Snake Venoms

Author : P. Gopalakrishnakone,Hidetoshi Inagaki,Ashis K. Mukherjee,Tarek R. Rahmy,Carl-Wilhelm Vogel
Publisher : Springer
Page : 0 pages
File Size : 40,7 Mb
Release : 2017-02-14
Category : Medical
ISBN : 940076409X

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Snake Venoms by P. Gopalakrishnakone,Hidetoshi Inagaki,Ashis K. Mukherjee,Tarek R. Rahmy,Carl-Wilhelm Vogel Pdf

In recent years, the field of Toxinology has expanded substantially. On the one hand it studies venomous animals, plants and micro organisms in detail to understand their mode of action on targets. While on the other, it explores the biochemical composition, genomics and proteomics of toxins and venoms to understand their three interaction with life forms (especially humans), development of antidotes and exploring their pharmacological potential. Therefore, Toxinology has deep linkages with biochemistry, molecular biology, anatomy and pharmacology. In addition, there is a fast developing applied subfield, clinical toxinology, which deals with understanding and managing medical effects of toxins on human body. Given the huge impact of toxin-based deaths globally, and the potential of venom in generation of drugs for so-far incurable diseases (for example, Diabetes, Chronic Pain), the continued research and growth of the field is imminent. This has led to the growth of research in the area and the consequent scholarly output by way of publications in journals and books. Despite this ever growing body of literature within biomedical sciences, there is still no all-inclusive reference work available that collects all of the important biochemical, biomedical and clinical insights relating to Toxinology. The Handbook of Toxinology aims to address this gap and cover the field of Toxinology comprehensively.

Author : C.-Y. Lee
Publisher : Springer Science & Business Media
Page : 1162 pages
File Size : 48,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642669132

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Snake Venoms by C.-Y. Lee Pdf

The past decade has been a period of explosion of knowledge on the chemistry and pharmacology of snake toxins. Thanks to the development of protein chemistry, nearly a hundred snake toxins have been purified and sequenced, representing one of the largest families of sequenced proteins. Moreover, the mode of action of these toxins has been largely elucidated by the concerted efforts of pharmacologists, electro physiologists, and biochemists. As a result of these studies, some of the snake toxins, e.g., a-bungarotoxin and cobra neurotoxins, have been extensively used as specific markers in the study of the acetylcholine receptors. Indeed, without the discovery of these snake toxins, our knowledge of the structure and function of nicotinic acetylcholine receptors would not have advanced so rapidly. The contribution of snake venom research to the biomedical sciences is not limited to the study of cholinergic receptors. Being one of the most concentrated enzyme sources in nature, snake venoms are also valuable tools in biochemical research. Venom phosphodiesterase, for example, has been widely used for structural studies of nucleic acids; proteinase, for the sequence studies of proteins and pep tides ; phospholipase A , for lipid research; and L-amino acid oxidase for identifying optical z isomers of amino acids. Furthermore, snake venoms have proven to be useful agents for clarifying some basic concepts on blood coagulation and some venom enzymes, e.g., thrombin-like enzymes and pro coagulants have been used as therapeutic agents.

Author : Jean-Philippe Chippaux
Publisher : Krieger Publishing Company
Page : 0 pages
File Size : 47,6 Mb
Release : 2006
Category : Antivenins
ISBN : 1575242729

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Snake Venoms and Envenomations by Jean-Philippe Chippaux Pdf

Presenting a synthesis of the principal discoveries on venoms and envenomations, this text describes the paleontology and classification of snakes as well as the biochemistry and toxicology of venoms to explain the theoretical basis of the envenomation and its treatment.

Author : Hideyo Noguchi
Publisher : Unknown
Page : 452 pages
File Size : 42,9 Mb
Release : 1909
Category : Physiology
ISBN : STANFORD:36105028460355

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Snake Venoms by Hideyo Noguchi Pdf

Author : Jay Fox,José María Gutiérrez
Publisher : MDPI
Page : 277 pages
File Size : 49,9 Mb
Release : 2018-07-10
Category : Electronic
ISBN : 9783038424260

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Snake Venom Metalloproteinases by Jay Fox,José María Gutiérrez Pdf

This book is a printed edition of the Special Issue "Snake Venom Metalloproteinases" that was published in Toxins

Author : Yuri N. Utkin,Arcadius V. Krivoshein
Publisher : Nova Science Publishers
Page : 0 pages
File Size : 48,8 Mb
Release : 2016
Category : Antivenins
ISBN : 1634847431

