Scaling Chemical Processes

Author : Jonathan Worstell
Publisher : Butterworth-Heinemann
Page : 186 pages
File Size : 55,8 Mb
Release : 2016-10-27
Category : Technology & Engineering
ISBN : 9780128047699

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Scaling Chemical Processes by Jonathan Worstell Pdf

Scaling Chemical Processes: Practical Guides in Chemical Engineering is one of a series of short texts that each provides a focused introductory view on a single subject. The full library spans the main topics in the chemical process industries for engineering professionals who require a basic grounding in various related topics. They are ‘pocket publications’ that the professional engineer can easily carry with them or access electronically while working. Each text is highly practical and applied, and presents first principles for engineers who need to get up to speed in a new area fast. The focused facts provided in each guide will help you converse with experts in the field, attempt your own initial troubleshooting, check calculations, and solve rudimentary problems. This book discusses scaling chemical processes from a laboratory through a pilot plant to a commercial plant. It bases scaling on similarity principles and uses dimensional analysis to derive the dimensionless parameters necessary to ensure a successful chemical process development program. This series is fully endorsed and co-branded by the IChemE, and they help to promote the series. Offers practical, short, concise information on the basics to help you get an answer or teach yourself a new topic quickly Includes industry examples to help you solve real world problems Provides key facts for professionals in convenient single subject volumes Discusses scaling chemical processes from a laboratory through a pilot plant to a commercial plant

Author : Jean-Paul Euzen,Pierre Trambouze,Jean-Pierre Wauquier
Publisher : Editions TECHNIP
Page : 266 pages
File Size : 44,5 Mb
Release : 1993
Category : Science
ISBN : 2710806460

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Scale-up Methodology for Chemical Processes by Jean-Paul Euzen,Pierre Trambouze,Jean-Pierre Wauquier Pdf

Having gained considerable experience in process development at the Institut FranCais du PEtrole, the authors present a design framework, a review of the available means of investigation, and several examples illustrating their methodology of industrial process scale up. The salient feature of the book is the fact that it addresses a subject which is vital in view of its economic repercussions, yet relatively unknown in technical and scientific circles, due to the confidentiality surrounding it.Contents: 1. Main guidelines of the methodology. 2. Various types of model. 3. Pilot plants and mock-ups. 4. Experimental techniques. 5. Applications to industrial process development. 6. Conclusions. References. Index.

Author : Attilio Bisio,Robert L. Kabel
Publisher : Wiley-Interscience
Page : 760 pages
File Size : 52,5 Mb
Release : 1985-07-25
Category : Science
ISBN : UOM:39015010893249

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Scaleup of Chemical Processes by Attilio Bisio,Robert L. Kabel Pdf

The focus of this book is on the technical factors that are critical to th e design and startup of a commercial manufacturing facility.

Author : Marko Zlokarnik
Publisher : Springer Science & Business Media
Page : 187 pages
File Size : 43,5 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642766732

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Dimensional Analysis and Scale-up in Chemical Engineering by Marko Zlokarnik Pdf

Contemporary Chemical Process Engineers face complex design and research problems. Temperature-dependent physical properties and non-Newtonian flow behavior of substances in a process cannot be predicted by numerical mathematics. Scaling-up equipment for processing can often only be done with partial similarity methods. Standard textbooks often neglect topics like dimensional analysis, theory of similarity and scale-up. This book fills this gap! It is aimed both at university students and the process engineer. It presents dimensional analysis very comprehensively with illustrative examples of mechanical, thermal and chemical processes.

Author : Marko Zlokarnik
Publisher : John Wiley & Sons
Page : 296 pages
File Size : 47,6 Mb
Release : 2006-08-21
Category : Science
ISBN : 9783527607761

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Scale-up in Chemical Engineering by Marko Zlokarnik Pdf

Covering the important task of the scale-up of processes from the laboratory to the production scale, this easily comprehensible and transparent book is divided into two sections. The first part details the theoretical principles, introducing the subject for readers without a profound prior knowledge of mathematics. It discusses the fundamentals of dimensional analysis, the treatment of temperature-dependent and rheological material values and scale-up where model systems or not available or only partly similar. All this is illustrated by 20 real-world examples, while 25 exercises plus solutions new to this edition practice and monitor learning. The second part presents the individual basic operations and covers the fields of mechanical, thermal, and chemical process engineering with respect to dimensional analysis and scale-up. The rules for scale-up are given and discussed for each operation. Other additions to this second edition are dimensional analysis of pelleting processes, and a historical overview of dimensional analysis and modeling, while all the chapters have been updated to take the latest literature into account. Written by a specialist with more than 40 years of experience in the industry, this book is specifically aimed at students as well as practicing engineers, chemists and process engineers already working in the field.

