Stem Cells A Cellular Fountain Of Youth

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Stem Cells: A Cellular Fountain of Youth

M.P. Mattson,G. van Zant
Stem Cells A Cellular Fountain of Youth Book PDF

Author : M.P. Mattson,G. van Zant
Publisher : Elsevier
Page : 240 pages
File Size : 43,9 Mb
Release : 2002-08-21
Category : Medical
ISBN : 0444507310

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Stem Cells: A Cellular Fountain of Youth by M.P. Mattson,G. van Zant Pdf

The developmental capabilities and therapeutic potential of stem cells are being revealed in studies of cellular signaling mechanisms that regulate their proliferation, differentiation and survival. "Stem Cells: A Cellular Fountain of Youth" reviews the current state of understanding of the molecular mechanisms that regulate embryonic and adult stem cells with an emphasis on how aging and age-related disease impact on these mechanisms. Leading authorities detail the properties and therapeutic potential of embryonic stem cells, and stem cell precursors of blood, nervous and muscle and bone cells. Recent advances in deciphering the environmental signals and intrinsic signal transduction pathways that regulate embryonic stem cells are described, and the potential therapeutic uses of these totipotent cells is considered. Analyses of hematopoietic stem cells during aging suggest an important genetic component to the control of their self-renewing capability which may contribute to determination of lifespan. The contribution of lymphocyte depletion to impaired immune function during aging is considered, as is the potential of hematopoietic cells to form other types of cells including neurons. Several chapters cover the remarkable and rapidly advancing field of neural stem cells. The adult brain contains populations of stem cells capable of forming new neurons and glial cells; the signals that regulate these neural stem cells and the involvement of neurogenesis in normal brain function is described. Because of their potential to replace lost or damaged neurons, there has been intense interest in determining the therapeutic potential of stem cells for the treatment of patients with Parkinson's and Alzheimer's diseases, stroke and traumatic brain and spinal cord injuries. Heart and skeletal muscle contain stem cells and the impact of aging and disease on these stem cell populations and the potential of stem cell therapy to recover function of these organs is reviewed. A final example of the fascinating world of stem cells is a review of the roles of stem cells in bone formation and remodeling. Collectively, this book provides a comprehensive, yet concise, view of stem cell molecular biology in the context of aging and age-related disease. This book will be a valuable reference for graduate students and senior scientists interested in the fascinating world of stem cells and their potential use in the clinic.

Stem Cells

Dr Paul Lapena Casingal
Stem Cells Book PDF

Author : Dr Paul Lapena Casingal
Publisher : Unknown
Page : 126 pages
File Size : 43,6 Mb
Release : 2018-09-17
Category : Science
ISBN : 1644403730

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Stem Cells by Dr Paul Lapena Casingal Pdf

Stem Cells have fascinated scientists, doctors, and now the public. Stem cells are blank or undifferentiated cells that turn in to specialized cells and tissues in the area of the body that they are introduced.

Golden Cell

Karen Van Kampen
Golden Cell Book PDF

Author : Karen Van Kampen
Publisher : HarperCollins Canada
Page : 350 pages
File Size : 54,5 Mb
Release : 2010-05-25
Category : Science
ISBN : 9781443400053

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Golden Cell by Karen Van Kampen Pdf

The promise of a regenerative medicine -- the regrowth of lost limbs and organs, new hope for patients with Alzheimer's or multiple sclerosis, the "cellular fountain of youth" -- sounds like science fiction, but it's real and on the cutting edge of medicine. Veteran medical journalist Karen van Kamped looks at this new technology through the stories of the scientists who are creating it and the ethical and legal questions with which they must deal. Many companies and universities in Canada are at the forefront of cellular research, and this fascinating book shows that the next frontier of medicine is unfolding around us.

Stem Cells Using the Bodies Own Cells to Treat Injuries, Reverse Aging and Now Regrow Hair

John Satino
Stem Cells Using the Bodies Own Cells to Treat Injuries Reverse Aging and Now Regrow Hair Book PDF

Author : John Satino
Publisher : Unknown
Page : 24 pages
File Size : 50,6 Mb
Release : 2017-08-23
Category : Science
ISBN : 1543444849

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Stem Cells Using the Bodies Own Cells to Treat Injuries, Reverse Aging and Now Regrow Hair by John Satino Pdf

Since the beginning of time, we have been looking for the fountain of youth. This has opened the doors for charlatans and con men, thought out the centuries, to separate us from our gold and silver, with promises of eternal youth. The prime example in the eighteen hundreds was the medicine wagons traveling across the parries, offering entertainment, and curing for everything from gout to baldness.

