Target Product Profile For Therapy Of Neonatal Sepsis In High Resistance Settings

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Sepsis in Neonates and Children

Author : Luregn J. Schlapbach,Eric Giannoni
Publisher : Frontiers Media SA
Page : 261 pages
File Size : 44,7 Mb
Release : 2021-01-04
Category : Medical
ISBN : 9782889663231

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Sepsis in Neonates and Children by Luregn J. Schlapbach,Eric Giannoni Pdf

Early-onset Neonatal Sepsis

Author : Anonim
Publisher : Unknown
Page : 0 pages
File Size : 46,8 Mb
Release : 2010
Category : Electronic
ISBN : OCLC:733963734

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Early-onset Neonatal Sepsis by Anonim Pdf

Pocket Book of Hospital Care for Children

Author : World Health Organization
Publisher : World Health Organization
Page : 442 pages
File Size : 40,6 Mb
Release : 2013
Category : Medical
ISBN : 9789241548373

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Pocket Book of Hospital Care for Children by World Health Organization Pdf

The Pocket Book is for use by doctors nurses and other health workers who are responsible for the care of young children at the first level referral hospitals. This second edition is based on evidence from several WHO updated and published clinical guidelines. It is for use in both inpatient and outpatient care in small hospitals with basic laboratory facilities and essential medicines. In some settings these guidelines can be used in any facilities where sick children are admitted for inpatient care. The Pocket Book is one of a series of documents and tools that support the Integrated Managem.

Oral Cephalosporins

Author : Robert C. Moellering
Publisher : S Karger Ag
Page : 0 pages
File Size : 51,6 Mb
Release : 1995
Category : Medical
ISBN : 3805561636

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Oral Cephalosporins by Robert C. Moellering Pdf

This volume provides an excellent survey of the chemistry, microbiology, pharmacology and clinical use of the oral cephalosporins in general and the newer agents in particular. The cephalosporins have long provided satisfactory treatment for many disorders without causing serious side effects; and over the past fifty years forms with different antimicrobial, pharmacologic and toxicologic properties have been developed. Despite the broad spectrum of their activity against a large variety of gram-positive and gram-negative bacteria, the third-generation oral cephalosporins including the prodrug esters do not work against Pseudomonas aeruginosa, methicillin-resistant staphylococci, enterococci or Bacteroides species. Many, however, are suitable for treating infections of the respiratory and urinary tracts and of the skin and its structure, as well as certain sexually-transmitted diseases. Authors consider other possible uses, against multi-resistant Enterobacteriaceae for instance, but also point out the limitations of the oral cephalosporins. For those working in the fields of infectious disease, bacteriology, chemotherapy, pharmaceutics and pharmacokinetics, this book is a valuable source of authoritative information.

Sepsis Management in Resource-limited Settings

Author : Arjen M. Dondorp,Martin W. Dünser,Marcus J. Schultz
Publisher : Springer
Page : 216 pages
File Size : 49,8 Mb
Release : 2019-02-08
Category : Medical
ISBN : 9783030031435

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Sepsis Management in Resource-limited Settings by Arjen M. Dondorp,Martin W. Dünser,Marcus J. Schultz Pdf

This book is open access under a CC BY 4.0 license. It constitutes a unique source of knowledge and guidance for all healthcare workers who care for patients with sepsis and septic shock in resource-limited settings. More than eighty percent of the worldwide deaths related to sepsis occur in resource-limited settings in low and middle-income countries. Current international sepsis guidelines cannot be implemented without adaptations towards these settings, mainly because of the difference in local resources and a different spectrum of infectious diseases causing sepsis. This prompted members of the Global Intensive Care working group of the European Society of Intensive Care Medicine (ESICM) and the Mahidol-Oxford Tropical Medicine Research Unit (MORU, Bangkok, Thailand) - among which the Editors – to develop with an international group of experts a comprehensive set of recommendations for the management of sepsis in resource-limited settings. Recommendations are based on both current scientific evidence and clinical experience of clinicians working in resource-limited settings. The book includes an overview chapter outlining the current challenges and future directions of sepsis management as well as general recommendations on the structure and organization of intensive care services in resource-limited settings. Specific recommendations on the recognition and management of patients with sepsis and septic shock in these settings are grouped into seven chapters. The book provides evidence-based practical guidance for doctors in low and middle income countries treating patients with sepsis, and highlights areas for further research and discussion.

