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Structure And Function Of The Neural Cell Adhesion Molecule Ncam Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Structure And Function Of The Neural Cell Adhesion Molecule Ncam book. This book definitely worth reading, it is an incredibly well-written.
Author : Vladimir Berezin
Publisher : Springer Science & Business Media
Page : 429 pages
File Size : 42,9 Mb
Release : 2009-12-17
Category : Medical
ISBN : 9781441911704
This book describes recent developments concerning structural, functional and possible therapeutic aspects of one particular CAM, the neural cell adhesion molecule (NCAM).
Author : Anonim
Publisher : ScholarlyEditions
Page : 46 pages
File Size : 45,8 Mb
Release : 2012-12-26
Category : Medical
ISBN : 9781481624503
Neuronal Cell Adhesion Molecules—Advances in Research and Application: 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Neuronal Cell Adhesion Molecules in a compact format. The editors have built Neuronal Cell Adhesion Molecules—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Neuronal Cell Adhesion Molecules in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Neuronal Cell Adhesion Molecules—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author : Anonim
Publisher : ScholarlyEditions
Page : 25 pages
File Size : 49,7 Mb
Release : 2012-01-09
Category : Medical
ISBN : 9781464954313
Neuronal Cell Adhesion Molecules: Advances in Research and Application: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Neuronal Cell Adhesion Molecules in a compact format. The editors have built Neuronal Cell Adhesion Molecules: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Neuronal Cell Adhesion Molecules in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Neuronal Cell Adhesion Molecules: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author : Jan Pruszak
Publisher : Academic Press
Page : 254 pages
File Size : 47,8 Mb
Release : 2015-03-23
Category : Science
ISBN : 9780128011263
Neural Surface Antigens: From Basic Biology towards Biomedical Applications focuses on the functional role of surface molecules in neural development, stem cell research, and translational biomedical paradigms. With an emphasis on human and rodent model systems, this reference covers fundamentals of neural stem cell biology and flow cytometric methodology. Addressing cell biologists as well as clinicians working in the neurosciences, the book was conceived by an international panel of experts to cover a vast array of particular surface antigen families and subtypes. It provides insight into the basic biology and functional mechanisms of neural cell surface signaling molecules influencing mammalian development, regeneration, and treatments. Introduces early phase clinical trials of neural stem cells Outlines characterization of surface molecule expression and methods for isolation which open unprecedented opportunities for functional study, quantitation & diagnostics Highlights the role of stem cells in neural surface antigen and biomarker analysis and applications
Author : Ajit Varki,Maarten J. Chrispeels
Publisher : CSHL Press
Page : 694 pages
File Size : 45,9 Mb
Release : 1999
Category : Medical
ISBN : 0879696818
Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
Author : Anonim
Publisher : Elsevier
Page : 506 pages
File Size : 50,7 Mb
Release : 2014-10-30
Category : Science
ISBN : 9780444634948
In the central nervous system, extracellular matrix (ECM) molecules, including hyaluronic acid, chondroitin and heparan sulfate proteoglycans, tenascins, reelin and agrin, along with their remodelling enzymes, such as neurotrypsin, neuropsin, plasminogen activators, and metalloproteinases, are secreted by neural and non-neural cells into the extracellular space to form the ECM and signal via ECM receptors. Despite recent advances in the ECM field, the importance of neural ECM for physiological and pathological processes is currently less widely recognized than that of other CNS elements. This book will enlighten recent progress in our understanding of mechanisms by which neural ECM, its receptors and activity-dependent ECM remodeling regulate neural development, synaptic plasticity, and contribute to pathological changes in the brain. In the first part, the roles of ECM signaling and proteolytic modification of ECM in neurogenesis, neural migration, axonal pathfinding, synaptogenesis, synaptic and homeostatic plasticity will be discussed. The second part will focus on the emerging ECM-dependent mechanisms associated with CNS injury, epilepsy, neurodegenerative and neuropsychiatric diseases. For further development of neural ECM field, a very important contribution is the third part of the book, which is devoted to neural ECM-targeting tools and therapeutics. The concluding fourth part will highlight advances in development of artificial ECM and ECM-based systems suitable for multisite recording and stimulation of neural cells. Authors are the leading experts in the field of brain extracellular matrix in health and disease Book covers the most important aspects of brain extracellular matrix in health and disease Interesting for both scientists and clinicians