Handbook of Stem Cells

Robert Paul Lanza
Handbook of Stem Cells Book PDF

Author : Robert Paul Lanza
Publisher : Gulf Professional Publishing
Page : 896 pages
File Size : 41,8 Mb
Release : 2004
Category : Medical
ISBN : 0124366414

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Handbook of Stem Cells by Robert Paul Lanza Pdf

Accompanying CD-ROM (in v. 2) has image collections which can be saved in PowerPoint or HTML.

Handbook of Stem Cells, Two-Volume Set

Robert Lanza,Helen Blau,John Gearhart,Brigid Hogan,Douglas Melton,Malcolm Moore,Roger Pedersen,E. Donnall Thomas,James A. Thomson,Catherine Verfaillie,Irving Weissman,Michael D. West
Handbook of Stem Cells Two Volume Set Book PDF

Author : Robert Lanza,Helen Blau,John Gearhart,Brigid Hogan,Douglas Melton,Malcolm Moore,Roger Pedersen,E. Donnall Thomas,James A. Thomson,Catherine Verfaillie,Irving Weissman,Michael D. West
Publisher : Elsevier
Page : 1760 pages
File Size : 50,9 Mb
Release : 2004-10-05
Category : Science
ISBN : 0080533736

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Handbook of Stem Cells, Two-Volume Set by Robert Lanza,Helen Blau,John Gearhart,Brigid Hogan,Douglas Melton,Malcolm Moore,Roger Pedersen,E. Donnall Thomas,James A. Thomson,Catherine Verfaillie,Irving Weissman,Michael D. West Pdf

New discoveries in the field of stem cell research have frequently appeared in the news and in scientific literature. Research in this area promises to lead to new therapies for cancer, heart disease, diabetes, and a wide variety of other diseases. This two-volume reference integrates this exciting area of biology, combining the prerequisites for a general understanding of adult and embryonic stem cells, the tools, methods, and experimental protocols needed to study and characterize stem cells and progenitor populations, as well as a presentation by the world's experts of what is currently known about each specific organ system. The editors of the Handbook of Stem Cells include: Robert Lanza, Helen Blau, John Gearhart, Brigid Hogan, Douglas Melton, Malcolm Moore, Roger Pedersen, E. Donnall Thomas, James Thomson, Catherine Verfaillie, Irving Weissman, and Michael West. The Editorial Board includes: W. French Anderson, Peter Andrews, Anthony Atala, Jose Cibelli, Giulio Cossu, Robert Edwards, Martin Evans, Elaine Fuchs, Margaret Fuller, Fred Gage, Richard Gardner, Margaret Goodell, Ronald Green, William Haseltine, Joseph Itskovitz-Eldor, Rudolf Jaenisch, Ihor Lemischka, Dame Anne McLaren, Richard Mulligan, Stuart Orkin, Martin Pera, Benjamin Reubinoff, Janet Rossant, Hans Scholer, Austin Smith, Evan Snyder, Davor Solter, Alan Trounson, and Leonard Zon. This comprehensive set should be a much-needed addition to the library of students and researchers alike. * Provides comprehensive coverage on this highly topical subject * Contains contributions by the foremost authorities and premiere names in the field of stem cell research * The accompanying CD-ROM includes over 250 color figures

Progress in Stem Cell Research

Prasad S. Koka
Progress in Stem Cell Research Book PDF

Author : Prasad S. Koka
Publisher : Nova Publishers
Page : 264 pages
File Size : 51,6 Mb
Release : 2008
Category : Medical
ISBN : 1604560657

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Progress in Stem Cell Research by Prasad S. Koka Pdf

Among the many applications of stem cell research are nervous system diseases, diabetes, heart disease, autoimmune diseases as well as Parkinson's disease, end-stage kidney disease, liver failure, cancer, spinal cord injury, multiple sclerosis, Parkinson's disease, and Alzheimer's disease. Stem cells are self-renewing, unspecialised cells that can give rise to multiple types all of specialised cells of the body. Stem cell research also involves complex ethical and legal considerations since they involve adult, foetal tissue and embryonic sources. This new book presents the latest research from around the globe.

