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Author : Alma D. Campos-Parra,Carlos Pérez-Plasencia,Teresita Padilla-Benavides,Eduardo López-Urrutia
Publisher : Frontiers Media SA
Page : 158 pages
File Size : 53,7 Mb
Release : 2021-08-26
Category : Medical
ISBN : 9782889712397
Author : Suraj P. Parihar,Shashank Gupta,Makram Essafi,Bibhuti Mishra,Ramandeep Singh
Publisher : Frontiers Media SA
Page : 144 pages
File Size : 54,8 Mb
Release : 2022-03-04
Category : Medical
ISBN : 9782889743704
Author : Jeannine Stein
Publisher : Quarto Publishing Group USA
Page : 145 pages
File Size : 48,8 Mb
Release : 2009-07-01
Category : Crafts & Hobbies
ISBN : 9781616735517
A DIY book making guide that repurposes easily-found items into handcrafted books, perfect for gift giving. Re-Bound is a beautiful book on bookbinding with a fun green twist—all the projects use recycled and upcycled materials. This book shows you how to take everyday materials from around the house, flea markets, thrift stores, and hardware stores and turn them into clever and eye-catching hand-made books.
Author : Ranbir Chander Sobti,Sunil K. Lal,Ramesh K. Goyal
Publisher : Springer Nature
Page : 664 pages
File Size : 44,8 Mb
Release : 2023-02-07
Category : Medical
ISBN : 9789811953996
This book presents drug repurposing strategies to combat infectious diseases and cancer. It discusses key experimental and in silico approaches for modern drug repositioning, including signature matching, molecular docking, genome-wide associated studies, and network-based approaches aided by artificial intelligence. Further, the book presents various computational and experimental strategies for better understanding disease mechanisms and identify repurposed drug candidates for personalized pharmacotherapy. It also explores the databases for drug repositioning, summarizes the approaches taken for drug repositioning, and highlights and compares their characteristics and challenges. Towards the end, the book discusses challenges and limitations encountered in computational drug repositioning.
Author : Noe Garcia
Publisher : B&H Publishing Group
Page : 137 pages
File Size : 55,7 Mb
Release : 2021-10-19
Category : Religion
ISBN : 9781087740508
Have you ever thought your life is beyond repair? Perhaps you asked, “How could God possibly use my brokenness for good?” We all tend to look for purpose in our pain. We are broken people living in a broken world. Depression, anxiety, hurting relationships, unmet expectations, and just that constant feeling of unease and discouragement make us question God, wondering if there is even a purpose to be found. In Repurposed, Noe Garcia takes readers on a journey through Romans 8, which many have called “The Greatest Chapter in the Bible.” Noe shares his life story, including abuse, depression, and overwhelming hopelessness. He reveals how God has redeemed him, repaired his brokenness, and restored him to new life. Whether your life is like Noe's was, or your brokenness looks different, this book will meet you where you are, and: Provide hope for your future. Remind you of the promise that God is for you. Lead you to surrender your brokenness to God. Help you see how God is using all things together for your good.
Author : David Cavalla
Publisher : Royal Society of Chemistry
Page : 351 pages
File Size : 49,6 Mb
Release : 2022-02-09
Category : Business & Economics
ISBN : 9781788019033
Drug repurposing, or repositioning, is the development of existing drugs for new uses: given that 9 in 10 drugs that enter drug development are never marketed and therefore represent wasted effort, it is an attractive as well as inherently more efficient process. Three repurposed drugs can be brought to market for the same cost as one new chemical entity; and they can also be identified more quickly, an important benefit for patients whose diseases are progressing faster than therapeutic innovation. But repurposing also requires a fresh look at configuring pharmaceutical R&D, considering clinical, regulatory and patent issues much earlier than would otherwise be the case. In addition to new ways of thinking, the discovery of repurposing opportunities can take advantage of artificial intelligence techniques to match the perfect new use for an existing drug. This book provides an ideal introduction to the field of drug repurposing with contributions from world-renowned experts culminating in an excellent resource for any drug discovery or medicinal chemist.
Author : Shailendra K. Saxena
Publisher : BoD – Books on Demand
Page : 385 pages
File Size : 48,7 Mb
Release : 2022-06-01
Category : Medical
ISBN : 9781839699573
This book focuses on various aspects and applications of drug repurposing, the understanding of which is important for treating diseases. Due to the high costs and time associated with the new drug discovery process, the inclination toward drug repurposing is increasing for common as well as rare diseases. A major focus of this book is understanding the role of drug repurposing to develop drugs for infectious diseases, including antivirals, antibacterial and anticancer drugs, as well as immunotherapeutics.
