Stereochemical Aspects Of Organolithium Compounds

Author : Robert E. Gawley
Publisher : John Wiley & Sons
Page : 305 pages
File Size : 53,9 Mb
Release : 2010-04-16
Category : Science
ISBN : 9783906390635

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Stereochemical Aspects of Organolithium Compounds by Robert E. Gawley Pdf

Topics in Stereochemistry, previously edited by "the father of stereochemistry" Ernest L. Eliel, is a longstanding, successful series covering the most important advances in the field. The much-anticipated Volume 26 on stereochemical aspects of organolithium compounds includes chapters on the following topics: * Asymmetric Deprotonations Using Chiral Lithium Amide Bases * Self-Regeneration of Stereocenters (SRS) via Stereolabile Axially Chiral Intermediates * Overview of Carbanion Dynamics and Electrophilic Substitutions in Chiral Organolithium Compounds * Oxiranyllithiums as Chiral Synthons for Asymmetric Synthesis * Test on the Configurational Stability/Lability of Organolithium Compounds * Mechanism and Stereochemical Features in Asymmetric Deprotonation Using RLi/(-)-Sparteine Bases * Dynamic Resolutions of Chiral Organolithiums Volume 26 of Topics in Stereochemistry marks the end of an era, while developing a bridge to the next generation. A new generation in publishing, parallel to a new generation in Stereochemistry mandated a new venue and modus operandi for Topics. Zurich, the home of Werner and Wislicenus, has a unique heritage in Stereochemistry. Fortunately, the Wiley family's publishing partnerships include Verlag Helvetica Chimica Acta, a house with a reputation for superior quality in publishing. Indeed, within the pages of its namesake periodical, Helvetica Chimica Acta, one finds many of the seminal research works of stereochemistry's giants. As such, a transfer of editorial operations to Zurich and a collaboration bringing Topics as a series closer to periodical status provides a growth platform for the future.

Author : B. J. Wakefield
Publisher : Elsevier
Page : 348 pages
File Size : 50,5 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483278704

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The Chemistry of Organolithium Compounds by B. J. Wakefield Pdf

The Chemistry of Organolithium Compounds is a comprehensive review of the status of organolithium compound chemistry. This book is composed of four parts and nineteen chapters that particularly describe the reactions involving these compounds The first part highlights the constitution of organolithium compounds, specifically in the absence and presence of electron donors, as well as the configurational stability of these compounds. The second part deals with their preparation from organic halides and lithium metal involving metallation and metal-halogen exchange, while the third part focuses on their organic synthesis. The fourth part considers the synthesis of organometallic compound derivatives from main group and transition metals. This book will prove useful to organic chemists and organic chemistry researchers.

Author : Philip Page
Publisher : Academic Press
Page : 309 pages
File Size : 47,6 Mb
Release : 1997-10-17
Category : Science
ISBN : 0080538207

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Synthetic and Stereochemical Aspects by Philip Page Pdf

The impact of organosulfur chemistry, especially in the areas of heterocyclic chemistry, stereocontrolled processes, and asymmetric synthesis, has led to a resurgence of interest in the field. This book is the secondin a series intended to provide coverage of topics of current interest throughout the whole range of organosulfur chemistry. Each volume is comprised of five or six chapters, each consisting of an in-depth, self-contained review in a well-defined area. This volume and its predecessor Organosulfur Chemistry, Synthetic Aspects will prove valuable references for researchers and practitioners in organic chemistry. Methods of asymmetric sulfur oxidation processes Preparation of chiral sulfoxides in nucleophilic displacement at sulfur Conformational preferences of the sulfinyl group Preparation and chemistry of unsaturated sulfoxides Applications of sulfoxides as stereocontrol elements The chemistry of sulfolenes

Author : Michael North
Publisher : Routledge
Page : 262 pages
File Size : 43,8 Mb
Release : 2017-10-19
Category : Medical
ISBN : 9781351422062

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Principles and Applications of Stereochemistry by Michael North Pdf

