Scaffolding In Tissue Engineering

Author : Peter X. Ma,Jennifer Elisseeff
Publisher : CRC Press
Page : 656 pages
File Size : 43,7 Mb
Release : 2005-08-19
Category : Medical
ISBN : 9781420027563

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Scaffolding In Tissue Engineering by Peter X. Ma,Jennifer Elisseeff Pdf

The growing interest in scaffolding design and increasing research programs dedicated to regenerative medicine corroborate the need for Scaffolding in Tissue Engineering. While certain books and journal articles address various aspects in the field, this is the first current, comprehensive text focusing on scaffolding for tissue engineering. Scaffolding in Tissue Engineering reviews the general principles of tissue engineering and concentrates on the principles, methods, and applications for a broad range of tissue engineering scaffolds. The first section presents an in-depth exploration of traditional and novel materials, including alginates, polysaccharides, and fibrillar fibrin gels. The following section covers fabrication technologies, discussing three-dimensional scaffold design, laboratory-scale manufacture of a cell carrier, phase separation, self-assembly, gas foaming, solid freeform fabrication, injectable systems, and immunoisolation techniques. Subsequent chapters examine structural and functional scaffold modification, composite scaffolds, bioactive hydrogels, gene delivery, growth factors, and degradation of biodegradable polymers. The final section explores various tissue engineering applications, comprising chapters on blood cell substitutes, and tissue engineering of nerves, the tendons, ligaments, cornea, cartilage and myocardium, meniscal tissue. While providing a comprehensive summary of current knowledge and technologies, Scaffolding in Tissue Engineering gives readers insight into new trends and directions for scaffold development and for an ever-expanding range of tissue engineering applications.

Author : Claudio Migliaresi,Antonella Motta
Publisher : CRC Press
Page : 698 pages
File Size : 44,5 Mb
Release : 2014-06-10
Category : Medical
ISBN : 9789814463218

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Scaffolds for Tissue Engineering by Claudio Migliaresi,Antonella Motta Pdf

Scaffolds for tissue engineering are devices that exploit specific and complex physical and biological functions, in vitro or in vivo, and communicate through biochemical and physical signals with cells and, when implanted, with the body environment. Scaffolds are produced mainly with synthetic materials, and their fabrication technologies are derived from already well-established industrial processes, with some new specific technologies having been developed in the last years to address required complexities. Often, a generalist approach is followed for the translation of materials and technologies designed for other applications, without considering the specific role of scaffolds from a physical and biological point of view. The book illustrates scaffold design principles, with particular relevance to the biological requirements needed to control and drive the biological cross talk, and reviews materials and fabrication and validation methods.

Author : Paul Tomlins
Publisher : Elsevier
Page : 294 pages
File Size : 55,5 Mb
Release : 2015-10-30
Category : Science
ISBN : 9781782420958

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Characterisation and Design of Tissue Scaffolds by Paul Tomlins Pdf

Characterisation and Design of Tissue Scaffolds offers scientists a useful guide on the characterization of tissue scaffolds, detailing what needs to be measured and why, how such measurements can be made, and addressing industrially important issues. Part one provides readers with information on the fundamental considerations in the characterization of tissue scaffolds, while other sections detail how to prepare tissue scaffolds, discuss techniques in characterization, and present practical considerations for manufacturers. Summarizes concepts and current practice in the characterization and design of tissue scaffolds Discusses design and preparation of scaffolds Details how to prepare tissue scaffolds, discusses techniques in characterization, and presents practical considerations for manufacturers

Author : Gilson Khang
Publisher : CRC Press
Page : 1480 pages
File Size : 51,8 Mb
Release : 2017-06-26
Category : Medical
ISBN : 9789814745130

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Handbook of Intelligent Scaffolds for Tissue Engineering and Regenerative Medicine by Gilson Khang Pdf

