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Author : M. Crane
Publisher : Unknown
Page : 128 pages
File Size : 53,7 Mb
Release : 2001
Category : Electronic
ISBN : OCLC:985780857
Author : Mark Crane,Michael C. Newman,Peter F. Chapman,John S. Fenlon
Publisher : CRC Press
Page : 193 pages
File Size : 52,7 Mb
Release : 2016-04-19
Category : Mathematics
ISBN : 9781420032284
How can environmental regulators use information on 48-hour toxicity tests to predict the effects of a few minutes of pollution? Or, at the other extreme, what is the relevance of 96-hour toxicity data for organisms that may have been exposed to a pollutant for six months or more? Time to event methods are the key to answering these types of questi
Author : Glenn W. Suter II
Publisher : CRC Press
Page : 656 pages
File Size : 48,8 Mb
Release : 2016-04-19
Category : Law
ISBN : 9781420012569
The definitive reference in its field, Ecological Risk Assessment, Second Edition details the latest advances in science and practice. In the fourteen years since the publication of the best-selling first edition, ecological risk assessment (ERA) has moved from the margins into the spotlight. It is now commonly applied to the regulation of c
Author : Mei-Ling Ting Lee,Mitchell Gail,Ruth Pfeiffer,Glen Satten,Tianxi Cai,Axel Gandy
Publisher : Springer Science & Business Media
Page : 445 pages
File Size : 53,9 Mb
Release : 2013-12-11
Category : Medical
ISBN : 9781461489818
Methods of risk analysis and the outcome of particular evaluations and predictions are covered in detail in this proceedings volume, whose contributions are based on invited presentations from Professor Mei-Ling Ting Lee's 2011 symposium on Risk Analysis and the Evaluation of Predictions. This symposium was held at the University of Maryland in October of 2011. Risk analysis is the science of evaluating health, environmental, and engineering risks resulting from past, current, or anticipated, future activities. The use of these evaluations include to provide information for determining regulatory actions to limit risk, present scientific evidence in legal settings, evaluate products and potential liabilities within private organizations, resolve World Trade disputes amongst nations, and educate the public concerning particular risk issues. Risk analysis is an interdisciplinary science that relies on epidemiology and laboratory studies, collection of exposure and other field data, computer modeling, and related social, economic and communication considerations. In addition, social dimensions of risk are addressed by social scientists.
Author : George W. Ware
Publisher : Springer Science & Business Media
Page : 267 pages
File Size : 41,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461212805
Reviews of Environmental Contamination and Toxicology provides detailed review articles concerned with aspects of chemical contaminants, including pesticides, in the total environment with toxicological considerations and consequences.
Author : David M. Whitacre
Publisher : Springer Science & Business Media
Page : 148 pages
File Size : 53,8 Mb
Release : 2008-11-06
Category : Science
ISBN : 9780387098081
Reviews of Environmental Contamination and Toxicology attempts to provide concise, critical reviews of timely advances, philosophy and significant areas of accomplished or needed endeavor in the total field of xenobiotics, in any segment of the environment, as well as toxicological implications.
Author : V.T. Covello,M.W. Merkhoher
Publisher : Springer Science & Business Media
Page : 336 pages
File Size : 55,7 Mb
Release : 1993-12-31
Category : Medical
ISBN : 0306443821
This volume fills the need for a comprehensive guidebook and reference for risk assessment techniques. Within a generalized conceptual framework the authors clarify and integrate basic concepts; critique current methodologies; and teach the selection and application of a specific method and the interpretation of its results. The work makes these seemingly bewildering techniques accessible to readers from all disciplines.
Author : Qi Jiang,Weili He
Publisher : CRC Press
Page : 296 pages
File Size : 41,5 Mb
Release : 2017-12-19
Category : Mathematics
ISBN : 9781482259377
Guides You on the Development and Implementation of B–R Evaluations Benefit–Risk Assessment Methods in Medical Product Development: Bridging Qualitative and Quantitative Assessments provides general guidance and case studies to aid practitioners in selecting specific benefit–risk (B–R) frameworks and quantitative methods. Leading experts from industry, regulatory agencies, and academia present practical examples, lessons learned, and best practices that illustrate how to conduct structured B–R assessment in clinical development and regulatory submission. The first section of the book discusses the role of B–R assessments in medicine development and regulation, the need for both a common B–R framework and patient input into B–R decisions, and future directions. The second section focuses on legislative and regulatory policy initiatives as well as decisions made at the U.S. FDA’s Center for Devices and Radiological Health. The third section examines key elements of B–R evaluations in a product’s life cycle, such as uncertainty evaluation and quantification, quantifying patient B–R trade-off preferences, ways to identify subgroups with the best B–R profiles, and data sources used to assist B–R assessment. The fourth section equips practitioners with tools to conduct B–R evaluations, including assessment methodologies, a quantitative joint modeling and joint evaluation framework, and several visualization tools. The final section presents a rich collection of case studies. With top specialists sharing their in-depth knowledge, thought-provoking considerations, and practical advice, this book offers comprehensive coverage of B–R evaluation methods, tools, and case studies. It gives practitioners a much-needed toolkit to develop and conduct their own B–R evaluations.
