Respiratory Physiology Of Newborn Mammals

Author : Jacopo P. Mortola
Publisher : JHU Press
Page : 363 pages
File Size : 48,6 Mb
Release : 2003-04-30
Category : Science
ISBN : 9780801873669

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Respiratory Physiology of Newborn Mammals by Jacopo P. Mortola Pdf

Respiratory Physiology of Newborn Mammals: A Comparative Perspective emphasizes common trends among mammalian species in an effort to extract general rules about both the structure and the mechanisms of neonatal respiration. Jacopo P. Mortola outlines the key aspects of developmental respiratory physiology in the perinatal period. Based on what is learned from interspecies comparisons, Mortola addresses the question of how pulmonary ventilation fulfills the metabolic requirements of the newborn infant. Exceptions to the rules illuminate adaptations to particular tasks or conditions. Each chapter concludes with interspecies comparisons and clinical implications for the medically or zoologically oriented reader. The combination of developmental and comparative perspectives offers an original contribution to the field of developmental physiology. The book is divided into five chapters: "Gestation and Birth," Metabolic and Ventilatory Requirements," "Mechanical Behavior of the Respiratory Pump," "Reflex Control of the Breathing Pattern," and "Changes in Temperature and Respiratory Gases." It will be of value to researchers, clinicians, and students interested in developmental physiology, comparative biology, and zoology, as well as neonatalogists and pediatric pulmonologists who are interested in alternative perspectives on current clinical practice.

Author : Gabriel G. Haddad,Steven H. Abman,Victor Chernick
Publisher : PMPH-USA
Page : 568 pages
File Size : 45,9 Mb
Release : 2002
Category : Children
ISBN : 155009159X

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Chernick-Mellins Basic Mechanisms of Pediatric Respiratory Disease by Gabriel G. Haddad,Steven H. Abman,Victor Chernick Pdf

This second edition of the landmark 1991 text, Basic Mechanisms of Pediatric Respiratory Disease reviews the importance of the integrations of molecular, cellular and physiologic strategies in the development of a new understanding of pediatric respiratory disorders. It provides state-of-the-art information about fundamental mechanisms underlying ......

Author : Alan H. Jobe,Jeffrey A. Whitsett,Steven H. Abman
Publisher : Cambridge University Press
Page : 128 pages
File Size : 45,8 Mb
Release : 2016-04-18
Category : Medical
ISBN : 9781316665176

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Fetal and Neonatal Lung Development by Alan H. Jobe,Jeffrey A. Whitsett,Steven H. Abman Pdf

Lung disease affects more than 600 million people worldwide. While some of these lung diseases have an obvious developmental component, there is growing appreciation that processes and pathways critical for normal lung development are also important for postnatal tissue homeostasis and are dysregulated in lung disease. This book provides an authoritative review of fetal and neonatal lung development and is designed to provide a diverse group of scientists, spanning the basic to clinical research spectrum, with the latest developments on the cellular and molecular mechanisms of normal lung development and injury-repair processes, and how they are dysregulated in disease. The book covers genetics, omics, and systems biology as well as new imaging techniques that are transforming studies of lung development. The reader will learn where the field of lung development has been, where it is presently, and where it is going in order to improve outcomes for patients with common and rare lung diseases.

Author : National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Committee on Guidelines for the Use of Animals in Neuroscience and Behavioral Research
Publisher : National Academies Press
Page : 223 pages
File Size : 52,9 Mb
Release : 2003-08-22
Category : Science
ISBN : 9780309167857

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Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research by National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Committee on Guidelines for the Use of Animals in Neuroscience and Behavioral Research Pdf

Expanding on the National Research Council's Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animal's well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.

