Textbook Of Autoinflammation

Author : Philip J. Hashkes,Ronald M. Laxer,Anna Simon
Publisher : Springer
Page : 820 pages
File Size : 54,7 Mb
Release : 2019-02-13
Category : Medical
ISBN : 9783319986050

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Textbook of Autoinflammation by Philip J. Hashkes,Ronald M. Laxer,Anna Simon Pdf

This book, the first complete textbook on this novel field in Medicine, comprehensively covers the clinical presentation, pathogenesis, genetics, and latest management strategies for autoinflammatory disorders as well as the basic science of autoinflammation. Relevant concepts such as how translational science of genetics and immunology relates to the innate immune system and autoinflammation are covered. Descriptions of the monogenic and polygenic/complex diseases that fall under the umbrella of autoinflammatory diseases are provided. Further topics covered include the latest clinical and genetic diagnostic approaches, concepts on the relationship between autoinflammation and autoimmunity/immunodeficiency, the role of autoinflammation in cancer, treatments and management strategies for these diseases, and potential areas of future development. The Textbook of Autoinflammation systematically describes and reviews diagnostic and treatment options for autoinflammatory disorders as well as all aspects of the concept of autoinflammation, and represents a valuable resource for professionals in a variety of disciplines who encounter these patients or who study autoinflammation.

Author : Petros Efthimiou
Publisher : Springer
Page : 322 pages
File Size : 42,6 Mb
Release : 2019-01-04
Category : Medical
ISBN : 9783319969299

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Auto-Inflammatory Syndromes by Petros Efthimiou Pdf

This book provides an overview of auto-inflammatory syndromes, covering the underlying immune mechanisms that lead to their development, specific disease presentations, and clinical treatment guidelines. The book is divided into two sections, adult and pediatric, with chapters focusing on individuals diseases such as systemic arthritis, hyper-IgD, pap syndrome, idiopathic recurrent pericarditis, and familial Mediterranean fever. Chapters incorporate the most recent advances in disease pathophysiology and examine the underlying inductive and effector mechanisms and therapies that relate to each auto-inflammatory disorder at the genetic, molecular, cellular, and epidemiologic levels. The book also discusses the research behind auto-inflammatory disorders to offer detailed clinical guidelines regarding diagnostic techniques, treatment plans, and advice on how to best transition pediatric patients into adult treatment. This is an invaluable reference on auto-inflammatory syndromes for clinicians and researchers in pediatric and adult rheumatology and immunology.

Author : Dirk Holzinger,Raphaela Goldbach-Mansky,Dirk Foell,Marco Gattorno
Publisher : Frontiers Media SA
Page : 119 pages
File Size : 49,5 Mb
Release : 2021-11-24
Category : Medical
ISBN : 9782889716616

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Management of Autoinflammatory Diseases in Childhood by Dirk Holzinger,Raphaela Goldbach-Mansky,Dirk Foell,Marco Gattorno Pdf

Author : James T. Cassidy,Ross E Petty,Ronald M. Laxer,Carol B Lindsley
Publisher : Elsevier Health Sciences
Page : 817 pages
File Size : 43,8 Mb
Release : 2010-10-15
Category : Medical
ISBN : 9781437735963

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Textbook of Pediatric Rheumatology E-Book by James T. Cassidy,Ross E Petty,Ronald M. Laxer,Carol B Lindsley Pdf

Textbook of Pediatric Rheumatology examines the full spectrum of rheumatologic diseases and non-rheumatologic musculoskeletal disorders in children and adolescents, detailing the presentation, differential diagnosis, course, management, and prognosis of every major condition. Drs. James T. Cassidy, Ross E. Petty, Ronald M. Laxer, and Carol B. Lindsley discuss recent developments in diagnosis, treatment, genetics, immunology, imaging, and more. Diagnose and treat effectively through exhaustive reviews of the complex symptoms and signs and lab abnormalities that characterize these clinical disorders. Choose treatment protocols based on the best scientific evidence available today. Apply the knowledge and experience of the leading experts in the field. Keep current with coverage of new topics including macrophage activation syndrome, pediatric sarcoidosis, uveitis, imaging, and occupational and physical therapy. Tap into detailed discussions of recent advances in the field, new research on the immunologic mechanisms of inflammatory disease, and new developments on biologic treatments for arthritis in ten new chapters. Master complex concepts and key techniques with a full-color design and full-color illustrations.

