Rna And Rna Modification In The Pathogenesis Diagnosis And Treatment Of Cancers

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Metabolic Abnormalities and Breast Cancer: Challenges From Bench to Bedside

Author : Xiaosong Chen,Mark Daniel Pegram,Pu Li,Zheng Wang
Publisher : Frontiers Media SA
Page : 211 pages
File Size : 47,9 Mb
Release : 2022-08-01
Category : Medical
ISBN : 9782889761876

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Metabolic Abnormalities and Breast Cancer: Challenges From Bench to Bedside by Xiaosong Chen,Mark Daniel Pegram,Pu Li,Zheng Wang Pdf

Translational Medicine in the Diagnosis and Treatment of Cancer based on Oncogenetics: From Bench to Bedside

Author : Changjing Cai,Rui Cao,Jiao Hu,Ying Han,Changsheng Xing
Publisher : Frontiers Media SA
Page : 207 pages
File Size : 47,8 Mb
Release : 2023-12-07
Category : Medical
ISBN : 9782832540121

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Translational Medicine in the Diagnosis and Treatment of Cancer based on Oncogenetics: From Bench to Bedside by Changjing Cai,Rui Cao,Jiao Hu,Ying Han,Changsheng Xing Pdf

Translational medicine was first mentioned in 1992 by Choi D. W and has since become a rapidly expanding area within biomedical research. It is based on the ‘bench to bedside’ approach, which describes it’s relationship between basic science and clinical practice. In 2008, Drs Conway and Dougherty provided a 3 step process to translational medicine and how it should be implemented to transform healthcare systems. The first step is the translation of basic science into clinical research (T1). The second step (T2) focuses on making healthcare more patient specific, basing itself on providing ‘the right treatment for the right patient in the right way at the right time’. T2 also looks for this science to be translated into practice guidelines for clinicians, policy makers and the patients themselves. The final step (T3) addresses the ‘how’ of implementing these ideas, so that high quality healthcare can be delivered reliably to all patients in all settings of care. T3 activities would include policy changes that could serve to bring about meaningful change towards this goal. Cancer is a major public health problem worldwide. Clarifying the etiology and pathogenesis of cancer is of great significance to the prevention, diagnosis, and treatment of the disease. The bench to bedside pattern can be a useful method for cancer-related studies. This Research Topic aims to highlight the emerging role of oncogenetics in cancer, and discuss potential challenges of diagnosis and treatment, from the bench to the bedside.

Molecular Pathogenesis of Colorectal Cancer

Author : Kevin M. Haigis, Ph.D.
Publisher : Springer Science & Business Media
Page : 316 pages
File Size : 40,8 Mb
Release : 2013-10-02
Category : Medical
ISBN : 9781461484127

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Molecular Pathogenesis of Colorectal Cancer by Kevin M. Haigis, Ph.D. Pdf

Colorectal cancer has for more than two decades served as the paradigm for the multi-step concept of cancer initiation and progression. Perhaps more than any other organ site, cancer of the colon is extensively characterized at the molecular level. We are now entering a time when molecular classification, rather than histologic classification, of cancer subtypes is driving the development of clinical trials with emerging targeted therapies. The book will focus on the progression from the identification of mutations that drive colorectal cancer initiation and progression to the search for novel therapies to treat the disease.

Hippocampus

Author : Xinhua Zhang
Publisher : BoD – Books on Demand
Page : 215 pages
File Size : 44,7 Mb
Release : 2022-01-12
Category : Medical
ISBN : 9781839699115

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Hippocampus by Xinhua Zhang Pdf

The hippocampus is a bicortical structure with extensive fiber connections with multiple brain regions. It is involved in several functions, such as learning, memory, attention, emotion, and more. This book covers various aspects of the hippocampus including cytoarchitecture, functions, diseases, and treatment. It highlights the most advanced findings in research on the hippocampus. It discusses circuits, pattern formation process of grid cells, and zinc dynamics of the hippocampus. The book also addresses the tau pathology and circRNAs related to Alzheimer’s disease and potential treatment strategies. It is a useful resource for general readers, students, and researchers.

RNA at a breaking point? cytoplasmic cleavage and other post-transcriptional RNA processing in neurodevelopment and disease

Author : Catia Andreassi,Monika Piwecka,Raphaëlle Luisier
Publisher : Frontiers Media SA
Page : 256 pages
File Size : 50,7 Mb
Release : 2023-06-29
Category : Science
ISBN : 9782832527153

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RNA at a breaking point? cytoplasmic cleavage and other post-transcriptional RNA processing in neurodevelopment and disease by Catia Andreassi,Monika Piwecka,Raphaëlle Luisier Pdf

Identification and Characterization of Molecular Targets in Hepatocellular Carcinoma

Author : Vinay Kumar,Surendra Kumar Shukla
Publisher : Frontiers Media SA
Page : 327 pages
File Size : 49,5 Mb
Release : 2023-07-21
Category : Science
ISBN : 9782832526279