Millions of patients suffer from end-stage organ failure or tissue loss annually, and the only solution might be organ and/or tissue transplantation. To avoid poor biocompatibility–related problems and donor organ shortage, however, around 20 years ago a new, hybridized method combining cells and biomaterials was introduced as an alternative to whole-organ and tissue transplantation for diseased, failing, or malfunctioning organs—regenerative medicine and tissue engineering. This handbook focuses on all aspects of intelligent scaffolds, from basic science to industry to clinical applications. Its 10 parts, illustrated throughout with excellent figures, cover stem cell engineering research, drug delivery systems, nanomaterials and nanodevices, and novel and natural biomaterials. The book can be used by advanced undergraduate- and graduate-level students of stem cell and tissue engineering and researchers in macromolecular science, ceramics, metals for biomaterials, nanotechnology, chemistry, biology, and medicine, especially those interested in tissue engineering, stem cell engineering, and regenerative medicine.

Author : Cato T. Laurencin,Lakshmi S. Nair
Publisher : CRC Press
Page : 388 pages
File Size : 44,7 Mb
Release : 2008-06-16
Category : Medical
ISBN : 9781420051834

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Nanotechnology and Tissue Engineering by Cato T. Laurencin,Lakshmi S. Nair Pdf

Nanofabrication gives us the ability to mimic biological structures with molecular level precision. Offering a natural progression of topics, Nanotechnology and Tissue Engineering: The Scaffold provides a state-of-the-art account of groundbreaking research in this rapidly emerging area of biomedical engineering. Emphasizing the importance of scaffo

Author : Peter X. Ma,Jennifer Elisseeff
Publisher : CRC Press
Page : 656 pages
File Size : 42,8 Mb
Release : 2005-08-19
Category : Medical
ISBN : 1574445219

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Scaffolding In Tissue Engineering by Peter X. Ma,Jennifer Elisseeff Pdf

The growing interest in scaffolding design and increasing research programs dedicated to regenerative medicine corroborate the need for Scaffolding in Tissue Engineering. While certain books and journal articles address various aspects in the field, this is the first current, comprehensive text focusing on scaffolding for tissue engineering. Scaffolding in Tissue Engineering reviews the general principles of tissue engineering and concentrates on the principles, methods, and applications for a broad range of tissue engineering scaffolds. The first section presents an in-depth exploration of traditional and novel materials, including alginates, polysaccharides, and fibrillar fibrin gels. The following section covers fabrication technologies, discussing three-dimensional scaffold design, laboratory-scale manufacture of a cell carrier, phase separation, self-assembly, gas foaming, solid freeform fabrication, injectable systems, and immunoisolation techniques. Subsequent chapters examine structural and functional scaffold modification, composite scaffolds, bioactive hydrogels, gene delivery, growth factors, and degradation of biodegradable polymers. The final section explores various tissue engineering applications, comprising chapters on blood cell substitutes, and tissue engineering of nerves, the tendons, ligaments, cornea, cartilage and myocardium, meniscal tissue. While providing a comprehensive summary of current knowledge and technologies, Scaffolding in Tissue Engineering gives readers insight into new trends and directions for scaffold development and for an ever-expanding range of tissue engineering applications.

Author : Claudio Migliaresi,Antonella Motta
Publisher : CRC Press
Page : 701 pages
File Size : 52,9 Mb
Release : 2014-06-10
Category : Medical
ISBN : 9789814463201

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Scaffolds for Tissue Engineering by Claudio Migliaresi,Antonella Motta Pdf

Scaffolds for tissue engineering are devices that exploit specific and complex physical and biological functions, in vitro or in vivo, and communicate through biochemical and physical signals with cells and, when implanted, with the body environment. Scaffolds are produced mainly with synthetic materials, and their fabrication technologies are derived from already well-established industrial processes, with some new specific technologies having been developed in the last years to address required complexities. Often, a generalist approach is followed for the translation of materials and technologies designed for other applications, without considering the specific role of scaffolds from a physical and biological point of view. The book illustrates scaffold design principles, with particular relevance to the biological requirements needed to control and drive the biological cross talk, and reviews materials and fabrication and validation methods.

