental biologists, clinicians, and patients. The volume provides valuable information and ideas to form a next-generation field of science.

Exploring Sources of Variability Related to the Clinical Translation of Regenerative Engineering Products

National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Forum on Regenerative Medicine
Exploring Sources of Variability Related to the Clinical Translation of Regenerative Engineering Products Book PDF

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Forum on Regenerative Medicine
Publisher : National Academies Press
Page : 133 pages
File Size : 40,9 Mb
Release : 2019-07-19
Category : Medical
ISBN : 9780309489096

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Exploring Sources of Variability Related to the Clinical Translation of Regenerative Engineering Products by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Forum on Regenerative Medicine Pdf

The emerging multidisciplinary field of regenerative engineering is devoted to the repair, regeneration, and replacement of damaged tissues or organs in the body. To accomplish this it uses a combination of principles and technologies from disciplines such as advanced materials science, developmental and stem cell biology, immunology, physics, and clinical translation. The term "regenerative engineering" reflects a new understanding of the use of tissue engineering for regeneration and also the growing number of research and product development efforts that incorporate elements from a variety of fields. Because regenerative engineered therapies rely on live cells and scaffolds, there are inherent challenges in quality control arising from variability in source and final products. Furthermore, each patient recipient, tissue donor, and product application is unique, meaning that the field faces complexities in the development of safe and effective new products and therapies which are not faced by developers of more conventional therapies. Understanding the many sources of variability can help reduce this variability and ensure consistent results. The Forum on Regenerative Medicine hosted a public workshop on October 18, 2018, in Washington, DC, to explore the various factors that must be taken into account in order to develop successful regenerative engineering products. Invited speakers and participants discussed factors and sources of variability in the development and clinical application of regenerative engineering products, characteristics of high-quality products, and how different clinical needs, models, and contexts can inform the development of a product to improve patient outcomes. This publication summarizes the presentation and discussion of the workshop.

3D Bioprinting in Regenerative Engineering

Ali Khademhosseini,Gulden Camci-Unal
3D Bioprinting in Regenerative Engineering Book PDF

Author : Ali Khademhosseini,Gulden Camci-Unal
Publisher : CRC Press
Page : 385 pages
File Size : 54,9 Mb
Release : 2018-04-17
Category : Technology & Engineering
ISBN : 9781315280486

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3D Bioprinting in Regenerative Engineering by Ali Khademhosseini,Gulden Camci-Unal Pdf

Regenerative engineering is the convergence of developmental biology, stem cell science and engineering, materials science, and clinical translation to provide tissue patches or constructs for diseased or damaged organs. Various methods have been introduced to create tissue constructs with clinically relevant dimensions. Among such methods, 3D bioprinting provides the versatility, speed and control over location and dimensions of the deposited structures. Three-dimensional bioprinting has leveraged the momentum in printing and tissue engineering technologies and has emerged as a versatile method of fabricating tissue blocks and patches. The flexibility of the system lies in the fact that numerous biomaterials encapsulated with living cells can be printed. This book contains an extensive collection of papers by world-renowned experts in 3D bioprinting. In addition to providing entry-level knowledge about bioprinting, the authors delve into the latest advances in this technology. Furthermore, details are included about the different technologies used in bioprinting. In addition to the equipment for bioprinting, the book also describes the different biomaterials and cells used in these approaches. This text: Presents the principles and applications of bioprinting Discusses bioinks for 3D printing Explores applications of extrusion bioprinting, including past, present, and future challenges Includes discussion on 4D Bioprinting in terms of mechanisms and applications

Principles of Regenerative Medicine

Anthony Atala,Robert Lanza,Tony Mikos,Robert Nerem
Principles of Regenerative Medicine Book PDF

Author : Anthony Atala,Robert Lanza,Tony Mikos,Robert Nerem
Publisher : Academic Press
Page : 1454 pages
File Size : 40,5 Mb
Release : 2018-08-09
Category : Medical
ISBN : 9780128098936

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Principles of Regenerative Medicine by Anthony Atala,Robert Lanza,Tony Mikos,Robert Nerem Pdf