Author : Ross E Petty, MD, PhD, FRCPC,Ronald M. Laxer,Carol B Lindsley, MD, FAAP, MACR,Lucy Wedderburn,Robert C Fuhlbrigge, MD PhD,Elizabeth D. Mellins
Publisher : Elsevier
Page : 768 pages
File Size : 51,9 Mb
Release : 2020-12-15
Category : Medical
ISBN : 0323636527

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Textbook of Pediatric Rheumatology by Ross E Petty, MD, PhD, FRCPC,Ronald M. Laxer,Carol B Lindsley, MD, FAAP, MACR,Lucy Wedderburn,Robert C Fuhlbrigge, MD PhD,Elizabeth D. Mellins Pdf

Offering up-to-date, comprehensive coverage of disease progression, diagnosis, management, and prognosis, Textbook of Pediatric Rheumatology is the definitive reference in the field. For physicians caring for children with rheumatic diseases, this revised 8th Edition is an unparalleled resource for the full spectrum of rheumatologic diseases and non-rheumatologic musculoskeletal disorders in children and adolescents. Global leaders in the field provide reliable, evidence-based guidance, highlighted by superb full-color illustrations that facilitate a thorough understanding of the science that underlies rheumatic disease. Offers expanded coverage of autoinflammatory diseases, plus new chapters on Takayasu Arteritis and Other Vasculitides, Mechanistic Investigation of Pediatric Rheumatic Diseases, Genetics and Pediatric Rheumatic Diseases, and Global Issues in Pediatric Rheumatology. Reflects the changes in diagnosis, monitoring, and management that recent advances have made possible. Covers the latest information on small molecule treatment, biologics, biomarkers, epigenetics, biosimilars, and cell-based therapies, helping you choose treatment protocols based on the best scientific evidence available today. Features exhaustive reviews of the complex symptoms, signs, and lab abnormalities that characterize these clinical disorders. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Author : Christopher E. M. Griffiths,Jonathan Barker,Tanya O. Bleiker,Walayat Hussain,Rosalind C. Simpson
Publisher : John Wiley & Sons
Page : 22867 pages
File Size : 40,5 Mb
Release : 2024-04-16
Category : Medical
ISBN : 9781119709282

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Rook's Textbook of Dermatology by Christopher E. M. Griffiths,Jonathan Barker,Tanya O. Bleiker,Walayat Hussain,Rosalind C. Simpson Pdf

The latest edition of the world’s leading dermatology textbook Rook’s Textbook of Dermatology, 10th Edition is the most definitive, comprehensive and illustrated reference work in dermatology worldwide. Fully updated by experts from around the world, the book highlights the latest key evidence-based developments in pathogenesis, diagnosis and treatment of skin disorders. A highly intuitive resource and invaluable clinical companion for both those training and those fully qualified in dermatology, other highlights of Rook’s Textbook of Dermatology, 10th Edition include: 1. Comprehensive review of essential basic science, skin biology and pharmacology 2. More than 3000 clinical illustrations 3. Histological images to aid clinicopathological correlation 4. Up-to-date management details for all major dermatological disorders including emerging infections 5. All chapters fully referenced together with highlighted key references 6. Quick reference to essential facts, treatment ladders and management algorithms 7. Chapter dedicated to global skin health and inequalities 8. Description of the spectrum of presentations in dermatoses in skin of colour 9. Thorough review of surgical and aesthetic dermatology 10. On-line videos of practical procedures Rook's Textbook of Dermatology, 10th Edition is universally recognised as the most complete reference work for dermatologists of all experience levels and dermatology students worldwide.

Author : Robert M. Kliegman,Joseph W. St. Geme III
Publisher : Elsevier Health Sciences
Page : 5923 pages
File Size : 52,5 Mb
Release : 2024-03-29
Category : Medical
ISBN : 9780323883061

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Nelson Textbook of Pediatrics, 2-Volume - E-Book by Robert M. Kliegman,Joseph W. St. Geme III Pdf

