Skin Cancer Basic Science Clinical Research And Treatment

Author : Claus Garbe,Stefan Schmitz,Constantin E. Orfanos
Publisher : Springer
Page : 440 pages
File Size : 46,5 Mb
Release : 2012-01-06
Category : Medical
ISBN : 364278772X

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Skin Cancer: Basic Science, Clinical Research and Treatment by Claus Garbe,Stefan Schmitz,Constantin E. Orfanos Pdf

In the past two decades, considerable interest in skin cancer has developed in the public and scientific communities. There may have been several reasons for this: - The rise in the global incidence of cutaneous cancers - New molecular biology techniques resulting in a better understanding of pathogenesis and improved diagnostic procedures - The advent of new pathological entities, e. g. , the endemic form of Kaposi's sarcoma - A constantly increasing range of therapeutic modalities, providing even more efficacious treatment and manage ment of skin cancers As N. E. Fusenig describes in the first chapter of this volume, basic research is only beginning to unravel the complex mechanism involved in cellular dedifferentiation and tumor progression. Progress is dearly needed, especially in dermato oncology, where the rise in the incidence of epithelial tumors has inflated the overall skin cancer incidence. The incidence of tumors of the skin exceeds that of all other neoplasias in humans, with recreational sun exposure being a suspected primary cause. Several studies on the effects of UV radiation have been included at the beginning of this volume. Even the role of long wavelength UV (UVA) has become a focus of research activities. The main concern is that the low carcinogenicity of UVA, in comparison to UVB, may be outweighed and exceeded in its effects by increased UV A exposure, e. g.

Author : Claus Garbe,Stefan Schmitz,Constantin E. Orfanos
Publisher : Springer Verlag
Page : 440 pages
File Size : 54,8 Mb
Release : 1995-01-01
Category : Medical
ISBN : 0387576304

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Skin Cancer by Claus Garbe,Stefan Schmitz,Constantin E. Orfanos Pdf

Author : Howard L. Kaufman,Janice M. Mehnert
Publisher : Springer
Page : 416 pages
File Size : 44,5 Mb
Release : 2015-11-24
Category : Medical
ISBN : 9783319225395

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Melanoma by Howard L. Kaufman,Janice M. Mehnert Pdf

Melanoma is one of the most types of cancer. When melanoma is detected at an early stage, treatment is highly successful, but outcomes can be poor when the disease is advanced. There has been significant progress in our understanding of the molecular biology, genetics, and immunology of melanoma over the past decade. This has been accompanied by rapid advances in therapeutic strategies for patients with melanoma. This book provides the clinician and the researcher with a broad understanding of the molecular and cellular pathogenesis of melanoma, explores the clinical characteristics and criteria for clinical and pathological staging of the disease, and provides an overview of current and evolving treatment strategies in the adjuvant, metastatic, and preventive settings. The treatment of special populations and rare variants of melanoma that often present particular clinical challenges is also covered. Authored by international experts in melanoma biology and clinical management, this volume concisely explains how to diagnose, treat, and prevent melanoma while reviewing advances in basic science and providing an overview of innovative approaches still under development.

Author : Stanley J. Miller,Mary E. Maloney
Publisher : Wiley-Blackwell
Page : 1024 pages
File Size : 51,7 Mb
Release : 1998-02-11
Category : Medical
ISBN : 0865425175

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Cutaneous Oncology by Stanley J. Miller,Mary E. Maloney Pdf

This book was written to fill a perceived void in the current literature. Cutaneous Oncology is designed to focus on the nature and behaviour of cancers, standing at the junction of clinical medicine and basic science research to provide a whole picture of skin tumor biology to both clinicians and researchers. The book explains our clinical understanding of skin cancers in terms of their biological and molecular bases, and provides a framework of clinical settings in which to understand and appreciate the importance of individual facets of tumor biology.