Author : Jamal Chaouki,Rahmat Sotudeh-Gharebagh
Publisher : Walter de Gruyter GmbH & Co KG
Page : 350 pages
File Size : 52,7 Mb
Release : 2021-09-20
Category : Technology & Engineering
ISBN : 9783110713985

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Scale-Up Processes by Jamal Chaouki,Rahmat Sotudeh-Gharebagh Pdf

Common scale-up methods are conventional where the blind piloting is essential. This imposes huge investment and leads to failures mostly in solid processing. However, the limitations of resources, current shortcomings, short time-to-market demand are forced companies to minimize piloting. With these situations in mind, current digitalization outlook and computational facilities, we proposed and developed a novel iterative scale up method with case studies which highly expedites the process innovation through the following key sequences:

Author : Jamal Chaouki,Rahmat Sotudeh-Gharebagh
Publisher : Walter de Gruyter GmbH & Co KG
Page : 407 pages
File Size : 46,7 Mb
Release : 2021-09-20
Category : Technology & Engineering
ISBN : 9783110714135

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Scale-Up Processes by Jamal Chaouki,Rahmat Sotudeh-Gharebagh Pdf

Common scale-up methods are conventional where the blind piloting is essential. This imposes huge investment and leads to failures mostly in solid processing. However, the limitations of resources, current shortcomings, short time-to-market demand are forced companies to minimize piloting. With these situations in mind, current digitalization outlook and computational facilities, we proposed and developed a novel iterative scale up method with case studies which highly expedites the process innovation through the following key sequences:

Author : William Hoyle
Publisher : Royal Society of Chemistry
Page : 120 pages
File Size : 53,7 Mb
Release : 1997
Category : Science
ISBN : UOM:39015041019434

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Pilot Plants and Scale-up of Chemical Processes by William Hoyle Pdf

One of the biggest challenges facing today's chemist and chemical engineer is the translation of bench chemistry to the pilot plant. This book provides expert insights into current best practice, and will prove an indispensable manual for all those involved in pilot plant design and scale-up implementation - process chemists, engineers and managers alike. The international expertise of the contributors covers a wide range of topics, and new material covered includes: the removal of heavy metals from effluent, heat flow calorimetry, low temperature processes, good manufacturing practice in pilot plants, design issues, the use of statistical methods in the running of pilot plants. Pilot Plants and Scale-Up of Chemical Processes is a must for all those who are, and wish to remain, expert in the field, providing for the first time in print, a comprehensive and unique perspective of pilot plant production.

Author : William Hoyle
Publisher : Unknown
Page : 136 pages
File Size : 45,5 Mb
Release : 1999
Category : Science
ISBN : UOM:39015048550134

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Pilot Plants and Scale-up of Chemical Processes II by William Hoyle Pdf

Presents seven papers from an October 1998 symposium, of interest to those responsible for translating bench chemistry up to 10-100 liter pilot plants and for those responsible for operating such pilot plants. Looks at productivity, particularly in relation to batch processing and meeting the threat from overseas manufacturing, and details a collaboration project between industry and academia in the UK. Discusses chemical aspects of scale-up, the use of phase transfer catalysis, control of crystallization, and scale-up of organo-lithium and Grignard reactions. Safety concepts are also covered. Annotation copyrighted by Book News, Inc., Portland, OR

Author : Donald G. Jordan
Publisher : Unknown
Page : 648 pages
File Size : 48,9 Mb
Release : 1968
Category : Chemical engineering
ISBN : UCAL:B4125856

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Chemical Process Development by Donald G. Jordan Pdf

Author : Mary T. am Ende,David J. am Ende
Publisher : John Wiley & Sons
Page : 1435 pages
File Size : 47,5 Mb
Release : 2019-04-08
Category : Technology & Engineering
ISBN : 9781119285502

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Chemical Engineering in the Pharmaceutical Industry by Mary T. am Ende,David J. am Ende Pdf

A guide to the important chemical engineering concepts for the development of new drugs, revised second edition The revised and updated second edition of Chemical Engineering in the Pharmaceutical Industry offers a guide to the experimental and computational methods related to drug product design and development. The second edition has been greatly expanded and covers a range of topics related to formulation design and process development of drug products. The authors review basic analytics for quantitation of drug product quality attributes, such as potency, purity, content uniformity, and dissolution, that are addressed with consideration of the applied statistics, process analytical technology, and process control. The 2nd Edition is divided into two separate books: 1) Active Pharmaceutical Ingredients (API’s) and 2) Drug Product Design, Development and Modeling. The contributors explore technology transfer and scale-up of batch processes that are exemplified experimentally and computationally. Written for engineers working in the field, the book examines in-silico process modeling tools that streamline experimental screening approaches. In addition, the authors discuss the emerging field of continuous drug product manufacturing. This revised second edition: Contains 21 new or revised chapters, including chapters on quality by design, computational approaches for drug product modeling, process design with PAT and process control, engineering challenges and solutions Covers chemistry and engineering activities related to dosage form design, and process development, and scale-up Offers analytical methods and applied statistics that highlight drug product quality attributes as design features Presents updated and new example calculations and associated solutions Includes contributions from leading experts in the field Written for pharmaceutical engineers, chemical engineers, undergraduate and graduation students, and professionals in the field of pharmaceutical sciences and manufacturing, Chemical Engineering in the Pharmaceutical Industry, Second Edition contains information designed to be of use from the engineer's perspective and spans information from solid to semi-solid to lyophilized drug products.