Author : Ramarao Poduri,Gaurav Joshi,Mayank Sharma,Asim Kumar
Publisher : Walter de Gruyter GmbH & Co KG
Page : 352 pages
File Size : 49,6 Mb
Release : 2023-10-02
Category : Science
ISBN : 9783110791525
Drug repurposing, or drug repositioning, or reprofiling, has emerged as a valid approach in modern drug discovery. The book describes tools and techniques for identifying new therapeutic potentials for existing drugs and covers the repurposing of drugs from synthetic and natural origin. It compares the costs of drug repurposing with traditional drug discovery and discusses challenges and future perspectives of drug repurposing.
Author : Tabish Qidwai
Publisher : Bentham Science Publishers
Page : 206 pages
File Size : 42,8 Mb
Release : 2023-04-14
Category : Medical
ISBN : 9789815123197
Drug repurposing is a cost-effective method of discovering new treatments for diseases than traditional drug development methods. It involves virtual screening of chemical candidates with the aid of computational methods like molecular docking. Drug Repurposing against SARS-CoV2 focuses on current trends in drug repurposing against the novel coronavirus strains. The book aims to give readers an overview of drug repurposing against COVID-19 and various techniques involved in the process. The book consolidates available information on the pathophysiology, drug targets, and drug repurposing against COVID-19 into a single, convenient resource. Key features • An up-to-date compilation of the evidence that supports the drug repurposing for COVID-19. • How to use repurposing of available drugs for disease therapy. • Provides an improved understanding of pathophysiology and SARS-CoV2 viral entry pathways. • Provides references for further reading
Author : Mithun Rudrapal,Rudra Pangeni,Keshav Raj Paudel
Publisher : Frontiers Media SA
Page : 170 pages
File Size : 49,5 Mb
Release : 2023-01-30
Category : Science
ISBN : 9782832512623
Author : Ronni Kahn,Jessica Chapnik Kahn
Publisher : Allen & Unwin
Page : 320 pages
File Size : 51,6 Mb
Release : 2020-09-29
Category : Biography & Autobiography
ISBN : 9781761060243
'From the founder of OzHarvest, an ebullient, generous memoir with an exhilarating message.' ANNABEL CRABB 'Brimming with energy, altruism and refreshing candour' QUENTIN BRYCE 'The inspiring story of a woman with a big heart who dared to make a difference. This is a must-read book. I couldn't put it down.' ITA BUTTROSE 'Ronni Kahn is a force of nature. She has taught so many of us about the importance of embracing community and compassion through offering and sharing our food to those most vulnerable in our society.' KYLIE KWONG 'You don't get used to living permanently behind the eight ball - no matter how long you've done it, it doesn't get easier. There's a constant sense of shame that eats away at you, making you feel that you're just not good enough. Some people are so poor that they can't even afford to feel shame. Ronni Kahn, through her work with OzHarvest, does the very thing that offers hope to those in the poverty trap: restore dignity and remove shame. This is her story.' JIMMY BARNES 'Ronni Kahn is a one-woman freight train for the force of good. She is living testament to the awesome power of living in a way that is real and wholehearted, and whether people know it or not, that is why they are drawn to her. This book is not only a beautifully conveyed account of Ronni's story, but it also serves as inspiration for anyone who chooses to see life's challenges as opportunities to grow. Through serving others, there is the very real possibility we may find a sense of purpose, connectedness and joy.' MELISSA LEONG 'Inspiring, wonderfully honest and very much needed.' TIM FLANNERY Life throws us mysterious ingredients. If we are brave enough to put the recipe aside and experiment, it's right there that things get interesting. As the owner of a successful events company, throwing away huge volumes of leftover food at the end of the day came with the territory. But when Ronni Kahn hit midlife, she found herself no longer able to turn a blind eye to her food waste problem. Hand delivering the untouched food to homeless shelters around Sydney became her renegade solution. Little did she know that fixing her small problem at work would lead her to unlock a hidden purpose at the very core of her inner life. Now founder and CEO of the food rescue organisation OzHarvest, Ronni leads hundreds of staff and thousands of volunteers with the goal to nourish Australia. She serves in an advisory capacity to government and is an instrumental leader in changing federal laws to improve social justice and environmental policies. A Repurposed Life is the story of how Ronni found her voice, her heart and her deepest calling. From her early years growing up under the brutal system of apartheid South Africa, to a socialist commune in Israel, Ronni finally settled in Australia to discover a profound new way of living. Shared with the humour, warmth and energy that have made her an internationally renowned keynote speaker, this heartfelt exploration of the choices that define us will speak to anyone seeking a more passionate expression of being alive.
