Statistical Genetics Of Quantitative Traits

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Statistical Genetics of Quantitative Traits

Rongling Wu,Changxing Ma,George Casella
Statistical Genetics of Quantitative Traits Book PDF

Author : Rongling Wu,Changxing Ma,George Casella
Publisher : Springer Science & Business Media
Page : 371 pages
File Size : 43,9 Mb
Release : 2007-07-17
Category : Science
ISBN : 9780387681542

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Statistical Genetics of Quantitative Traits by Rongling Wu,Changxing Ma,George Casella Pdf

This book introduces the basic concepts and methods that are useful in the statistical analysis and modeling of the DNA-based marker and phenotypic data that arise in agriculture, forestry, experimental biology, and other fields. It concentrates on the linkage analysis of markers, map construction and quantitative trait locus (QTL) mapping, and assumes a background in regression analysis and maximum likelihood approaches. The strength of this book lies in the construction of general models and algorithms for linkage analysis, as well as in QTL mapping in any kind of crossed pedigrees initiated with inbred lines of crops.

Evolution and Selection of Quantitative Traits

Bruce Walsh,Michael Lynch
Evolution and Selection of Quantitative Traits Book PDF

Author : Bruce Walsh,Michael Lynch
Publisher : Oxford University Press
Page : 1504 pages
File Size : 46,5 Mb
Release : 2018-06-21
Category : Science
ISBN : 9780192566645

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Evolution and Selection of Quantitative Traits by Bruce Walsh,Michael Lynch Pdf

Quantitative traits-be they morphological or physiological characters, aspects of behavior, or genome-level features such as the amount of RNA or protein expression for a specific gene-usually show considerable variation within and among populations. Quantitative genetics, also referred to as the genetics of complex traits, is the study of such characters and is based on mathematical models of evolution in which many genes influence the trait and in which non-genetic factors may also be important. Evolution and Selection of Quantitative Traits presents a holistic treatment of the subject, showing the interplay between theory and data with extensive discussions on statistical issues relating to the estimation of the biologically relevant parameters for these models. Quantitative genetics is viewed as the bridge between complex mathematical models of trait evolution and real-world data, and the authors have clearly framed their treatment as such. This is the second volume in a planned trilogy that summarizes the modern field of quantitative genetics, informed by empirical observations from wide-ranging fields (agriculture, evolution, ecology, and human biology) as well as population genetics, statistical theory, mathematical modeling, genetics, and genomics. Whilst volume 1 (1998) dealt with the genetics of such traits, the main focus of volume 2 is on their evolution, with a special emphasis on detecting selection (ranging from the use of genomic and historical data through to ecological field data) and examining its consequences.

Statistical Genetics

Benjamin Neale,Manuel Ferreira,Sarah Medland,Danielle Posthuma
Statistical Genetics Book PDF

Author : Benjamin Neale,Manuel Ferreira,Sarah Medland,Danielle Posthuma
Publisher : Garland Science
Page : 608 pages
File Size : 41,9 Mb
Release : 2007-11-30
Category : Science
ISBN : 9781134129331

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Statistical Genetics by Benjamin Neale,Manuel Ferreira,Sarah Medland,Danielle Posthuma Pdf

Statistical Genetics is an advanced textbook focusing on conducting genome-wide linkage and association analysis in order to identify the genes responsible for complex behaviors and diseases. Starting with an introductory section on statistics and quantitative genetics, it covers both established and new methodologies, providing the genetic and statistical theory on which they are based. Each chapter is written by leading researchers, who give the reader the benefit of their experience with worked examples, study design, and sources of error. The text can be used in conjunction with an associated website (www.genemapping.org) that provides supplementary material and links to downloadable software.

Statistical Genomics

Ben Hui Liu
Statistical Genomics Book PDF

Author : Ben Hui Liu
Publisher : CRC Press
Page : 642 pages
File Size : 46,7 Mb
Release : 2017-11-22
Category : Mathematics
ISBN : 9781351414531

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Statistical Genomics by Ben Hui Liu Pdf

Genomics, the mapping of the entire genetic complement of an organism, is the new frontier in biology. This handbook on the statistical issues of genomics covers current methods and the tried-and-true classical approaches.

