Stem Cell Biology In Normal Life And Diseases

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Stem Cell Biology in Normal Life and Diseases

Kamran Alimoghaddam
Stem Cell Biology in Normal Life and Diseases Book PDF

Author : Kamran Alimoghaddam
Publisher : BoD – Books on Demand
Page : 198 pages
File Size : 42,6 Mb
Release : 2013-05-08
Category : Science
ISBN : 9789535111078

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Stem Cell Biology in Normal Life and Diseases by Kamran Alimoghaddam Pdf

Stem cells have a prominent role in normal life and also in pathogenesis of disorders. Today, these cells are clinically applicable in hematopoietic stem cell transplantation but expansion of their application in many more disorders needs more work. For safe and effective application of these cells, we need better knowledge of their biology, their interaction with other cells (especially supporting niche cells), growth, maturation and also immigration of stem cells through body in normal and abnormal conditions. Also for clinical application we need to understand better, their separation methods and safe manipulation. This book is written to clarify some aspects of stem cell biology, their characteristics, assessment of damage to cells during ex vivo manipulation and also their role in a model of cancers (chronic myeloid leukemia).

Stem Cell Biology in Health and Disease

Thomas Dittmar,Kurt S. Zänker
Stem Cell Biology in Health and Disease Book PDF

Author : Thomas Dittmar,Kurt S. Zänker
Publisher : Springer Science & Business Media
Page : 426 pages
File Size : 55,9 Mb
Release : 2009-10-13
Category : Medical
ISBN : 9789048130405

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Stem Cell Biology in Health and Disease by Thomas Dittmar,Kurt S. Zänker Pdf

Stem Cell Biology in Health and Disease presents an up-to-date overview about the dual role of stem cells in health and disease. The Editors have drawn together an international team of experts providing chapters which, in this fully-illustrated volume, discuss: - the controversial debate on the great expectations concerning stem cell based regeneration therapies raised by the pluripotency of various stem cells. - the advantages and concerns about embryonic stem cells (ES cells), induced pluripotent stem cells (iPS cells) and adult stem cells, such as bone marrow-derived stem cells (BMDCs). - the type of stem cells, which has become of interest in the past decade, namely so-called cancer stem cells (CSCs). CSCs are now in the focus of cancer research since the eradication of tumour initiating cells would raise the changes of definitely cure cancer. Professor Dittmar and Professor Zänker have edited a must-read book for researchers and professionals working in the field of regenerative medicine and/or cancer.

The Real Life Story of Stem Cells

Dr. Bhaskar Vyas & Dr. Rajni Vyas
The Real Life Story of Stem Cells Book PDF

Author : Dr. Bhaskar Vyas & Dr. Rajni Vyas
Publisher : Dr. Bhaskar Vyas
Page : 116 pages
File Size : 55,9 Mb
Release : 2020-08-10
Category : Biography & Autobiography
ISBN : 8210379456XXX

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The Real Life Story of Stem Cells by Dr. Bhaskar Vyas & Dr. Rajni Vyas Pdf

This book is an autobiographical narration of the research activities, with penchant and passion, by two leading clinicians who turned towards stem cell research in later years of their life. The book is about facts as they happened, it also includes fiction as it should be a part of any novel and there is fantasizing as well as what one would like to be in the future. Facts, fiction and fantasy are frequently flavoured with philosophy as well. The authors axiomatically classify themselves as philosophers. Advocating that philosophy is the mother of all disciplines, they narrate how they jumped into deep waters of expensive stem cell research. The book describes how did they blunder at times and also cites the appearance of guardian angels to salvage them. Floundering from cell biology to different kinds of stem cell applications, the book describes where they have now parked at a far horizon, on the edge of new discovery of a wonderful drug. They ignite a spark of caution with restrictive regulations. The book ends with reframing the poem by Rabindranath Tagore, ‘Into that heaven of regenerative medicine, my Father, let my country awake.’

Stem Cells and the Future of Regenerative Medicine

Institute of Medicine,Board on Neuroscience and Behavioral Health,National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on the Biological and Biomedical Applications of Stem Cell Research
Stem Cells and the Future of Regenerative Medicine Book PDF

Author : Institute of Medicine,Board on Neuroscience and Behavioral Health,National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on the Biological and Biomedical Applications of Stem Cell Research
Publisher : National Academies Press
Page : 112 pages
File Size : 41,6 Mb
Release : 2002-01-25
Category : Science
ISBN : 9780309170420

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Stem Cells and the Future of Regenerative Medicine by Institute of Medicine,Board on Neuroscience and Behavioral Health,National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on the Biological and Biomedical Applications of Stem Cell Research Pdf

Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.

