Small Stress Proteins

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Small Stress Proteins

Author : A.-P. Arrigo,W.E.G. Müller
Publisher : Springer Science & Business Media
Page : 277 pages
File Size : 47,5 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642563485

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Small Stress Proteins by A.-P. Arrigo,W.E.G. Müller Pdf

This book gives a comprehensive survey of the current knowledge of the expression and function of small stress proteins (sHsps) in different organisms, from prokaryotes to humans. It provides an overview of the diversity and complex evolutionary history of sHsps and describes their function and expression in different eukaryote models. Additional chapters discuss the role of sHsps in pathological conditions and gene therapy approaches towards a control of sHsp expression levels.

The Big Book on Small Heat Shock Proteins

Author : Robert M. Tanguay,Lawrence E. Hightower
Publisher : Springer
Page : 610 pages
File Size : 43,8 Mb
Release : 2015-06-15
Category : Medical
ISBN : 9783319160771

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The Big Book on Small Heat Shock Proteins by Robert M. Tanguay,Lawrence E. Hightower Pdf

Based upon a workshop entitled “The Small HSP World” held in Québec 2-5 October 2014. Twenty-five scientists provided chapters for the book. The chapters are from the best scientists currently working in this field. These colleagues include Arrigo, Benesch, Benjamin, Buchner-Haslbeck-Weinkauf, Benndorf, Boelens, Carra, Chang, Currie, Ecroyd, Emanuelsson, Fu, Garrido, Golenhofen, Gusev, Hightower, Kampinga, Lavoie, MacRae, Quinlan, Tanguay, Vierling, Vigh, Weeks and Wu. Briefly, the book starts with the structure of small heat shock proteins, moving to their functions and finishing with their involvement in diseases. Although this is quite broad, the structural aspect will be the unifying theme of the book.

Heat Shock Proteins and Stress

Author : Alexzander A. A. Asea,Punit Kaur
Publisher : Springer
Page : 315 pages
File Size : 46,8 Mb
Release : 2018-10-24
Category : Science
ISBN : 9783319907253

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Heat Shock Proteins and Stress by Alexzander A. A. Asea,Punit Kaur Pdf

The book Heat Shock Proteins and Stress provides the most comprehensive review on contemporary knowledge on the role of HSP in Stress. Using an integrative approach to understanding the regulation of HSP responses, the contributors provide a synopsis of novel mechanisms by which HSP responses are regulated under normal physiological and pathophysiological conditions. Key basic and clinical research laboratories from major universities and academic medical hospitals around the world contribute chapters that review present research activity and importantly project the field into the future. The book is a must read for researchers, postdoctoral fellows and graduate students in the fields of Translational Medicine, Clinical Psychologists, Human Physiology, Zoologists, Botanists, Biotechnology, Molecular Medicine, Infectious Diseases Experts and Pathologists.

Stress Proteins

Author : Milton J. Schlesinger,M. Gabriella Santoro,Enrico Garaci
Publisher : Springer Science & Business Media
Page : 125 pages
File Size : 46,8 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642758157

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Stress Proteins by Milton J. Schlesinger,M. Gabriella Santoro,Enrico Garaci Pdf

All living organisms are exposed to rapidly changing environmental conditions which may lead to external stress. How organisms cope with stress - especially on the molecular level - is explained in Stress Proteins. Cells react to external stress - where the temperature-induced reaction known as "heat shock response" is the best studied example of stress - by activating special genes and subsequently synthesizing stress proteins. Surprisingly, this stress response is not only similar for all types of stress but even the involved stress proteins are virtually identical in all organisms from prokaryotic to eukaryotic cells, from bacteria to humans. This universality shows that stress proteins are vital for surviving and indicates that these proteins play an essential role in normal cell functions, in cell growth and metabolism. This explains the great interest in stress response research.