Author : Ying Deng,Jordan Kuiper
Publisher : Woodhead Publishing
Page : 482 pages
File Size : 54,9 Mb
Release : 2017-10-17
Category : Technology & Engineering
ISBN : 9780081009802

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Functional 3D Tissue Engineering Scaffolds by Ying Deng,Jordan Kuiper Pdf

In order to grow replacement tissues, 3D scaffolds are widely used as a template for tissue engineering and regeneration. These scaffolds, which are typically ‘seeded’ with cells, support the growth of new tissues. However, in order to achieve successful tissue growth, the scaffold must meet specific requirements and are often ‘functionalized’ to accentuate particular properties. Functional 3D tissue engineering scaffolds: materials, technologies, and applications, is a comprehensive review of functional 3D scaffolds, providing information on the fundamentals, technologies, and applications. Part 1 focuses on the fundamentals of 3D tissue scaffolds, examining information on materials, properties, and trends. Part 2 discusses a wide range of conventional technologies for engineering functional 3D scaffolds, leading the way to a discussion on CAD and advanced technologies for functional 3D scaffold engineering. Chapters in part 3 study methods for functionalizing scaffolds to support a variety of in vivo functions whilst the final set of chapters provides an important review of the most significant applications of functional 3D scaffolds within tissue engineering. This book is a valuable resource for biomaterial scientists and biomedical engineers in academia and industry, with interests in tissue engineering and regenerative medicine. Provides a self-contained work for the field of biomaterials and tissue engineering Discusses all the requirements a scaffold must meet and a wide range of strategies to create them Highlights significant and successful applications of functional 3D scaffolds

Author : Anonim
Publisher : CRC Press
Page : 1018 pages
File Size : 55,8 Mb
Release : 2012-02-17
Category : Medical
ISBN : 9789814267861

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Handbook of Intelligent Scaffold for Tissue Engineering and Regenerative Medicine by Anonim Pdf

Providing detailed knowledge about fullerene nanowhiskers and the related low-dimensional fullerene nanomaterials, this book introduces tubular nanofibers made of fullerenes, "fullerene nanotubes," as well as the single crystalline thin film made of C60, called "fullerene nanosheet." It is the first publication featuring the fullerene nanowhiskers made of C60, C70, and C60 derivatives and so forth. It demonstrates the synthetic method (liquid–liquid interfacial precipitation method) and the physical and chemical properties such as electrical, mechanical, optical, magnetic, thermodynamic, and surface properties for the fullerene nanowhiskers, including their electronic device application.

Author : Naznin Sultana,Mohd Izzat Hassan,Mim Mim Lim
Publisher : Springer
Page : 61 pages
File Size : 48,5 Mb
Release : 2014-10-16
Category : Technology & Engineering
ISBN : 9783319097558

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Composite Synthetic Scaffolds for Tissue Engineering and Regenerative Medicine by Naznin Sultana,Mohd Izzat Hassan,Mim Mim Lim Pdf

This book addresses important biomaterials which are commonly used to fabricate scaffolds and it describes two major protocols employed in scaffold fabrication. Tissue engineering or regenerative medicine aims at restoring ex-novo tissues and organs whose functionality has been compromised as a consequence of diseases or traumatic events. The innovative concept underlying tissue engineering is the use of autologous cells, obtained from a biopsy of the patient. Cells are seeded on a porous scaffold which has the role of supporting and guiding cells towards the development of tissue-like structures as well as providing a platform for the delivery under controlled condition of growth factor release, etc. The successful manufacture of scaffolds for tissue engineering applications is crucial. In this book, these biomaterials are discussed. The book also covers illustrated examples, structure and properties of scaffolds, cellular interactions and drug delivery.

Author : Francesco Baino
Publisher : BoD – Books on Demand
Page : 334 pages
File Size : 54,6 Mb
Release : 2017-12-13
Category : Technology & Engineering
ISBN : 9789535136415

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Scaffolds in Tissue EngineeringMaterials, Technologies and Clinical Applications by Francesco Baino Pdf

Biomaterials are often designed to act as scaffolds, i.e., 3D porous templates that support and stimulate the growth of healthy tissue and then safely dissolve once they have performed their functions. This book provides a picture of the current state of the art in the field of scaffolds for tissue engineering, highlighting the potential associated to the latest scientific and technological advancements. The former part of the book focuses on the repair of "hard" tissues (primarily bone) by means of bioceramic/glass scaffolds, and the latter deals with the applications of polymeric scaffolds for regenerating "soft" tissues and structures including the peripheral nerve, heart, gastric mucosa and pancreas. Special emphasis is given to the challenges associated to scaffold manufacturing, biomimetic properties and cell-scaffold interactions.

