Sex Gender And Epigenetics

Author : Marianne Legato J,Dov Feldberg,Marek Glezerman
Publisher : Elsevier
Page : 316 pages
File Size : 49,7 Mb
Release : 2023-05-23
Category : Medical
ISBN : 9780128239384

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Sex, Gender, and Epigenetics by Marianne Legato J,Dov Feldberg,Marek Glezerman Pdf

Sex, Gender, and Epigenetics: From Molecule to Bedside explores our expanding knowledge of the science of epigenetics in which gene expression is modified as a consequence of small chemical additions to various components of the genome. The book provides an overview of the field, describing the epigenetic phenomena that unite biological sex and environmental experience to create the unique phenome of each individual. The book also analyzes the impact of ancestors’ environmental experience on subsequent generations through the sex-specific transmission of environmentally induced epigenetic modifications. Here, international leaders in the field discuss both sex-specific normal physiology and the experience of disease, with chapters dedicated to fetal programming, the microbiome, cancer, bipolar disorder and schizophrenia, embryogenesis, and oocyte aging, among other topics. Examines the impact of biological sex and gender on gene expression through epigenetic mechanisms, and its relationship to human biology and disease Presents the current state of our understanding of how environmental experience is translated to future generations in a sex specific manner Features chapter contributions from international leaders in the field

Author : Vincenzo E. A. Russo,Robert A. Martienssen,Arthur D. Riggs
Publisher : Unknown
Page : 716 pages
File Size : 41,5 Mb
Release : 1996
Category : Medical
ISBN : UOM:39015047449171

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Epigenetic Mechanisms of Gene Regulation by Vincenzo E. A. Russo,Robert A. Martienssen,Arthur D. Riggs Pdf

Many inheritable changes in gene function are not explained by changes in the DNA sequence. Such epigenetic mechanisms are known to influence gene function in most complex organisms and include effects such as transposon function, chromosome imprinting, yeast mating type switching and telomeric silencing. In recent years, epigenetic effects have become a major focus of research activity. This monograph, edited by three well-known biologists from different specialties, is the first to review and synthesize what is known about these effects across all species, particularly from a molecular perspective, and will be of interest to everyone in the fields of molecular biology and genetics.

Author : Sarah S. Richardson
Publisher : University of Chicago Press
Page : 319 pages
File Size : 40,9 Mb
Release : 2021-11-05
Category : Medical
ISBN : 9780226544809

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The Maternal Imprint by Sarah S. Richardson Pdf

Introduction: The Maternal Imprint -- Sex Equality in Heredity -- Prenatal Culture -- Germ Plasm Hygiene -- Maternal Effects -- Race, Birth Weight, and the Biosocial Body -- Fetal Programming -- It's the Mother! -- Epilogue: Gender and Heredity in the Postgenomic Moment.

Author : Hanping Wang,Francesc Piferrer,Songlin Chen,Zhi-Gang Shen
Publisher : John Wiley & Sons
Page : 1810 pages
File Size : 51,5 Mb
Release : 2018-11-08
Category : Technology & Engineering
ISBN : 9781119127277

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Sex Control in Aquaculture by Hanping Wang,Francesc Piferrer,Songlin Chen,Zhi-Gang Shen Pdf