Author : E.D. Solozhentsev
Publisher : Springer Science & Business Media
Page : 315 pages
File Size : 44,5 Mb
Release : 2012-04-27
Category : Technology & Engineering
ISBN : 9789400742888
This book presents intellectual, innovative, information technologies (I3-technologies) based on logical and probabilistic (LP) risk models. The technologies presented here consider such models for structurally complex systems and processes with logical links and with random events in economics and technology. The volume describes the following components of risk management technologies: LP-calculus; classes of LP-models of risk and efficiency; procedures for different classes; special software for different classes; examples of applications; methods for the estimation of probabilities of events based on expert information. Also described are a variety of training courses in these topics. The classes of risk models treated here are: LP-modeling, LP-classification, LP-efficiency, and LP-forecasting. Particular attention is paid to LP-models of risk of failure to resolve difficult economic and technical problems. Amongst the discussed procedures of I3-technologies are the construction of LP-models, LP-identification of risk models; LP-risk analysis, LP-management and LP-forecasting of risk. The book further considers LP-models of risk of invalidity of systems and processes in accordance with the requirements of ISO 9001-2008, LP-models of bank operational risks in accordance with the requirements of Basel-2, complex risk LP-models for preventing ammunition depot explosions, enterprise electric power supply systems, debugging tests of technical systems, etc. The book also considers LP-models of credit risks, securities portfolios, operational risks in banking, conteraction of bribes and corruption, etc. A number of applications is given to show the effectiveness of risk management technologies. In addition, topics of lectures and practical computer exercises intended for a two-semester course “Risk management technologies” are suggested.
Author : Vincent James Cogliano,E. Georg Luebeck,Giovanni A. Zapponi
Publisher : Springer Science & Business Media
Page : 329 pages
File Size : 52,9 Mb
Release : 2012-12-06
Category : Technology & Engineering
ISBN : 9781461547419
The first meeting of the NATO/CCMS Pilot Study "Dose-Response Analysis and Biologically-Based Risk assessment for Initiator and Promoter Carcinogens" was held in Rome, Italy, in the spring of 1991, and was followed by annual or bi-annual meetings held in Germany, Greece, Netherlands, Portugal, USA, up to the end of 1995; in large part supported by NATO/CCMS grants or fellowships, and organized by Pilot Study participants. The Pilot Study activity has been characterized by a higly collaborative atmosphere, which was essential for a deep and detailed analysis of a problem on which different points of view, methodological approaches and regulations exist in the various member countries. The Pilot Study was aimed at proposing a carcinogenic risk assessment procedure which is based on a detailed analysis of the relevant biological processes, and may also consent the verification of hypotheses. The specific form of theoretical and mathe matical models is identified by considering and using the whole set of objective data available. The multidisciplinary approach of the pilot study is reflected by the struc ture of this book. Each chapter is the result of the cooperation of several authors from to produce a comprehensive manual that includes different countries; its objective was both theoretical and practical information.
Author : Guillermo R. Chantre,José L. González-Andújar
Publisher : Springer Nature
Page : 341 pages
File Size : 40,7 Mb
Release : 2020-07-31
Category : Technology & Engineering
ISBN : 9783030444020
Weed management Decision Support Systems (DSS) are increasingly important computer-based tools for modern agriculture. Nowadays, extensive agriculture has become highly dependent on external inputs and both economic costs, as well the negative environmental impact of agricultural activities, demands knowledge-based technology for the optimization and protection of non-renewable resources. In this context, weed management strategies should aim to maximize economic profit by preserving and enhancing agricultural systems. Although previous contributions focusing on weed biology and weed management provide valuable insight on many aspects of weed species ecology and practical guides for weed control, no attempts have been made to highlight the forthcoming importance of DSS in weed management. This book is a first attempt to integrate `concepts and practice’ providing a novel guide to the state-of-art of DSS and the future prospects which hopefully would be of interest to higher-level students, academics and professionals in related areas.