Author : Michael E. Selzer,Stephanie Clarke,Leonardo G. Cohen,Gert Kwakkel (Professor),Robert H. Miller (Professor)
Publisher : Cambridge University Press
Page : 693 pages
File Size : 54,7 Mb
Release : 2014
Category : Nervous system
ISBN : 9781107011670
In two freestanding volumes, the Textbook of Neural Repair and Rehabilitation provides comprehensive coverage of the science and practice of neurological rehabilitation. Revised throughout, bringing the book fully up to date, this volume, Neural Repair and Plasticity, covers the basic sciences relevant to recovery of function following injury to the nervous system, reviewing anatomical and physiological plasticity in the normal central nervous system, mechanisms of neuronal death, axonal regeneration, stem cell biology, and research strategies targeted at axon regeneration and neuron replacement. New chapters have been added covering pathophysiology and plasticity in cerebral palsy, stem cell therapies for brain disorders and neurotrophin repair of spinal cord damage, along with numerous others. Edited and written by leading international authorities, it is an essential resource for neuroscientists and provides a foundation for the work of clinical rehabilitation professionals.
Author : Gerd Kempermann
Publisher : Oxford University Press, USA
Page : 464 pages
File Size : 51,6 Mb
Release : 2006
Category : Adulthood
ISBN : 0195179714
The discovery of adult neurogenesis and of stem cells in the brain has changed our view of the mature brain. Though we now know that the adult brain can make new neurons, it normally does so only in two privileged regions, the olfactory bulb and the hippocampus. Yet stem cells, which have the potential to produce new neurons, can be found throughout the adult brain. So why does the brain not make wider use of its potential for neurogenesis? And what is the function of new neurons and of neural stem cells in areas where they occur? After all, the brain regenerates poorly and many neurological and psychiatric disorders are chronic because cell replacement has not taken place. This is the first comprehensive, integrated account of one of the most exciting areas of neuroscience. It begins with the historical background and discusses theories of adult neurogenesis and neural stem cell biology in the context of learning and memory processes as well as structural plasticity. It describes in detail neurogenesis in the adult hippocampus and olfactory system and then surveys the regulatory, functional, and comparative aspects, concluding with a chapter on the provocative hypotheses that link failing adult neurogenesis with such diseases as temporal lobe epilepsy, major depression, brain tumors, and dementias. For graduate students, investigators, and clinicians in the neurosciences, developmental biology, and stem cell research, this book is a unique resource that sifts through the evidence for exciting scientific ideas and fosters a realistic view of the therapeutic possibilities for the use of stem cells in the adult brain.
Author : Peter Sonderegger
Publisher : CRC Press
Page : 326 pages
File Size : 49,9 Mb
Release : 2003-09-02
Category : Science
ISBN : 9780203303696
A vast number of neural cell surface glycoproteins belonging to the immunoglobulin superfamily have been isolated over the past two decades. In functional studies, many of them have been shown to confer adhesive properties to cells and to play an important role in developmental processes such as cell migration and axon outgrowth. Recent observations implicate Ig superfamily adhesion molecules in the regulation of activity-dependent synaptic plasticity, in regeneration after neural trauma, as well as in the pathogenesis of malformations in the developing nervous systems. This book summarizes the molecular features and some of the cellular functions of this important class of cell surface molecules. It includes detailed information on the molecular structure of the immunoglobulin fold, the common domain of these proteins, the molecular interactions between various neural Ig superfamily members and their role in signal transduction, as well as the role of Ig superfamily adhesion molecules in axon guidance during both vertebrate and invertebrate neurogenesis. Recent observations on a role for these molecules in activity-dependent synaptic plasticity and in the regeneration of injured axons in the peripheral and central nervous system are described. A discussion on the connection between Ig superfamily adhesion molecules and medical genetics is also provided.