Covering every aspect of general pediatric practice, as well as details for many pediatric subspecialists, Nelson Textbook of Pediatrics, 22nd Edition, brings you fully up to date with everything from rapidly changing diagnostic and treatment protocols to new technologies to the wide range of biologic, psychologic, and social problems faced by children today. Edited and written by experts and prominent members of the pediatric medical community, this comprehensive two-volume reference covers both the science and art of pediatric practice. It remains the reference of choice among pediatricians, pediatric residents, and others involved in the care of young patients, delivering the information you need in a concise, easy-to-use format for everyday reference and study. Features a user-friendly format with short chapters and subchapters that allow you to quickly find the information you need. Includes more than 60 new chapters on topics covering the impact of social factors on children’s health, the impact of genetic discoveries on understanding diagnosing and treating childhood diseases, updating of current evidenced based diagnostic and therapeutic approaches to childhood diseases, and more. Offers new and expanded information on gene therapy; interferonopathies; reactive infectious mucocutaneous eruption (RIME); e-cigarette or vaping use-associated lung injury (EVALI); monkeypox; food protein-induced enterocolitis syndrome (FPIES); signaling pathway disorders; ciliopathies; very early onset inflammatory bowel disease; Epstein-Barr virus susceptibility disorders; marijuana smoke exposure; and much more. Features hundreds of new figures and tables throughout for visual clarity and quick reference, real-time videos, and regular updates online, written exclusively for Nelson. Provides fresh perspectives from two new associate editors: Abigail M. Schuh and Cara L. Mack, both of Medical College of Wisconsin. Remains your indispensable source for definitive, evidence-based answers on every aspect of pediatric care. Any additional digital ancillary content may publish up to 6 weeks following the publication date.

Author : Peter H. Hoeger,Veronica Kinsler,Albert C. Yan,Christine Bodemer,Margarita Larralde,David Luk,Vibhu Mendiratta,Diana Purvis
Publisher : John Wiley & Sons
Page : 0 pages
File Size : 40,9 Mb
Release : 2019-12-16
Category : Medical
ISBN : 9781119142195

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Harper's Textbook of Pediatric Dermatology, 2 Volume Set by Peter H. Hoeger,Veronica Kinsler,Albert C. Yan,Christine Bodemer,Margarita Larralde,David Luk,Vibhu Mendiratta,Diana Purvis Pdf

A consummate classic with a fresh approach to pediatric dermatology Children ́s skin is different. Maturation affects the epidermal barrier, the cutaneous microbiome, adnexal structures, vasculature, and transcutaneous absorption of drugs. The immature skin is more susceptible to pathogens and environmental disruption. Many genetic disorders are either present at birth or manifest early in childhood. Skin diseases thus present differently in children than in adults. Pediatric dermatology has seen significant advances over the last decade, particularly in the field of molecular genetics research, which has furthered our understanding of the pathogenesis of many skin diseases and the development of new approaches to treatment. This fourth edition of the Harper classic provides state-of-the-art information on all aspects of skin disease in children. It covers the diagnosis and treatment of all conditions - both common and rare - with a consistently evidence-based approach. Existing content has been refreshed and fully updated to reflect emerging thinking and to incorporate the latest in research and clinical data - especially at the genetic level. This new fourth edition includes: Greater focus on the genetics behind skin disease, including new genes/genodermatoses, progress in genetic analysis, and stem cell transplants Increased coverage of lasers and other technologies used to treat skin disease More summary tables, learning points, tables of differential diagnosis, and clinical algorithms for diagnosis and management Additional online features, including patient information links and multiple choice questions Harper's Textbook of Pediatric Dermatology delivers crucial clinical insights and up-to-date research information that spans the breadth of the field. As the most comprehensive reference book on this subject available, this revised fourth edition will support and guide the daily practice of both dermatologists and pediatricians across the world.

Author : Ross E. Petty
Publisher : Unknown
Page : 128 pages
File Size : 53,9 Mb
Release : 2016
Category : Musculoskeletal system
ISBN : 032324145X

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Cassidy and Petty's textbook of pediatric rheumatology by Ross E. Petty Pdf

Author : Gary S. Firestein,Ralph C. Budd,Sherine E Gabriel,Iain B McInnes,James R. O'Dell
Publisher : Elsevier Health Sciences
Page : 2742 pages
File Size : 55,6 Mb
Release : 2020-07-05
Category : Medical
ISBN : 9780323639217

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Firestein & Kelley’s Textbook of Rheumatology by Gary S. Firestein,Ralph C. Budd,Sherine E Gabriel,Iain B McInnes,James R. O'Dell Pdf

