Surface Characterization Of Biomaterials

Author : Amit Bandyopadhyay,Susmita Bose
Publisher : Newnes
Page : 450 pages
File Size : 45,7 Mb
Release : 2013-03-12
Category : Technology & Engineering
ISBN : 9780124158634

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Characterization of Biomaterials by Amit Bandyopadhyay,Susmita Bose Pdf

One of the key challenges current biomaterials researchers face is identifying which of the dizzying number of highly specialized characterization tools can be gainfully applied to different materials and biomedical devices. Since this diverse marketplace of tools and techniques can be used for numerous applications, choosing the proper characterization tool is highly important, saving both time and resources. Characterization of Biomaterials is a detailed and multidisciplinary discussion of the physical, chemical, mechanical, surface, in vitro and in vivo characterization tools and techniques of increasing importance to fundamental biomaterials research. Characterization of Biomaterials will serve as a comprehensive resource for biomaterials researchers requiring detailed information on physical, chemical, mechanical, surface, and in vitro or in vivo characterization. The book is designed for materials scientists, bioengineers, biologists, clinicians and biomedical device researchers seeking input on planning on how to test their novel materials, structures or biomedical devices to a specific application. Chapters are developed considering the need for industrial researchers as well as academics. Biomaterials researchers come from a wide variety of disciplines: this book will help them to analyze their materials and devices taking advantage of the multiple experiences on offer. Coverage encompasses a cross-section of the physical sciences, biological sciences, engineering and applied sciences characterization community, providing gainful and cross-cutting insight into this highly multi-disciplinary field. Detailed coverage of important test protocols presents specific examples and standards for applied characterization

Author : T.S. Sampath Kumar
Publisher : Elsevier Inc. Chapters
Page : 450 pages
File Size : 46,8 Mb
Release : 2013-03-12
Category : Science
ISBN : 9780128070963

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Characterization of Biomaterials by T.S. Sampath Kumar Pdf

The physicochemical properties of biomaterials exert a major influence over their interaction with cells and subsequently play an important role on the materials' in vivo performance . Physical characteristics involve internal microstructural features, shape and size of particles, porosity, density, and surface area. Characterization in terms of the chemistry involves determination of the chemical composition and distribution of the elements within the biomaterial. The last decade has seen several innovations in the armory of tools to image and analyze materials, as well as advancement in the collection and processing of those results. In this chapter, the most commonly used methods, which are available for the microstructural characterization of biomaterials, are explained with suitable examples. This chapter starts with microstructural characterization using different types of microscopic techniques including optical and electron microscopy. These techniques can provide information from atomic-scale to microscale to macroscale information. Specific examples are also used for specialized microscopic techniques such as scanning probe microscopy and atomic force microscopy. Some discussions were also used in -related surface characterization using microscopic techniques. Followed by microscopic techniques, phase analysis techniques are discussed based on X-ray diffraction. Short discussion is also placed on infrared (IR)-based spectroscopic characterization for chemical analysis. Further discussion on IR spectroscopy can be found in for surface analysis. The last part of this chapter deals with size, shape, porosity, surface area and surface energy characterization. Particle size analysis by dynamic light scattering (DLS) is discussed in detail followed by IR spectroscopic analysis. Contact angle measurement for surface energy, mercury intrusion porosimetry for analysis of pore structures and gas adsorption measurements for surface area analysis are presented in detail with relevant examples. Throughout this chapter, specific discussions are focused on examples based on applications as well as advantages, disadvantages, and challenges.

Author : Huaiyu Wang,Paul K. Chu
Publisher : Elsevier Inc. Chapters
Page : 450 pages
File Size : 51,7 Mb
Release : 2013-03-12
Category : Science
ISBN : 9780128070987

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Characterization of Biomaterials by Huaiyu Wang,Paul K. Chu Pdf