Author : William B. Krantz
Publisher : John Wiley & Sons
Page : 576 pages
File Size : 42,7 Mb
Release : 2007-06-04
Category : Technology & Engineering
ISBN : 9780470121924

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Scaling Analysis in Modeling Transport and Reaction Processes by William B. Krantz Pdf

This book is unique as the first effort to expound on the subject of systematic scaling analysis. Not written for a specific discipline, the book targets any reader interested in transport phenomena and reaction processes. The book is logically divided into chapters on the use of systematic scaling analysis in fluid dynamics, heat transfer, mass transfer, and reaction processes. An integrating chapter is included that considers more complex problems involving combined transport phenomena. Each chapter includes several problems that are explained in considerable detail. These are followed by several worked examples for which the general outline for the scaling is given. Each chapter also includes many practice problems. This book is based on recognizing the value of systematic scaling analysis as a pedagogical method for teaching transport and reaction processes and as a research tool for developing and solving models and in designing experiments. Thus, the book can serve as both a textbook and a reference book.

Author : Jacob A. Moulijn,Michiel Makkee,Annelies E. van Diepen
Publisher : Wiley-Blackwell
Page : 480 pages
File Size : 50,9 Mb
Release : 2001-06-04
Category : Science
ISBN : UOM:39015050472383

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Chemical Process Technology by Jacob A. Moulijn,Michiel Makkee,Annelies E. van Diepen Pdf

Providing an essential bridge between chemistry and the chemical industry, this text focuses on chemical reactions and the reactor since this is at the heart of each process.

Author : Richard Turton,Richard C. Bailie,Wallace B. Whiting,Joseph A. Shaeiwitz
Publisher : Pearson Education
Page : 1562 pages
File Size : 50,5 Mb
Release : 2008-12-24
Category : Technology & Engineering
ISBN : 9780132459181

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Analysis, Synthesis and Design of Chemical Processes by Richard Turton,Richard C. Bailie,Wallace B. Whiting,Joseph A. Shaeiwitz Pdf

The Leading Integrated Chemical Process Design Guide: Now with New Problems, New Projects, and More More than ever, effective design is the focal point of sound chemical engineering. Analysis, Synthesis, and Design of Chemical Processes, Third Edition, presents design as a creative process that integrates both the big picture and the small details–and knows which to stress when, and why. Realistic from start to finish, this book moves readers beyond classroom exercises into open-ended, real-world process problem solving. The authors introduce integrated techniques for every facet of the discipline, from finance to operations, new plant design to existing process optimization. This fully updated Third Edition presents entirely new problems at the end of every chapter. It also adds extensive coverage of batch process design, including realistic examples of equipment sizing for batch sequencing; batch scheduling for multi-product plants; improving production via intermediate storage and parallel equipment; and new optimization techniques specifically for batch processes. Coverage includes Conceptualizing and analyzing chemical processes: flow diagrams, tracing, process conditions, and more Chemical process economics: analyzing capital and manufacturing costs, and predicting or assessing profitability Synthesizing and optimizing chemical processing: experience-based principles, BFD/PFD, simulations, and more Analyzing process performance via I/O models, performance curves, and other tools Process troubleshooting and “debottlenecking” Chemical engineering design and society: ethics, professionalism, health, safety, and new “green engineering” techniques Participating successfully in chemical engineering design teams Analysis, Synthesis, and Design of Chemical Processes, Third Edition, draws on nearly 35 years of innovative chemical engineering instruction at West Virginia University. It includes suggested curricula for both single-semester and year-long design courses; case studies and design projects with practical applications; and appendixes with current equipment cost data and preliminary design information for eleven chemical processes–including seven brand new to this edition.

Author : Robert Edgeworth Johnstone,Meredith Wooldridge Thring
Publisher : Unknown
Page : 332 pages
File Size : 42,6 Mb
Release : 1957
Category : Technology & Engineering
ISBN : UOM:39015006049459

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Pilot Plants, Models, and Scale-up Methods in Chemical Engineering by Robert Edgeworth Johnstone,Meredith Wooldridge Thring Pdf