Awarded Bookauthority's "Best Aquaculture Books of all Time" A comprehensive resource that covers all the aspects of sex control in aquaculture written by internationally-acclaimed scientists Comprehensive in scope, Sex Control in Aquaculture first explains the concepts and rationale for sex control in aquaculture, which serves different purposes. The most important are: to produce monosex stocks to rear only the fastest-growing sex in some species, to prevent precocious or uncontrolled reproduction in other species and to aid in broodstock management. The application of sex ratio manipulation for population control and invasive species management is also included. Next, this book provides detailed and updated information on the underlying genetic, epigenetic, endocrine and environmental mechanisms responsible for the establishment of the sexes, and explains chromosome set manipulation techniques, hybridization and the latest gene knockout approaches. Furthermore, the book offers detailed protocols and key summarizing information on how sex control is practiced worldwide in 35 major aquaculture species or groups, including fish and crustaceans, and puts the focus on its application in the aquaculture industry. With contributions from an international panel of leading scientists, Sex Control in Aquaculture will appeal to a large audience: aquaculture/fisheries professionals and students, scientists or biologists working with basic aspects of fish/shrimp biology, growth and reproductive endocrinology, genetics, molecular biology, evolutionary biology, and R&D managers and administrators. This text explores sex control technologies and monosex production of commercially-farmed fish and crustacean species that are highly in demand for aquaculture, to improve feed utilization efficiency, reduce energy consumption for reproduction and eliminate a series of problems caused by mixed sex rearing. Thus, this book: Contains contributions from an international panel of leading scientists and professionals in the field Provides comprehensive coverage of both established and new technologies to control sex ratios that are becoming more necessary to increase productivity in aquaculture Includes detailed coverage of the most effective sex control techniques used in the world's most important commercially-farmed species Sex Control in Aquaculture is the comprehensive resource for understanding the biological rationale, scientific principles and real-world practices in this exciting and expanding field.

Author : Anonim
Publisher : Elsevier
Page : 478 pages
File Size : 42,6 Mb
Release : 2020-09-30
Category : Medical
ISBN : 9780444641243

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Sex Differences in Neurology and Psychiatry by Anonim Pdf

Sex Differences in Neurology and Psychiatry, Volume 175, addresses this important issue by viewing major neurological and psychiatric conditions through the lens of sexual dimorphism, providing an entirely novel approach to understanding vulnerability factors, as well as potential new treatment strategies in several common neuropsychiatric disorders. The handbook comprises four major sections: (1) Introduction to sex differences in neuroanatomy and neurophysiology, (2) Description of the impact of genetic, epigenetic, sex hormonal and other environmental effects on cerebral sex dimorphism, (3) Review of sex differences in neurologic disorders, and (4) Review of sex differences in psychiatric disorders. Explores sex differences in human neuroanatomy and neurophysiology Offers a pathway toward a gender-specific treatment of neurologic and psychiatric disorders Provides an overview of the genetics of sex hormones, human brain structure, and function, as well as the epigenetics, environment and social context

Author : Nicole Valenzuela,Valentine A. Lance
Publisher : Smithsonian Institution Scholarly Press
Page : 204 pages
File Size : 55,5 Mb
Release : 2004
Category : Science
ISBN : UCSD:31822034180331

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Temperature-Dependent Sex Determination in Vertebrates by Nicole Valenzuela,Valentine A. Lance Pdf

Edited by the world's foremost authorities on the subject, with essays by leading scholars in the field, this work shows how the sex of reptiles and many fish is determined not by the chromosomes they inherit but by the temperature at which incubation takes place.

Author : Peter L. M. Kerkhof,Virginia M. Miller
Publisher : Springer
Page : 725 pages
File Size : 48,6 Mb
Release : 2018-07-26
Category : Medical
ISBN : 9783319779324

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Sex-Specific Analysis of Cardiovascular Function by Peter L. M. Kerkhof,Virginia M. Miller Pdf

This book gathers together contributions from internationally renowned authors in the field of cardiovascular systems and provides crucial insight into the importance of sex- and gender-concepts during the analysis of patient data. This innovative title is the first to offer the elements necessary to consider sex-related properties in both clinical and basic studies regarding the heart and circulation on multiscale levels (i.e. molecular, cellular, electrophysiologically, neuroendocrine, immunoregulatory, organ, allometric, and modeling). Observed differences at (ultra)cellular and organ level are quantified, with focus on clinical relevance and implications for diagnosis and patient management. Since the cardiovascular system is of vital importance for all tissues, Sex-Specific Analysis of Cardiovascular Function is an essential source of information for clinicians, biologists, and biomedical investigators. The wide spectrum of differences described in this book will also act as an eye-opener and serve as a handbook for students, teachers, scientists and practitioners.