The biomaterials surface, which may only be a few atomic layers thick, constitutes the important interface between the biomaterials and the external biological environment and plays a key role in the chemical and biological actions in vitro and in vivo. Hence, in order to monitor and fathom the biological performance of biomaterials, the surface properties must be well known. Recently, surface modification of biomaterials has attracted considerable attention as selective surface properties such as cytocompatibility can be altered while desirable bulk properties such as mechanical strength can be retained. In this respect, surface characterization techniques are indispensable in this important and burgeoning research area. No single technique can provide all the information, and quite often, different analytical tools are required to address a problem related to biomaterials research. To obtain surface chemical and morphological information, spectroscopic techniques such as X-ray photoelectron spectroscopy (XPS), Auger electron spectroscopy (AES), secondary ion mass spectroscopy (SIMS), and microscopic methods such as confocal microscopy, scanning electron microscopy, atomic force microscopy (AFM) are typically carried out. Other surface characterization methods such as contact angle (CA) measurement and ellipsometry are also widely used in biomaterials research. It should be emphasized that each technique has its strengths and weaknesses, and complete characterization frequently requires more than one method. In this chapter, we introduce and describe some of the common surface characterization techniques suitable for biomaterials. Initial discussion starts with spectroscopic techniques, their operation principles, and data analysis with specific examples. The discussions related to spectroscopic characterization are focused on XPS, AES, SIMS, surface matrix-assisted laser desorption ionization mass spectrometry (Surface-MALDI-MS), infrared spectroscopy, Raman spectroscopy, electron energy loss spectroscopy and ultraviolet spectroscopy. After spectroscopic characterization techniques, this chapter focuses on microscopic characterization. This part of the chapter is specifically focused on optical, electron and confocal microscopic techniques. Microscopic technique also discusses recent advances in atomic level characterization using scanning tunnelling microscopy and AFM. Finally, the chapter deals with specific surface characterization techniques for morphology with profilometry followed by surface charge measurement using CAs. The last section of the chapter deals with ellipsometry, a specular optical technique which provides unequalled capabilities for thin film metrology. Throughout this chapter, specific discussions are focused on examples based on applications as well as advantages, disadvantages, and challenges.

Author : Buddy D. Ratner
Publisher : Elsevier Science Limited
Page : 334 pages
File Size : 40,8 Mb
Release : 1988-01-01
Category : Medical
ISBN : 0444430164

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Surface Characterization of Biomaterials by Buddy D. Ratner Pdf

Surface Characterization of Biomaterials is the first book to define the scope of contemporary research in this area by presenting articles from almost all the groups worldwide who are utilizing both new and traditional methods to explore the surfaces of biomaterials. The book contains introductory, tutorial articles on important methods, perspective articles clarifying why these methods are important to biomaterials science, and sixteen research articles illustrating how these tools are being used by most of the leaders in this field. The techniques featured include ESCA, static SIMS, contact angle methods, scanning electron stimulated desorption microscopy, Fourier transform infrared methods, and transmission electron microscopy. The classes of materials described include polymers, ceramics and metals. Surface modification of many of these materials is discussed. The biological problems addressed include blood compatibility, cell adhesion, osteointegration, and protein adsorption. The book will be welcomed by researchers and manufacturers interested in biomaterials. Experts in the field will find an overview of contemporary research.

Author : Maria Cristina Tanzi,Silvia Farè
Publisher : Woodhead Publishing
Page : 503 pages
File Size : 50,9 Mb
Release : 2017-06-20
Category : Technology & Engineering
ISBN : 9780081007433

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Characterization of Polymeric Biomaterials by Maria Cristina Tanzi,Silvia Farè Pdf

Characterization of Polymeric Biomaterials presents a comprehensive introduction on the topic before discussing the morphology and surface characterization of biomedical polymers. The structural, mechanical, and biological characterization is described in detail, followed by invaluable case studies of polymer biomaterial implants. With comprehensive coverage of both theoretical and experimental information, this title will provide scientists with an essential guide on the topic of these materials which are regularly used for clinical applications, such as implants and drug delivery devices. However, a range of novel polymers and the development and modification of existing medical polymers means that there is an ongoing need to satisfy particular design requirements. This book explains the critical and fundamentals methods to characterize polymer materials for biomedical applications. Presents a self-contained reference on the characterization of polymeric biomaterials Provides comprehensive information on how to characterize biomedical polymers in order to improve design and synthesis Includes useful case studies that demonstrate the characterization of biomaterial implants

Author : National Heart, Lung, and Blood Institute,National Heart, Lung, and Blood Institute. Working Group on Physicochemical Characterization of Biomaterials
Publisher : Unknown
Page : 140 pages
File Size : 46,7 Mb
Release : 1980
Category : Biomedical materials
ISBN : UOM:39015069165580

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Guidelines for Physicochemical Characterization of Biomaterials, April 1979 by National Heart, Lung, and Blood Institute,National Heart, Lung, and Blood Institute. Working Group on Physicochemical Characterization of Biomaterials Pdf

Author : Cuie Wen
Publisher : Woodhead Publishing
Page : 464 pages
File Size : 50,7 Mb
Release : 2021-04-06
Category : Technology & Engineering
ISBN : 9780128188323

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Structural Biomaterials by Cuie Wen Pdf

