Templated Organic Synthesis

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Templated Organic Synthesis

Author : François Diederich,Peter J. Stang
Publisher : John Wiley & Sons
Page : 431 pages
File Size : 50,7 Mb
Release : 2008-07-11
Category : Science
ISBN : 9783527613533

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Templated Organic Synthesis by François Diederich,Peter J. Stang Pdf

Template-controlled reactions allow the synthesis of complex molecules which would hardly be achievable through classical methods. This handbook offers authoratative information on how noncovalent and covalent templates can be effectively applied to control reaction rates as well as regio- and stereoselectivity. From the concepts of template control such as molecular imprinting, self-replication, and reversible tether-directed remote functionalization, the reader is led to template-based ring-closing reactions, oligomerizations, and multiple functionalizations and their application in the synthesis of supramolecular scaffolds and natural products. The editors and authors (J. F. Stoddart, G. Wulf, D. Lynn, R. Breslow. F. Diederich, just to name a few ) , all internationally recognized experts in their area, succeeded in presenting the manifold aspects of template-controlled synthesis in a didactic way, making this methodology accessible to a broad readership of organic synthetic chemists. Well-selected, reliable key experimental protocols and an up-to-date reference list underline the practical approach of this valuable handbook. Being the first book of its kind, it will serve as a pacemaker and stimulate future research.

Metal Mediated Template Synthesis of Ligands

Author : Otilia Costisor,W. Linert
Publisher : World Scientific
Page : 316 pages
File Size : 49,6 Mb
Release : 2004
Category : Science
ISBN : 9812794816

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Metal Mediated Template Synthesis of Ligands by Otilia Costisor,W. Linert Pdf

This book surveys the relatively new area of the synthesis of organic ligands when metal ions act as a template. In the last fifty years this field has undergone an explosive development, marked by a great amount of literature. The material in the book has been arranged according to the type of chemical reaction involved. In this frame, the basic principles of metal template reactions and the shape of the molecules are considered. Designed to satisfy the demands of students, young researchers doing their PhDs, and those working in the field of coordination chemistry, the book details the role of the metal ions and the specific properties of the formed complexes. Metal Mediated Template Synthesis of Ligands offers a comprehensive analysis with wide-ranging references and provides an extensive overview of research on metal-directed organic ligands over the past five decades. Contents: The Template Effect; Alkylation Reactions; Schiff Condensation; Mannich Condensation; Self Condensation of Nitriles; Self-Assembled Systems. Readership: Upper level undergraduates, graduate students, academics, researchers industrialists in inorganic, solid-state, supramolecular and organic chemistry.

Strategies and Tactics in Organic Synthesis

Author : Michael Harmata
Publisher : Academic Press
Page : 448 pages
File Size : 47,5 Mb
Release : 2004-06-15
Category : Science
ISBN : 0124502830

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Strategies and Tactics in Organic Synthesis by Michael Harmata Pdf

This title provides a forum for investigators to discuss their approach to the science and art of organic synthesis in a unique way. It provides a window into the world of design, function and synthesis that is at the leading edge of the molecular frontier.

Templates in Chemistry I

Author : Christoph A. Schalley,Fritz Vögtle,Karl Heinz Dötz
Publisher : Springer Science & Business Media
Page : 294 pages
File Size : 45,8 Mb
Release : 2005-01-13
Category : Science
ISBN : 3540225471

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Templates in Chemistry I by Christoph A. Schalley,Fritz Vögtle,Karl Heinz Dötz Pdf

With contributions by numerous experts

Strategies and Tactics in Organic Synthesis

Author : Michael Harmata
Publisher : Academic Press
Page : 436 pages
File Size : 52,6 Mb
Release : 2004-04-29
Category : Science
ISBN : 0080924328

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Strategies and Tactics in Organic Synthesis by Michael Harmata Pdf