Author : Roger S. Seymour
Publisher : Springer Science & Business Media
Page : 439 pages
File Size : 44,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789400965362

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Respiration and metabolism of embryonic vertebrates by Roger S. Seymour Pdf

The papers in this volume were presented at an international symposium, held in South Australia on September 8-10, 1983. The purpose of the meeting was to present the comparative physiology of gas exchange, water balance and energet ics of developing vertebrate embryos. contributions were invited from leading research workers in an attempt to represent the forefront of investigation of all vertebrate classes and to promote a broadly comparative approach to the study of embryonic physiology. These proceedings therefore reflect the current level of research activity focus ing on each group of vertebrates. While considerable expansion and specializa tion has occurred in the area of avian embryos over the last decade, work on reptilian embryos is less developed and that on fish and amphibians is still in its infancy. Although a great deal is known about respiration and metabolism in embryos of placental mammals, the physiology associated with the curious mode of development of monotreme and marsupial embryos has not been examined until recently. In this symposium. the well-studied vertebrate classes are repre sented primarily by specific research papers that document original work. These are balanced by more extensive reviews of the lesser known classes.

Author : Shyamala Dakshinamurti
Publisher : CRC Press
Page : 268 pages
File Size : 52,9 Mb
Release : 2021-10-29
Category : Medical
ISBN : 9781000442328

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Hypoxic Respiratory Failure in the Newborn by Shyamala Dakshinamurti Pdf

We have all been hypoxic. Fetal tolerance for intrauterine hypoxia arises from evolutionarily conserved physiological mechanisms, the antecedents of which can be learned from diving mammals or species at high altitudes. Understanding fetal hypoxia leads to understanding the huge physiological shifts of neonatal transition and the dangers of perinatal hypoxia. This comprehensive volume of topical review articles by expert authors addresses the origins of hypoxia tolerance, the impact of oxygen on circulatory transition at birth, and the biochemistry of hypoxia in the pulmonary circuit, as well as the classification, diagnosis, and clinical management of hypoxic respiratory failure and persistent pulmonary hypertension in the term neonate. The goal of Hypoxic Respiratory Failure in the Newborn is to connect our understanding of hypoxia from animals in extreme environments, with how the human fetus handles its hypoxic environment; and why the human newborn suddenly cannot. The book will educate health care professionals on how to care for newborns with hypoxic respiratory failure, including the use of up-to-date diagnostic tools and therapies. It also highlights areas of controversy and ongoing research in hypoxic respiratory failure and pulmonary hypertension of the newborn, including challenging case studies. Key Features Explores evolutionary context and comparative physiology of hypoxia tolerance in the fetus and neonate, from basic research to clinical scenarios Provides guidance to trainees, physicians, and allied health professionals engaged in NICU care; pediatricians, cardiologists, pulmonologists, anesthesiologists, neonatologists, and physiologists to effectively manage infants in hypoxic respiratory failure Includes case scenarios emphasizing current diagnostic and therapeutic controversies and algorithmic approaches to decipher difficult clinical cases

Author : G. Benchetrit,P. Baconnier,Jacques Demongeot
Publisher : Manchester University Press
Page : 424 pages
File Size : 42,6 Mb
Release : 1987
Category : Biological models
ISBN : 071902322X

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Concepts and Formalizations in the Control of Breathing by G. Benchetrit,P. Baconnier,Jacques Demongeot Pdf

Author : Richard A. Polin,Steven H. Abman
Publisher : Elsevier Health Sciences
Page : 2202 pages
File Size : 55,8 Mb
Release : 2011-08-13
Category : Medical
ISBN : 9781437736366

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Fetal and Neonatal Physiology E-Book by Richard A. Polin,Steven H. Abman Pdf

Fetal and Neonatal Physiology, edited by Drs. Polin, Fox, and Abman, focuses on physiologic developments of the fetus and newborn and their impact on the clinical practice of neonatology. A must for practice, this 4th edition brings you the latest information on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. Gain a comprehensive, state-of-the-art understanding of normal and abnormal physiology, and its relationship to disease in the fetus and newborn premature infant, from Dr. Richard Polin and other acknowledged worldwide leaders in the field. Understand the implications of fetal and neonatal physiology through chapters devoted to clinical correlation. Apply the latest insights on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. Effectively manage the consequences of intrauterine infections with three new chapters covering intrauterine infection and preterm birth, intrauterine infection and brain injury, and intrauterine infection and chronic lung disease.