Reducing Birth Defects

Author : Institute of Medicine,Board on Global Health,Committee on Improving Birth Outcomes
Publisher : National Academies Press
Page : 270 pages
File Size : 50,6 Mb
Release : 2003-10-27
Category : Medical
ISBN : 9780309166836

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Reducing Birth Defects by Institute of Medicine,Board on Global Health,Committee on Improving Birth Outcomes Pdf

Each year more than 4 million children are born with birth defects. This book highlights the unprecedented opportunity to improve the lives of children and families in developing countries by preventing some birth defects and reducing the consequences of others. A number of developing countries with more comprehensive health care systems are making significant progress in the prevention and care of birth defects. In many other developing countries, however, policymakers have limited knowledge of the negative impact of birth defects and are largely unaware of the affordable and effective interventions available to reduce the impact of certain conditions. Reducing Birth Defects: Meeting the Challenge in the Developing World includes descriptions of successful programs and presents a plan of action to address critical gaps in the understanding, prevention, and treatment of birth defects in developing countries. This study also recommends capacity building, priority research, and institutional and global efforts to reduce the incidence and impact of birth defects in developing countries.

Kucers' The Use of Antibiotics

Author : M. Lindsay Grayson,Sara E. Cosgrove,Suzanne Crowe,William Hope,James S. McCarthy,John Mills,Johan W. Mouton,David L. Paterson
Publisher : CRC Press
Page : 4894 pages
File Size : 44,8 Mb
Release : 2017-10-02
Category : Medical
ISBN : 9781498747967

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Kucers' The Use of Antibiotics by M. Lindsay Grayson,Sara E. Cosgrove,Suzanne Crowe,William Hope,James S. McCarthy,John Mills,Johan W. Mouton,David L. Paterson Pdf

Kucers’ The Use of Antibiotics is the definitive, internationally-authored reference, providing everything that the infectious diseases specialist and prescriber needs to know about antimicrobials in this vast and rapidly developing field. The much-expanded Seventh Edition comprises 4800 pages in 3 volumes in order to cover all new and existing therapies, and emerging drugs not yet fully licensed. Concentrating on the treatment of infectious diseases, the content is divided into four sections - antibiotics, anti-fungal drugs, anti-parasitic drugs, and anti-viral drugs - and is highly structured for ease of reference. Each chapter is organized in a consistent format, covering susceptibility, formulations and dosing (adult and pediatric), pharmacokinetics and pharmacodynamics, toxicity, and drug distribution, with detailed discussion regarding clinical uses - a feature unique to this title. Compiled by an expanded team of internationally renowned and respected editors, with expert contributors representing Europe, Africa, Asia, Australia, South America, the US, and Canada, the Seventh Edition adopts a truly global approach. It remains invaluable for anyone using antimicrobial agents in their clinical practice and provides, in a systematic and concise manner, all the information required when prescribing an antimicrobial to treat infection.

WHO Recommendations for Prevention and Treatment of Maternal Peripartum Infections

Author : World Health Organization
Publisher : World Health Organization
Page : 80 pages
File Size : 43,9 Mb
Release : 2016-02-12
Category : Medical
ISBN : 9789241549363

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WHO Recommendations for Prevention and Treatment of Maternal Peripartum Infections by World Health Organization Pdf

The goal of the present guideline is to consolidate guidance for effective interventions that are needed to reduce the global burden of maternal infections and its complications around the time of childbirth. This forms part of WHO's efforts towards improving the quality of care for leading causes of maternal death especially those clustered around the time of childbirth in the post-MDG era. Specifically it presents evidence-based recommendations on interventions for preventing and treating genital tract infections during labour childbirth or puerperium with the aim of improving outcomes for both mothers and newborns. The primary audience for this guideline is health professionals who are responsible for developing national and local health protocols and policies as well as managers of maternal and child health programmes and policy-makers in all settings. The guideline will also be useful to those directly providing care to pregnant women including obstetricians midwives nurses and general practitioners. The information in this guideline will be useful for developing job aids and tools for both pre- and inservice training of health workers to enhance their delivery of care to prevent and treat maternal peripartum infections.

