Science Of Synthesis Flow Chemistry In Organic Synthesis

Author : T.F. Jamison,G. Koch
Publisher : Thieme
Page : 932 pages
File Size : 55,8 Mb
Release : 2018-12-12
Category : Science
ISBN : 9783132423343

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Science of Synthesis: Flow Chemistry in Organic Synthesis by T.F. Jamison,G. Koch Pdf

The aim of this work is to convey the practice, power, and potential of flow chemistry to a larger audience. An emerging and strengthening trend is that flow chemistry is much more than the adaption of batch processes to flow systems. Rather, flow chemistry offers a new paradigm in the way we think about chemical synthesis. This volume demonstrates the enabling power of continuous flow to access new reaction types and different chemistry space and, to this end, it has been compiled by a team of pioneers and leaders, who present both the practical and conceptual aspects of this rapidly growing field. Included are the principles of reactor design, automation, and separations/purifications in flow systems, applications in photochemistry, electrochemistry, gaseous systems, immobilized reagents and catalysts, and multistep processes. The synthesis of peptides, carbohydrates, and pharmaceuticals is covered and several chapters give insight into the use of flow in an industrial context.

Author : F. Serratosa,J. Xicart
Publisher : Elsevier
Page : 539 pages
File Size : 41,7 Mb
Release : 1996-05-09
Category : Science
ISBN : 0080538142

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Organic Chemistry in Action by F. Serratosa,J. Xicart Pdf

The first edition of this book was welcomed with great enthusiasm by teachers and students. It therefore seemed opportune to publish a second, revised, updated and extended edition. Unfortunately, Professor Fèlix Serratosa died before he could complete this task. Some new material has been added, the more significant changes being:. The book has been restructured into two well-differentiated sections: Part A, dealing with conventional organic synthesis, and Part B, devoted exclusively to computer-assisted organic synthesis and based on the former Chapter 11 and Appendices 2, 3 and 4 of the first edition. As decided in advance, Part B was to be the sole responsibility of Dr. Josep Xicart, who prepared the first versions of the CHAOS (Computerisation and Heuristics Applied to Organic Synthesis) program under the direction of Professor Serratosa.

Author : Charlotte Wiles,Paul Watts
Publisher : CRC Press
Page : 453 pages
File Size : 44,5 Mb
Release : 2016-04-19
Category : Science
ISBN : 9781439824726

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Micro Reaction Technology in Organic Synthesis by Charlotte Wiles,Paul Watts Pdf

While continuous processes have found widespread application within chemical production, members of the research and development communities have historically favored the centuries old technique of iterative batch reactions. With the exception of combinatorial and microwave chemistry, little had been done to change the way that synthetic chemists c

Author : Douglass F. Taber,Tristan Lambert
Publisher : Oxford University Press
Page : 280 pages
File Size : 44,6 Mb
Release : 2017-10-20
Category : Science
ISBN : 9780190646172

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Organic Synthesis by Douglass F. Taber,Tristan Lambert Pdf

Organic synthesis is a vibrant and rapidly evolving field; chemists can now cyclize alkenes directly onto enones. Like the first five books in this series, Organic Synthesis: State of the Art 2013-2015 will lead readers quickly to the most important recent developments in a research area. This series offers chemists a way to stay abreast of what's new and exciting in organic synthesis. The cumulative reaction/transformation index of 2013-2015 outlines all significant new organic transformations over the past twelve years. Future volumes will continue to come out every two years. The 2013-2015 volume features the best new methods in subspecialties such as C-O, C-N and C-C ring construction, catalytic asymmetric synthesis, selective C-H functionalization, and enantioselective epoxidation. This text consolidates two years of Douglass Taber's popular weekly online column, "Organic Chemistry Highlights" as featured on the organic-chemistry.org website and also features cumulative indices of all six volumes in this series, going back twelve years.

Author : Toma Glasnov
Publisher : Springer
Page : 119 pages
File Size : 42,9 Mb
Release : 2016-06-01
Category : Science
ISBN : 9783319321967

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Continuous-Flow Chemistry in the Research Laboratory by Toma Glasnov Pdf

This book presents a short introduction to the historical background to the field, the state of the art and a brief survey of the available instrumentation and the processing techniques used. The following major areas of interest in synthetic, organic and medicinal chemistry are elaborated on: transition-metal catalyzed reactions, organocatalytic transformations, heterocyclic synthesis, and photochemical reactions. Finally, selected applications in industry are also discussed. With its ample presentation of examples from recent literature, this is an essential and reliable source of information for both experienced researchers and postgraduate newcomers to the field.