Stem Cells

Jacqueline Langwith
Stem Cells Book PDF

Author : Jacqueline Langwith
Publisher : Greenhaven Publishing
Page : 0 pages
File Size : 48,6 Mb
Release : 2012
Category : Young Adult Nonfiction
ISBN : 0737757590

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Stem Cells by Jacqueline Langwith Pdf

Each title in the highly acclaimed Opposing Viewpoints series explores a specific issue by placing expert opinions in a unique pro/con format; the viewpoints are selected from a wide range of highly respected and often hard-to-find publications.;; "Each volume in the Opposing Viewpoints Series could serve as a model not only providing access to a wide diversity of opinions, but also stimulating readers to do further research for group discussion and individual interest. Both shrill and moderate, th"

Stem Cells and Revascularization Therapies

Hyunjoon Kong,Andrew J. Putnam,Lawrence B. Schook
Stem Cells and Revascularization Therapies Book PDF

Author : Hyunjoon Kong,Andrew J. Putnam,Lawrence B. Schook
Publisher : CRC Press
Page : 342 pages
File Size : 42,7 Mb
Release : 2011-12-13
Category : Medical
ISBN : 9781439803240

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Stem Cells and Revascularization Therapies by Hyunjoon Kong,Andrew J. Putnam,Lawrence B. Schook Pdf

In the last few decades, significant advancements in the biology and engineering of stem cells have enabled progress in their clinical application to revascularization therapies. Some strategies involve the mobilization of endogenous stem cell populations, and others employ cell transplantation. However, both techniques have benefited from multidis

Stem Cells

Paul Knoepfler
Stem Cells Book PDF

Author : Paul Knoepfler
Publisher : World Scientific
Page : 368 pages
File Size : 50,8 Mb
Release : 2013
Category : Science
ISBN : 9789814508810

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Stem Cells by Paul Knoepfler Pdf

Stem Cells: An Insider's Guide is an exciting new book that takes readers inside the world of stem cells guided by international stem cell expert, Dr. Paul Knoepfler. Stem cells are catalyzing a revolution in medicine. The book also tackles the exciting and hotly debated area of stem cell treatments that are capturing the public's imagination. In the future they may also transform how we age and reproduce. However, there are serious risks and ethical challenges, too. The author's goal with this insider's guide is to give readers the information needed to distinguish between the ubiquitous hype and legitimate hope found throughout the stem cell world. The book answers the most common questions that people have about stem cells. Can stem cells help my family with a serious medical problem such as Alzheimer's, Multiple Sclerosis, or Autism Are such treatments safe Can stem cells make me look younger or even literally stay physically young These questions and many more are answered here. A number of ethical issues related to stem cells that spark debates are discussed, including risky treatments, cloning and embryonic stem cells. The author breaks new ground in a number of ways such as by suggesting reforms to the FDA, providing a new theory of aging based on stem cells, and including a revolutionary Stem Cell Patient Bill of Rights. More generally, the book is your guide to where the stem cell field will be in the near future as well as a thoughtful perspective on how stem cell therapies will ultimately change your life and our world.

Differentiation of Embryonic Stem Cells

Anonim
Differentiation of Embryonic Stem Cells Book PDF

Author : Anonim
Publisher : Elsevier
Page : 509 pages
File Size : 43,6 Mb
Release : 2003-12-18
Category : Science
ISBN : 0080546161

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Differentiation of Embryonic Stem Cells by Anonim Pdf

This volume covers all aspects of embryonic stem cell differentiation, including mouse embryonic stem cells, mouse embryonic germ cells, monkey and human embryonic stem cells, and gene discovery. * Early commitment steps and generation of chimeric mice * Differentiation to mesoderm derivatives * Gene discovery by manipulation of mouse embryonic stem cells

Mesenchymal Stem Cell Therapy

Lucas G. Chase,Mohan C Vemuri
Mesenchymal Stem Cell Therapy Book PDF

Author : Lucas G. Chase,Mohan C Vemuri
Publisher : Springer Science & Business Media
Page : 458 pages
File Size : 42,7 Mb
Release : 2012-12-12
Category : Science
ISBN : 9781627032001

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Mesenchymal Stem Cell Therapy by Lucas G. Chase,Mohan C Vemuri Pdf

Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host disease, Crohn’s disease, diabetes, multiple sclerosis, critical limb ischemia and many others. MSCs were first identified by Friendenstein and colleagues as an adherent stromal cell population within the bone marrow with the ability to form clonogenic colonies in vitro. In regards to the basic biology associated with MSCs, there has been tremendous progress towards understanding this cell population’s phenotype and function from a range of tissue sources. Despite enormous progress and an overall increased understanding of MSCs at the molecular and cellular level, several critical questions remain to be answered in regards to the use of these cells in therapeutic applications. Clinically, both autologous and allogenic approaches for the transplantation of MSCs are being explored. Several of the processing steps needed for the clinical application of MSCs, including isolation from various tissues, scalable in vitro expansion, cell banking, dose preparation, quality control parameters, delivery methods and numerous others are being extensively studied. Despite a significant number of ongoing clinical trials, none of the current therapeutic approaches have, at this point, become a standard of care treatment. Although exceptionally promising, the clinical translation of MSC-based therapies is still a work in progress. The extensive number of ongoing clinical trials is expected to provide a clearer path forward for the realization and implementation of MSCs in regenerative medicine. Towards this end, reviews of current clinical trial results and discussions of relevant topics association with the clinical application of MSCs are compiled in this book from some of the leading researchers in this exciting and rapidly advancing field. Although not absolutely all-inclusive, we hope the chapters within this book can promote and enable a better understanding of the translation of MSCs from bench-to-bedside and inspire researchers to further explore this promising and quickly evolving field.

The Stem Cell Hope

Alice Park
The Stem Cell Hope Book PDF

Author : Alice Park
Publisher : Penguin Group
Page : 337 pages
File Size : 45,7 Mb
Release : 2012-06-26
Category : Science
ISBN : 9780452297968

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The Stem Cell Hope by Alice Park Pdf

A landmark book by the senior science writer at Time magazine introduces us to a medical breakthrough that can save our lives. Few people know much about stem cell research beyond the ethical questions raised by using embryos. But in the last decade, stem cell research has made huge advances toward eliminating some of our most intractable diseases. Now this sweeping and accessible book introduces us to this cutting-edge science that will revolutionize medicine and change the way we think about and treat disease. Alice Park takes us from stem cell's controversial beginnings to the recent electrifying promise of being able to create the versatile cells without using embryos at all. She shows us how stem cells give researchers an unprecedented ability to study disease while giving patients the promise of replacing diseased cells with healthy new ones. And she profiles the scientists and leaders-many with their own compelling stories-who have fueled the quest and will continue to shape the field in years to come.

Neural Stem Cells for Brain and Spinal Cord Repair

Tanja Zigova
Neural Stem Cells for Brain and Spinal Cord Repair Book PDF

Author : Tanja Zigova
Publisher : Springer Science & Business Media
Page : 434 pages
File Size : 55,5 Mb
Release : 2002-11-05
Category : Medical
ISBN : 9781592592982

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Neural Stem Cells for Brain and Spinal Cord Repair by Tanja Zigova Pdf

Active neuroscientists survey NSCs as potential tools for central nervous system and spinal cord repair by explaining their clinically significant fundamental properties, manipulations, and potential therapeutic paradigms. Their discussion of the fundamental biology of NSCs illustrates the signaling pathways that regulate stem cell division and differentiation, and defines the methods of NSC expansion and propagation, neuromorphogenesis, the factors determining cell fate both in vitro and in situ, and the induction of self-reparative processes within the brain. They also present strategies that may lead to fruitful clinical applications in the near future. These range from the replacement of degenerated, dysfunctional, or maldeveloped cells to the provision of factors that may protect, correct, recruit, promote self-repair, or mediate the connectivity of host cells.

Stem Cells Research Compendium

Prasad S. Koka
Stem Cells Research Compendium Book PDF

Author : Prasad S. Koka
Publisher : Nova Publishers
Page : 462 pages
File Size : 41,5 Mb
Release : 2008
Category : Cell culture
ISBN : 1604565993

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Stem Cells Research Compendium by Prasad S. Koka Pdf

The two broad categories of mammalian stem cells exist: embryonic stem cells, derived from blastocysts, and adult stem cells, which are found in adult tissues. In a developing embryo, stem cells are able to differentiate into all of the specialised embryonic tissues. In adult organisms, stem cells and progenitor cells act as a repair system for the body, replenishing specialised cells. As stem cells can be readily grown and transformed into specialised tissues such as muscles or nerves through cell culture, their use in medical therapies has been proposed. In particular, embryonic cell lines, autologous embryonic stem cells generated therapeutic cloning, and highly plastic adult stem cells from the umbilical cord blood or bone marrow are touted as promising candidates. Among the many applications of stem cell research are nervous system diseases, diabetes, heart disease, autoimmune diseases as well as Parkinson's disease, end-stage kidney disease, liver failure, cancer, spinal cord injury, multiple sclerosis, and Alzheimer's disease. Stem cells are self-renewing, unspecialised cells that can give rise to multiple types all of specialised cells of the body. Stem cell research also involves complex ethical and legal considerations since they involve adult, foetal tissue and embryonic sources. This book presents leading research from around the world in this field which is of interest to so many and presents so many hopes.