Author : Julia A. Newton Bishop,Martin Gore
Publisher : John Wiley & Sons
Page : 302 pages
File Size : 47,9 Mb
Release : 2008-04-15
Category : Medical
ISBN : 9781405149952

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Melanoma by Julia A. Newton Bishop,Martin Gore Pdf

Melanoma is the most life threatening form of skin cancer, the incidence of which has been rising in the developing world due to its link with sun exposure. The increase in incidence had made it imperative that clinicians managing these patients keep up-to-date with the latest advances, allowing them to provide optimal treatment. As with the other Challenges books, Challenges in Melanoma assumes a certain level of knowledge and builds on this by discussing only areas of controversy and uncertainty in the basic science and clinical management of the disease. Authors aim to provide a balanced answer based on the scientific evidence, but ultimately draw some conclusions that will be of relevance to clinical practice. The content is organised into three sections: aetiology; diagnosis, screening and prevention; and management. All the chapters ask practical and pertinent questions. The book takes a global view of melanoma as a public health risk as well as looking at management issues.

Author : U.s. Department of Health and Human Services,Office of the Surgeon General
Publisher : Createspace Independent Publishing Platform
Page : 112 pages
File Size : 47,7 Mb
Release : 2014-10-21
Category : Medical
ISBN : 1502903857

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The Surgeon General's Call to Action to Prevent Skin Cancer by U.s. Department of Health and Human Services,Office of the Surgeon General Pdf

Skin cancer is the most commonly diagnosed cancer in the United States, yet most cases are preventable. Every year in the United States, nearly 5 million people are treated for skin cancer, at an estimated cost of $8.1 billion. Melanoma, the most deadly form of skin cancer, causes nearly 9,000 deaths each year. Despite recent efforts to address risk factors, skin cancer rates continue to rise. While those with lighter skin are more susceptible, anyone can get skin cancer—and it can be serious, even deadly. Almost all of the conditions can be caused by unnecessary ultraviolet (UV) radiation exposure, usually from excessive time in the sun or from the use of indoor tanning devices. It is alarming that every year, nearly one out of every three young white women aged 16–25 engages in indoor tanning. It's important to shatter the myth that tanned skin is a sign of health. And a “base” tan is not a “safe” tan. Tanned skin is damaged skin. Understanding the risk of UV exposure is crucial to protecting ourselves and our loved ones. That is why “The Surgeon General's Call to Action to Prevent Skin Cancer” is important for all of us. It outlines action steps we can all take—as individuals, parents, educators, employers, policy makers, health care professionals, and communities—to reverse this alarming trend. As a nation, we can all do more to address skin cancer as a serious public health challenge. Everyone is urged to find out more about the risk of skin cancer—and what we all can do to prevent it.

Author : Craig A. Almeida,Sheila A. Barry
Publisher : John Wiley & Sons
Page : 364 pages
File Size : 45,5 Mb
Release : 2011-08-26
Category : Science
ISBN : 9781444357394

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Cancer by Craig A. Almeida,Sheila A. Barry Pdf

“... Useful background information is displayed in blue boxes, and good use is made of numerous tables and diagrams... a useful book for the undergraduate medical or allied health professional...” –Oncology News, May/June 2010 This forward looking cancer biology book appeals to a wide ranging audience. Introductory chapters that provide the molecular, cellular, and genetic information needed to comprehend the material of the subsequent chapters bring unprepared students up to speed for the rest of the book and serve as a useful refresher for those with previous biology background. The second set of chapters focuses on the main cancers in terms of risk factors, diagnostic and treatment methods and relevant current research. The final section encompasses the immune system’s role in the prevention and development of cancer and the impact that the Human Genome Project will have on future approaches to cancer care. While best suited to non-majors cancer biology courses, the depth provided satisfies courses that combine both majors and non-majors. Also, and deliberately, the authors have incorporated relevant information on diagnosis and treatment options that lend appeal to the lay reader.