A classic in the area of organic synthesis, Strategies and Tactics in Organic Synthesis provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a second-hand analysis, we are given stories that vividly demonstrate the power of the human endeavour known as organic synthesis and the creativity and tenacity of its practitioners. First hand accounts of each project tell of the excitement of conception, the frustration of failure and the joy experienced when either rational thought and/or good fortune give rise to successful completion of a project. In this book we learn how synthesis is really done and are educated, challenged and inspired by these stories, which portray the idea that triumphs do not come without challenges. We also learn that we can meet challenges to further advance the science and art of organic synthesis, driving it forward to meet the demands of society, in discovering new reactions, creating new designs and building molecules with atom and step economies that provide solutions through function to create a better world. - Personal accounts of research in organic chemistry. - Written by internationally renowned scientists. - Details state of the art organic synthesis.

Template Synthesis of Macrocyclic Compounds

Author : N. V. Gerbeleu,V. B. Arion,John P. Burgess
Publisher : John Wiley & Sons
Page : 574 pages
File Size : 45,6 Mb
Release : 2008-07-11
Category : Science
ISBN : 9783527613816

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Template Synthesis of Macrocyclic Compounds by N. V. Gerbeleu,V. B. Arion,John P. Burgess Pdf

The synthesis of macrocycles is an art in itself. Template-controlled synthesis provides elegant access to fascinating macrocyclic structures. Polyazamacrocycles, crown ethers, cryptands, rotaxanes, knots -- the range of macrocyclic compounds is as broad as their potential application as molecular switches, in ion exchange, electron transfer or catalysis. This book provides authoritative information on all aspects of template-controlled macrocyclizations. It covers in depth the current state of research on template processes - novel synthetic techniques and mechanistic approaches. The critical discussion of the diverse synthetic routes includes the detailed characterization of the broad variety of macrocyclic products. References to applications of macrocyclic compounds and over 1,500 citations make this handbook an indispensable tool for chemists in academia and industry. Researchers in organic and supramolecular chemistry, biotechnology, and inorganic chemistry will find inspiration for the design, synthesis, and myriad uses of new synthetic macrocycles.

Advances in Organic Synthesis

Author : Atta-ur-Rahman
Publisher : Bentham Science Publishers
Page : 513 pages
File Size : 42,7 Mb
Release : 2013-03-27
Category : Science
ISBN : 9781608050291

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Advances in Organic Synthesis by Atta-ur-Rahman Pdf

Advances in Organic Synthesis is a book series devoted to the latest advances in synthetic approaches towards challenging structures. It presents comprehensive articles written by eminent authorities on different synthetic approaches to selected target molecules and new methods developed to achieve specific synthetic transformations. Contributions are written by eminent scientists and each volume is edited by an authority in the field. Advances in Organic Synthesis is essential for all organic chemists in the academia and industry who wish to keep abreast of rapid and important developments in the field.

Templates in Chemistry III

Author : Peter Broekmann,Karl Heinz Dötz,Christoph A. Schalley
Publisher : Springer
Page : 260 pages
File Size : 52,8 Mb
Release : 2009-11-06
Category : Science
ISBN : 9783540896920

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Templates in Chemistry III by Peter Broekmann,Karl Heinz Dötz,Christoph A. Schalley Pdf

Volume 1 intends to shed light on a selection of aspects of "template chemistry" by combining chapters from areas as different as templated solid state synthesis, metal-mediated self assembly processes, organometallic synthesis, the formation of mechanically interlocked molecules, and, last but not least, the production of inorganic materials based on organic templates such as gels. Volume 2 provides an even broader overview of and deeper insight into the template topic adding new aspects and new views.