Cell Biology and Translational Medicine, Volume 6

Kursad Turksen
Cell Biology and Translational Medicine Volume 6 Book PDF

Author : Kursad Turksen
Publisher : Springer Nature
Page : 228 pages
File Size : 43,9 Mb
Release : 2020-01-09
Category : Science
ISBN : 9783030328238

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Cell Biology and Translational Medicine, Volume 6 by Kursad Turksen Pdf

Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the sixth volume of a continuing series.

Adult Stem Cells

Donald G. Phinney
Adult Stem Cells Book PDF

Author : Donald G. Phinney
Publisher : Springer Science & Business Media
Page : 279 pages
File Size : 41,5 Mb
Release : 2011-02-11
Category : Science
ISBN : 9781617790027

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Adult Stem Cells by Donald G. Phinney Pdf

This is comprehensive overview of a vital area of scientific enquiry, which covers a broad spectrum of issues. With contributions from some of the key researchers in the field, Adult Stem Cells: Biology and Methods of Analysis offers readers a historical perspective as well as unique insights into cutting-edge thoughts. The volume contextualizes the recent discovery of stem/progenitor cell populations resident in many adult tissues and organs. It confronts the complexities scientists face in trying to validate these cells, while it also describes and critically evaluates the methods currently used to assess stem cell self-renewal. The chapters also seek to distinguish this process from other aspects of cell survival, such as the regulation of life span, senescence, and immortalization at a molecular level. The monograph begins with a section that examine the basic biology of adult stem cells, including chapters on the emerging role of microRNAs in regulating their fate and the molecular mechanisms that govern their self-renewal, the book moves on to analyze the varying methodologies employed in characterizing these elusive elements of our genetic make-up. The second section details in-vivo lineage tracing of tissue-specific stem cells, explores the neural stem cell paradigm, and considers the function of ABC transporters and aldehyde dehydrogenase in adult stem-cell biology. The final section shifts the focus to the life-span regulation and immortalization and features a chapter on the cancer stem cell paradigm. This is an authoritative volume on one of the frontiers of genetic research, and will serve as a valuable resource, not just for established scientists but also for those now entering the field of stem cell biology.

Stem Cells: An Insider's Guide

Paul Knoepfler
Stem Cells An Insider s Guide Book PDF

Author : Paul Knoepfler
Publisher : World Scientific
Page : 368 pages
File Size : 53,8 Mb
Release : 2013-07-30
Category : Science
ISBN : 9789814508827

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Stem Cells: An Insider's Guide by Paul Knoepfler Pdf

Stem Cells: An Insider's Guide is an exciting new book that takes readers inside the world of stem cells guided by international stem cell expert, Dr. Paul Knoepfler. Stem cells are catalyzing a revolution in medicine. The book also tackles the exciting and hotly debated area of stem cell treatments that are capturing the public's imagination. In the future they may also transform how we age and reproduce. However, there are serious risks and ethical challenges, too. The author's goal with this insider's guide is to give readers the information needed to distinguish between the ubiquitous hype and legitimate hope found throughout the stem cell world. The book answers the most common questions that people have about stem cells. Can stem cells help my family with a serious medical problem such as Alzheimer's, Multiple Sclerosis, or Autism? Are such treatments safe? Can stem cells make me look younger or even literally stay physically young? These questions and many more are answered here.A number of ethical issues related to stem cells that spark debates are discussed, including risky treatments, cloning and embryonic stem cells. The author breaks new ground in a number of ways such as by suggesting reforms to the FDA, providing a new theory of aging based on stem cells, and including a revolutionary Stem Cell Patient Bill of Rights. More generally, the book is your guide to where the stem cell field will be in the near future as well as a thoughtful perspective on how stem cell therapies will ultimately change your life and our world.

