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Skeletal Aging and Osteoporosis by Matthew J. Silva Pdf
The focus of this book is on mechanical aspects of skeletal fragility related to aging and osteoporosis. Topics include: Age-related changes in trabecular structure and strength; age-related changes in cortical material properties; age-related changes in whole-bone structure; predicting bone strength and fracture risk using image-based methods and finite element analysis; animal models of osteoporosis and aging; age-related changes in skeletal mechano responsiveness; exercise and physical interventions for osteoporosis.
Skeletal Aging and Osteoporosis by Matthew J. Silva Pdf
The focus of this book is on mechanical aspects of skeletal fragility related to aging and osteoporosis. Topics include: Age-related changes in trabecular structure and strength; age-related changes in cortical material properties; age-related changes in whole-bone structure; predicting bone strength and fracture risk using image-based methods and finite element analysis; animal models of osteoporosis and aging; age-related changes in skeletal mechano responsiveness; exercise and physical interventions for osteoporosis.
United States Public Health Service,Surgeon General of the United States
Author : United States Public Health Service,Surgeon General of the United States Publisher : Unknown Page : 0 pages File Size : 43,5 Mb Release : 2004-12 Category : Health & Fitness ISBN : 1410219275
Bone Health and Osteoporosis by United States Public Health Service,Surgeon General of the United States Pdf
This first-ever Surgeon General's Report on bone health and osteoporosis illustrates the large burden that bone disease places on our Nation and its citizens. Like other chronic diseases that disproportionately affect the elderly, the prevalence of bone disease and fractures is projected to increase markedly as the population ages. If these predictions come true, bone disease and fractures will have a tremendous negative impact on the future well-being of Americans. But as this report makes clear, they need not come true: by working together we can change the picture of aging in America. Osteoporosis, fractures, and other chronic diseases no longer should be thought of as an inevitable part of growing old. By focusing on prevention and lifestyle changes, including physical activity and nutrition, as well as early diagnosis and appropriate treatment, Americans can avoid much of the damaging impact of bone disease and other chronic diseases. This Surgeon General's Report brings together for the first time the scientific evidence related to the prevention, assessment, diagnosis, and treatment of bone disease. More importantly, it provides a framework for moving forward. The report will be another effective tool in educating Americans about how they can promote bone health throughout their lives. This first-ever Surgeon General's Report on bone health and osteoporosis provides much needed information on bone health, an often overlooked aspect of physical health. This report follows in the tradition of previous Surgeon Generals' reports by identifying the relevant scientific data, rigorously evaluating and summarizing the evidence, and determining conclusions.
The Aging Skeleton by Clifford J. Rosen,Julie Glowacki,John P. Bilezikian Pdf
The Aging Skeleton provides students and clinicians with a comprehensive review of all aspects of the human skeleton as it ages. It offers information on basic mechanisms and pathways as well as pathobiology.
Osteoporosis in Men by Eric S. Orwoll,John P. Bilezikian,Dirk Vanderschueren Pdf
Since the publication of the first edition, the U.S. Surgeon General released the first-ever report on bone health and osteoporosis in October 2004. This report focuses even more attention on the devastating impact osteoporosis has on millions of lives. According to the National Osteoporosis Foundation, 2 million American men have osteoporosis, and another 12 million are at risk for this disease. Yet despite the large number of men affected, the lack of awareness by doctors and their patients puts men at a higher risk that the condition may go undiagnosed and untreated. It is estimated that one-fifth to one-third of all hip fractures occur in men. This second edition brings on board John Bilezikian and Dirk Vanderschueren as editors with Eric Orwoll. The table of contents is more than doubling with 58 planned chapters. The format is larger – 8.5 x 11. This edition of Osteoporosis in Men brings together even more eminent investigators and clinicians to interpret developments in this growing field, and describe state-of-the-art research as well as practical approaches to diagnosis, prevention and therapy. Brings together more eminent investigators and clinicians to interpret developments in this growing field Describes state-of-the-art research as well as practical approaches to diagnosis, prevention and therapy There is no book on the market that covers osteoporosis in men as comprehensively as this book
Human Cell Transformation by Johng S. Rhim,Anatoly Dritschilo,Richard Kremer Pdf
This book, part contributed volume, part proceedings, discusses state-of-the-art advances on human cell transformation in cell models for the study of cancer and aging. Several of the chapters are from the Human Cell Transformation: Advances in Cell Models for the Study of Cancer and Aging conference that was held in June 2018 at McGill University. The authors represent international expertise on a wide variety of topics ranging from different types of cancer (prostate, bone, breast, etc.) to tumor microenvironment, tumor progression, homogeneity, and possible therapies and treatments.