Author : Vera Regitz-Zagrosek
Publisher : Springer Science & Business Media
Page : 599 pages
File Size : 44,5 Mb
Release : 2012-10-02
Category : Medical
ISBN : 9783642307263

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Sex and Gender Differences in Pharmacology by Vera Regitz-Zagrosek Pdf

This is the very first book to deal with sex and gender differences in drug therapy - an increasingly recognized medical need. It starts with an overview on S/G in clinical syndromes and a documentation of the medical and socioeconomic damage caused by gender specific adverse drug effects. Part I covers S/G differences in pharmacokinetics. Researchers will be satisfied by the detailed discussion of the mechanisms of S/G differences in drug effects that represents cutting edge science and includes interaction of drugs with sex hormones, genomic and epigenetic mechanisms. It also covers S/G in drug development, in animal models and clinical development and S/G in drug prescriptions. Part II targets S/G differences in drug effects in cardiovascular, pulmonary, CNS, neuromuscular, neuropsychiatric and metabolic diseases, in cancer, inflammation, and rheumatic diseases, in bacterial and retroviral infections, thrombosis, embolism. New drugs will be discussed.

Author : Trygve O. Tollefsbol
Publisher : Academic Press
Page : 618 pages
File Size : 48,9 Mb
Release : 2012-07-26
Category : Medical
ISBN : 9780123884152

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Epigenetics in Human Disease by Trygve O. Tollefsbol Pdf

Epigenetics is one of the fastest growing fields of sciences, illuminating studies of human diseases by looking beyond genetic make-up and acknowledging that outside factors play a role in gene expression. The goal of this volume is to highlight those diseases or conditions for which we have advanced knowledge of epigenetic factors such as cancer, autoimmune disorders and aging as well as those that are yielding exciting breakthroughs in epigenetics such as diabetes, neurobiological disorders and cardiovascular disease. Where applicable, attempts are made to not only detail the role of epigenetics in the etiology, progression, diagnosis and prognosis of these diseases, but also novel epigenetic approaches to the treatment of these diseases. Chapters are also presented on human imprinting disorders, respiratory diseases, infectious diseases and gynecological and reproductive diseases. Since epigenetics plays a major role in the aging process, advances in the epigenetics of aging are highly relevant to many age-related human diseases. Therefore, this volume closes with chapters on aging epigenetics and breakthroughs that have been made to delay the aging process through epigenetic approaches. With its translational focus, this book will serve as valuable reference for both basic scientists and clinicians alike. Comprehensive coverage of fundamental and emergent science and clinical usage Side-by-side coverage of the basis of epigenetic diseases and their treatments Evaluation of recent epigenetic clinical breakthroughs

Author : Cathy Park Hong
Publisher : One World
Page : 224 pages
File Size : 51,9 Mb
Release : 2020-02-25
Category : Biography & Autobiography
ISBN : 9781984820372

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Minor Feelings by Cathy Park Hong Pdf