Author : Abel Lajtha,Regino Perez-Polo,Steffen Roßner
Publisher : Springer Science & Business Media
Page : 332 pages
File Size : 50,9 Mb
Release : 2008-06-06
Category : Medical
ISBN : 9780387326702
The nervous system is highly fragile, especially during aging, illness and trauma. This book addresses a small sampling of major constituents of neural function at the cellular and molecular level that play crucial roles in development and aging.
Author : W.R. Ferrell,Uwe Proske
Publisher : Springer Science & Business Media
Page : 295 pages
File Size : 43,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461519850
Presented with a choice of evils, most would prefer to be blinded rather than to be unable to move, immobilized in the late stages of Parkinson's disease. Yet in everyday life, as in Neuroscience, vision holds the centre of the stage. The conscious psyche watches a private TV show all day long, while the motor system is left to get on with it "out of sight and out of mind. " Motor skills are worshipped at all levels of society, whether in golf, tennis, soccer, athletics or in musical performance; meanwhile the subconscious machinery is ignored. But scientifically there is steady advance on a wide front, as we are reminded here, from the reversal of the reflexes of the stick insects to the site of motor learning in the human cerebral cortex. As in the rest of Physiology, evolution has preserved that which has already worked well; thus general principles can often be best discerned in lower animals. No one scientist can be personally involved at all levels of analysis, but especially for the motor system a narrow view is doomed from the outset. Interaction is all; the spinal cord has surrendered its autonomy to the brain, but the brain can only control the limbs by talking to the spinal cord in a language that it can understand, determined by its pre-existing circuitry; and both receive a continuous stream of feedback from the periphery.
Author : Federico Bermudez-Rattoni
Publisher : CRC Press
Page : 368 pages
File Size : 52,5 Mb
Release : 2007-04-17
Category : Psychology
ISBN : 9781420008418
A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniq
Author : Manfred Gratzl,Keith Langley
Publisher : Unknown
Page : 248 pages
File Size : 50,9 Mb
Release : 1991
Category : Biochemical markers
ISBN : UCAL:B4524739
Author : Michael Hortsch,Hisashi Umemori
Publisher : Springer Science & Business Media
Page : 451 pages
File Size : 46,6 Mb
Release : 2009-06-07
Category : Medical
ISBN : 9780387927084
The molecular mechanisms, which are responsible for the functional differences between the various types of neuronal synapses, have become one of the central themes of modern neurobiology. It is becoming increasingly clear that a misregulation of synaptogenesis and synaptic remodeling and dysfunctional neuronal synapses are at the heart of several human diseases, both neurological disorders and psychiatric conditions. As synapses present specialized cellular junctions between neurons and their target cells, it may not come as a surprise that neural cell adhesion molecules (CAMs) are of special importance for the genesis and the maintenance of synaptic connections. Genes encoding adhesive molecules make up a significant portion of the human genome, and neural CAMs even have been postulated to be a major factor in the evolution of the human brain. These are just some of the many reasons why we thought a book on neural CAMs and their role in establishing and maintaining neuronal synapses would be highly appropriate for summarizing our current state of knowledge. Without question, over the near future, additional adhesive proteins will join the ranks of synaptic CAMs and our knowledge, and how these molecules enable neurons and their targets to communicate effectively will grow.
Author : Anonim
Publisher : Elsevier
Page : 336 pages
File Size : 41,7 Mb
Release : 2000-08-24
Category : Science
ISBN : 0080525970
This updated and expanded Second Edition of The Adhesion Molecule FactsBook has nearly double the number of entries of the First Edition, and provides a compendium of the major cell surface adhesion molecules. The introductory chapters detail the organization of the data in the entries section, provide a background to the main adhesion molecule families, and inform the reader how to access information on adhesion molecules on the Internet. The entries have been designed to allow the reader to quickly establish the main structure and functional features of each molecule and where to find information. alternative nomenclature tissue distribution and regulation of expression ligands gene organization and chromosomal location protein structure and molecular weights amino acid sequence of the most commonly studied organisms PIR, SWISSPROT, and EMBL/GenBank accession numbers biological function key references