Author : Anonim
Publisher : Unknown
Page : 128 pages
File Size : 43,7 Mb
Release : 2024-07-01
Category : Electronic
ISBN : OCLC:1125727614

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Cutaneous Melanoma by Anonim Pdf

Author : Claus Garbe,Stefan Schmitz,Constantin E. Orfanos
Publisher : Springer Science & Business Media
Page : 402 pages
File Size : 43,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642787713

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Skin Cancer: Basic Science, Clinical Research and Treatment by Claus Garbe,Stefan Schmitz,Constantin E. Orfanos Pdf

In the past two decades, considerable interest in skin cancer has developed in the public and scientific communities. There may have been several reasons for this: - The rise in the global incidence of cutaneous cancers - New molecular biology techniques resulting in a better understanding of pathogenesis and improved diagnostic procedures - The advent of new pathological entities, e. g. , the endemic form of Kaposi's sarcoma - A constantly increasing range of therapeutic modalities, providing even more efficacious treatment and manage ment of skin cancers As N. E. Fusenig describes in the first chapter of this volume, basic research is only beginning to unravel the complex mechanism involved in cellular dedifferentiation and tumor progression. Progress is dearly needed, especially in dermato oncology, where the rise in the incidence of epithelial tumors has inflated the overall skin cancer incidence. The incidence of tumors of the skin exceeds that of all other neoplasias in humans, with recreational sun exposure being a suspected primary cause. Several studies on the effects of UV radiation have been included at the beginning of this volume. Even the role of long wavelength UV (UVA) has become a focus of research activities. The main concern is that the low carcinogenicity of UVA, in comparison to UVB, may be outweighed and exceeded in its effects by increased UV A exposure, e. g.

Author : Stephen N. Snow,George R. Mikhail
Publisher : Univ of Wisconsin Press
Page : 464 pages
File Size : 49,9 Mb
Release : 2004
Category : Mohs surgery
ISBN : 0299204707

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Mohs Micrographic Surgery by Stephen N. Snow,George R. Mikhail Pdf

Mohs Micrographic Surgery, an advanced treatment procedure for skin cancer, offers the highest potential for recovery--even if the skin cancer has been previously treated. This procedure is a state-of-the-art treatment in which the physician serves as surgeon, pathologist, and reconstructive surgeon. It relies on the accuracy of a microscope to trace and ensure removal of skin cancer down to its roots. This procedure allows dermatologists trained in Mohs Surgery to see beyond the visible disease and to precisely identify and remove the entire tumor, leaving healthy tissue unharmed. This procedure is most often used in treating two of the most common forms of skin cancer: basal cell carcinoma and squamous cell carcinoma. The cure rate for Mohs Micrographic Surgery is the highest of all treatments for skin cancer--up to 99 percent even if other forms of treatment have failed. This procedure, the most exact and precise method of tumor removal, minimizes the chance of regrowth and lessens the potential for scarring or disfigurement

Author : Armand B Cognetta,William M. Mendenhall
Publisher : Springer Science & Business Media
Page : 256 pages
File Size : 43,9 Mb
Release : 2013-06-13
Category : Medical
ISBN : 9781461469865

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Radiation Therapy for Skin Cancer by Armand B Cognetta,William M. Mendenhall Pdf

Photon Radiation Therapy for Skin Malignancies is a vital resource for dermatologists interested in radiation therapy, including the physics and biology behind treatment of skin cancers, as well as useful and pragmatic formulas and algorithms for evaluating and treating them. Dermatology has always been a field that overlaps multiple medical specialties and this book is no exception, with its focus on both dermatologists and radiation oncologists. It is estimated that between 2010 and 2020, the demand for radiation therapy will exceed the number of radiation oncologists practicing in the U.S. tenfold, which could profoundly affect the ability to provide patients with sufficient access to treatment. Photon Radiation Therapy for Skin Malignancies enhances the knowledge of dermatologists and radiation oncologists and presents them with the most up-to-date information regarding detection, delineation and depth determination of skin cancers, and appropriate biopsy techniques. In addition, the book also addresses radiation therapy of the skin and the skin’s reactions to radiation therapy.

