Survival November 2023

Author : The International Institute for Strategic Studies (IISS)
Publisher : Taylor & Francis
Page : 184 pages
File Size : 51,7 Mb
Release : 2023-10-13
Category : History
ISBN : 9781003862697

Get Book

Survival: October – November 2023 by The International Institute for Strategic Studies (IISS) Pdf

Survival, the IISS’s bimonthly journal, challenges conventional wisdom and brings fresh, often controversial, perspectives on strategic issues of the moment. In this issue: Nick Childs assesses the ambitions and perils of the AUKUS partnership for Australia, the United Kingdom and the United States Kimberly Marten explores how the demise of its key figures will affect future operations of the Wagner Group and similar Russian paramilitaries Steven Feldstein investigates the uses and risks of generative-AI systems From the Survival archives, the late Pierre Hassner interpreted Russia’s August 2008 attack on Georgia as signalling the emergence of a new cold war with the West Dana H. Allin reflects on the European vision advanced by members of a rapidly disappearing generation of scholars who had lived through war and sought to preserve and extend peace And eight more thought-provoking pieces, as well as our regular Book Reviews and Noteworthy column. Editor: Dr Dana Allin Managing Editor: Jonathan Stevenson Associate Editor: Carolyn West Editorial Assistant: Conor Hodges

Author : Sheng Zhong,Peichen Pan,Ye Cheng,Wei Wang
Publisher : Frontiers Media SA
Page : 174 pages
File Size : 52,7 Mb
Release : 2024-03-26
Category : Science
ISBN : 9782832546178

Get Book

Advances in CNS Tumors Treatment and Diagnosis: Obstacles, Challenges, and Opportunities by Sheng Zhong,Peichen Pan,Ye Cheng,Wei Wang Pdf

Central nervous system (CNS) tumors are the eighth leading cause of cancer death and the second most common childhood cancer worldwide. Current treatment methods include surgery, radiation therapy, chemotherapy, targeted therapy, immune therapy etc. However, patients with CNS tumors usually have an unsatisfactory prognosis accompanied by impaired neurologic functions when compared with other cancers. Few drugs or treatments have been proven effective in CNS tumors due to the presence of blood-brain barriers and its distinctive tumor microenvironment.

Author : Zaheer-Ud-Din Babar,Dalia M. Dawoud,Blythe Adamson,Amr Makady,Grammati Sarri
Publisher : Frontiers Media SA
Page : 150 pages
File Size : 41,8 Mb
Release : 2024-04-10
Category : Science
ISBN : 9782832547649

Get Book

Novel methods and technologies for the evaluation of drug outcomes and policies by Zaheer-Ud-Din Babar,Dalia M. Dawoud,Blythe Adamson,Amr Makady,Grammati Sarri Pdf

As a leading Open Access publisher, Frontiers is committed to empowering not only scientists, but other researchers, innovators and members of the public. As such, highlighting sustainable development and the real-world applications of Drugs Outcomes Research & Policies are a key part to the agenda of Frontiers in Pharmacology. This Research Topic aims to highlight advancements in Health Economics and Outcomes Research (HEOR) techniques, methods and tools used by the pharmaceutical industry and other non-academic bodies.

Author : Patrick J. Ring,Jonquil Lowe,Lien Luu
Publisher : Taylor & Francis
Page : 174 pages
File Size : 45,7 Mb
Release : 2024-03-25
Category : Business & Economics
ISBN : 9781040004562

Get Book

Global Pension Challenges by Patrick J. Ring,Jonquil Lowe,Lien Luu Pdf

National pension systems face a range of tough social and economic demands and pressures. These are complex to navigate, especially in a twenty-first century world that has ushered in global uncertainty and pressing challenges - even threatening the planet’s very sustainability – with implications for pensions that policymakers, financial services providers and individuals themselves must address. This book probes, and unpacks, what pension systems aim to achieve, the uncertainties they face and how they are attempting to resolve them. Analysing pension provision from the systemic, political-economy and individual perspectives, it sets out and contextualises commonalities and differences in pension systems across the globe, looking at current developments in both public and private pension provision, structures and regulation. Moreover, the reader is encouraged to question how national pension systems can best serve their populations and ensure the ‘sustainability’ of later-life incomes in the light of today’s global pension challenges. Global Pension Challenges: Pensions, Saving and Retirement in the Twenty‐First Century is an essential read for business, finance and social-policy academics and students, those working in the pensions industry and in the areas of welfare reform and advocacy, as well as the general public wishing to know more about the retirement issues we will all face in the coming years.