Principles of Regenerative Medicine, Third Edition, details the technologies and advances applied in recent years to strategies for healing and generating tissue. Contributions from a stellar cast of researchers cover the biological and molecular basis of regenerative medicine, highlighting stem cells, wound healing and cell and tissue development. Advances in cell and tissue therapy, including replacement of tissues and organs damaged by disease and previously untreatable conditions, such as diabetes, heart disease, liver disease and renal failure are also incorporated to provide a view to the future and framework for additional studies. Comprehensively covers the interdisciplinary field of regenerative medicine with contributions from leaders in tissue engineering, cell and developmental biology, biomaterials sciences, nanotechnology, physics, chemistry, bioengineering and surgery Includes new chapters devoted to iPS cells and other alternative sources for generating stem cells as written by the scientists who made the breakthroughs Edited by a world-renowned team to present a complete story of the development and promise of regenerative medicine

Innovations in Molecular Mechanisms and Tissue Engineering

Jeanne Wilson-Rawls,Kenro Kusumi
Innovations in Molecular Mechanisms and Tissue Engineering Book PDF

Author : Jeanne Wilson-Rawls,Kenro Kusumi
Publisher : Springer
Page : 182 pages
File Size : 47,6 Mb
Release : 2016-12-10
Category : Science
ISBN : 9783319449968

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Innovations in Molecular Mechanisms and Tissue Engineering by Jeanne Wilson-Rawls,Kenro Kusumi Pdf

This book marries stem cell biology, tissue engineering, and regenerative biology into a single, interdisciplinary volume. The chapters also explore embryonic stem cells, induced pluripotent stem cells, cardiovascular regeneration, skeletal development, inflammation, polymeric biomaterials, neural injury, cartilage regeneration, regeneration in ambystoma, models for regeneration using salamander and zebrafish, and more. The volume also discusses recent advances and their potential in developing future therapies. Innovations in Molecular Mechanisms and Tissue Engineering combines perspectives from the biomedical, bioengineering, and medical fields to present a cutting-edge, multifaceted picture of the tissue engineering and regenerative medicine fields. This installment of Springer’s Stem Cell Biology and Regenerative Medicine series is ideal for scientists, clinicians, and researchers in the fields of stem cell biology, regenerative medicine, biomedical engineering, and tissue engineering.

Stem Cells & Regenerative Medicine

Krishnarao Appasani,Raghu K. Appasani
Stem Cells Regenerative Medicine Book PDF

Author : Krishnarao Appasani,Raghu K. Appasani
Publisher : Humana Press
Page : 629 pages
File Size : 47,5 Mb
Release : 2011-07-21
Category : Science
ISBN : 1607618613

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Stem Cells & Regenerative Medicine by Krishnarao Appasani,Raghu K. Appasani Pdf

Defined as, “The science about the development of an embryo from the fertilization of the ovum to the fetus stage,” embryology has been a mainstay at universities throughout the world for many years. Throughout the last century, embryology became overshadowed by experimental-based genetics and cell biology, transforming the field into developmental biology, which replaced embryology in Biology departments in many universities. Major contributions in this young century in the fields of molecular biology, biochemistry and genomics were integrated with both embryology and developmental biology to provide an understanding of the molecular portrait of a “development cell.” That new integrated approach is known as stem-cell biology; it is an understanding of the embryology and development together at the molecular level using engineering, imaging and cell culture principles, and it is at the heart of this seminal book. Stem Cells and Regenerative Medicine: From Molecular Embryology to Tissue Engineering is completely devoted to the basic developmental, cellular and molecular biological aspects of stem cells as well as their clinical applications in tissue engineering and regenerative medicine. It focuses on the basic biology of embryonic and cancer cells plus their key involvement in self-renewal, muscle repair, epigenetic processes, and therapeutic applications. In addition, it covers other key relevant topics such as nuclear reprogramming induced pluripotency and stem cell culture techniques using novel biomaterials. A thorough introduction to stem-cell biology, this reference is aimed at graduate students, post-docs, and professors as well as executives and scientists in biotech and pharmaceutical companies.