Stem Cells and Cancer Stem Cells, Volume 7

M.A. Hayat
Stem Cells and Cancer Stem Cells Volume 7 Book PDF

Author : M.A. Hayat
Publisher : Springer Science & Business Media
Page : 278 pages
File Size : 49,7 Mb
Release : 2012-06-12
Category : Medical
ISBN : 9789400742857

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Stem Cells and Cancer Stem Cells, Volume 7 by M.A. Hayat Pdf

The seventh in Springer’s landmark series of edited volumes on one of the highest-profile subjects in contemporary medicine and scientific endeavour, this volume sets out to cover a staggering range of research into the medical applications of stem cell research. While stem cells are the very stuff of life for multicellular organisms, including us humans, the cancer stem cell is a morbid entity with a robust resistance to therapies including conventional chemotherapy. This authoritative publication explains the regenerative potential of stem cells and their mesenchymal progeny, reviewing clinical applications of the latter in the treatment of cancer, diabetes and neurodegenerative pathologies. It covers the entire range of stem cells with known potential for therapeutic use, from human embryonic to germ cell-derived pluripotent stem cells and hematopoietic stem cells. The chapters also deal with the role of TGF-beta in propagating human embryonic stem cells, and in facilitating their differentiation. Featuring discussions of molecular signaling pathways that modulate mesenchymal stem cell self-renewal and much more, this book is certain to have broad appeal among academicians and physicians alike.

Cell Biology and Translational Medicine, Volume 5

Kursad Turksen
Cell Biology and Translational Medicine Volume 5 Book PDF

Author : Kursad Turksen
Publisher : Springer
Page : 172 pages
File Size : 46,9 Mb
Release : 2019-05-22
Category : Science
ISBN : 9783030175894

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Cell Biology and Translational Medicine, Volume 5 by Kursad Turksen Pdf

Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the fifth volume of a continuing series.

Essentials of Stem Cell Biology

Robert Lanza,John Gearhart,Brigid Hogan,Douglas Melton,Roger Pedersen,E. Donnall Thomas,James A. Thomson,Ian Wilmut
Essentials of Stem Cell Biology Book PDF

Author : Robert Lanza,John Gearhart,Brigid Hogan,Douglas Melton,Roger Pedersen,E. Donnall Thomas,James A. Thomson,Ian Wilmut
Publisher : Academic Press
Page : 681 pages
File Size : 53,5 Mb
Release : 2009-06-05
Category : Science
ISBN : 9780080884974

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Essentials of Stem Cell Biology by Robert Lanza,John Gearhart,Brigid Hogan,Douglas Melton,Roger Pedersen,E. Donnall Thomas,James A. Thomson,Ian Wilmut Pdf

First developed as an accessible abridgement of the successful Handbook of Stem Cells, Essentials of Stem Cell Biology serves the needs of the evolving population of scientists, researchers, practitioners and students that are embracing the latest advances in stem cells. Representing the combined effort of seven editors and more than 200 scholars and scientists whose pioneering work has defined our understanding of stem cells, this book combines the prerequisites for a general understanding of adult and embryonic stem cells with a presentation by the world's experts of the latest research information about specific organ systems. From basic biology/mechanisms, early development, ectoderm, mesoderm, endoderm, methods to application of stem cells to specific human diseases, regulation and ethics, and patient perspectives, no topic in the field of stem cells is left uncovered. Selected for inclusion in Doody's Core Titles 2013, an essential collection development tool for health sciences libraries Contributions by Nobel Laureates and leading international investigators Includes two entirely new chapters devoted exclusively to induced pluripotent stem (iPS) cells written by the scientists who made the breakthrough Edited by a world-renowned author and researcher to present a complete story of stem cells in research, in application, and as the subject of political debate Presented in full color with glossary, highlighted terms, and bibliographic entries replacing references

The SAGE Encyclopedia of Stem Cell Research

Eric E. Bouhassira
The SAGE Encyclopedia of Stem Cell Research Book PDF

Author : Eric E. Bouhassira
Publisher : SAGE Publications
Page : 1517 pages
File Size : 43,6 Mb
Release : 2015-06-15
Category : Medical
ISBN : 9781483347677

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The SAGE Encyclopedia of Stem Cell Research by Eric E. Bouhassira Pdf