Author : Richard A. Polin,William W. Fox,Steven H. Abman
Publisher : Elsevier Health Sciences
Page : 2213 pages
File Size : 41,9 Mb
Release : 2011-01-01
Category : Medical
ISBN : 9781416034797

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Fetal and Neonatal Physiology by Richard A. Polin,William W. Fox,Steven H. Abman Pdf

Fetal and Neonatal Physiology, edited by Drs. Polin, Fox, and Abman, focuses on physiologic developments of the fetus and newborn and their impact on the clinical practice of neonatology. A must for practice, this 4th edition brings you the latest information on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. You'll also have easy access to the complete contents and illustrations online at expertconsult.com. Gain a comprehensive, state-of-the-art understanding of normal and abnormal physiology, and its relationship to disease in the fetus and newborn premature infant, from Dr. Richard Polin and other acknowledged worldwide leaders in the field. Understand the implications of fetal and neonatal physiology through chapters devoted to clinical correlation. Apply the latest insights on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. Effectively manage the consequences of intrauterine infections with three new chapters covering intrauterine infection and preterm birth, intrauterine infection and brain injury, and intrauterine infection and chronic lung disease. Access the complete contents and illustrations online at expertconsult.com - fully searchable! Get the latest developments and a full understanding of the distinct physiology of the fetus and newborn so you can treat and manage sick newborns and preemies.

Author : Peter C. Rimensberger
Publisher : Springer
Page : 1584 pages
File Size : 51,7 Mb
Release : 2014-11-12
Category : Medical
ISBN : 9783642012198

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Pediatric and Neonatal Mechanical Ventilation by Peter C. Rimensberger Pdf

Written by outstanding authorities from all over the world, this comprehensive new textbook on pediatric and neonatal ventilation puts the focus on the effective delivery of respiratory support to children, infants and newborns. In the early chapters, developmental issues concerning the respiratory system are considered, physiological and mechanical principles are introduced and airway management and conventional and alternative ventilation techniques are discussed. Thereafter, the rational use of mechanical ventilation in various pediatric and neonatal pathologies is explained, with the emphasis on a practical step-by-step approach. Respiratory monitoring and safety issues in ventilated patients are considered in detail, and many other topics of interest to the bedside clinician are covered, including the ethics of withdrawal of respiratory support and educational issues. Throughout, the text is complemented by numerous illustrations and key information is clearly summarized in tables and lists.

Author : Kenneth P. Dial,Neil Shubin,Elizabeth L. Brainerd
Publisher : University of Chicago Press
Page : 435 pages
File Size : 51,8 Mb
Release : 2015-07-20
Category : Science
ISBN : 9780226268392

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Great Transformations in Vertebrate Evolution by Kenneth P. Dial,Neil Shubin,Elizabeth L. Brainerd Pdf

How did flying birds evolve from running dinosaurs, terrestrial trotting tetrapods evolve from swimming fish, and whales return to swim in the sea? These are some of the great transformations in the 500-million-year history of vertebrate life. And with the aid of new techniques and approaches across a range of fields—work spanning multiple levels of biological organization from DNA sequences to organs and the physiology and ecology of whole organisms—we are now beginning to unravel the confounding evolutionary mysteries contained in the structure, genes, and fossil record of every living species. This book gathers a diverse team of renowned scientists to capture the excitement of these new discoveries in a collection that is both accessible to students and an important contribution to the future of its field. Marshaling a range of disciplines—from paleobiology to phylogenetics, developmental biology, ecology, and evolutionary biology—the contributors attack particular transformations in the head and neck, trunk, appendages such as fins and limbs, and the whole body, as well as offer synthetic perspectives. Illustrated throughout, Great Transformations in Vertebrate Evolution not only reveals the true origins of whales with legs, fish with elbows, wrists, and necks, and feathered dinosaurs, but also the relevance to our lives today of these extraordinary narratives of change.