NEW YORK TIMES BESTSELLER • PULITZER PRIZE FINALIST • NATIONAL BOOK CRITICS CIRCLE AWARD WINNER • ONE OF TIME’S 100 MOST INFLUENTIAL PEOPLE • A ruthlessly honest, emotionally charged, and utterly original exploration of Asian American consciousness “Brilliant . . . To read this book is to become more human.”—Claudia Rankine, author of Citizen In development as a television series starring and adapted by Greta Lee • One of Time’s 10 Best Nonfiction Books of the Year • Named One of the Best Books of the Year by The New York Times, The Washington Post, NPR, New Statesman, BuzzFeed, Esquire, The New York Public Library, and Book Riot Poet and essayist Cathy Park Hong fearlessly and provocatively blends memoir, cultural criticism, and history to expose fresh truths about racialized consciousness in America. Part memoir and part cultural criticism, this collection is vulnerable, humorous, and provocative—and its relentless and riveting pursuit of vital questions around family and friendship, art and politics, identity and individuality, will change the way you think about our world. Binding these essays together is Hong’s theory of “minor feelings.” As the daughter of Korean immigrants, Cathy Park Hong grew up steeped in shame, suspicion, and melancholy. She would later understand that these “minor feelings” occur when American optimism contradicts your own reality—when you believe the lies you’re told about your own racial identity. Minor feelings are not small, they’re dissonant—and in their tension Hong finds the key to the questions that haunt her. With sly humor and a poet’s searching mind, Hong uses her own story as a portal into a deeper examination of racial consciousness in America today. This intimate and devastating book traces her relationship to the English language, to shame and depression, to poetry and female friendship. A radically honest work of art, Minor Feelings forms a portrait of one Asian American psyche—and of a writer’s search to both uncover and speak the truth. Praise for Minor Feelings “Hong begins her new book of essays with a bang. . . .The essays wander a variegated terrain of memoir, criticism and polemic, oscillating between smooth proclamations of certainty and twitches of self-doubt. . . . Minor Feelings is studded with moments [of] candor and dark humor shot through with glittering self-awareness.”—The New York Times “Hong uses her own experiences as a jumping off point to examine race and emotion in the United States.”—Newsweek “Powerful . . . [Hong] brings together memoiristic personal essay and reflection, historical accounts and modern reporting, and other works of art and writing, in order to amplify a multitude of voices and capture Asian America as a collection of contradictions. She does so with sharp wit and radical transparency.”—Salon

Author : Maurizio Meloni,John Cromby,Des Fitzgerald,Stephanie Lloyd
Publisher : Springer
Page : 941 pages
File Size : 49,8 Mb
Release : 2017-10-27
Category : Social Science
ISBN : 9781137528797

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The Palgrave Handbook of Biology and Society by Maurizio Meloni,John Cromby,Des Fitzgerald,Stephanie Lloyd Pdf

This comprehensive handbook synthesizes the often-fractured relationship between the study of biology and the study of society. Bringing together a compelling array of interdisciplinary contributions, the authors demonstrate how nuanced attention to both the biological and social sciences opens up novel perspectives upon some of the most significant sociological, anthropological, philosophical and biological questions of our era. The six sections cover topics ranging from genomics and epigenetics, to neuroscience and psychology to social epidemiology and medicine. The authors collaboratively present state-of-the-art research and perspectives in some of the most intriguing areas of what can be called biosocial and biocultural approaches, demonstrating how quickly we are moving beyond the acrimonious debates that characterized the border between biology and society for most of the twentieth century. This landmark volume will be an extremely valuable resource for scholars and practitioners in all areas of the social and biological sciences. The chapter 'Ten Theses on the Subject of Biology and Politics: Conceptual, Methodological, and Biopolitical Considerations' is open access under a CC BY 4.0 license via link.springer.com. Versions of the chapters 'The Transcendence of the Social', 'Scrutinizing the Epigenetics Revolution', 'Species of Biocapital, 2008, and Speciating Biocapital, 2017' and 'Experimental Entanglements: Social Science and Neuroscience Beyond Interdisciplinarity' are available open access via third parties. For further information please see license information in the chapters or on link.springer.com.

Author : Hannah Fitsch,Flora Lysen,Suparna Choudhury
Publisher : Frontiers Media SA
Page : 114 pages
File Size : 42,8 Mb
Release : 2022-02-17
Category : Science
ISBN : 9782889742868

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Challenges of Interdisciplinary Research in the Field of Critical (Sex/ Gender) Neuroscience by Hannah Fitsch,Flora Lysen,Suparna Choudhury Pdf

Author : Marianne J. Legato
Publisher : Academic Press
Page : 792 pages
File Size : 43,8 Mb
Release : 2017-05-15
Category : Medical
ISBN : 9780128035429

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Principles of Gender-Specific Medicine by Marianne J. Legato Pdf