Fragility Fracture Nursing by Karen Hertz,Julie Santy-Tomlinson Pdf
This open access book aims to provide a comprehensive but practical overview of the knowledge required for the assessment and management of the older adult with or at risk of fragility fracture. It considers this from the perspectives of all of the settings in which this group of patients receive nursing care. Globally, a fragility fracture is estimated to occur every 3 seconds. This amounts to 25 000 fractures per day or 9 million per year. The financial costs are reported to be: 32 billion EUR per year in Europe and 20 billon USD in the United States. As the population of China ages, the cost of hip fracture care there is likely to reach 1.25 billion USD by 2020 and 265 billion by 2050 (International Osteoporosis Foundation 2016). Consequently, the need for nursing for patients with fragility fracture across the world is immense. Fragility fracture is one of the foremost challenges for health care providers, and the impact of each one of those expected 9 million hip fractures is significant pain, disability, reduced quality of life, loss of independence and decreased life expectancy. There is a need for coordinated, multi-disciplinary models of care for secondary fracture prevention based on the increasing evidence that such models make a difference. There is also a need to promote and facilitate high quality, evidence-based effective care to those who suffer a fragility fracture with a focus on the best outcomes for recovery, rehabilitation and secondary prevention of further fracture. The care community has to understand better the experience of fragility fracture from the perspective of the patient so that direct improvements in care can be based on the perspectives of the users. This book supports these needs by providing a comprehensive approach to nursing practice in fragility fracture care.
Osteoporosis in Older Persons by Gustavo Duque,Douglas P. Kiel Pdf
The book summarizes recent advances in the elucidation of the mechanisms involved in senile osteoporosis as well as its potential treatment, bringing an integrated approach from the bench to the clinical practice. A unique aspect of this book is its emphasis on the application of translational research in the field of osteoporosis and falls. The book provides a complete review on the prevention as well as current and future treatments of osteoporosis.
Dr. Lani's No-Nonsense Bone Health Guide by Lani Simpson Pdf
Part whistle-blower book, part bone health bible, Dr. Lani's No-Nonsense Bone Health Guide exposes the shocking difficulty involved in getting an accurate bone density reading and the serious risks of long term use of the most recent osteoporosis medications. Author Dr. Lani Simpson, both a Doctor of Chiropractic and a Certified Clinical Densitometrist cuts through the confusion and inaccuracies surrounding osteoporosis to explain her whole-body approach to bone health, which includes discussions of digestive health, diet, supplements, and exercise. You may be surprised to learn which foods and medicines hurt bone health and which ones help in building strong bones. The book also sheds light on basic bone biology, how aging affects the bones, the risks and benefits of drugs and alternative treatments, a comprehensive breakdown of calcium supplementation – and some delicious recipes for bone-building meals. We all share concerns about bone health and osteoporosis. Whether you are one of the nearly 10,000 baby boomers turning 65 every day, or a younger person building a healthy body, Dr. Lani’s No-Nonsense Bone Health Guide will answer your questions and help you live long, healthy, and fracture-free into your golden years.
Osteoporosis in Older Persons by Gustavo Duque,Douglas P. Kiel Pdf
This new edition includes the most up-to-date information about the pathophysiology and new therapeutic alternatives for osteoporosis of advanced age. It is written by investigators (clinicians and basic scientists) in the field of aging bone research. It was just recently that a new syndrome, osteoporosis of advanced age, was recognized as a new entity with its own pathophysiology and potential treatments. Unfortunately, and despite the fact that hip fractures are mostly a consequence of this process, and apart from the first edition of this book, there are few publications about this subject. The first edition of this book demonstrated that there is a need to understand the particular features of osteoporosis in older persons, which is the main aim of this book. The institutions where the authors are affiliated are highly recognized as the main centers in aging bone research. As an innovation, the second edition includes some aspects of muscle and bone interaction focusing of the impact of age-related muscle loss (sarcopenia) on the pathogenesis of falls and fractures in older persons. As in the previous edition, this book is expected to be the reference guide for geriatricians, gerontologists, and bone biologists as well as medical trainees in order to understand the mechanisms of senile osteoporosis with a practical approach to the treatment of its consequences.