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Snake Venoms and Envenomation by Yuri N. Utkin,Arcadius V. Krivoshein Pdf

Snake bites are a major health concern, especially in tropical countries. Understanding the pathology of envenomation and chemical composition of snake venoms is important in the development of medical countermeasures (including, but not limited to, antivenoms). Furthermore, snake venoms can be considered natural "combinatorial libraries" of proteins and peptides. Thus, it is not surprising that components of snake venom have been found extensively useful in biomedical research as well as clinical use for treating diseases as diverse as cancer and muscle pain. In this book, well-known scientists from the Americas, Asia, and Europe discuss recent trends and outlooks in regards to snake venom research. A distinctively broader coverage of the subject is given, with topics ranging from protein biochemistry to pathology. Several chapters highlight protein biochemistry and enzymology of snake venoms, immune response to envenomation and antivenoms, production and use of snake venom components as antigens for antivenom preparation, and the therapeutic value of snake venom components in the treatment of various diseases. A comprehensive and authoritative monograph, this book will be equally interesting to both established researchers and graduate students interested in toxinology and pathology of envenomation.

Author : Stephen P. Mackessy
Publisher : CRC Press
Page : 912 pages
File Size : 49,5 Mb
Release : 2021-05-24
Category : Nature
ISBN : 9780429623455

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Handbook of Venoms and Toxins of Reptiles by Stephen P. Mackessy Pdf

A decade after publication of the first edition, Handbook of Venoms and Toxins of Reptiles responds to extensive changes in the field of toxinology to endure as the most comprehensive review of reptile venoms on the market. The six sections of this new edition, which has nearly doubled in size, complement the original handbook by presenting current information from many of the leading researchers and physicians in toxinology, with topics ranging from functional morphology, evolution and ecology to crystallography, -omics technologies, drug discovery and more. With the recent recognition by the World Health Organization of snakebite as a neglected tropical disease, the section on snakebite has been expanded and includes several chapters dealing with the problem broadly and with new technologies and the promises these new approaches may hold to counter the deleterious effects of envenomation. This greatly expanded handbook offers a unique resource for biologists, biochemists, toxicologists, physicians, clinicians, and epidemiologists, as well as informed laypersons interested in the biology of venomous reptiles, the biochemistry and molecular biology of venoms, and the effects and treatment of human envenomation.

Author : Stephen P. Mackessy
Publisher : CRC Press
Page : 548 pages
File Size : 43,7 Mb
Release : 2016-04-19
Category : Medical
ISBN : 9781420008661

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Handbook of Venoms and Toxins of Reptiles by Stephen P. Mackessy Pdf

The Handbook of Venoms and Toxins of Reptiles offers "one-stop shopping" to all biologists, biochemists, toxicologists, physicians, clinicians, and epidemiologists, and informed laypersons interested in the biology of venomous reptiles, the biochemistry and molecular biology of venoms, and the effects and treatment of human envenomation. This book

Author : Hideyo Noguchi
Publisher : Unknown
Page : 436 pages
File Size : 44,5 Mb
Release : 2015-07-21
Category : Science
ISBN : 1331950260

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Snake Venoms by Hideyo Noguchi Pdf

Excerpt from Snake Venoms: An Investigation of Venomous Snakes, With Special Reference to the Phenomena of Their Venoms My interest in an opportunity to study the subject of snake venom I owe to certain peculiar and fortunate circumstances. After my graduation in medicine, I was for several years connected with the Institute for Infectious Diseases, in Tokio, where I came under the instruction of Professor Kitasato. In the autunm of the year 1900 I became assistant in pathology at the University of Pennsylvania, where I remained until Professor Flexner resigned his post to assume the directorship of the laboratories of the Rockefeller Institute. It was soon after my arrival in Philadelphia that Dr.S. Weir Mitchell expressed his great desire that the scientific study of snake venom should be resumed and prosecuted along the lines of the new biological conceptions of toxication and immunity, which had become at that time so promising a field of pathological investigation. I had, therefore, the good fortune thus early to become associated in carrying out the studies (which extended over several years), relating to snake venom, which were issued from the pathological laboratory of the University of Pennsylvania. The expenditure involved in the execution of the researches of snake venom was met first by Dr. Mitchell himself, and later, chiefly through his recommendations, by means granted from the Bache Fund of the National Academy of Sciences and by specific grants from the Carnegie Institution of Washington. During the several years of my connection with the University of Pennsylvania, I was the recipient of many courtesies from the other members of the staff of the Pathological Department, and from Provost Harrison, Dr. John Marshall, the professor of chemistry, and many others, to whom I wish to express my appreciation. In the interval between my leaving the University of Pennsylvania and resuming my connection with Professor Flexner at the Rockefeller Institute, I spent a year of study on snake venom at the Statens Serum Institute, in Copenhagen. The expenses incurred were defrayed by the Carnegie Institution of Washington. For the opportunity to continue my work in the Serum Institute I am indebted to Dr. Madsen, who has also placed me under many obligations by his constant aid and kindness. I am also indebted for many courtesies to Professor Salomonsen and to Dr. Walbum of the Institute. The present monograph on snake venom was projected a number of years ago, and at first it was intended that it should be devoted to a collection of the studies on venom in which I was more or less directly concerned. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.