Principles of Organic Synthesis

Author : Richard O.C. Norman
Publisher : Routledge
Page : 1005 pages
File Size : 42,9 Mb
Release : 2017-10-19
Category : Science
ISBN : 9781351421720

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Principles of Organic Synthesis by Richard O.C. Norman Pdf

This book is designed for those who have had no more than a brief introduction to organic chemistry and who require a broad understanding of the subject. The book is in two parts. In Part I, reaction mechanism is set in its wider context of the basic principles and concepts that underlie chemical reactions: chemical thermodynamics, structural theory, theories of reaction kinetics, mechanism itself and stereochemistry. In Part II these principles and concepts are applied to the formation of particular types of bonds, groupings, and compounds. The final chapter in Part II describes the planning and detailed execution of the multi-step syntheses of several complex, naturally occurring compounds.

Organic Synthesis

Author : William A. Smit,Alekseĭ Feodosʹevich Bochkov,Ron Caple
Publisher : Royal Society of Chemistry
Page : 508 pages
File Size : 43,7 Mb
Release : 1998
Category : Education
ISBN : 0854045449

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Organic Synthesis by William A. Smit,Alekseĭ Feodosʹevich Bochkov,Ron Caple Pdf

The view of organic synthesis as "a concentrated expression of predictive ability and creative capacity" was advocated in the early 1950s. A concise and readable account of the role of synthesis in modern science, Organic Synthesis: The Science Behind the Art presents the general ideology of pursuits in the area of organic synthesis, and examines the methodologies that have evolved in the search for solutions to synthetic problems. This unique book details outstanding achievements of modern organic synthesis, not only for their scientific merits, but also for the aesthetic appeal of the target molecules chosen and the intrinsic beauty of the solutions to the problems posed. By judicious selection of data covering the main areas of synthetic explorations, this book serves to illustrate both the evolution of well-known approaches as well as recently emerged trends most likely to determine the future development of organic synthesis. Special attention is given to the consideration of principles of molecular design in promising and challenging areas of current research. Primarily aimed at advanced undergraduate and graduate students, Organic Synthesis: The Science Behind the Art will also be of interest to teachers, researchers and anyone requiring an introduction to the problems of organic synthesis.

Organic Chemistry in Action

Author : F. Serratosa
Publisher : Elsevier Health Sciences
Page : 436 pages
File Size : 40,8 Mb
Release : 1990-06-15
Category : Science
ISBN : UOM:39015018823073

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Organic Chemistry in Action by F. Serratosa Pdf

Contrary to all other books in the field of organic synthesis, this volume combines Corey's methodology, which is based on the concept of synthon and retrosynthetic analysis, with Evans' methodology based on the `Lapworth model' of alternating polarities. Using this approach, the formation of carbon-carbon bonds and the manipulation of functional groups are treated together, whereas the stereochemical aspects are considered separately. Emphasis is laid on the importance of rigid structures, whether in the starting materials, the synthetic intermediates or the transition states, as a means of controlling the stereochemistry of the organic compounds. Enclosed with the book is a copy of a miniprogram (CHAOS) for an IBM PC, or fully compatible computers, which is an interactive program, affording the beginner a fast and easy way of learning, exploring and looking for new synthetic schemes of molecules of moderate complexity. As a textbook on organic synthesis, this volume will be of immense value at university level.

Separations and Reactions in Organic Supramolecular Chemistry

Author : Fumio Toda,Roger Bishop
Publisher : John Wiley & Sons
Page : 250 pages
File Size : 47,6 Mb
Release : 2004-04-21
Category : Science
ISBN : 9780470020258

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Separations and Reactions in Organic Supramolecular Chemistry by Fumio Toda,Roger Bishop Pdf

A new volume in the "Perspectives in Supramolecular Chemistry" series focusing on separating supramolecular structures, a key step in supramolecular chemistry. Two guest editors have been at the forefront of the development of chromatographical methods to deal with supramolecular systems. Reactions of supramolecular structures show the way into the future of chemistry. Fumio Toda is one of the driving forces in the development of supramolecular separation systems. A practical title in the prestigious “Perspectives in Supramolecular Chemistry” series.