Author : Masoud Mozafari,Farshid Sefat,Anthony Atala
Publisher : Woodhead Publishing
Page : 874 pages
File Size : 46,5 Mb
Release : 2019-06-15
Category : Technology & Engineering
ISBN : 9780081025628

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Handbook of Tissue Engineering Scaffolds: Volume Two by Masoud Mozafari,Farshid Sefat,Anthony Atala Pdf

Handbook of Tissue Engineering Scaffolds: Volume Two provides a comprehensive and authoritative review on recent advancements in the application and use of composite scaffolds in tissue engineering. Chapters focus on specific tissue/organ (mostly on the structure and anatomy), the materials used for treatment, natural composite scaffolds, synthetic composite scaffolds, fabrication techniques, innovative materials and approaches for scaffolds preparation, host response to the scaffolds, challenges and future perspectives, and more. Bringing all the information together in one major reference, the authors systematically review and summarize recent research findings, thus providing an in-depth understanding of scaffold use in different body systems. Dedicated to the specialist topic of composite scaffolds, featuring all human body systems Covers basic fundamentals and advanced clinical applications Includes up-to-date information on preparation methodology and characterization techniques Highlights clinical data and case studies

Author : Masoud Mozafari,Farshid Sefat,Anthony Atala
Publisher : Woodhead Publishing
Page : 790 pages
File Size : 41,7 Mb
Release : 2019-06-15
Category : Technology & Engineering
ISBN : 9780081025642

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Handbook of Tissue Engineering Scaffolds: Volume One by Masoud Mozafari,Farshid Sefat,Anthony Atala Pdf

Handbook of Tissue Engineering Scaffolds: Volume One, provides a comprehensive and authoritative review on recent advancements in the application and use of composite scaffolds in tissue engineering. Chapters focus on specific tissue/organ (mostly on the structure and anatomy), the materials used for treatment, natural composite scaffolds, synthetic composite scaffolds, fabrication techniques, innovative materials and approaches for scaffolds preparation, host response to the scaffolds, challenges and future perspectives, and more. Bringing all the information together in one major reference, the authors systematically review and summarize recent research findings, thus providing an in-depth understanding of scaffold use in different body systems. Dedicated to the specialist topic of composite scaffolds, featuring all human body systems Covers basic fundamentals and advanced clinical applications Includes up-to-date information on preparation methodology and characterization techniques Highlights clinical data and case studies

Author : Mehdi Razavi
Publisher : Bentham Science Publishers
Page : 308 pages
File Size : 54,5 Mb
Release : 2017-10-03
Category : Science
ISBN : 9781681085364

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Biomaterials for Tissue Engineering by Mehdi Razavi Pdf

This volume reviews the published knowledge about bioactive composites, protein scaffolds and hydrogels. Chapters also detail the production parameters and clarify the evaluation protocol for analysis or testing and scaffolding biomaterials. The volume concludes with a summary of applications of porous scaffold in medicine. Each chapter links basic scientific and engineering concepts to practical applications for the benefit of the reader. The text offers a wealth of information that will be of use to all students, bioengineers, materials scientists, chemists, physicians and surgeons concerned with the properties, performance, and the application of tissue engineering scaffolds in clinical settings.

Author : Naznin Sultana,Mohd Izzat Hassan,M. I. M. Mim Lim
Publisher : Unknown
Page : 72 pages
File Size : 54,9 Mb
Release : 2014-11-30
Category : Electronic
ISBN : 3319097563

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Composite Synthetic Scaffolds for Tissue Engineering and Regenerative Medicine by Naznin Sultana,Mohd Izzat Hassan,M. I. M. Mim Lim Pdf