Selected Organic Syntheses

Author : Ian Fleming
Publisher : John Wiley & Sons
Page : 248 pages
File Size : 43,6 Mb
Release : 1973
Category : Science
ISBN : UOM:39015018153620

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Selected Organic Syntheses by Ian Fleming Pdf

1. Synthesis 1; 2. Synthesis in the nineteenth century 7; 3. Tropinone and cocaine 17; 4. Cyclooctatetraene 24; 5. Callistephin chloride 26; 6. Thyroxine 30; 7. Ascorbic acid 34; 8. Mesoporhyrin-IX and haemin 40; 9. Morphine 50; 10. Cholesterol and cortisone 57; 11. Cycloartenol 66; 12. ß-Carotene 70; 13. Dehydroabietic acid 75; 14. The penicillins 80; 15. Cephalosporin C 85; 16. Coenzyme A 92; 17. Peptide synthesis: bradykinin 98; 18. Chlorophyll-a 112; 19. Patchouli alcohol 125; 20. A steroid synthesis or an industrial scale 130; 21. Caryophyllene 137; 22. [18]Annulene 141; 23. Cyclobutadiene 144; 24. Adamantanes 149; 25. Cyclopropanones 153; 26. A third steroid synthesis 156; 27. Cecropia juvenile hormone 165; 28. A second synthesis of the cecropia juvenile hormone 171; 29. Lycopodine 176; 30. Colchicine (first synthesis) 183; 31. Colchicine (second synthesis) 193; 32. Colchicine (third synthesis) 198; 33. Colchicine (fourth synthesis) 202; 34 prostaglandins F2[alpha] and E2 208; 35. reserpine 214.

Author : Anonim
Publisher : Unknown
Page : 128 pages
File Size : 52,5 Mb
Release : 2024-07-02
Category : Electronic
ISBN : 9789814464567

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Organic Synthesis via Examination of Selected Natural Products by Anonim Pdf

Author : Stuart Warren
Publisher : John Wiley & Sons
Page : 298 pages
File Size : 44,5 Mb
Release : 1991-01-08
Category : Science
ISBN : 0471996122

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Designing Organic Syntheses by Stuart Warren Pdf

Teaches students to use the language of sythesis directly (utilizing the grammar of synthon and disconnection) rather than translating it into that of organic chemistry.

Author : Anthony W. Czarnik
Publisher : Wiley-Interscience
Page : 184 pages
File Size : 46,5 Mb
Release : 2001-02-26
Category : Mathematics
ISBN : UOM:39015053381326

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Solid-Phase Organic Syntheses by Anthony W. Czarnik Pdf

The rapid expansion of combinatorial chemistry has renewed interest in solid-phase organic synthesis, a method that lends itself well to creating and screening large numbers of lead compounds. Solid-Phase Organic Syntheses, Volume 1 is the first volume in a series that will be updated annually, filling a gap in the existing chemical literature. Providing information previously unavailable from a single resource, this series is dedicated to providing researchers in the field with validated and tested methods for the solid-phase synthesis of interesting and biologically relevant molecules. Solid-phase methods will virtually always be invented for application in combinatorial organic synthesis. To meet these specific needs, Solid-Phase Organic Syntheses, Volume 1 focuses on a single type of synthetic transformation accomplished on solid support, and indicates how procedures are optimized to work with a structurally-wide variety of reagents. Written by recognized leaders in the field who review and test all chemical protocols before publication, organic transformations are organized by type of compound synthesized and reaction type. For the first time, experimental details for proven solid-phase synthetic molecules are collected in a single, invaluable resource. Solid-Phase Organic Syntheses, Volume 1 provides combinatorial chemists and researchers in organic chemistry and medicinal chemistry with the tools and descriptive protocols to achieve syntheses of desired compounds using a variety of solid supports and reagents.

Author : Alfred Hassner,C Stumer
Publisher : Elsevier
Page : 462 pages
File Size : 54,8 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483287348

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Organic Syntheses Based on Name Reactions and Unnamed Reactions by Alfred Hassner,C Stumer Pdf

Synthetically useful organic reactions or reagents are often referred to by the name of the discoverer(s) or developer(s). Older name reactions are described in text books, but more recently developed synthetically useful reactions that may have been associated occasionally with a name are not always well known. For neither of the above are experimental procedures or references easy to find. In this monograph approximately 500 name reactions are included, of which over 200 represent newer name reactions and modern reagents. Each of these reactions are extremely useful for the contemporary organic chemistry researcher in industry or academic institutions. This book provides the information in an easily accessible form. In addition to seminal references and reviews, one or more examples for each name reaction are provided and a complete typical experimental procedure is included, to enable the student or researcher to immediately evaluate reaction conditions. Besides an alphabetical listing of reactions and reagents, cross references permit the organic practitioner to find those name reactions or reagents that enable specific transformations, such as, conversion of amines to nitriles, stereoselective reduction, fluoroalkylation, phenol alkynylation, asymmetric syntheses, allylic alkylation, nucleoside synthesis, cyclopentanation, hydrozirconation, to name a few. Emphasis has been placed on stereoselective and regioselective transformations as well as on enantioselective processes. The listing of reactions and reagents is supported by four indexes.