Statistical Analysis of Quantitative Genetics

B. L. Agarwal
Statistical Analysis of Quantitative Genetics Book PDF

Author : B. L. Agarwal
Publisher : New Age International
Page : 22 pages
File Size : 46,8 Mb
Release : 2007-12
Category : Breeding
ISBN : 9788122420395

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Statistical Analysis of Quantitative Genetics by B. L. Agarwal Pdf

About the Book: This book deals with the problems of students, teachers and researchers associated with the subject of genetics, plant and animal breeding. Basic concepts necessary to explain statistical measures and analysis of data are also incorporated. Path analysis, heritability, repeatability, genotypic and phenotypic correlations, analysis of breeding experiments by Hayman's approach and otherwise, combining ability analysis for Griffing's models, line x tester analysis, stability analysis etc., are explicated theoretically and also by demonstrating thoroughly worked examples. This book will also bridge the gap between consulting statisticians and breeders. In a broader sense this book is good for students and researchers in the areas of biology, plant breeding, animal breeding, etc., in multifarious ways. Contents: Basics of Genetics Path Analysis Heritability and Repeatability Breeding and Data Analysis Combining Ability Analysis Stability Analysis.

Quantitative Trait Loci

Nicola J. Camp,Angela Cox
Quantitative Trait Loci Book PDF

Author : Nicola J. Camp,Angela Cox
Publisher : Springer Science & Business Media
Page : 362 pages
File Size : 47,8 Mb
Release : 2008-02-03
Category : Medical
ISBN : 9781592591763

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Quantitative Trait Loci by Nicola J. Camp,Angela Cox Pdf

In Quantitative Trait Loci: Methods and Protocols, a panel of highly experienced statistical geneticists demonstrate in a step-by-step fashion how to successfully analyze quantitative trait data using a variety of methods and software for the detection and fine mapping of quantitative trait loci (QTL). Writing for the nonmathematician, these experts guide the investigator from the design stage of a project onwards, providing detailed explanations of how best to proceed with each specific analysis, to find and use appropriate software, and to interpret results. Worked examples, citations to key papers, and variations in method ease the way to understanding and successful studies. Among the cutting-edge techniques presented are QTDT methods, variance components methods, and the Markov Chain Monte Carlo method for joint linkage and segregation analysis.

Statistical Genetics

Prem Narain (Prof.)
Statistical Genetics Book PDF

Author : Prem Narain (Prof.)
Publisher : Unknown
Page : 624 pages
File Size : 49,9 Mb
Release : 1990
Category : Animal breeding
ISBN : STANFORD:36105031239895

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Statistical Genetics by Prem Narain (Prof.) Pdf

This Book Describes The Methodology Of A Field Of Biology That Weds Statistics And Genetics And Goes By The Name Of Statistical Genetics. The Relevant Principles Of Genetics, Statistics And Breeding Are Discussed Together At One Place. The Emphasis Is On The Important Applications Of The Statisticogenetic Principles To The Plant And Animal Breeding Problems. It Has Been Written For The Benefit Of Post- Graduate Students Majoring In The Fields Of Either Genetics And Breeding Or Statistics Applied To Agriculture. Also, Since Advanced Researches In This Field Which Have Taken Place Over The Years Are Scattered In Various Journals, This Book Is Equally Addressed To Researchers In The Fields Of Statistics, Genetics And Breeding.The Book Is Unique In Several Respects And Sets Itself Apart When Compared With Other Published Books On The Subject. The Basic Elements Of Mendelian Genetics Which Is Very Crucial To The Understanding Of The Subject Have Been Included Right In The Beginning. The Relevant Topics Of Population Genetics Essential For Understanding The Principles Of Quantitative Inheritance Have Also Been Dealt With. Special Treatment Has Been Given To The Topics Dealing With The Methods Of Selection And Crossbreeding Which Can Bring About Desired Genetic Improvement. Diallel And Partial Diallel Crosses, Both The Design As Well As The Analysis Aspects Have Been Included.Because Of The Inter-Disciplinary Nature Of The Subject, Bringinng In So To Say Biology And Mathematics Together, The Book Has Adopted An Integrated Approach Placing Due Emphasis On Both The Fields. Appropriate Mathematical And Statistical Derivations For Mathematically Oriented Readers As Also Concepts In Non- Mathematical Terms For Biologist Friends Have Been Presented In A Judicious Manner.