Encyclopedia of Physical Organic Chemistry, 6 Volume Set

Author : Zerong Wang,Uta Wille,Eusebio Juaristi
Publisher : John Wiley & Sons
Page : 4542 pages
File Size : 55,8 Mb
Release : 2017-04-17
Category : Science
ISBN : 9781118470459

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Encyclopedia of Physical Organic Chemistry, 6 Volume Set by Zerong Wang,Uta Wille,Eusebio Juaristi Pdf

Winner of 2018 PROSE Award for MULTIVOLUME REFERENCE/SCIENCE This encyclopedia offers a comprehensive and easy reference to physical organic chemistry (POC) methodology and techniques. It puts POC, a classical and fundamental discipline of chemistry, into the context of modern and dynamic fields like biochemical processes, materials science, and molecular electronics. Covers basic terms and theories into organic reactions and mechanisms, molecular designs and syntheses, tools and experimental techniques, and applications and future directions Includes coverage of green chemistry and polymerization reactions Reviews different strategies for molecular design and synthesis of functional molecules Discusses computational methods, software packages, and more than 34 kinds of spectroscopies and techniques for studying structures and mechanisms Explores applications in areas from biology to materials science The Encyclopedia of Physical Organic Chemistry has won the 2018 PROSE Award for MULTIVOLUME REFERENCE/SCIENCE. The PROSE Awards recognize the best books, journals and digital content produced by professional and scholarly publishers. Submissions are reviewed by a panel of 18 judges that includes editors, academics, publishers and research librarians who evaluate each work for its contribution to professional and scholarly publishing. You can find out more at: proseawards.com Also available as an online edition for your library, for more details visit Wiley Online Library

A Handbook for DNA-Encoded Chemistry

Author : Robert A. Goodnow, Jr.
Publisher : John Wiley & Sons
Page : 495 pages
File Size : 48,5 Mb
Release : 2014-04-28
Category : Science
ISBN : 9781118487686

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A Handbook for DNA-Encoded Chemistry by Robert A. Goodnow, Jr. Pdf

This book comprehensively describes the development and practice of DNA-encoded library synthesis technology. Together, the chapters detail an approach to drug discovery that offers an attractive addition to the portfolio of existing hit generation technologies such as high-throughput screening, structure-based drug discovery and fragment-based screening. The book: Provides a valuable guide for understanding and applying DNA-encoded combinatorial chemistry Helps chemists generate and screen novel chemical libraries of large size and quality Bridges interdisciplinary areas of DNA-encoded combinatorial chemistry – synthetic and analytical chemistry, molecular biology, informatics, and biochemistry Shows medicinal and pharmaceutical chemists how to efficiently broaden available “chemical space” for drug discovery Provides expert and up-to-date summary of reported literature for DNA-encoded and DNA-directed chemistry technology and methods

Organic Synthesis

Author : Jürgen-Hinrich Fuhrhop,Guangtao Li
Publisher : John Wiley & Sons
Page : 546 pages
File Size : 45,8 Mb
Release : 2003-03-14
Category : Science
ISBN : 3527302727

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Organic Synthesis by Jürgen-Hinrich Fuhrhop,Guangtao Li Pdf

Since it is one of the core disciplines, every student of organic chemistry will need to cover organic synthesis at some point. This third edition of an extremely well-received and proven textbook is specially written with advanced undergraduate and graduate students in mind, although it is equally useful for research chemists, too. 50% of the text is new and includes new chapters on combinatoric chemistry, non-covalent molecular assemblies and the use of the Internet for searching chemical compounds. The authors have chosen the methods included here for their efficiency, elegance, and didactic value and have highlighted important reactions within the text. From reviews of the second edition: 'The text is very readable, and the authors are especially gifted at explaining complex concepts clearly and succinctly...This book is highly recommended reading for anyone wishing to gain an overview of organic synthesis.' J. Am. Chem. Soc. With his preface, Noble prizewinner E. J. Corey has also endorsed this already highly acclaimed work.