Author : F. Serratosa
Publisher : Elsevier
Page : 418 pages
File Size : 50,9 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483290928

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Organic Chemistry in Action by F. Serratosa Pdf

Contrary to all other books in the field of organic synthesis, this volume combines Corey's methodology, which is based on the concept of synthon and retrosynthetic analysis, with Evans' methodology based on the `Lapworth model' of alternating polarities. Using this approach, the formation of carbon-carbon bonds and the manipulation of functional groups are treated together, whereas the stereochemical aspects are considered separately. Emphasis is laid on the importance of rigid structures, whether in the starting materials, the synthetic intermediates or the transition states, as a means of controlling the stereochemistry of the organic compounds. Enclosed with the book is a copy of a miniprogram (CHAOS) for an IBM PC, or fully compatible computers, which is an interactive program, affording the beginner a fast and easy way of learning, exploring and looking for new synthetic schemes of molecules of moderate complexity. As a textbook on organic synthesis, this volume will be of immense value at university level.

Author : George S. Zweifel,Michael H. Nantz,Peter Somfai
Publisher : John Wiley & Sons
Page : 422 pages
File Size : 53,9 Mb
Release : 2017-03-27
Category : Science
ISBN : 9781119086536

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Modern Organic Synthesis by George S. Zweifel,Michael H. Nantz,Peter Somfai Pdf

This book bridges the gap between sophomore and advanced / graduate level organic chemistry courses, providing students with a necessary background to begin research in either an industry or academic environment. • Covers key concepts that include retrosynthesis, conformational analysis, and functional group transformations as well as presents the latest developments in organometallic chemistry and C–C bond formation • Uses a concise and easy-to-read style, with many illustrated examples • Updates material, examples, and references from the first edition • Adds coverage of organocatalysts and organometallic reagents

Author : André B. Charette
Publisher : John Wiley & Sons
Page : 706 pages
File Size : 54,8 Mb
Release : 2017-06-26
Category : Science
ISBN : 9781119952299

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Handbook of Reagents for Organic Synthesis by André B. Charette Pdf

The Handbook is a compilation of 99 articles on diverse reagents and catalysts that describe the synthesis of heteroarenes, the building blocks of a wide range of chemicals used in pharma and chemical industries. Articles are selected from the e-EROS database and edited to make sure that it includes only the material relevant to the topic of the book and focus on the synthetic aspects. This makes the articles very focused on the needs of readers wanting information on specific syntheses of specific heteroarenes. In addition, the chemistry of each parent heteroarene is also included to ensure that the reader rapidly finds important information. The Handbook is a part of the Handbook of Reagents for Organic Chemistry series, aiming at collecting articles on a particular theme that individual researchers in academia or industry can use on a daily basis.

Author : W A Smit,A F Bochkov,R Caple
Publisher : Royal Society of Chemistry
Page : 500 pages
File Size : 52,5 Mb
Release : 2007-10-31
Category : Science
ISBN : 9781847551573

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Organic Synthesis by W A Smit,A F Bochkov,R Caple Pdf

The view of organic synthesis as "a concentrated expression of predictive ability and creative capacity" was advocated in the early 1950s. A concise and readable account of the role of synthesis in modern science, Organic Synthesis: The Science Behind the Art presents the general ideology of pursuits in the area of organic synthesis, and examines the methodologies that have evolved in the search for solutions to synthetic problems. This unique book details outstanding achievements of modern organic synthesis, not only for their scientific merits, but also for the aesthetic appeal of the target molecules chosen and the intrinsic beauty of the solutions to the problems posed. By judicious selection of data covering the main areas of synthetic explorations, this book serves to illustrate both the evolution of well-known approaches as well as recently emerged trends most likely to determine the future development of organic synthesis. Special attention is given to the consideration of principles of molecular design in promising and challenging areas of current research. Primarily aimed at advanced undergraduate and graduate students, Organic Synthesis: The Science Behind the Art will also be of interest to teachers, researchers and anyone requiring an introduction to the problems of organic synthesis.

Author : Organic Syntheses, Inc.
Publisher : Wiley-Interscience
Page : 0 pages
File Size : 55,9 Mb
Release : 1998-12-28
Category : Science
ISBN : 0471348872

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Organic Syntheses Collective 11-Volume Set, Volumes 1-74: Indicies; Volumes 1-8: Reaction Guide by Organic Syntheses, Inc. Pdf

Reflecting the increased pace of research and the many recent advances in organic chemistry, this series serves as a single-source compendium of the most up-to-date and significant procedures currently in use.