Statistical Methods for QTL Mapping

Zehua Chen
Statistical Methods for QTL Mapping Book PDF

Author : Zehua Chen
Publisher : CRC Press
Page : 308 pages
File Size : 52,6 Mb
Release : 2016-04-19
Category : Mathematics
ISBN : 9781439868317

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Statistical Methods for QTL Mapping by Zehua Chen Pdf

While numerous advanced statistical approaches have recently been developed for quantitative trait loci (QTL) mapping, the methods are scattered throughout the literature. Statistical Methods for QTL Mapping brings together many recent statistical techniques that address the data complexity of QTL mapping. After introducing basic genetics topics an

Genetical Analysis of Quantitative Traits

Dr M Kearsey,Dr H Pooni
Genetical Analysis of Quantitative Traits Book PDF

Author : Dr M Kearsey,Dr H Pooni
Publisher : Garland Science
Page : 396 pages
File Size : 51,7 Mb
Release : 2020-10-29
Category : Science
ISBN : 9781000144178

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Genetical Analysis of Quantitative Traits by Dr M Kearsey,Dr H Pooni Pdf

This text provides a guide to the experimental and analytical methodologies available to study quantitative traits, a review of the genetic control of quantitative traits, and a discussion of how this knowledge can be applied to breeding problems and evolution.

Genetics and Analysis of Quantitative Traits

Michael Lynch,Bruce Walsh
Genetics and Analysis of Quantitative Traits Book PDF

Author : Michael Lynch,Bruce Walsh
Publisher : Sinauer Associates Incorporated
Page : 980 pages
File Size : 53,5 Mb
Release : 1998-01
Category : Science
ISBN : 0878934812

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Genetics and Analysis of Quantitative Traits by Michael Lynch,Bruce Walsh Pdf

Professors Lynch and Walsh bring together the diverse array of theoretical and empirical applications of quantitative genetics in a work that is comprehensive and accessible to anyone with a rudimentary understanding of statistics and genetics.

Phenotypes and Genotypes

Florian Frommlet,Małgorzata Bogdan,David Ramsey
Phenotypes and Genotypes Book PDF

Author : Florian Frommlet,Małgorzata Bogdan,David Ramsey
Publisher : Springer
Page : 222 pages
File Size : 46,5 Mb
Release : 2016-02-12
Category : Computers
ISBN : 9781447153108

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Phenotypes and Genotypes by Florian Frommlet,Małgorzata Bogdan,David Ramsey Pdf

This timely text presents a comprehensive guide to genetic association, a new and rapidly expanding field that aims to elucidate how our genetic code (genotypes) influences the traits we possess (phenotypes). The book provides a detailed review of methods of gene mapping used in association with experimental crosses, as well as genome-wide association studies. Emphasis is placed on model selection procedures for analyzing data from large-scale genome scans based on specifically designed modifications of the Bayesian information criterion. Features: presents a thorough introduction to the theoretical background to studies of genetic association (both genetic and statistical); reviews the latest advances in the field; illustrates the properties of methods for mapping quantitative trait loci using computer simulations and the analysis of real data; discusses open challenges; includes an extensive statistical appendix as a reference for those who are not totally familiar with the fundamentals of statistics.

