Regulation Of Soluble Immune Mediators By Non Coding Rnas

Author : Flavia Bazzoni,Daniela Bosisio
Publisher : Frontiers Media SA
Page : 138 pages
File Size : 43,5 Mb
Release : 2020-12-11
Category : Medical
ISBN : 9782889662104

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Regulation of Soluble Immune Mediators by Non-Coding RNAs by Flavia Bazzoni,Daniela Bosisio Pdf

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Author : Diana Boraschi,Giselle Penton-Rol,Marita Troye Blomberg,Olukemi Amodu
Publisher : Frontiers Media SA
Page : 848 pages
File Size : 53,6 Mb
Release : 2024-02-13
Category : Medical
ISBN : 9782832544341

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Women in Cytokines and Soluble Mediators in Immunity by Diana Boraschi,Giselle Penton-Rol,Marita Troye Blomberg,Olukemi Amodu Pdf

We are delighted to present the inaugural Frontiers in Immunology “Women in Cytokines and Soluble Mediators in Immunity” series of article collections. At present, less than 30% of researchers worldwide are women. Long-standing biases and gender stereotypes are discouraging girls and women away from science-related fields, and Science, Technology, Engineering and Mathematics (STEM) research in particular. Science and gender equality are, however, essential to ensure sustainable development as highlighted by UNESCO. In order to change traditional mindsets, gender equality must be promoted, stereotypes defeated, and girls and women should be encouraged to pursue STEM careers.

Author : Bertrand Kaeffer,Antoine Louveau,Chen Chen
Publisher : Frontiers Media SA
Page : 203 pages
File Size : 47,7 Mb
Release : 2023-01-02
Category : Medical
ISBN : 9782832510360

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Non-coding RNA in immunotherapies and immune regulation by Bertrand Kaeffer,Antoine Louveau,Chen Chen Pdf

Author : Giovanni Blandino,Hernandes F. Carvalho,Jawed A. Siddiqui,Valeria Poli
Publisher : Frontiers Media SA
Page : 256 pages
File Size : 50,6 Mb
Release : 2023-01-05
Category : Medical
ISBN : 9782832510667

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Roles Of Non-coding RNAs In Tumor Growth And Development by Giovanni Blandino,Hernandes F. Carvalho,Jawed A. Siddiqui,Valeria Poli Pdf

Author : Junjie Xiao
Publisher : Springer
Page : 426 pages
File Size : 43,5 Mb
Release : 2021-04-28
Category : Science
ISBN : 9811516731

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Non-coding RNAs in Cardiovascular Diseases by Junjie Xiao Pdf

This book presents the latest research on non-coding RNAs in cardiovascular disease, a major cause of death worldwide. Non-coding RNAs play a significant role in development, proliferation, differentiation and apoptosis. Since altered non-coding RNA expression is often associated with various diseases, their potential use in diagnostics, prognostics and therapeutics is an important current area of study. The book consists of six parts: 1) An overview of non-coding RNAs and cardiovascular system, 2) Bioinformatics and interactions, 3) Non-coding RNA regulation in cardiovascular system, 4) Non-coding RNAs and cardiovascular diseases, 5) Potential biomarkers and therapeutic implications, 6) Future prospects. It is particularly useful for researchers and students in the field of non-coding RNA and cardiovascular biology, as well as for cardiologists, pharmacologists and physiologists.

Author : Aamir Ahmad,Palmiro Poltronieri,Shahab Uddin
Publisher : Frontiers Media SA
Page : 445 pages
File Size : 41,7 Mb
Release : 2023-10-30
Category : Medical
ISBN : 9782832526125

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lncRNAs in Cancer Metastasis and Therapy Resistance by Aamir Ahmad,Palmiro Poltronieri,Shahab Uddin Pdf

lncRNAs (long non-coding RNAs) are the relatively longer (more than 200 nucleotides long) subtypes of ncRNAs (non-coding RNAs) i.e the RNAs that do not code for any proteins. However, even without themselves being translated, lncRNAs impact the cellular gene expressions and functions in ways that are just beginning to be explored. The metastasis of human cancers as well as acquired resistance against the administered therapeutics are two major factors responsible for the cancer-associated mortality.

Author : Maria Teresa Cencioni,Roberta Magliozzi,Luisa María Villar
Publisher : Frontiers Media SA
Page : 220 pages
File Size : 55,9 Mb
Release : 2023-04-10
Category : Medical
ISBN : 9782832520147

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Reassessing the immune system contribution in multiple sclerosis: Therapeutic target, biomarkers of disease and immune pathogenesis by Maria Teresa Cencioni,Roberta Magliozzi,Luisa María Villar Pdf

Author : Martial Ruat
Publisher : Springer
Page : 210 pages
File Size : 41,7 Mb
Release : 2015-06-23
Category : Science
ISBN : 9783319197555

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The Smoothened Receptor in Cancer and Regenerative Medicine by Martial Ruat Pdf

Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.