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Identification and Characterization of Molecular Targets in Hepatocellular Carcinoma by Vinay Kumar,Surendra Kumar Shukla Pdf

the field of oncology and is the most common form of liver cancer. In some cases, HCC can be treated through surgery and ablations but can be extended to a full transplant. Risk factors for HCC have been elucidated in previous years, linking hepatitis viruses, diabetes, and alcohol-dependent conditions to the pathogenesis of HCC. Given the prevalence of HCC in global populations (currently >800,000 new cases per year, and rising), there is a requirement to identify molecular targets in HCC and develop new therapeutic strategies to manage and treat HCCs. New technologies and techniques, including gene sequencing, bioinformatics, and liquid biopsy, have helped identify molecular and genetic players involved in the development of HCC. As such, a comprehensive genetic/immune signature of HCC would be invaluable in the development of new therapeutics and treatment strategies, as well as early identification and management of HCC. There are currently various trials that implement a combination of already approved drugs to better the prognosis of patients suffering from HCC. There is, however, still room for improvement, and as our understanding of the various factors involved in HCC improves, so will the prognosis of patients suffering from HCC globally. This Research Topic aims to highlight the molecular and genetic targets that lead to the progression of Hepatocellular Carcinoma. We welcome Original Research, Reviews, and other article types.

Computational Epigenetics and Diseases

Author : Anonim
Publisher : Academic Press
Page : 450 pages
File Size : 40,9 Mb
Release : 2019-02-06
Category : Business & Economics
ISBN : 9780128145142

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Computational Epigenetics and Diseases by Anonim Pdf

Computational Epigenetics and Diseases, written by leading scientists in this evolving field, provides a comprehensive and cutting-edge knowledge of computational epigenetics in human diseases. In particular, the major computational tools, databases, and strategies for computational epigenetics analysis, for example, DNA methylation, histone modifications, microRNA, noncoding RNA, and ceRNA, are summarized, in the context of human diseases. This book discusses bioinformatics methods for epigenetic analysis specifically applied to human conditions such as aging, atherosclerosis, diabetes mellitus, schizophrenia, bipolar disorder, Alzheimer disease, Parkinson disease, liver and autoimmune disorders, and reproductive and respiratory diseases. Additionally, different organ cancers, such as breast, lung, and colon, are discussed. This book is a valuable source for graduate students and researchers in genetics and bioinformatics, and several biomedical field members interested in applying computational epigenetics in their research. Provides a comprehensive and cutting-edge knowledge of computational epigenetics in human diseases Summarizes the major computational tools, databases, and strategies for computational epigenetics analysis, such as DNA methylation, histone modifications, microRNA, noncoding RNA, and ceRNA Covers the major milestones and future directions of computational epigenetics in various kinds of human diseases such as aging, atherosclerosis, diabetes, heart disease, neurological disorders, cancers, blood disorders, liver diseases, reproductive diseases, respiratory diseases, autoimmune diseases, human imprinting disorders, and infectious diseases

lncRNAs in Cancer Metastasis and Therapy Resistance

Author : Aamir Ahmad,Palmiro Poltronieri,Shahab Uddin
Publisher : Frontiers Media SA
Page : 445 pages
File Size : 47,8 Mb
Release : 2023-10-30
Category : Medical
ISBN : 9782832526125

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lncRNAs in Cancer Metastasis and Therapy Resistance by Aamir Ahmad,Palmiro Poltronieri,Shahab Uddin Pdf

lncRNAs (long non-coding RNAs) are the relatively longer (more than 200 nucleotides long) subtypes of ncRNAs (non-coding RNAs) i.e the RNAs that do not code for any proteins. However, even without themselves being translated, lncRNAs impact the cellular gene expressions and functions in ways that are just beginning to be explored. The metastasis of human cancers as well as acquired resistance against the administered therapeutics are two major factors responsible for the cancer-associated mortality.

Epigenetic Regulation in Cancer Immunity

Author : Bo Chen,Chuanzhao Zhang,Zhi Tian,Hailin Tang
Publisher : Frontiers Media SA
Page : 199 pages
File Size : 46,6 Mb
Release : 2023-06-21
Category : Medical
ISBN : 9782832526804

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Epigenetic Regulation in Cancer Immunity by Bo Chen,Chuanzhao Zhang,Zhi Tian,Hailin Tang Pdf

Proteomics and its Applications in Cancer

Author : Suman S. Thakur,Harsha Gowda,D. R. Mani,Bhaswati Chatterjee
Publisher : Frontiers Media SA
Page : 427 pages
File Size : 50,7 Mb
Release : 2022-01-11
Category : Medical
ISBN : 9782889717620

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Proteomics and its Applications in Cancer by Suman S. Thakur,Harsha Gowda,D. R. Mani,Bhaswati Chatterjee Pdf

Identification of Novel Biomarkers for Pancreatic and Hepatocellular Cancers

Author : Brendan Jenkins,Alessandro Passardi,Qingfeng Zhu,Zhaohui Huang
Publisher : Frontiers Media SA
Page : 240 pages
File Size : 48,8 Mb
Release : 2022-12-02
Category : Medical
ISBN : 9782832508367

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Identification of Novel Biomarkers for Pancreatic and Hepatocellular Cancers by Brendan Jenkins,Alessandro Passardi,Qingfeng Zhu,Zhaohui Huang Pdf

Genetic and proteomic biomarkers in solid tumor detection and treatment

Author : Jitian Li,Apeng Chen,Ruowen Zhang,Changwei Li,Jian-Guo Zhou
Publisher : Frontiers Media SA
Page : 862 pages
File Size : 47,7 Mb
Release : 2023-06-07
Category : Science
ISBN : 9782832525456

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Genetic and proteomic biomarkers in solid tumor detection and treatment by Jitian Li,Apeng Chen,Ruowen Zhang,Changwei Li,Jian-Guo Zhou Pdf