Principles of Statistical Genomics

Shizhong Xu
Principles of Statistical Genomics Book PDF

Author : Shizhong Xu
Publisher : Springer Science & Business Media
Page : 428 pages
File Size : 53,6 Mb
Release : 2012-09-10
Category : Science
ISBN : 9780387708065

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Principles of Statistical Genomics by Shizhong Xu Pdf

Statistical genomics is a rapidly developing field, with more and more people involved in this area. However, a lack of synthetic reference books and textbooks in statistical genomics has become a major hurdle on the development of the field. Although many books have been published recently in bioinformatics, most of them emphasize DNA sequence analysis under a deterministic approach. Principles of Statistical Genomics synthesizes the state-of-the-art statistical methodologies (stochastic approaches) applied to genome study. It facilitates understanding of the statistical models and methods behind the major bioinformatics software packages, which will help researchers choose the optimal algorithm to analyze their data and better interpret the results of their analyses. Understanding existing statistical models and algorithms assists researchers to develop improved statistical methods to extract maximum information from their data. Resourceful and easy to use, Principles of Statistical Genomics is a comprehensive reference for researchers and graduate students studying statistical genomics.

Introduction to Statistical Methods in Modern Genetics

M.C. Yang
Introduction to Statistical Methods in Modern Genetics Book PDF

Author : M.C. Yang
Publisher : CRC Press
Page : 264 pages
File Size : 52,5 Mb
Release : 2000-02-23
Category : Mathematics
ISBN : 9056991345

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Introduction to Statistical Methods in Modern Genetics by M.C. Yang Pdf

Although the basic statistical theory behind modern genetics is not very difficult, most statistical genetics papers are not easy to read for beginners in the field, and formulae quickly become very tedious to fit a particular area of application. Introduction to Statistical Methods in Modern Genetics distinguishes between the necessary and unnecessary complexity in a presentation designed for graduate-level statistics students. The author keeps derivations simple, but does so without losing the mathematical details. He also provides the required background in modern genetics for those looking forward to entering this arena. Along with some of the statistical tools important in genetics applications, students will learn: How a gene is found How scientists have separated the genetic and environmental aspects of a person's intelligence How genetics are used in agriculture to improve crops and domestic animals What a DNA fingerprint is and why there are controversies about it Although the author assumes students have a foundation in basic statistics, an appendix provides the necessary background beyond the elementary, including multinomial distributions, inference on frequency tables, and discriminant analysis. With clear explanations, a multitude of figures, and exercise sets in each chapter, this text forms an outstanding entrée into the rapidly expanding world of genetic data analysis.

Quantitative Genetics in the Wild

Anne Charmantier,Dany Garant,Loeske E. B. Kruuk
Quantitative Genetics in the Wild Book PDF

Author : Anne Charmantier,Dany Garant,Loeske E. B. Kruuk
Publisher : Oxford University Press, USA
Page : 293 pages
File Size : 51,7 Mb
Release : 2014
Category : Science
ISBN : 9780199674244

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Quantitative Genetics in the Wild by Anne Charmantier,Dany Garant,Loeske E. B. Kruuk Pdf

Although the field of quantitative genetics is almost 100 years old, its application to the study of evolutionary processes in wild populations has expanded greatly over the last few decades.

Likelihood, Bayesian, and MCMC Methods in Quantitative Genetics

Daniel Sorensen,Daniel Gianola
Likelihood Bayesian and MCMC Methods in Quantitative Genetics Book PDF

Author : Daniel Sorensen,Daniel Gianola
Publisher : Springer Science & Business Media
Page : 745 pages
File Size : 51,7 Mb
Release : 2007-03-22
Category : Science
ISBN : 9780387954400

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Likelihood, Bayesian, and MCMC Methods in Quantitative Genetics by Daniel Sorensen,Daniel Gianola Pdf

This book, suitable for numerate biologists and for applied statisticians, provides the foundations of likelihood, Bayesian and MCMC methods in the context of genetic analysis of quantitative traits. Although a number of excellent texts in these areas have become available in recent years, the basic ideas and tools are typically described in a technically demanding style and contain much more detail than necessary. Here, an effort has been made to relate biological to statistical parameters throughout, and the book includes extensive examples that illustrate the developing argument.