Author : Jan Beyersmann,Arthur Allignol,Martin Schumacher
Publisher : Springer Science & Business Media
Page : 249 pages
File Size : 43,9 Mb
Release : 2011-11-18
Category : Mathematics
ISBN : 9781461420354
This book covers competing risks and multistate models, sometimes summarized as event history analysis. These models generalize the analysis of time to a single event (survival analysis) to analysing the timing of distinct terminal events (competing risks) and possible intermediate events (multistate models). Both R and multistate methods are promoted with a focus on nonparametric methods.
Author : W. Kent Muhlbauer
Publisher : Elsevier
Page : 415 pages
File Size : 50,9 Mb
Release : 2004-01-24
Category : Technology & Engineering
ISBN : 9780080497709
Here's the ideal tool if you're looking for a flexible, straightforward analysis system for your everyday design and operations decisions. This new third edition includes sections on stations, geographical information systems, "absolute" versus "relative" risks, and the latest regulatory developments. From design to day-to-day operations and maintenance, this unique volume covers every facet of pipeline risk management, arguably the most important, definitely the most hotly debated, aspect of pipelining today. Now expanded and updated, this widely accepted standard reference guides you in managing the risks involved in pipeline operations. You'll also find ways to create a resource allocation model by linking risk with cost and customize the risk assessment technique to your specific requirements. The clear step-by-step instructions and more than 50 examples make it easy. This edition has been expanded to include offshore pipelines and distribution system pipelines as well as cross-country liquid and gas transmission pipelines. The only comprehensive manual for pipeline risk management Updated material on stations, geographical information systems, "absolute" versus "relative" risks, and the latest regulatory developments Set the standards for global pipeline risk management
Author : Anonim
Publisher : John Wiley & Sons
Page : 2163 pages
File Size : 41,5 Mb
Release : 2008-09-02
Category : Mathematics
ISBN : 9780470035498
Leading the way in this field, the Encyclopedia of Quantitative Risk Analysis and Assessment is the first publication to offer a modern, comprehensive and in-depth resource to the huge variety of disciplines involved. A truly international work, its coverage ranges across risk issues pertinent to life scientists, engineers, policy makers, healthcare professionals, the finance industry, the military and practising statisticians. Drawing on the expertise of world-renowned authors and editors in this field this title provides up-to-date material on drug safety, investment theory, public policy applications, transportation safety, public perception of risk, epidemiological risk, national defence and security, critical infrastructure, and program management. This major publication is easily accessible for all those involved in the field of risk assessment and analysis. For ease-of-use it is available in print and online.
Author : Yacov Y. Haimes
Publisher : John Wiley & Sons
Page : 720 pages
File Size : 52,9 Mb
Release : 2015-07-15
Category : Technology & Engineering
ISBN : 9781119018018
Presents systems-based theory, methodology, and applications in risk modeling, assessment, and management This book examines risk analysis, focusing on quantifying risk and constructing probabilities for real-world decision-making, including engineering, design, technology, institutions, organizations, and policy. The author presents fundamental concepts (hierarchical holographic modeling; state space; decision analysis; multi-objective trade-off analysis) as well as advanced material (extreme events and the partitioned multi-objective risk method; multi-objective decision trees; multi-objective risk impact analysis method; guiding principles in risk analysis); avoids higher mathematics whenever possible; and reinforces the material with examples and case studies. The book will be used in systems engineering, enterprise risk management, engineering management, industrial engineering, civil engineering, and operations research. The fourth edition of Risk Modeling, Assessment, and Management features: Expanded chapters on systems-based guiding principles for risk modeling, planning, assessment, management, and communication; modeling interdependent and interconnected complex systems of systems with phantom system models; and hierarchical holographic modeling An expanded appendix including a Bayesian analysis for the prediction of chemical carcinogenicity, and the Farmer’s Dilemma formulated and solved using a deterministic linear model Updated case studies including a new case study on sequential Pareto-optimal decisions for emergent complex systems of systems A new companion website with over 200 solved exercises that feature risk analysis theories, methodologies, and application Risk Modeling, Assessment, and Management, Fourth Edition, is written for both undergraduate and graduate students in systems engineering and systems management courses. The text also serves as a resource for academic, industry, and government professionals in the fields of homeland and cyber security, healthcare, physical infrastructure systems, engineering, business, and more.