Author : Roger W. Byard,Jhodie R Duncan
Publisher : Unknown
Page : 844 pages
File Size : 44,9 Mb
Release : 2018-04
Category : Medical
ISBN : 1925261670

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SIDS Sudden Infant and Early Childhood Death by Roger W. Byard,Jhodie R Duncan Pdf

This volume covers aspects of sudden infant and early childhood death, ranging from issues with parental grief, to the most recent theories of brainstem neurotransmitters. It also deals with the changes that have occurred over time with the definitions of SIDS (sudden infant death syndrome), SUDI (sudden unexpected death in infancy) and SUDIC (sudden unexpected death in childhood). The text will be indispensable for SIDS researchers, SIDS organisations, paediatric pathologists, forensic pathologists, paediatricians and families, in addition to residents in training programs that involve paediatrics. It will also be of use to other physicians, lawyers and law enforcement officials who deal with these cases, and should be a useful addition to all medical examiner/forensic, paediatric and pathology departments, hospital and university libraries on a global scale. Given the marked changes that have occurred in the epidemiology and understanding of SIDS and sudden death in the very young over the past decade, a text such as this is very timely and is also urgently needed.

Author : Rajiv PK,Satyan Lakshminrusimha,Dharmapuri Vidyasagar
Publisher : Elsevier Health Sciences
Page : 128 pages
File Size : 47,6 Mb
Release : 2018-12-05
Category : Medical
ISBN : 9788131249994

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Essentials of Neonatal Ventilation, 1st edition, E-book by Rajiv PK,Satyan Lakshminrusimha,Dharmapuri Vidyasagar Pdf

This book is an outstanding attempt to standardize bedside neonatal respiratory care by the most researched authentic experts in the world. This involves more than sixty authors from the United States, the United Kingdom, Canada, Australia, Spain, Italy, Germany, India, UAE, and China. The latest in the arena of neonatal ventilation which holds future promise has been incorporated in this book. The experts take you through a real-time progression of bedside ventilation practices, with the focus on pulmonary and neurological morbidity. The e-book has links to videos of critical chapters and lecture PPTs to give the intensivist a 360-degree understanding of the complexities of neonatal ventilation. First comprehensive bedside management book of a baby on assisted ventilation. Latest evidence-based practices on noninvasive ventilation with protocols. A bedside guide for neonatologists, fellows, residents, postgraduates, medical students, nurse practitioners, and respiratory therapists. Management of assisted ventilation including high-frequency ventilation and NAVA. Analysis and algorithmic approach to cardiac hemodynamics in respiratory distress. Protocolized approaches to critical respiratory diseases of the newborn. Ancillary services explained in detail like targeted ECHO, NIRS, and Graphics by experts. Videos and lecture presentations by experts on SLI, CPAP, SNIPPV, NAVA, ECHO, and Graphics.

Author : Claude Gaultier,Jacques R Bourbon,Martin Post
Publisher : Springer
Page : 464 pages
File Size : 55,8 Mb
Release : 2013-05-27
Category : Medical
ISBN : 9781461475378

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Lung Development by Claude Gaultier,Jacques R Bourbon,Martin Post Pdf

Knowledge about the mechanisms of lung development has been growing rapidly, especially with regard to cellular and molecular aspects of growth and differentiation. This authoritative international volume reviews key aspects of lung development in health and disease by providing a comprehensive review of the complex series of cellular and molecular interactions required for lung development. It covers such topics as pulmonary hypoplasia, effects of malnutrition, and pulmaonary angiogenesis. An indispensable reference for all those involved in studying or treating lung disease in neonates and children, the book offers a unique view of the development of this essential organ.

Author : C. Hugh Tyndale-Biscoe,Marilyn Renfree
Publisher : Cambridge University Press
Page : 496 pages
File Size : 46,5 Mb
Release : 1987-01-30
Category : Nature
ISBN : 0521337925

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Reproductive Physiology of Marsupials by C. Hugh Tyndale-Biscoe,Marilyn Renfree Pdf

The results of this compilation of new research on the reproductive physiology of marsupials reveal much about their patterns of reproduction and evolution in comparison to monotremes and eutherians.