Advances in Regenerative Medicine: Role of Nanotechnology, and Engineering Principles

Venkatram Prasad Shastri,George Altankov,Andreas Lendlein
Advances in Regenerative Medicine Role of Nanotechnology and Engineering Principles Book PDF

Author : Venkatram Prasad Shastri,George Altankov,Andreas Lendlein
Publisher : Springer Science & Business Media
Page : 414 pages
File Size : 40,5 Mb
Release : 2010-08-14
Category : Technology & Engineering
ISBN : 9789048187881

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Advances in Regenerative Medicine: Role of Nanotechnology, and Engineering Principles by Venkatram Prasad Shastri,George Altankov,Andreas Lendlein Pdf

This book summarizes the NATO Advanced Research Workshop (ARW) on “Nanoengineered Systems for Regenerative Medicine” that was organized under the auspices of the NATO Security through Science Program. I would like to thank NATO for supporting this workshop via a grant to the co-directors. The objective of ARW was to explore the various facets of regenerative me- cine and to highlight role of the “the nano-length scale” and “nano-scale systems” in defining and controlling cell and tissue environments. The development of novel tissue regenerative strategies require the integration of new insights emerging from studies of cell-matrix interactions, cellular signalling processes, developmental and systems biology, into biomaterials design, via a systems approach. The chapters in the book, written by the leading experts in their respective disciplines, cover a wide spectrum of topics ranging from stem cell biology, developmental biology, ce- matrix interactions, and matrix biology to surface science, materials processing and drug delivery. We hope the contents of the book will provoke the readership into developing regenerative medicine paradigms that combine these facets into cli- cally translatable solutions. This NATO meeting would not have been successful without the timely help of Dr. Ulrike Shastri, Sanjeet Rangarajan and Ms. Sabine Benner, who assisted in the organization and implementation of various elements of this meeting. Thanks are also due Dr. Fausto Pedrazzini and Ms. Alison Trapp at NATO HQ (Brussels, Belgium). The commitment and persistence of Ms.

Principles of Regenerative Biology

Bruce M. Carlson
Principles of Regenerative Biology Book PDF

Author : Bruce M. Carlson
Publisher : Elsevier
Page : 400 pages
File Size : 44,8 Mb
Release : 2011-10-10
Category : Science
ISBN : 0080477968

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Principles of Regenerative Biology by Bruce M. Carlson Pdf

With the explosion of knowledge from molecular biology and the burgeoning interest in generating or regenerating tissues or organs through various bioengineering or stem cell approaches, many scientists and students have shown a renewed interest in the phenomenon of regeneration. Because relatively few have had the luxury of being able to approach the phenomenon of regeneration from a broad biological perspective, Dr. Carlson has produced a book that outlines the fundamental principles of regeneration biology. Subject matters focus principally on regeneration in vertebrate systems, but also invertebrate regeneration. In order to manipulate regenerative processes, it is important to understand the underlying principles of regeneration. Principles of Regnerative Biology is the key introductory reference for all developmental biologists, geneticists, and tissue and stem cell researchers. Creates a general understanding of one of the most fascinating and complex phenomena in biology Discusses the ability and diversity of regeneration in various organisms Explains the history and origins of cells in regenerating systems Includes information on stem cells and its important role in regeneration

Regenerative Engineering

Yusuf Khan,Cato T. Laurencin
Regenerative Engineering Book PDF

Author : Yusuf Khan,Cato T. Laurencin
Publisher : CRC Press
Page : 322 pages
File Size : 51,7 Mb
Release : 2018-04-19
Category : Medical
ISBN : 9781351647397

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Regenerative Engineering by Yusuf Khan,Cato T. Laurencin Pdf

This book focuses on advances made in both materials science and scaffold development techniques, paying close attention to the latest and state-of-the-art research. Chapters delve into a sweeping variety of specific materials categories, from composite materials to bioactive ceramics, exploring how these materials are specifically designed for regenerative engineering applications. Also included are unique chapters on biologically-derived scaffolding, along with 3D printing technology for regenerative engineering. Features: Covers the latest developments in advanced materials for regenerative engineering and medicine. Each chapter is written by world class researchers in various aspects of this medical technology. Provides unique coverage of biologically derived scaffolding. Includes separate chapter on how 3D printing technology is related to regenerative engineering. Includes extensive references at the end of each chapter to enhance further study.