Author : Anonim
Publisher : Frontiers Media SA
Page : 121 pages
File Size : 40,8 Mb
Release : 2024-02-28
Category : Medical
ISBN : 9782832545409

Get Book

Diagnosis, Epidemiology and Treatment of Salivary Gland Carcinomas by Anonim Pdf

Salivary gland carcinomas (SGCs) are a heterogeneous group of rare head and neck cancers made of more than 20 pathologic types. Although the treatments of the early or loco-regionally advanced disease are similar across the different entities, these malignancies have variable biological characteristics and clinical behaviors. These specificities, especially the pathologic type and, when available, the molecular profile, are taken into account while choosing the treatment for the recurrent/metastatic phase. In this context, only few druggable molecular targets have been tested so far and not all are available in clinical practice. However, due to the rarity of SGCs, clinical trials are challenging to conduct, and most of the available evidence comes from retrospective studies.

Author : Zheng Wang,Yanfeng Liu,Hangcheng Fu,Yonglong Zhang
Publisher : Frontiers Media SA
Page : 132 pages
File Size : 42,6 Mb
Release : 2024-02-22
Category : Medical
ISBN : 9782832545065

Get Book

Novel molecular mechanisms and clinical strategies in solid tumor recurrence and metastasis: from bench to bedside by Zheng Wang,Yanfeng Liu,Hangcheng Fu,Yonglong Zhang Pdf

Recurrence and metastasis of malignancy is a multistep process that involves the escape of tumor cells from the primary location, systemic translocation in the body, and adaptation to the foreign microenvironment of distant sites. The spread of cancer cells is mediated by the interaction between tumor cells (seeds) and the microenvironment of the host organ (soil). Emerging evidence has revealed several stages of the invasion-metastasis cascade, including epithelial-mesenchymal transition, angiogenesis, and immune surveillance escape. Moreover, host organs could develop premetastatic niches and be more vulnerable to cancer cell colonization, adaptation and growth.

Author : Wayne Kyle Spitzer
Publisher : Hobb's End Press
Page : 132 pages
File Size : 43,8 Mb
Release : 2023-11-11
Category : Fiction
ISBN : 8210379456XXX

Get Book

Dark Horses: The Magazine of Weird Fiction No. 22 | November 2023 by Wayne Kyle Spitzer Pdf

dark horse /ˈdärk ˈˌhôrs/ noun 1. a candidate or competitor about whom little is known but who unexpectedly wins or succeeds. "a dark-horse candidate" Join us for a monthly tour of writers who give as good as they get. From hard science-fiction to stark, melancholic apocalypses; from Lovecraftian horror to zombies and horror comedy; from whimsical interludes to tales of unlikely compassion--whatever it is, if it's weird, it's here. So grab a seat before the starting gun fires, pour yourself a glass of strange wine, and get ready for the running of the dark horses. In this issue: A+ TEETH Robert Nazar Arjoyan DACOIT, SON OF A NOBLE Ronit J. ERASURE (GOING NUCLEAR) Sylvia Woodham LAST RIDE ON THE NIGHT TRAIN Anthony Ferguson DEATH GRADER Wayne Kyle Spitzer NECROPOLIS John K. Peck THE AIR, BUT WITH HANDS Jake Williams MYGALOMORPHAE Clay Waters THE DROWNING POOL Vonnie Winslow Crist WOUNDS ARE LIPS WAITING TO BE KISSED Eric Nash