A thorough understanding of stereochemistry is essential for the comprehension of almost all aspects of modern organic chemistry. It is also of great significance in many biochemical and medicinal disciplines, since the stereoisomers of a compound can have dramatically different biological properties. This text explains how the different properties of stereoisomers of a compound arise, and what processes can be used to prepare and analyze stereoisomerically pure compounds. It also presents prominent coverage of the stereochemistry of inorganic and organometallic compounds, which is likely to increase in importance, as these compounds are used as symmetric catalysts in asymmetric synthesis. Modern stereochemical terminology is used throughout, although reference is also made to older terms which are still widely used. A set of problems at the end of each chapter aims to further the reader's understanding of how the content can be applied. The book is designed mainly as a textbook for undergraduate students and as a reference source for more advanced levels, but is also intended for academic and professional organic chemists.

Author : Zvi Rappoport,Ilan Marek
Publisher : John Wiley & Sons
Page : 1400 pages
File Size : 52,8 Mb
Release : 2004-08-20
Category : Science
ISBN : 9780470021101

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The Chemistry of Organolithium Compounds by Zvi Rappoport,Ilan Marek Pdf

This is the first volume in the series to concentrate on organo-lithium compounds - the sub series "The chemistry of the metal-carbon bond" (5 vol) treated organometallics in general. It deals with theoretical/physical/computational apsects, as well as major spectroscopies, such as MS, NMR, IR/UV etc and both biological and industrial applications. The core of the volume is the synthetic chapters with lots of examples for modern synthetic approaches Written by key researchers in the field An invaluable reference source to organic chemists working in academia and industry Features important reagents in organic synthesis

Author : Renzo Luisi,Vito Capriati
Publisher : John Wiley & Sons
Page : 705 pages
File Size : 42,9 Mb
Release : 2014-03-11
Category : Science
ISBN : 9783527667536

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Lithium Compounds in Organic Synthesis by Renzo Luisi,Vito Capriati Pdf

This unique book covers fundamentals of organolithium compounds and gives a comprehensive overview of the latest synthetic advances and developments in the field. Part I covers computational and spectroscopic aspects as well as structure-reactivity relationships of organolithiums, whereas Part II deals with new lithium-based synthetic methodologies as well as novel synthetic applications of functionalized lithium compounds. A useful resource for newcomers and active researchers involved in organic synthesis, whether working in academia or industry!

Author : Jonathan Clayden
Publisher : Elsevier
Page : 401 pages
File Size : 42,9 Mb
Release : 2002-07-12
Category : Science
ISBN : 9780080538167

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Organolithiums: Selectivity for Synthesis by Jonathan Clayden Pdf

This volume, number 23 in the "Tetrahedron Organic Chemistry" series, presents organolithium chemistry from the perspective of a synthetic organic chemist, drawing from the synthetic literature to present a unified overview of how organolithiums can be used to make molecules. The development of methods for the regioselective synthesis of organolithiums has replaced their image of indiscriminate high reactivity with one of controllable and subtle selectivity. Organolithium chemistry has a central role in the selective construction of C-C bonds in both simple and complex molecules, and for example has arguably overtaken aromatic electrophilic substitution as the most powerful method for regioselective functionalisation of aromatic rings. The twin themes of reactivity and selectivity run through the book, which reviews the ways by which organolithiums may be formed and the ways in which they react. Topics include advances in directed metallation, reductive lithiation and organolithium cyclisation reactions, along with a discussion of organolithium stereochemistry and the role played by ligands such as (-)-sparteine.