Author : Anthony W. Czarnik
Publisher : Wiley-Interscience
Page : 176 pages
File Size : 45,9 Mb
Release : 2004-04-07
Category : Science
ISBN : 9780471458487

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Solid-Phase Organic Syntheses by Anthony W. Czarnik Pdf

The rapid expansion of combinatorial chemistry has renewed interest in solid-phase organic synthesis, a method that lends itself well to creating and screening large numbers of lead compounds. Solid-Phase Organic Syntheses, Volume 1 is the first volume in a series that will be updated annually, filling a gap in the existing chemical literature. Providing information previously unavailable from a single resource, this series is dedicated to providing researchers in the field with validated and tested methods for the solid-phase synthesis of interesting and biologically relevant molecules. Solid-phase methods will virtually always be invented for application in combinatorial organic synthesis. To meet these specific needs, Solid-Phase Organic Syntheses, Volume 1 focuses on a single type of synthetic transformation accomplished on solid support, and indicates how procedures are optimized to work with a structurally-wide variety of reagents. Written by recognized leaders in the field who review and test all chemical protocols before publication, organic transformations are organized by type of compound synthesized and reaction type. For the first time, experimental details for proven solid-phase synthetic molecules are collected in a single, invaluable resource. Solid-Phase Organic Syntheses, Volume 1 provides combinatorial chemists and researchers in organic chemistry and medicinal chemistry with the tools and descriptive protocols to achieve syntheses of desired compounds using a variety of solid supports and reagents.

Author : John Andraos
Publisher : CRC Press
Page : 1221 pages
File Size : 47,6 Mb
Release : 2016-04-19
Category : Science
ISBN : 9781420093292

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The Algebra of Organic Synthesis by John Andraos Pdf

The Algebra of Organic Synthesis combines the aims, philosophies, and efforts involved in organic synthesis, reaction optimization, and green chemistry with techniques for determining quantitatively just how "green" synthesis plans are. It provides the first complete quantitative description of synthesis strategy analysis in the context of green ch

Author : Paul Wyatt,Stuart Warren
Publisher : John Wiley & Sons
Page : 55 pages
File Size : 44,8 Mb
Release : 2013-05-20
Category : Science
ISBN : 9781118681442

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Organic Synthesis by Paul Wyatt,Stuart Warren Pdf

Organic Synthesis: Strategy and Control is the long-awaited sequel to Stuart Warren's bestseller Organic Synthesis: The Disconnection Approach, which looked at the planning behind the synthesis of compounds. This unique book now provides a comprehensive, practical account of the key concepts involved in synthesising compounds and focuses on putting the planning into practice. The two themes of the book are strategy and control: solving problems either by finding an alternative strategy or by controlling any established strategy to make it work. The book is divided into five sections that deal with selectivity, carbon-carbon single bonds, carbon-carbon double bonds, stereochemistry and functional group strategy. * A comprehensive, practical account of the key concepts involved in synthesising compounds * Takes a mechanistic approach, which explains reactions and gives guidelines on how reactions might behave in different situations * Focuses on reactions that really work rather than those with limited application * Contains extensive, up-to-date references in each chapter Students and professional chemists familiar with Organic Synthesis: The Disconnection Approach will enjoy the leap into a book designed for chemists at the coalface of organic synthesis.

Author : Michael Smith
Publisher : Academic Press
Page : 1536 pages
File Size : 51,7 Mb
Release : 2011-07-12
Category : Science
ISBN : 9781890661403

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Organic Synthesis by Michael Smith Pdf

The first two chapters provide an introduction to functional groups; these are followed by chapters reviewing basic organic transformations (e.g. oxidation, reduction). The book then looks at carbon-carbon bond formation reactions and ways to 'disconnect' a bigger molecule into simpler building blocks. Most chapters include an extensive list of questions to test the reader's understanding. There is also a new chapter outlining full retrosynthetic analyses of complex molecules which highlights common problems made by scientists.

Author : André B. Charette
Publisher : John Wiley & Sons
Page : 728 pages
File Size : 51,8 Mb
Release : 2017-05-31
Category : Science
ISBN : 9781118704899

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Handbook of Reagents for Organic Synthesis by André B. Charette Pdf

The Handbook is a compilation of 99 articles on diverse reagents and catalysts that describe the synthesis of heteroarenes, the building blocks of a wide range of chemicals used in pharma and chemical industries. Articles are selected from the e-EROS database and edited to make sure that it includes only the material relevant to the topic of the book and focus on the synthetic aspects. This makes the articles very focused on the needs of readers wanting information on specific syntheses of specific heteroarenes. In addition, the chemistry of each parent heteroarene is also included to ensure that the reader rapidly finds important information. The Handbook is a part of the Handbook of Reagents for Organic Chemistry series, aiming at collecting articles on a particular theme that individual researchers in academia or industry can use on a daily basis.