Disease Control Priorities, Third Edition (Volume 6)

Author : King K. Holmes,Stefano Bertozzi,Barry R. Bloom,Prabhat Jha
Publisher : World Bank Publications
Page : 506 pages
File Size : 46,8 Mb
Release : 2017-11-06
Category : Medical
ISBN : 9781464805257

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Disease Control Priorities, Third Edition (Volume 6) by King K. Holmes,Stefano Bertozzi,Barry R. Bloom,Prabhat Jha Pdf

Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Antimicrobial Resistance in Developing Countries

Author : Aníbal de J. Sosa,Denis K. Byarugaba,Carlos F. Amábile-Cuevas,Po-Ren Hsueh,Samuel Kariuki,Iruka N. Okeke
Publisher : Springer Science & Business Media
Page : 554 pages
File Size : 47,8 Mb
Release : 2009-10-08
Category : Science
ISBN : 9780387893709

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Antimicrobial Resistance in Developing Countries by Aníbal de J. Sosa,Denis K. Byarugaba,Carlos F. Amábile-Cuevas,Po-Ren Hsueh,Samuel Kariuki,Iruka N. Okeke Pdf

Avoiding infection has always been expensive. Some human populations escaped tropical infections by migrating into cold climates but then had to procure fuel, warm clothing, durable housing, and crops from a short growing season. Waterborne infections were averted by owning your own well or supporting a community reservoir. Everyone got vaccines in rich countries, while people in others got them later if at all. Antimicrobial agents seemed at first to be an exception. They did not need to be delivered through a cold chain and to everyone, as vaccines did. They had to be given only to infected patients and often then as relatively cheap injectables or pills off a shelf for only a few days to get astonishing cures. Antimicrobials not only were better than most other innovations but also reached more of the world’s people sooner. The problem appeared later. After each new antimicrobial became widely used, genes expressing resistance to it began to emerge and spread through bacterial populations. Patients infected with bacteria expressing such resistance genes then failed treatment and remained infected or died. Growing resistance to antimicrobial agents began to take away more and more of the cures that the agents had brought.

Guidelines for the Prevention Care and Treatment of Persons with Chronic Hepatitis B Virus Infection

Author : WHO.,World Health Organization
Publisher : Unknown
Page : 0 pages
File Size : 48,9 Mb
Release : 2015
Category : Chronic diseases
ISBN : 9240694021

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Guidelines for the Prevention Care and Treatment of Persons with Chronic Hepatitis B Virus Infection by WHO.,World Health Organization Pdf

These are the first World Health Organization (WHO) guidelines for theprevention care and treatment of persons living with CHB infection andcomplement similar recent published guidance by WHO on the prevention care and treatment of infection due to the hepatitis C virus (HCV). In contrastto several recent international guidelines on the management of CHB infectionfrom the United States Europe Asia-Pacific and the United Kingdom (UK) theprimary audience for these WHO guidelines is country programme managers inall settings but particularly in LMICs to help plan the development and scale up.

Clinical Fluid Therapy in the Perioperative Setting

Author : Robert G. Hahn
Publisher : Cambridge University Press
Page : 309 pages
File Size : 54,6 Mb
Release : 2016-05-26
Category : Medical
ISBN : 9781107119550

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Clinical Fluid Therapy in the Perioperative Setting by Robert G. Hahn Pdf

The world's most renowned researchers in fluid management explain what you should know when providing infusion fluids to surgical patients.