Author : Jacek Wojaczynski,Elzbieta Wojaczynska
Publisher : John Wiley & Sons
Page : 692 pages
File Size : 55,5 Mb
Release : 2022-08-05
Category : Science
ISBN : 9783527834198

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Chiral Building Blocks in Asymmetric Synthesis by Jacek Wojaczynski,Elzbieta Wojaczynska Pdf

Chiral Building Blocks in Asymmetric Synthesis A comprehensive introduction to the important classes of chiral building blocks Chirality — the asymmetric quality found in certain chemical compounds — plays an essential role in our world: chiral compounds can be found in biology, pharmaceutical compounds, agrochemicals, and fragrances. The stereoselective preparation of these complex molecular constructions constitutes a challenge. To this end, modern asymmetric synthesis utilizes a variety of valuable and efficient reagents employed as chiral auxiliaries, metal complexes and organocatalysts in stereoselective catalysis, and enantiopure reactants termed as chiral building blocks. In Chiral Building Blocks in Asymmetric Synthesis, the achievements in the fields of preparation of and applications of chiral blocks are presented. In doing so, the book comprehensively discusses the important classes of these reactants as the key for the asymmetric synthesis of chiral molecules. As such, it is an indispensable resource about synthetic methods, as well as possible modifications and transformations of important classes of chiral compounds. It also highlights the importance of their use as reactants and auxiliaries in the preparation of more sophisticated molecules or supramolecular systems. In Chiral Building Blocks in Asymmetric Synthesis readers will also find: Organization according to the most important compound classes — e.g. amino acids, BINOL and its derivatives, terpenes, and others — with an emphasis on synthesis and application A focus on the use of chiral building blocks for the preparation of bioactive compounds and supramolecular assemblies Chiral Building Blocks in Asymmetric Synthesis is a useful reference for organic chemists, catalytic chemists, chemists in industry, medicinal chemists, pharmaceutical chemists, and the libraries that support them.

Author : Anonim
Publisher : Newnes
Page : 9815 pages
File Size : 49,8 Mb
Release : 2014-02-14
Category : Science
ISBN : 9780080977430

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Comprehensive Organic Synthesis by Anonim Pdf

The second edition of Comprehensive Organic Synthesis—winner of the 2015 PROSE Award for Multivolume Reference/Science from the Association of American Publishers—builds upon the highly respected first edition in drawing together the new common themes that underlie the many disparate areas of organic chemistry. These themes support effective and efficient synthetic strategies, thus providing a comprehensive overview of this important discipline. Fully revised and updated, this new set forms an essential reference work for all those seeking information on the solution of synthetic problems, whether they are experienced practitioners or chemists whose major interests lie outside organic synthesis. In addition, synthetic chemists requiring the essential facts in new areas, as well as students completely new to the field, will find Comprehensive Organic Synthesis, Second Edition, Nine Volume Set an invaluable source, providing an authoritative overview of core concepts. Winner of the 2015 PROSE Award for Multivolume Reference/Science from the Association of American Publishers Contains more than170 articles across nine volumes, including detailed analysis of core topics such as bonds, oxidation, and reduction Includes more than10,000 schemes and images Fully revised and updated; important growth areas—including combinatorial chemistry, new technological, industrial, and green chemistry developments—are covered extensively

Author : Anonim
Publisher : Academic Press
Page : 324 pages
File Size : 43,8 Mb
Release : 2016-01-28
Category : Science
ISBN : 9780128048467

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Advances in Heterocyclic Chemistry by Anonim Pdf

Advances in Heterocyclic Chemistry is the definitive series in the field—one of great importance to organic chemists, polymer chemists, and many biological scientists. Because biology and organic chemistry increasingly intersect, the associated nomenclature also is being used more frequently in explanations. Written by established authorities in the field from around the world, this comprehensive review combines descriptive synthetic chemistry and mechanistic insight to yield an understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds. Considered the definitive serial in the field of heterocyclic chemistry Serves as the go-to reference for organic chemists, polymer chemists, and many biological scientists Provides the latest comprehensive reviews written by established authorities in the field Combines descriptive synthetic chemistry and mechanistic insight to enhance understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds

Author : Robert A. Moss,Michael P. Doyle
Publisher : John Wiley & Sons
Page : 506 pages
File Size : 43,5 Mb
Release : 2013-10-17
Category : Science
ISBN : 9781118730263

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Contemporary Carbene Chemistry by Robert A. Moss,Michael P. Doyle Pdf