Biochemistry and Cell Biology of Ageing: Part II Clinical Science by J. Robin Harris,Viktor I. Korolchuk Pdf
This volume of the subcellular Biochemistry series will attempt to bridge the gap between the subcellular events that are related to aging as they were described in the first volume of this set of two books and the reality of aging as this is seen in clinical practice. All chapters will start from the biochemistry or cell biology, where the data is available and work up towards the understanding that we have of aging in the various areas that are related to the subject. Key focus points for this volume are nutrition, external factors and genetics on aging. There will also be chapters that will focus on various organs or tissues in which aging has been well studied, like the eyes, the muscles, the immune system and the bones. The aim of the book project and the book project that is published in concert with this volume is to bring the subcellular and clinical areas into closer contact.
Bone Loss and Osteoporosis by Sabrina C. Agarwal,Samuel D. Stout Pdf
With the growing incidence of fragility fractures in Europe and North America over the last three decades, bone loss and osteoporosis have become active areas of research in skeletal biology. Bone loss is associated with aging in both sexes and is accelerated in women with the onset of menopause. However, bone loss is related to a suite of complex and often synergistically related factors including genetics, pathology, nutrition, mechani cal usage, and lifestyle. It is not surprising that its incidence and severity vary among populations. There has been increasing interest to investigate bone loss and osteoporosis from an anthropological perspective that utilizes a biocultural approach. Biocultural approaches recognize the inter-relationship between biological, cultural, and environmental variables. Anthropological studies also highlight the value of evolutionary and population approaches to the study of bone loss. These approaches are particularly suited to elucidate the multifactorial etiology of bone loss. The idea for this volume came out of a symposium organized by the editors at the 70th annual meeting of The American Association of Physical Anthropologists in Kansas City, Missouri. Many of the symposium participants, along with several additional leading scientists involved in bone and osteoporosis research, are brought together in this volume. Each chapter focuses on a different aspect of bone loss and fragility with a fresh and stimulating perspective.
How osteoporosis went from a normal aging process to a disease. In the middle of the twentieth century, few physicians could have predicted that the modern diagnostic category of osteoporosis would emerge to include millions of Americans, predominantly older women. Before World War II, popular attitudes held that the declining physical and mental health of older persons was neither preventable nor reversible and that older people had little to contribute. Moreover, the physiological processes that influenced the health of bones remained mysterious. In Aging Bones, Gerald N. Grob makes a historical inquiry into how this one aspect of aging came to be considered a disease. During the 1950s and 1960s, as more and more people lived to the age of 65, older people emerged as a self-conscious group with distinct interests, and they rejected the pejorative concept of senescence. But they had pressing health needs, and preventing age-related decline became a focus for researchers and clinicians alike. In analyzing how the normal aging of bones was transformed into a medical diagnosis requiring treatment, historian of medicine Grob explores developments in medical science as well as the social, intellectual, economic, demographic, and political changes that transformed American society in the post–World War II decades. Though seemingly straightforward, osteoporosis and its treatment are shaped by illusions about the conquest of disease and aging. These illusions, in turn, are instrumental in shaping our health care system. While bone density tests and osteoporosis treatments are now routinely prescribed, aggressive pharmaceutical intervention has produced results that are inconclusive at best. The fascinating history in Aging Bones will appeal to students and scholars in the history of medicine, health policy, gerontology, endocrinology, and orthopedics, as well as anyone who has been diagnosed with osteoporosis.
Osteoporotic Fracture and Systemic Skeletal Disorders by Hideaki E. Takahashi,David B. Burr,Noriaki Yamamoto Pdf
This edited book describes what fragile bone is, how the condition is assessed, and how it can be treated. It is intended for multi-professional trainees and practitioners in health and social care fields who care for and treat the elderly. Chapters within the book provide the latest advances in cell and molecular biology, morphology, radiology, and the biomechanics of bone in health and disease. The basic concept of “Remodeling” and “Modeling” is described for better understanding of the mechanisms of osteoporosis. Methods of identifying and assessing osteoporosis are described, as are risk factors for bone fracture and non-unions. Furthermore, the effects of various drugs used to treat osteoporosis at both material and structural levels of bone and their cost effectiveness are described. Operative treatments for fracture that maintain or improve the quality of life of patients are included Treatment of Osteoporotic Fracture and Systemic Skeletal Disorders attempts to provide a holistic and translational view of the pathogenesis and treatment of osteoporosis and some other musculoskeletal diseases, with an overview of treatment modalities in various clinical settings.