Author : Pedro Baptista
Publisher : BoD – Books on Demand
Page : 266 pages
File Size : 55,9 Mb
Release : 2012-05-16
Category : Technology & Engineering
ISBN : 9789535106227

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Liver Regeneration by Pedro Baptista Pdf

Doctors and scientists have been aware of the "phenomenom" of liver regeneration since the time of the ancient Greeks, illustrated by the mythic tale of Prometheus' punishment. Nevertheless, true insight into its intricate mechanisms have only become available in the 20th century. Since then, the pathways and mechanisms involved in restoring the liver to its normal function after injury have been resolutely described and characterized, from the hepatic stem/progenitor cell activation and expansion to the more systemic mechanisms involving other tissues and organs like bone-marrow progenitor cell mobilization. This book describes some of the complex mechanisms involved in liver regeneration and provides examples of the most up-to-date strategies used to induce liver regeneration, both in the clinic and in the laboratory. The information presented will hopefully benefit not only professionals in the liver field, but also people in other areas of science (pharmacology, toxicology, etc) that wish to expand their knowledge of the fundamental biology that orchestrates liver injury and regeneration.

Author : Michel Félétou
Publisher : Morgan & Claypool Publishers
Page : 309 pages
File Size : 50,5 Mb
Release : 2011
Category : Science
ISBN : 9781615041237

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The Endothelium by Michel Félétou Pdf

The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells. The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen species and so on. Additionally, endothelial ectoenzymes are required steps in the generation of vasoactive hormones such as angiotensin II. An endothelial dysfunction linked to an imbalance in the synthesis and/or the release of these various endothelial factors may explain the initiation of cardiovascular pathologies (from hypertension to atherosclerosis) or their development and perpetuation. Table of Contents: Introduction / Multiple Functions of the Endothelial Cells / Calcium Signaling in Vascular Cells and Cell-to-Cell Communications / Endothelium-Dependent Regulation of Vascular Tone / Conclusion / References

Author : Catherine M. Greene
Publisher : Springer
Page : 237 pages
File Size : 51,9 Mb
Release : 2015-02-06
Category : Medical
ISBN : 9783319136899

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MicroRNAs and Other Non-Coding RNAs in Inflammation by Catherine M. Greene Pdf

The book serves as a comprehensive resource for scientists and clinicians studying the role of non-coding RNAs in inflammation (viral infections, wound inflammation), human inflammatory diseases (i.e. rheumatoid arthritis, Crohn’s disease, diabetes) and innate immunity. It provides a universal reference work comprising both basic and specialized information. Given that ncRNAs represent new therapeutic targets, this volume will also be of interest to industrial biomedical researchers and those involved in drug development.

Author : Jian-Guo Zhou,Zhaohui Huang,Ondrej Slaby,Alfons Navarro
Publisher : Frontiers Media SA
Page : 599 pages
File Size : 47,5 Mb
Release : 2021-03-23
Category : Medical
ISBN : 9782889666096

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The Role of ncRNAs in Solid Tumors Prognosis: From Laboratory To Clinical Utility by Jian-Guo Zhou,Zhaohui Huang,Ondrej Slaby,Alfons Navarro Pdf

Author : Karl L. Mettinger,Pranela Rameshwar,Vinod Kumar
Publisher : Springer
Page : 154 pages
File Size : 51,7 Mb
Release : 2018-05-12
Category : Science
ISBN : 9783319744704

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Exosomes, Stem Cells and MicroRNA by Karl L. Mettinger,Pranela Rameshwar,Vinod Kumar Pdf

This volume provides insight into the pivotal roles of stem cells, exosomes and other microvesicles in biofunction and molecular mechanisms and their therapeutic potential in translational nanomedicine. It further highlights evidence from recent studies as to how stem cell derived exosomes and microRNAs may restore and maintain tissue homeostasis, enable cells to recover critical cellular functions and begin repair regeneration. These early studies in animal models of aging also show evidence of improved immune, cardiovascular and cognitive functions as well as improved health span and life span. The use of exosomes from body fluids to define specific biomarkers for various tumors may also clear the path to patient-targeted treatments by developing exosome-derived microRNA based cancer therapeutics. It is essential reading for graduate students, research fellow and biomedical researchers in academia or the pharmaceutical or biotech industries.

Author : Amanda Salviano-Silva,Ticiana D. J. Farias,Angelica Beate Winter Boldt,Gabriel Adelman Cipolla
Publisher : Frontiers Media SA
Page : 141 pages
File Size : 42,8 Mb
Release : 2023-01-11
Category : Science
ISBN : 9782832511305

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Genetic and epigenetic aspects of non-coding RNAs in physiology and disease by Amanda Salviano-Silva,Ticiana D. J. Farias,Angelica Beate Winter Boldt,Gabriel Adelman Cipolla Pdf

Author : Syamal Kumar Datta,Antonio La Cava,David A. Horwitz,Ciriaco A. Piccirillo
Publisher : Frontiers Media SA
Page : 133 pages
File Size : 46,5 Mb
Release : 2022-08-19
Category : Medical
ISBN : 9782889747887

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Generating and Sustaining Stable Autoantigen-specific CD4 and CD8 Regulatory T Cells in Lupus by Syamal Kumar Datta,Antonio La Cava,David A. Horwitz,Ciriaco A. Piccirillo Pdf