Presents the most innovative results in carbene chemistry, setting the foundation for new discoveries and applications The discovery of stable carbenes has reinvigorated carbene chemistry research, with investigators seeking to develop carbenes into new useful catalysts and ligands. Presenting the most innovative and promising areas of carbene research over the past decade, this book explores newly discovered structural, catalytic, and organometallic aspects of carbene chemistry, with an emphasis on new and emerging synthetic applications. Contemporary Carbene Chemistry features contributions from an international team of pioneering carbene chemistry researchers. Collectively, these authors have highlighted the most interesting and promising areas of investigation in the field. The book is divided into two parts: Part 1, Properties and Reactions of Carbenes, explores new findings on carbene stability, acid-base behavior, and catalysis. Carbenic structure and reactivity are examined in chapters dedicated to stable carbenes, carbodicarbenes, carbenes as guests in supramolecular hosts, tunneling in carbene and oxacarbene reactions, and ultrafast kinetics of carbenes and their excited state precursors. Theoretical concerns are addressed in chapters on computational methods and dynamics applied to carbene reactions. Part 2, Metal Carbenes, is dedicated to the synthetic dimensions of carbenes, particularly the reactions and catalytic properties of metal carbenes. The authors discuss lithium, rhodium, ruthenium, chromium, molybdenum, tungsten, cobalt, and gold. All the chapters conclude with a summary of the current situation, new challenges on the horizon, and promising new research directions. A list of key reviews and suggestions for further reading also accompanies every chapter. Each volume of the Wiley Series on Reactive Intermediates in Chemistry and Biology focuses on a specific reactive intermediate, offering a broad range of perspectives from leading experts that sets the stage for new applications and further discoveries.

Author : Anonim
Publisher : John Wiley & Sons
Page : 1130 pages
File Size : 46,8 Mb
Release : 2019-12-05
Category : Science
ISBN : 9781119456667

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Organic Reactions, Volume 100 by Anonim Pdf

Written by a "who is who" of leading organic chemists, this anniversary volume represent the Organic Reactions editors' choice of the most important, ground-breaking and versatile reactions in current organic synthesis. The 15 reaction types selected for this volume include reactions for carbon-carbon bond formation, cross-coupling reactions, hydro- and halofunctionalizations, among many others. In line with the successful recipe of the series, each chapter is focused on a single reaction, discussing its mechanism and stereochemistry, scope and limitations, applications to synthesis, comparison with other methods, and experimental procedures. Each chapter concludes with a tabular survey of selected key application examples, complete with reported reaction conditions and yields, to serve as a quick reference guide for synthesis planning.

Author : Jacques Mortier
Publisher : John Wiley & Sons
Page : 992 pages
File Size : 44,9 Mb
Release : 2015-11-30
Category : Science
ISBN : 9781118754955

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Arene Chemistry by Jacques Mortier Pdf

Organized to enable students and synthetic chemists to understand and expand on aromatic reactions covered in foundation courses, the book offers a thorough and accessible mechanistic explanation of aromatic reactions involving arene compounds. • Surveys methods used for preparing arene compounds and their transformations • Connects reactivity and methodology with mechanism • Helps readers apply aromatic reactions in a practical context by designing syntheses • Provides essential information about techniques used to determine reaction mechanisms

Author : Zvi Rappoport
Publisher : Unknown
Page : 717 pages
File Size : 50,9 Mb
Release : 2004
Category : Electronic
ISBN : OCLC:634928106

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The Chemistry of Organolithium Compounds by Zvi Rappoport Pdf

Author : Robert E. Gawley,Jeffrey Aube
Publisher : Elsevier
Page : 569 pages
File Size : 43,5 Mb
Release : 2012-07-16
Category : Science
ISBN : 9780080448602

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Principles of Asymmetric Synthesis by Robert E. Gawley,Jeffrey Aube Pdf

The world is chiral. Most of the molecules in it are chiral, and asymmetric synthesis is an important means by which enantiopure chiral molecules may be obtained for study and sale. The aim of this book is to present a detailed analysis of the factors that govern stereoselectivity in organic reactions.