Author : Koichi Fukase,Takayuki Doi
Publisher : Springer Nature
Page : 357 pages
File Size : 47,9 Mb
Release : 2021-07-13
Category : Science
ISBN : 9789811624582

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Middle Molecular Strategy by Koichi Fukase,Takayuki Doi Pdf

This book highlights recently discovered aspects of “middle-size molecules,” focusing on (1) their unique bio-functions on the basis of derivatives and conjugates of natural products, saccharides, peptides, and nucleotides; (2) the synthesis of structurally complex natural products; (3) special synthetic methods for π-conjugated functional molecules; and (4) novel synthetic methods using flow chemistry. Given its scope, the book is of interest to industrial researchers and graduate students in the fields of organic chemistry, medicinal chemistry, and materials science.

Author : Upendra K. Sharma,Erik V. Van der Eycken
Publisher : Springer
Page : 397 pages
File Size : 47,9 Mb
Release : 2018-06-20
Category : Science
ISBN : 9783319943282

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Flow Chemistry for the Synthesis of Heterocycles by Upendra K. Sharma,Erik V. Van der Eycken Pdf

This volume provides an overview of recent developments and scope in the use of flow chemistry in relevance to heterocyclic synthesis. The heterocyclic ring is the most prominent structural motif in the vast majority of natural products as well as pharmaceutical compounds since this facilitates tuneable interactions with the biological target besides conferring a degree of structural and metabolic stability. In recent times, flow chemistry has heralded a paradigm shift in organic synthesis as it offers several unique advantages over conventional methods like drastic acceleration of sluggish transformations, enhanced yields, cleaner reactions etc and is gradually gaining a lot of attention among organic chemist worldwide. Given the importance of heterocycles in natural products, medicinal chemistry and pharmaceuticals, this is a well warranted volume and complements the previous volume of Topics in Organometallic Chemistry ‘Organometallic Flow Chemistry’. This volume offers a versatile overview of the topic, besides discussing the recent progress in the flourishing area of flow chemistry in relevance to heterocyclic chemistry; it will also help researchers to better understand the chemistry behind these reactions. This in turn provides a platform for future innovations towards the designing of novel transformations under continuous flow. Thus, this volume will appeal to both the novices in this field as well as to experts in academia and industry.

Author : Ferenc Darvas,Volker Hessel,György Dorman
Publisher : Walter de Gruyter GmbH & Co KG
Page : 313 pages
File Size : 42,8 Mb
Release : 2014-08-25
Category : Technology & Engineering
ISBN : 9783110388756

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Fundamentals by Ferenc Darvas,Volker Hessel,György Dorman Pdf

"Flow Chemistry fills the gap in graduate education by covering chemistry and reaction principles along with current practice, including examples of relevant commercial reaction, separation, automation, and analytical equipment. The Editors of Flow Chemistry are commended for having taken the initiative to bring together experts from the field to provide a comprehensive treatment of fundamental and practical considerations underlying flow chemistry. It promises to become a useful study text and as well as reference for the graduate students and practitioners of flow chemistry." Professor Klavs Jensen Massachusetts Institute of Technology, USA Broader theoretical insight in driving a chemical reaction automatically opens the window towards new technologies particularly to flow chemistry. This emerging concept promotes the transformation of present day's organic processes into a more rapid continuous set of synthesis operations, more compatible with the envisioned sustainable world. These two volumes Fundamentals and Applications provide both the theoretical foundation as well as the practical aspects.

Author : Kilian Muñiz
Publisher : Thieme
Page : 1425 pages
File Size : 47,8 Mb
Release : 2018-03-23
Category : Science
ISBN : 9783132012714

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Science of Synthesis: Catalytic Oxidation in Organic Synthesis by Kilian Muñiz Pdf

The development of catalytic systems for the oxidation of organic compounds continues to be of great importance. There is an ongoing and increasing demand for methods that are selective, proceed under mild conditions, and adhere to green chemistry principles. "Science of Synthesis: Catalytic Oxidation in Organic Synthesis" includes the latest developments in the field, as well as selective coverage of more well-established methods. Systems based on metal catalysts, organocatalysts, and biomimetic oxidation are covered, and there is a particular focus on asymmetric processes. Scope, limitations, and mechanism of the reactions are discussed and key experimental procedures are included. Typical examples of target synthesis are often provided to show the utility and inspire further applications.

Author : Ferenc Darvas,György Dormán,Volker Hessel,Steven V. Ley
Publisher : Walter de Gruyter GmbH & Co KG
Page : 568 pages
File Size : 51,9 Mb
Release : 2021-10-25
Category : Technology & Engineering
ISBN : 9783110693775

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Flow Chemistry – Fundamentals by Ferenc Darvas,György Dormán,Volker Hessel,Steven V. Ley Pdf

The fully up-dated edition of the two-volume work covers both the theoretical foundation as well as the practical aspects. Presenting the complete insight into driving a chemical reaction provides a deep understanding for new potential technologies. Updated overview on devices and new key concepts of experimental procedures. Vol. 2: Applications.