The announcement that we had decoded the human genome in 2000 ushered in a new and unique era in biomedical research and clinical medicine. This Third Edition of Principles of Gender-Specific Medicine focuses, as in the past two editions, on the essentials of sexual dimorphism in human physiology and pathophysiology, but emphasizes the latest information about molecular biology and genomic science in a variety of disciplines. Thus, this edition is a departure from the previous two; the editor solicited individual manuscripts from innovative scientists in a variety of fields rather than the traditional arrangement of sections devoted to the various subspecialties of medicine edited by section chiefs. Wherever it was available, these authors incorporated the latest information about the impact of the genome and the elements that modify its expression on human physiology and illness. All chapters progress translationally from basic science to the clinical applications of gender-specific therapy and suggest the most important topics for future investigation. This book is essential reading for all biomedical investigators and medical educators involved in gender-specific medicine. It will also be useful for primary care practitioners who need information about the importance of sex and gender in the prevention, diagnosis and treatment of illness. Outlines sex-specific differences in normal human function and explains the impact of age, hormones, and environment on the incidence and outcome of illness Reflects the latest information about the molecular basis of the sexual dimorphism in human physiology and the experience of disease Reviews the implications of our ever-improving ability to describe the genetic basis of vulnerability to disease and our capacity to alter the genome itself Illustrates the importance of new NIH guidelines that urge the inclusion of sex as a variable in research protocols

Author : Bill Sullivan
Publisher : National Geographic Books
Page : 340 pages
File Size : 55,8 Mb
Release : 2019-08-06
Category : Science
ISBN : 9781426220562

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Pleased to Meet Me by Bill Sullivan Pdf

Why are you attracted to a certain "type?" Why are you a morning person? Why do you vote the way you do? From a witty new voice in popular science comes a clever, life-changing look at what makes you you. "I can't believe I just said that." "What possessed me to do that?" "What's wrong with me?" We're constantly seeking answers to these fundamental human questions, and now, science has the answers. The foods we enjoy, the people we love, the emotions we feel, and the beliefs we hold can all be traced back to our DNA, germs, and environment. This witty, colloquial book is popular science at its best, describing in everyday language how genetics, epigenetics, microbiology, and psychology work together to influence our personality and actions. Mixing cutting-edge research and relatable humor, Pleased to Meet Me is filled with fascinating insights that shine a light on who we really are--and how we might become our best selves.

Author : Marianne Legato J
Publisher : Academic Press
Page : 932 pages
File Size : 45,7 Mb
Release : 2023-04-03
Category : Technology & Engineering
ISBN : 9780323958271

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Principles of Gender-Specific Medicine by Marianne Legato J Pdf

Awarded with the 2018 Prose Award in Clinical Medicine, the third edition of Principles of Gender-Specific Medicine explored and described exciting new areas in biomedicine that integrated technology into the treatment of disease and the augmentation of human function. Novel topics such as the sex-specific aspects of space medicine, the development and the use of genderized robots and a discussion of cyborgs were included in the third edition, providing a preview of the expanding world of sex-specific physiology and therapeutics. This Fourth Edition is a continuation of the mission to trace the relevance of biological sex to normal function and to the experience of disease in humans.We are now twenty years into the postgenomic era. The investigation of how the genome produces the phenome has led to fascinating insights as well as yet unanswered questions. Principles of Gender-Specific Medicine, Fourth Edition, has a central theme: discuss advances in understanding the role of epigenetics in regulating gene expression in a dynamic, sex-specific way during human life. It explores the protean role of epigenetics in human physiology, the relevance of environmental experience to human function, the therapeutic promise of cutting-edge methodologies like gene manipulation, the preparation of humans for space travel, the use of artificial intelligence in detection and therapeutic decisions concerning disease states, the possibilities for technological support of not only compromised individuals but of the augmentation of human function, and an analysis of the benefits, limitations and issues that surround our current expectations of personalized medicine. Covers the most important developments in biomedical research in the past decade, with a thoughtful analysis of how they impact patient care Discusses the feasibility and usefulness of personalized medicine, the limits and promise of genetic editing, the basis for variation in sexual identity and how artificial intelligence and technology will affect basic human function as well as correcting disability Promotes and facilitates discussions about the ethics and governance issues that surround much of what science is now able to do at the most basic levels of human’s physiology