Stress Proteins

Author : David S. Latchman
Publisher : Springer Science & Business Media
Page : 436 pages
File Size : 51,5 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642582592

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Stress Proteins by David S. Latchman Pdf

This work is concerned with a group of proteins which were originally consid ered to be an esoteric phenomenon but which have now been shown to play critical roles both in normal and stressed cells as well as being involved in a variety of human diseases. It is the purpose of this work to give a comprehen sive view of these proteins and their various aspects. After an introductory chapter providing an overview of these proteins, the work is divided into four main sections each of which deals with one important aspect of these proteins. Thus, the first section contains a series of chapters which describe individual stress proteins and their roles in particular biological phenomena. Evidently, the induction of these proteins by elevated tempera ture or other stresses is their defining feature and the second section of this book therefore considers the regulation of stress protein gene expression both by stressful stimuli such as elevated temperature or ischaemia and by non stressful stimuli such as cytokines.

Small Stress Proteins and Human Diseases

Author : Stéphanie Simon,André-Patrick Arrigo
Publisher : Nova Science Publishers
Page : 0 pages
File Size : 46,9 Mb
Release : 2012
Category : Heat shock proteins
ISBN : 1614706360

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Small Stress Proteins and Human Diseases by Stéphanie Simon,André-Patrick Arrigo Pdf

Essential for the defence against all kinds of stress, small stress proteins also play major roles in the physiology, development and differentiation of human cells. In spite of their beneficial roles, small stress proteins can also be deleterious for the organism, notably in some cancer pathologies where they can, through their anti-apoptotic properties, favour tumour development and interfere with the cytotoxic activity of anti-cancer drugs. This book proposes a focus on the recent knowledge in the field of the expression and putative role of small stress proteins in human health and diseases.

Heat Shock Proteins in Inflammatory Diseases

Author : Alexzander A. A. Asea,Punit Kaur
Publisher : Springer
Page : 0 pages
File Size : 49,8 Mb
Release : 2022-10-15
Category : Science
ISBN : 3030851702

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Heat Shock Proteins in Inflammatory Diseases by Alexzander A. A. Asea,Punit Kaur Pdf

The book Heat Shock Proteins in Inflammatory Diseases provides the most comprehensive highlight and insight of the expression, function and therapeutic activity of Heat Shock Proteins in inflammatory diseases including sepsis, psoriasis, neurodegenerative diseases, cancers, viral infection and autoimmune rheumatic diseases. Using an integrative approach, the contributors provide a synopsis of the most current updates on the state of HSP in inflammatory diseases. Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed chapters that review present research activity and importantly project the field into the future. The book is a must read for graduate students. medical students, basic science researchers and postdoctoral scholars in the fields of Cancer Biology, Oncology, Translational Medicine, Clinical Research, Biotechnology, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.

Cell Stress Proteins

Author : Stuart K. Calderwood
Publisher : Springer Science & Business Media
Page : 464 pages
File Size : 43,9 Mb
Release : 2009-02-13
Category : Science
ISBN : 9780387397177

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Cell Stress Proteins by Stuart K. Calderwood Pdf

This book surveys the current knowledge concerning the expression and function of stress proteins in different organisms, ranging from prokaryotes to humans. It provides an overview of the diversity and complex evolutionary history of cell stress proteins and describes their function and expression in different eukaryote models. The book will appeal to researchers and scientists in biochemistry, cell biology, microbiology, immunology, and genetics.

Heat Shock Proteins and Plants

Author : Alexzander A. A. Asea,Stuart K. Calderwood,Punit Kaur
Publisher : Springer
Page : 344 pages
File Size : 48,6 Mb
Release : 2016-11-23
Category : Science
ISBN : 9783319463407

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Heat Shock Proteins and Plants by Alexzander A. A. Asea,Stuart K. Calderwood,Punit Kaur Pdf

Heat Shock Proteins and Plants provides the most up-to-date and concise reviews and progress on the role of heat shock proteins in plant biology, structure and function and is subdivided into chapters focused on Small Plant HSPs (Part I), Larger Plant HSPs (Part II) and HSPs for Therapeutic Gain (Part III). This book is written by eminent leaders and experts from around the world and is an important reference book and a must-read for undergraduate, postgraduate students and researchers in the fields of Agriculture, Botany, Crop Research, Plant Genetics and Biochemistry, Biotechnology, Drug Development and Pharmaceutical Sciences.