Author : Barry M. Trost
Publisher : Elsevier
Page : 1328 pages
File Size : 54,5 Mb
Release : 1991
Category : Science
ISBN : 0080405959

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Comprehensive Organic Synthesis: Additions to and substitutions at C-C[pi]-Bonds by Barry M. Trost Pdf

Volume 4 focuses on additions and the resulting substitutions at carbon-carbon &pgr;-bonds. Part 1 includes processes generally considered as simple polar reactions, reactive electrophiles and nucleophiles adding to alkenes and alkynes. A major topic is Michael-type addition to electron deficient &pgr;-bonds, featured in the first six chapters. In part 2 are collected the four general processes leading to nucleophilic aromatic substitution, including radical chain processes and transition metal activation through to &pgr;-complexation. Metal-activated addition (generally by nucleophiles) to alkenes and polyenes is presented in part 3, including allylic alkylation catalyzed by palladium. The coverage of nonpolar additions in part 4 includes radical additions, organometal addition (Heck reaction), carbene addition, and 1,3-dipolar cycloadditions.

Author : Barry M. Trost
Publisher : Unknown
Page : 128 pages
File Size : 44,9 Mb
Release : 1991
Category : Electronic
ISBN : OCLC:634143513

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Comprehensive Organic Synthesis by Barry M. Trost Pdf

Author : Di Qiu,Jianbo Wang
Publisher : World Scientific
Page : 533 pages
File Size : 51,8 Mb
Release : 2020-12-29
Category : Science
ISBN : 9781786348913

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Recent Developments Of Diazo Compounds In Organic Synthesis by Di Qiu,Jianbo Wang Pdf

Diazo compounds are versatile substances with diverse transformations in organic synthesis and other fields. Studies of diazo compounds have been ongoing for a very long time but still attract significant attention within the organic chemistry community, with new papers related to diazo compounds appearing at a daily pace. Over the past twenty years, there have been over fifty reviews and accounts related to the reactions of diazo compounds, but most of them cover limited aspects of diazo compounds. In addition to organic synthesis, diazo compounds have found applications in interdisciplinary fields such as material sciences, chemical biology and also polymerization.In this comprehensive book, the authors cover the most recent advances in the fields related to diazo compounds, including the application of donor-acceptor carbenes, carbene-based cross-coupling reactions and polymerizations, as well as the breakthrough in catalytic asymmetric carbene O-H, S-H, and N-H bond insertions. They also cover the application of flow chemistry in diazo reactions. The authors aim to provide a contemporary and comprehensive review for investigators engaged in or with interest in diazo compounds to boost further developments in this fascinating field.

Author : L. Ackermann
Publisher : Thieme
Page : 574 pages
File Size : 55,9 Mb
Release : 2021-12-10
Category : Science
ISBN : 9783132442139

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Science of Synthesis: Electrochemistry in Organic Synthesis by L. Ackermann Pdf

Applications of Electrochemistry in Synthesis Electrosynthesis represents an increasingly viable platform for molecular synthesis, which is currently undergoing a remarkable renaissance. The use of electricity can, for instance, avoid chemical redox reagents as well as the generation of byproducts derived thereof, setting the stage for improved resource economy. This volume is the defining reference work for this rapidly evolving research arena. It features a collection of the most practical and robust methods of organic electrosynthesis. It introduces the key concepts of electrochemistry and provides all relevant laboratory set-ups, enabling newcomers to the field the effective application of these powerful new tools to molecular syntheses. Innovative strategies that successfully realize topical challenging transformations by the art of electrosynthesis are presented. Pioneers and leaders in the field discuss both the practical and conceptual aspects of this rapidly evolving research field.

Author : Timothy Noël
Publisher : Springer
Page : 267 pages
File Size : 42,8 Mb
Release : 2016-04-22
Category : Science
ISBN : 9783319332437

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Organometallic Flow Chemistry by Timothy Noël Pdf

The series Topics in Organometallic Chemistry presents critical overviews of research results in organometallic chemistry. As our understanding of organometallic structure, properties and mechanisms increases, new ways are opened for the design of organometallic compounds and reactions tailored to the needs of such diverse areas as organic synthesis, medical research, biology and materials science. Thus the scope of coverage includes a broad range of topics of pure and applied organometallic chemistry, where new breakthroughs are being achieved that are of significance to a larger scientific audience. The individual volumes of Topics in Organometallic Chemistry are thematic. Review articles are generally invited by the volume editors. All chapters from Topics in Organometallic Chemistry are published OnlineFirst with an individual DOI. In references, Topics in Organometallic Chemistry is abbreviated as Top Organomet Chem and cited as a journal