Author : Farid A. Badria
Publisher : BoD – Books on Demand
Page : 236 pages
File Size : 54,6 Mb
Release : 2020-12-02
Category : Medical
ISBN : 9781839685200
Drug repurposing or drug repositioning is a new approach to presenting new indications for common commercial and clinically approved existing drugs. For example, chloroquine, an old antimalarial drug, showed promising results for treating COVID-19, interfering with MDR in several types of cancer, and chemosensitizing human leukemic cells.This book focuses on the hypothesis, risk/benefits, and economic impacts of drug repurposing on drug discovery in dermatology, infectious diseases, neurological disorders, cancer, and orphan diseases. It brings together up-to-date research to provide readers with an informative, illustrative, and easy-to-read book useful for students, clinicians, and the pharmaceutical industry.
Author : Lily Fulop
Publisher : The Countryman Press
Page : 211 pages
File Size : 50,6 Mb
Release : 2020-03-31
Category : Crafts & Hobbies
ISBN : 9781682684351
In with the old, out with the new—reclaiming your closet and reducing fashion waste starts here. Repair your favorite socks with style, add flair with personalized patches, and turn ripped jeans into an embroidered masterpiece. For beginner and experienced makers, Lily Fulop's guide to mending and upcycling is your colorful companion to ditching fast fashion and extending the lifecycle of all your favorite clothes. Fulop's vibrant step-by-step illustrations make mending easier than every, demystifying techniques and displaying unique ways to show off your personality. And when your mending possibilities run out, she has simple yet striking solutions to repurpose fabric, including braided rugs, crocheted pillows, and more. Say hello to sustainable inspiration.
Author : Mithun Rudrapal
Publisher : BoD – Books on Demand
Page : 225 pages
File Size : 46,5 Mb
Release : 2023-06-07
Category : Medical
ISBN : 9781837687763
Drug repurposing (or drug repositioning) is defined as the process of identifying new pharmacological indications of old, existing, investigational, or FDA-approved drugs for use in the treatment of diseases other than the drugs’ original intended therapeutic use. Drug Repurposing - Advances, Scopes and Opportunities in Drug Discovery delivers up-to-date information on the identification of newer uses, molecular mechanisms, and novel targets of existing drug candidates through the application of various experimental, biophysical, and computational approaches and techniques. Chapters discuss recent advances in drug repurposing strategies that are currently being used in the discovery and development of drugs against difficult-to-treat, rare, and life-threatening diseases, including microbial infections, COVID-19, parasitic diseases, cardiovascular diseases, neurological disorders, and cancer. The book also discusses the modern experimental assays (HTS) and computational techniques including informatics and databases, molecular docking and dynamics, artificial intelligence and machine learning, virtual screening and pharmacophore modeling, proteomics and metabolomics, and network pharmacology and systems biology approaches. Some of the key features of the book are: • Presents the strategies available for the development of drugs by drug repurposing approaches through various experimental and computational techniques for the treatment of difficult-to-treat, rare, and deadly diseases • Summarizes the latest advances in the application of drug repurposing strategies, techniques, and approaches in the discovery and development of drugs • Depicts drug development approaches from existing drug candidates and/or lead molecules through modern experimental assays, biophysical tools, and computational techniques Written by a global team of experts, this book is useful for drug discovery scientists, drug developers, medicinal chemists, phytochemists, pharmacologists, clinicians, biochemists, biomedical scientists, healthcare professionals, researchers, teaching faculty, and students.
Author : Ganji Purnachandra Nagaraju,Venkatesan Amouda,Ampasala Dinakara Rao
Publisher : Elsevier
Page : 460 pages
File Size : 42,9 Mb
Release : 2023-03-22
Category : Computers
ISBN : 9780443152818
Computational Methods in Drug Discovery and Repurposing for Cancer Therapy provides knowledge about ongoing research as well as computational approaches for drug discovery and repurposing for cancer therapy. The book also provides detailed descriptions about target molecules, pathways, and their inhibitors for easy understanding and applicability. The book discusses tools and techniques such as integrated bioinformatics approaches, systems biology tools, molecular docking, computational chemistry, artificial intelligence, machine learning, structure-based virtual screening, biomarkers, and transcriptome; those are discussed in the context of different cancer types, such as colon, pancreatic, glioblastoma, endometrial, and retinoblastoma, among others. This book is a valuable resource for researchers, students, and members of the biomedical and medical fields who want to learn more about the use of computational modeling to better tailor the treatment for cancer patients. Discusses in silico remodeling of effective phytochemical compounds for discovering improved anticancer agents for substantial/significant cancer therapy Covers potential tools of bioinformatics that are applied toward discovering new targets by drug repurposing and strategies to cure different types of cancers Demonstrates the significance of computational and artificial intelligence approaches in anticancer drug discovery Explores how these various advances can be integrated into a precision and personalized medicine approach that can eventually enhance patient care