Structural Biomaterials: Properties, Characteristics, and Selection serves as a single point of reference to digest current research and develop a deeper understanding in the field of biomaterials engineering. This book uses a materials-focused approach, allowing the reader to quickly access specific, detailed information on biomaterials characterization and selection. Relevant to a range of readers, this book provides holistic coverage of the broad categories of structural biomaterials currently available and used in medical applications, highlighting the property requirements for structural biomaterials, their biocompatibility performance and their safety regulation in key categories such as metals, ceramics and polymers. The materials science perspective of this text ensures the content is accessible even to those without an extensive background in applied medicine, positioning this text not just for students, but as an overview and reference for researchers, scientists and engineers entering the field from related materials science disciplines. Provides a unique, holistic approach, covering key biomaterials categories in one text, including metals, ceramics and polymers Discusses advantages, disadvantages, biocompatibility performance and safety regulations, allowing for accurate materials selection in medical applications Utilizes a materials science perspective, allowing those without an extensive applied medical background to learn about the field

Author : Lia Rimondini,Claudia L. Bianchi,Enrica Vernè
Publisher : Bentham Science Publishers
Page : 422 pages
File Size : 41,9 Mb
Release : 2012-10-18
Category : Technology & Engineering
ISBN : 9781608054626

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Surface Tailoring of Inorganic Materials for Biomedical Applications by Lia Rimondini,Claudia L. Bianchi,Enrica Vernè Pdf

Inorganic materials have been used for biomedical applications since many decades. They have been utilized successfully because of easy and economic methods for bulk preparation and industrial manufacturing. Surface modifications significantly improve the success of these materials and enable us to exploit their application in many innovative fields such as tissue engineering, dentistry, nanocarriers for drugs, medical diagnosis and antifouling technologies. This e-book provides comprehensive information on technologies for development and characterization of successful functionalized materials for biomedical applications relevant to surface modification. It is a suitable reference for advanced students and researchers interested in biomaterials science and medical applications of inorganic substances.

Author : J. L. Ong,Mark R. Appleford,Gopinath Mani
Publisher : Cambridge University Press
Page : 421 pages
File Size : 53,6 Mb
Release : 2014
Category : Medical
ISBN : 9780521116909

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Introduction to Biomaterials by J. L. Ong,Mark R. Appleford,Gopinath Mani Pdf

A succinct introduction to the field of biomaterials engineering, packed with practical insights.

Author : Andreas Taubert,Joao F. Mano,Jos¿ Carlos Rodr¿guez-Cabello
Publisher : John Wiley & Sons
Page : 599 pages
File Size : 45,5 Mb
Release : 2013-07-23
Category : Science
ISBN : 9783527649624

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Biomaterials Surface Science by Andreas Taubert,Joao F. Mano,Jos¿ Carlos Rodr¿guez-Cabello Pdf

At the interface of biology, chemistry, and materials science, this book provides an overview of this vibrant research field, treating the seemingly distinct disciplines in a unified way by adopting the common viewpoint of surface science. The editors, themselves prolific researchers, have assembled here a team of top-notch international scientists who read like a "who's who" of biomaterials science and engineering. They cover topics ranging from micro- and nanostructuring for imparting functionality in a top-down manner to the bottom-up fabrication of gradient surfaces by self-assembly, from interfaces between biomaterials and living matter to smart, stimuli-responsive surfaces, and from cell and surface mechanics to the elucidation of cell-chip interactions in biomedical devices. As a result, the book explains the complex interplay of cell behavior and the physics and materials science of artificial devices. Of equal interest to young, ambitious scientists as well as to experienced researchers.

Author : Buddy D. Ratner,David G. Castner
Publisher : Springer Science & Business Media
Page : 200 pages
File Size : 40,9 Mb
Release : 2013-06-29
Category : Science
ISBN : 9781489919533

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Surface Modification of Polymeric Biomaterials by Buddy D. Ratner,David G. Castner Pdf

Applications of synthetic materials in medicine date back over 4000 year2. The Egyptians used linen as sutures. In the Roman Empire, gold was used in dentistry. Perhaps even earlier, ivory and bone may have been used in the body by practitioners of the healing arts. The historical origins of modem biomaterials science are also hard to precisely trace, but many of the ideas that define biomaterials as we know them today evolved in the late 1950s and early 1960s. Surface modification technology has played a prominent role in biomaterials science, and has paralleled the evolution of the modem field. In a symposium organized by the Artifical Heart Program of the NIH National Heart Institute and the Artificial Kidney program of the NIH National Institute of Arthritis and Metabolic Diseases, held in Atlantic City, New Jersey, in 1968, there were already a number of presentations on surface modification. Surface characterization at that time included scanning electron microscopy, ellipsometry, contact angle methods, and infrared internal reflection methods.