Author : Wayne Kyle Spitzer
Publisher : Hobb's End Press
Page : 130 pages
File Size : 47,8 Mb
Release : 2023-11-11
Category : Fiction
ISBN : 8210379456XXX

Get Book

Black Sheep: Unique Tales of Terror and Wonder No. 5 | November 2023 by Wayne Kyle Spitzer Pdf

Welcome to Black Sheep: Unique Tales of Terror and Wonder, an extraordinary anthology magazine that transcends the boundaries of science-fiction, fantasy, and horror. Prepare to embark on a thrilling journey through the darkest corners of the human imagination, where the ordinary becomes extraordinary, and the mundane transforms into a realm of unspeakable terror and awe-inspiring wonder. Within these pages, you'll discover a collection of captivating stories carefully curated to transport you to realms beyond the mundane. Each issue presents an array of unique tales crafted by talented visionaries, both established and emerging, who dare to defy conventions and push the boundaries of speculative fiction. Whether you're a seasoned lover of the fantastic or just curious to explore new frontiers, Black Sheep: Unique Tales of Terror and Wonder will be your guide through the realms of the extraordinary. Prepare to be enthralled, enchanted, haunted. So put on your dark sunglasses … and unleash your inner Black Sheep. In this issue: COBB’S CORNER J.A. Heath THE COLDEST RIDE IN THE DEAD OF WINTER Mike Sharlow GONE Josh Eure JON CARVER OF BARZOON, YOU MISUNDERSTOOD Graham J. Darling WHITE OF THE EYES Wayne Kyle Spitzer LONDON GHOSTS Lev Raphael HE’S STILL IN THE HOUSE Paul O’Neill THE CURE Michael Harper TRINITY HOME FOR THE GIFTED Michael Vance YOU SHOULDN’T READ THIS Atticus Hogan

Author : Testbook.com
Publisher : Testbook.com
Page : 11 pages
File Size : 52,8 Mb
Release : 2023-12-06
Category : Antiques & Collectibles
ISBN : 8210379456XXX

Get Book

Important Days and Events Current Affairs E-Book Nov 2023 PDF by Testbook.com Pdf

Learn about the important days and events from Nov 2023 with the Important Days and Events Current Affairs E-Book Nov 2023 PDF. Know about International Jaguar Day: 29 Nov, Red Planet Day: 28 Nov, Public Service Broadcasting Day: 12th Nov, etc.

Author : OECD
Publisher : OECD Publishing
Page : 261 pages
File Size : 49,5 Mb
Release : 2024-01-31
Category : Electronic
ISBN : 9789264579644

Get Book

OECD Health Policy Studies Beating Cancer Inequalities in the EU Spotlight on Cancer Prevention and Early Detection by OECD Pdf

This report addresses the latest trends in cancer incidence and mortality in the EU and reviews key cancer risk factors, cancer screening programmes and early diagnoses, and issues in the provision of high-quality cancer care.

Author : Miriam Cullen,Matthew Scott
Publisher : Taylor & Francis
Page : 162 pages
File Size : 49,7 Mb
Release : 2024-06-20
Category : Science
ISBN : 9781040040423

Get Book

Nordic Approaches to Climate-Related Human Mobility by Miriam Cullen,Matthew Scott Pdf

Academic discussion of climate‐related human mobility has understandably focused on the places where people are especially vulnerable to climate‐related harm: the Global South. Yet, the unique biophysical, legal and socio‐political characteristics of the Nordic region, as well as its roles as both ‘home’ and ‘host’ to climate‐related mobilities, justify its independent attention. Filling this lacuna, this collection is the first to address climate‐related human mobility in the Nordic region. It is a timely and much needed collection, which brings together leading and emerging voices from both academia and practice in a single volume, spanning policy and geographical breadth. Its chapters cover both regional approaches to the global phenomenon of climate mobility, such as the traditional role of the Nordic states as norm entrepreneurs and their representation in multilateral fora, and on‐the‐ground climate impacts unique to this region and their localised responses. Case studies include judicial decision‐making as it relates to climate‐related migration, insights into the local communication of climate risk, changes to Nordic development and climate policy, as well as climate‐related mobilities of Nordic Indigenous Peoples. This volume will be of great interest to students and scholars of disaster and climate studies, as well as climate‐related mobility, migration and displacement.