Author : Sherman A. Minton
Publisher : Marcel Dekker
Page : 208 pages
File Size : 55,9 Mb
Release : 1971
Category : Science
ISBN : UOM:39015001608598

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Snake Venoms and Envenomation by Sherman A. Minton Pdf

Author : Hideyo Noguchi
Publisher : Unknown
Page : 0 pages
File Size : 47,9 Mb
Release : 1909
Category : Serpents
ISBN : LCCN:90023822

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Snake Venoms. An Investigation of Venomous Snakes, with Special Reference to the Phenomena of Their Venoms. [With Thirty-four Plates, and a Bibliography.]. by Hideyo Noguchi Pdf

Author : John Haynes Brown
Publisher : Unknown
Page : 218 pages
File Size : 42,6 Mb
Release : 1973
Category : Poisonous snakes
ISBN : UCSD:31822008827834

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Toxicology and Pharmacology of Venoms from Poisonous Snakes by John Haynes Brown Pdf

Author : Silas Weir Mitchell,Edward Tyson Reichert
Publisher : Unknown
Page : 230 pages
File Size : 55,6 Mb
Release : 1886
Category : Poisonous snakes
ISBN : HARVARD:32044106225204

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Researches Upon the Venoms of Poisonous Serpents by Silas Weir Mitchell,Edward Tyson Reichert Pdf

Author : Bryan Fry
Publisher : Oxford University Press, USA
Page : 609 pages
File Size : 48,8 Mb
Release : 2015
Category : Medical
ISBN : 9780199309399

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Venomous Reptiles and Their Toxins by Bryan Fry Pdf

"Venomous Reptiles And Their Toxins is a comprehensive study of the entire scope of reptile venom, from its evolution to drug design and development. This book devotes a chapter to each toxin class found in reptile venom, detailing the full trajectory of research on the toxin in question. The comprehensive synthesis of research deals with the impact that venom has had on biomedical applications and snake evolution and ecology"--back cover.

Author : Scott A Weinstein,David A. Warrell,Julian White,Daniel E Keyler
Publisher : Elsevier
Page : 364 pages
File Size : 48,8 Mb
Release : 2011-06-20
Category : Medical
ISBN : 9780123877550

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“Venomous Bites from Non-Venomous Snakes by Scott A Weinstein,David A. Warrell,Julian White,Daniel E Keyler Pdf

This book is the first significant contribution to thoroughly examine the potential hazards associated with snakes of the former family, Colubridae. This family contained >65% of living snake species (approximately 3,000 taxa) and has recently been split into multiple families. Many of these snakes produce oral secretions that contain toxins and other biologically-active substances. A large variety of these snakes figure in the pet industry, yet little documented information or formal study of their potential medical importance has been published. Therefore, although the possible medical importance of many of these species has been subjected to speculation since the mid-nineteenth century, there is a limited amount of useful descriptive information regarding the real hazard (or lack thereof) of snakes belonging to this diverse, artificial family. There is a need for "one-stop shopping" offering information regarding their possible toxicity and clinical relevance as well as recommendations for medical management of their bites. This book is the first synthesis of this information and includes evidence-based risk assessment, hazard rankings and specific recommendations regarding important species, many common in captivity. Fills a gap in the toxinological, medical and herpetological literature by providing a comprehensive review of this entire assemblage of snakes, with particular attention given to their capacity, real or rumored, to cause harm to humans A patient-centered, evidence-based approach is applied to analyzing documented case reports of bites inflicted by approximately 100 species. Clinical management of medically significant bites from non-front-fanged colubroids is methodically reviewed, and specific recommendations are provided