Author : Rachel Williams
Publisher : Elsevier
Page : 438 pages
File Size : 49,7 Mb
Release : 2010-11-25
Category : Medical
ISBN : 9780857090768

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Surface Modification of Biomaterials by Rachel Williams Pdf

The surface modification of biomaterials plays a significant role in determining the outcome of biological-material interactions. With the appropriate modification a material’s surface can be tailored to improve biocompatibility, adhesion and cell interactions. Consequently surface modification is vital in the development and design of new biomaterials and medical devices. Surface modification of biomaterials reviews both established surface modifications and those still in the early stages of research and discusses how they can be used to optimise biological interactions and enhance clinical performance.Part one begins with chapters looking at various types and techniques of surface modification including plasma polymerisation, covalent binding of poly (ethylene glycol) (PEG), heparinisation, peptide functionalisation and calcium phosphate deposition before going on to examine metal surface oxidation and biomaterial surface topography to control cellular response with particular reference to technologies, cell behaviour and biomedical applications. Part two studies the analytical techniques and applications of surface modification with chapters on analysing biomaterial surface chemistry, surface structure, morphology and topography before moving onto discuss modifying biomaterial surfaces to optimise interactions with blood, control infection, optimise interactions with soft tissues, repair and regenerate nerve cells, control stem cell growth and differentiation and to optimise interactions with bone.The distinguished editor and international team of contributors to Surface modification of biomaterials have produced a unique overview and detailed chapters on a range of surface modification techniques which will provide an excellent resource for biomaterials researchers and scientists and engineers concerned with improving the properties of biomaterials. It will also be beneficial for academics researching surface modification. Reviews both established surface modifications and those still in the early stages of research and how they can be used to optimise biological interactions and enhance clinical performance Studies analytical techniques and applications of surface modification with chapters assessing biomaterial surface chemistry, surface structure, morphology and topography Discusses modifying biomaterial surfaces to optimise interactions with blood and soft tissues and also to repair and regenerate nerve cells and control infection

Author : Yaser Dahman
Publisher : CRC Press
Page : 358 pages
File Size : 43,5 Mb
Release : 2019-02-11
Category : Medical
ISBN : 9780429878350

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Biomaterials Science and Technology by Yaser Dahman Pdf

Biomaterials Science and Technology: Fundamentals and Developments presents a broad scope of the field of biomaterials science and technology, focusing on theory, advances, and applications. It reviews the fabrication and properties of different classes of biomaterials such as bioinert, bioactive, and bioresorbable, in addition to biocompatibility. It further details traditional and recent techniques and methods that are utilized to characterize major properties of biomaterials. The book also discusses modifications of biomaterials in order to tailor properties and thus accommodate different applications in the biomedical engineering fields and summarizes nanotechnology approaches to biomaterials. This book targets students in advanced undergraduate and graduate levels in majors related to fields of Chemical Engineering, Materials Engineering and Science, Biomedical Engineering, Bioengineering, and Life Sciences. It assists in understanding major concepts of fabrication, modification, and possible applications of different classes of biomaterials. It is also intended for professionals who are interested in recent advances in the emerging field of biomaterials.

Author : Cuie Wen
Publisher : Woodhead Publishing
Page : 449 pages
File Size : 47,7 Mb
Release : 2015-03-31
Category : Technology & Engineering
ISBN : 9781782423164

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Surface Coating and Modification of Metallic Biomaterials by Cuie Wen Pdf

Despite advances in alternative materials, metals are still the biomaterial of choice for a number of clinical applications such as dental, orthopedic and cardiac implants. However, there are a number of intrinsic problems associated with implanting metal in the biological environment, such as wear, corrosion, biocompatibility and toxicity, which must be addressed. Modern technology has enabled scientists to modify metal surfaces or apply special coatings to metals to improve their performance safety. Surface Coating and Modification of Metallic Biomaterials will discuss the most important modification techniques and coatings for metals, first covering the fundamentals of metals as a biomaterial and then exploring surface modification techniques and coatings. An expansive overview of surface modification techniques for biomedical use In-depth exploration of issues arising from metal biomaterial use Includes examples of applications in a clinical setting

Author : Manfred Stamm
Publisher : Springer Science & Business Media
Page : 337 pages
File Size : 46,5 Mb
Release : 2008-01-26
Category : Technology & Engineering
ISBN : 9783540738657

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Polymer Surfaces and Interfaces by Manfred Stamm Pdf

In what is an extremely practical and applicable new work, experts provide concise explanations, with examples and illustrations, of the key techniques in this important field. In each case, after basic principles have been reviewed, applications of the experimental techniques are discussed and illustrated with specific examples. Scientists and engineers in research and development will benefit from an application-oriented book that helps them to find solutions to both fundamental and applied problems. They will know that the surfaces and interfaces of polymers play an important role in most of the application areas of polymers, from moulds, foils, and composites, to biomaterials and applications in micro- and nanotechnology.