The SAGE Encyclopedia of Stem Cell Research, Second Edition is filled with new procedures and exciting medical breakthroughs, including executive orders from the Obama administration reversing barriers to research imposed under the Bush administration, court rulings impacting NIH funding of research based on human embryonic stem cells, edicts by the Papacy and other religious leaders, and the first success in cloning human stem cells. Stem cell biology is clearly fueling excitement and potential in traditional areas of developmental biology and in the field of regenerative medicine, where they are believed to hold much promise in addressing any number of intractable medical conditions. This updated second edition encyclopedia will expand on information that was given in the first edition and present more than 270 new and updated articles that explore major topics in ways accessible to nonscientists, thus bringing readers up-to-date with where stem cell biology stands today, including new and evolving ethical, religious, legal, social, and political perspectives. This second edition reference work will serve as a universal resource for all public and academic libraries. It is an excellent foundation for anyone who is interested in the subject area of stem cell biology. Key Features: Reader’s Guide, Further Readings, Cross References, Chronology, Resource Guide, Index A Glossary will elucidate stem cell terminology for the nonscientist Statistics and selected reprints of major journal articles that pertain to milestones achieved in stem cell research Documents from Congressional Hearings on stem cells and cloning Reports to the President’s Council on Bioethics, and more

Hematopoietic Stem Cell Biology

Motonari Kondo
Hematopoietic Stem Cell Biology Book PDF

Author : Motonari Kondo
Publisher : Springer Science & Business Media
Page : 252 pages
File Size : 53,5 Mb
Release : 2009-12-04
Category : Medical
ISBN : 9781603273473

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Hematopoietic Stem Cell Biology by Motonari Kondo Pdf

In the summer of 1988, my developmental biology professor announced to the class that hematopoietic stem cells (HSCs) had finally been purified. Somehow, I never forgot the professor’s words. When I started working in Dr. Irv Weissman’s labo- tory at Stanford as a postdoctoral fellow, I realized that the findings mentioned by the professor were from Weissman’s laboratory and had been published in a 1988 edition of the journal Science. It has been over 20 years since the publication of that seminal paper, and since then tremendous advances in understanding the biology and maturation of HSCs, namely the process of hematopoiesis, which includes lymphocyte development, have been made. These discoveries were made possible in part by advancements in technology. For example, recent availability of user friendly fluorescence activated cell sorting (FACS) machines and monoclonal an- bodies with a variety of fluorescent labels has allowed more scientists to sort and analyze rare populations in the bone marrow, such as HSCs. All classes of hematopoietic cells are derived from HSCs. Stem cell biology draws enormous attention not only from scientists, but also from ordinary people because of the tremendous potential for development of new therapeutic application to diseases that currently lack any type of effective therapy. Thus, this type of “regenerative medicine” is a relatively new and attractive field in both basic science and clinical medicine.

Stem Cells: Biology and Diseases

Rex Turner
Stem Cells Biology and Diseases Book PDF

Author : Rex Turner
Publisher : Unknown
Page : 0 pages
File Size : 54,5 Mb
Release : 2015-03-12
Category : Electronic
ISBN : 1632413612

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Stem Cells: Biology and Diseases by Rex Turner Pdf

This book comprehensively discusses topics like biology and diseases related to the field of stem cells. Stem cells play an important role in our normal life as well as in the pathogenesis of disorders. Currently, these cells are clinically applicable in

Cell Biology and Translational Medicine, Volume 9

Kursad Turksen
Cell Biology and Translational Medicine Volume 9 Book PDF

Author : Kursad Turksen
Publisher : Springer
Page : 163 pages
File Size : 48,5 Mb
Release : 2020-08-28
Category : Science
ISBN : 303054916X

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Cell Biology and Translational Medicine, Volume 9 by Kursad Turksen Pdf

Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the ninth volume of a continuing series.

Essential Current Concepts in Stem Cell Biology

Beate Brand-Saberi
Essential Current Concepts in Stem Cell Biology Book PDF

Author : Beate Brand-Saberi
Publisher : Springer Nature
Page : 247 pages
File Size : 51,7 Mb
Release : 2020-01-03
Category : Medical
ISBN : 9783030339234

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Essential Current Concepts in Stem Cell Biology by Beate Brand-Saberi Pdf

This textbook describes the biology of different adult stem cell types and outlines the current level of knowledge in the field. It clearly explains the basics of hematopoietic, mesenchymal and cord blood stem cells and also covers induced pluripotent stem cells. Further, it includes a chapter on ethical aspects of human stem cell research, which promotes critical thinking and responsible handling of the material. Based on the international masters program Molecular and Developmental Stem Cell Biology taught at Ruhr-University Bochum and Tongji University Shanghai, the book is a valuable source for postdocs and researchers working with stems cells and also offers essential insights for physicians and dentists wishing to expand their knowledge. This textbook is a valuable complement to Concepts and Applications of Stem Cell Biology, also published in the Learning Materials in Biosciences textbook series.