Molecular Aspects of the Stress Response: Chaperones, Membranes and Networks

Author : Peter Csermely,László Vígh
Publisher : Springer Science & Business Media
Page : 218 pages
File Size : 48,8 Mb
Release : 2007-08-09
Category : Science
ISBN : 9780387399751

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Molecular Aspects of the Stress Response: Chaperones, Membranes and Networks by Peter Csermely,László Vígh Pdf

This book makes a novel synthesis of the molecular aspects of the stress response and long term adaptation processes with the system biology approach of biological networks. Authored by an exciting mixture of top experts and young rising stars, it provides a comprehensive summary of the field and identifies future trends.

Encyclopedic Reference of Molecular Pharmacology

Author : Stefan Offermanns,Walter Rosenthal
Publisher : Unknown
Page : 1152 pages
File Size : 49,7 Mb
Release : 2004
Category : Encyclopedias and dictionaries
ISBN : UOM:39015052659656

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Encyclopedic Reference of Molecular Pharmacology by Stefan Offermanns,Walter Rosenthal Pdf

Presents current information on the molecular mechanisms of drug action. Provides 159 essays describing groups of drugs and drug targets. Several essays deal with general principles of pharmacology, such as drug tolerance, drug addiction, or drug metabolism.

Stress Proteins

Author : H. Abe
Publisher : Springer
Page : 456 pages
File Size : 49,9 Mb
Release : 1999
Category : Medical
ISBN : UOM:39015043186603

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Stress Proteins by H. Abe Pdf

With contributions by numerous experts

Regulation of Heat Shock Protein Responses

Author : Alexzander A A Asea,Punit Kaur
Publisher : Springer
Page : 472 pages
File Size : 46,6 Mb
Release : 2018-05-01
Category : Medical
ISBN : 9783319747156

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Regulation of Heat Shock Protein Responses by Alexzander A A Asea,Punit Kaur Pdf

This books provides the most up-to-date reviews on current advances in our understanding of the regulation of heat shock protein responses. Key basic scientists and clinical research laboratories from major universities, academic medical centers and pharmaceutical companies around the world have contributed chapters that review present research activity and importantly project this field into the future. For easy readability, the book is sub divided into four sections, including, Section I - HSP and Stress Responses; Section II - Chaperone Functions of HSP; Section III - HSP in Human Diseases; Section IV - Prognosis & Diagnosis of HSP. The book is a must read for researchers involved in biomedical research, drug discovery and design to improve human health.

Molecular Chaperones

Author : R.J. Ellis,R.A. Laskey,G.H. Lorimer
Publisher : Springer Science & Business Media
Page : 121 pages
File Size : 44,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789401121088

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Molecular Chaperones by R.J. Ellis,R.A. Laskey,G.H. Lorimer Pdf

Currently one of the hottest topics in biochemistry, the concept of molecular chaperones has challenged the paradigm of protein self-assembly. Key figures in many disciplines review all aspects of molecular chaperones in this volume, which arises from a Royal Society discussion meeting. Overview chapters discuss the significance of chaperones in biochemistry, molecular genetics and cell biology. Each chapter is well referenced providing access to the literature.

Heat Shock Proteins in Cancer

Author : Stuart K. Calderwood,Michael Y. Sherman,Daniel R. Ciocca
Publisher : Springer Science & Business Media
Page : 399 pages
File Size : 51,8 Mb
Release : 2007-09-09
Category : Medical
ISBN : 9781402064012

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Heat Shock Proteins in Cancer by Stuart K. Calderwood,Michael Y. Sherman,Daniel R. Ciocca Pdf

Heat shock proteins are emerging as important molecules in the development of cancer and as key targets in cancer therapy. These proteins enhance the growth of cancer cells and protect tumors from treatments such as drugs or surgery. However, new drugs have recently been developed particularly those targeting heat shock protein 90. As heat shock protein 90 functions to stabilize many of the oncogenes and growth promoting proteins in cancer cells, such drugs have broad specificity in many types of cancer cell and offer the possibility of evading the development of resistance through point mutation or use of compensatory pathways. Heat shock proteins have a further property that makes them tempting targets in cancer immunotherapy. These proteins have the ability to induce an inflammatory response when released in tumors and to carry tumor antigens to antigen presenting cells. They have thus become important components of anticancer vaccines. Overall, heat shock proteins are important new targets in molecular cancer therapy and can be approached in a number of contrasting approaches to therapy.