Author : Eggert Stockfleth,Ted Rosen,Steven Schumaak
Publisher : Springer Science & Business Media
Page : 232 pages
File Size : 48,5 Mb
Release : 2010-02-26
Category : Medical
ISBN : 9783540793472

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Managing Skin Cancer by Eggert Stockfleth,Ted Rosen,Steven Schumaak Pdf

Skin cancer is the most common malignant neoplasm and its incidence is rising worldwide. The epidemic increase in such tumors calls for efficient management by the application of appropriate guidelines for therapy and prevention. Clinicians managing these patients need to keep up to date with the latest advances, allowing them to provide optimal treatment. This practical guide offers the reader a comprehensive overview of the options for the diagnosis, treatment, and prevention of cutaneous cancer. It covers all common skin cancers and also rarer lesions. Employing an "evidence-based medicine" approach, this truly international work presents a well-illustrated text in a reader-friendly format with step-by-step guidelines and visual flowcharts. Dermatologists, oncologists, and all other interested physicians will find this book an extraordinarily valuable resource for the clinical management of cutaneous cancer in their daily practice.

Author : Thomas P. Habif
Publisher : Unknown
Page : 938 pages
File Size : 55,7 Mb
Release : 1996
Category : Medical
ISBN : UOM:39015034537525

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Clinical Dermatology by Thomas P. Habif Pdf

This accurate, profusely illustrated guide to the diagnosis and treatment of skin abnormalities and diseases covers various topical therapies as well as specific skin diseases such as dermatitis, warts, diseases, and tumors. It also details surgical procedures and chemical peels.

Author : Institute of Medicine,Division of Health Care Services,Committee on Medicare Coverage Extensions
Publisher : National Academies Press
Page : 410 pages
File Size : 49,8 Mb
Release : 2000-05-07
Category : Medical
ISBN : 9780309068895

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Extending Medicare Coverage for Preventive and Other Services by Institute of Medicine,Division of Health Care Services,Committee on Medicare Coverage Extensions Pdf

This report, which was developed by an expert committee of the Institute of Medicine, reviews the first three services listed above. It is intended to assist policymakers by providing syntheses of the best evidence available about the effectiveness of these services and by estimating the cost to Medicare of covering them. For each service or condition examined, the committee commissioned a review of the scientific literature that was presented and discussed at a public workshop. As requested by Congress, this report includes explicit estimates only of costs to Medicare, not costs to beneficiaries, their families, or others. It also does not include cost-effectiveness analyses. That is, the extent of the benefits relative to the costs to Medicareâ€"or to society generallyâ€"is not evaluated for the services examined. The method for estimating Medicare costs follows the generic estimation practices of the Congressional Budget Office (CBO). The objective was to provide Congress with estimates that were based on familiar procedures and could be compared readily with earlier and later CBO estimates. For each condition or service, the estimates are intended to suggest the order of magnitude of the costs to Medicare of extending coverage, but the estimates could be considerably higher or lower than what Medicare might actually spend were coverage policies changed. The estimates cover the five-year period 2000-2004. In addition to the conclusions about specific coverage issues, the report examines some broader concerns about the processes for making coverage decisions and about the research and organizational infrastructure for these decisions. It also briefly examines the limits of coverage as a means of improving health services and outcomes and the limits of evidence as a means of resolving policy and ethical questions.

Author : IARC Working Group on Risk of Skin Cancer and Exposure to Artificial Ultraviolet Light,International Agency for Research on Cancer
Publisher : World Health Organization
Page : 84 pages
File Size : 49,8 Mb
Release : 2006
Category : Medical
ISBN : IND:30000110603366

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Exposure to Artificial UV Radiation and Skin Cancer by IARC Working Group on Risk of Skin Cancer and Exposure to Artificial Ultraviolet Light,International Agency for Research on Cancer Pdf

This report represents the views and expert opinions of an IARC Working Group that met in Lyon, France, 27-29 June 2005