Author : Yewei Zhang,Houjuan Zhu,Qun Zhao,Chenyu Sun
Publisher : Frontiers Media SA
Page : 246 pages
File Size : 55,8 Mb
Release : 2024-04-11
Category : Medical
ISBN : 9782832547694

Get Book

Metabolic and Senescence Characteristics Associated with the Immune Microenvironment in Tumor Cells by Yewei Zhang,Houjuan Zhu,Qun Zhao,Chenyu Sun Pdf

A common feature of cancer metabolism is the ability to obtain essential nutrients from a nutrient-poor environment and use them to maintain viability as well as generate new biomass. Alterations in intracellular and extracellular metabolites can be accompanied by tumor-associated metabolic reprogramming with profound effects on gene expression, cell differentiation, and tumor microenvironment. In these cases, the metabolic microenvironment of the tumor itself can present an immunosuppressive environment that needs to be overcome. Specifically, it will help maximize the efficacy of cancer therapies by identifying targets that suppress or alter cancer metabolism to improve the tumor microenvironment nutrient availability or that modulate immune metabolism to bolster inflammation.

Author : Billy Jebaraj,Felix Seyfried,Michael Liew
Publisher : Frontiers Media SA
Page : 162 pages
File Size : 42,5 Mb
Release : 2024-05-10
Category : Medical
ISBN : 9782832548981

Get Book

Reviews in hematologic malignancies: 2023 by Billy Jebaraj,Felix Seyfried,Michael Liew Pdf

Author : Sarah El-Nakeep,Anup Kasi,Ahmed Sawabi Shwaky,Wangi Rachel,Htar Aung
Publisher : Frontiers Media SA
Page : 102 pages
File Size : 55,9 Mb
Release : 2023-11-24
Category : Science
ISBN : 9782832539538

Get Book

Hepatocellular carcinoma: from personalized medicine to practical guidelines by Sarah El-Nakeep,Anup Kasi,Ahmed Sawabi Shwaky,Wangi Rachel,Htar Aung Pdf

Hepatocellular carcinoma (HCC) is the most common primary liver cancer. HCC is the fourth cause of cancer-related mortality and the fifth most common cancer in the world. The prognosis and survival of patients depend mainly on the cancer stage at time of diagnosis. Earlier detection of the disease has seen improvement in treatment and disease-free survival over the last several decades. Currently, the only curable treatment for HCC is tumor resection or transplantation. These measures are strictly successful only if caught during early-stage HCC. Research has identified multiple molecular pathways involved in HCC on genetic, epigenetic, and proteomic levels. There has been a lot of research into designing drugs to specifically target these molecular pathways affected in patients, and thus contributing to personalized medical treatment. There is abundant bioinformatic research to document the extensive molecular pathways involved as well as drug docking techniques used to assess drug candidates for treating those affected pathways. These bioinformatic techniques result in identifying candidates suitable for further analysis in tissue and animal models and human trials.

Author : Megan Stephenson,Angela Gill
Publisher : Learning Matters
Page : 225 pages
File Size : 43,9 Mb
Release : 2024-04-19
Category : Education
ISBN : 9781529678406

Get Book

Training to be a Primary School Teacher: ITT and Beyond by Megan Stephenson,Angela Gill Pdf

Your essential coursebook for primary initial teacher training. Linked to the CCF and the ITTECF. This complete handbook supports your accredited primary initial teacher training (ITT) course. *Covers all areas of core content outlined in the ITT Core Content Framework and the Initial Teacher Training and Early Career Framework *Introduces key educational debates and a range of pedagogical perspectives on teaching and learning *Includes reflection activities to empower you to take control of your own learning and deepen your understanding *Supports your understanding of how the academic aspects of your ITT course link with your school-based experience *Provides you with opportunities to apply your knowledge in context *Enhances your understanding of what is required of you during ITT; ensuring you get the most out of your course