Through 10 outstanding editions, Kelley & Firestein’s Textbook of Rheumatology has provided authoritative, in-depth guidance in rheumatology with an ideal balance of basic science and clinical application. The 11th Edition of this classic text continues this tradition of excellence, while keeping you abreast of recent advances in genetics and the microbiome, new therapies such as biologics and biosimilars, and other rapid changes in the field. It provides comprehensive, global coverage of all aspects of diagnosis, screening, and treatment in both adults and children, in a user-friendly, full color reference. Covers everything from basic science, immunology, anatomy, and physiology to diagnostic tests, procedures, and specific disease processes—including key data on therapeutic outcomes to better inform clinical decision making. Includes new chapters on Innate Lymphoid Cells and Natural Killer Cells, Pathogenesis of Inflammasome Mediated Diseases, Bisphosphonates, Ultrasound Evaluation of the Musculoskeletal System, and Evaluation of Monoarticular and Polyarticular Arthritis. Features 1,200 high-quality illustrations, including superb line art, quick-reference tables, and full-color clinical photographs. Shares the knowledge and expertise of internationally renowned scientists and clinicians, including new editor Dr. Gary Koretzky, specialist in immunology and rheumatology. Demonstrates the complete musculoskeletal exam in online videos, including abnormal findings and the arthroscopic presentation of diseased joints.

Author : Ross E. Petty,Ronald M. Laxer,Carol B Lindsley,Lucy Wedderburn,Robert C Fuhlbrigge,Elizabeth D. Mellins
Publisher : Elsevier Health Sciences
Page : 1043 pages
File Size : 49,7 Mb
Release : 2020-12-03
Category : Medical
ISBN : 9780323636537

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Textbook of Pediatric Rheumatology by Ross E. Petty,Ronald M. Laxer,Carol B Lindsley,Lucy Wedderburn,Robert C Fuhlbrigge,Elizabeth D. Mellins Pdf

Offering up-to-date, comprehensive coverage of disease progression, diagnosis, management, and prognosis, Textbook of Pediatric Rheumatology is the definitive reference in the field. For physicians caring for children with rheumatic diseases, this revised 8th Edition is an unparalleled resource for the full spectrum of rheumatologic diseases and non-rheumatologic musculoskeletal disorders in children and adolescents. Global leaders in the field provide reliable, evidence-based guidance, highlighted by superb full-color illustrations that facilitate a thorough understanding of the science that underlies rheumatic disease. Offers expanded coverage of autoinflammatory diseases, plus new chapters on Takayasu Arteritis and Other Vasculitides, Mechanistic Investigation of Pediatric Rheumatic Diseases, Genetics and Pediatric Rheumatic Diseases, and Global Issues in Pediatric Rheumatology. Reflects the changes in diagnosis, monitoring, and management that recent advances have made possible. Covers the latest information on small molecule treatment, biologics, biomarkers, epigenetics, biosimilars, and cell-based therapies, helping you choose treatment protocols based on the best scientific evidence available today. Features exhaustive reviews of the complex symptoms, signs, and lab abnormalities that characterize these clinical disorders.

Author : Nader Rifai
Publisher : Elsevier Health Sciences
Page : 4232 pages
File Size : 40,7 Mb
Release : 2022-02-03
Category : Medical
ISBN : 9780323834674

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Tietz Textbook of Laboratory Medicine - E-Book by Nader Rifai Pdf

Use THE definitive reference for laboratory medicine and clinical pathology! Tietz Textbook of Laboratory Medicine, 7th Edition provides the guidance necessary to select, perform, and evaluate the results of new and established laboratory tests. Comprehensive coverage includes the latest advances in topics such as clinical chemistry, genetic metabolic disorders, molecular diagnostics, hematology and coagulation, clinical microbiology, transfusion medicine, and clinical immunology. From a team of expert contributors led by Nader Rifai, this reference includes access to wide-ranging online resources on Expert Consult — featuring the comprehensive product with fully searchable text, regular content updates, animations, podcasts, over 1300 clinical case studies, lecture series, and more. Authoritative, current content helps you perform tests in a cost-effective, timely, and efficient manner; provides expertise in managing clinical laboratory needs; and shows how to be responsive to an ever-changing environment. Current guidelines help you select, perform, and evaluate the results of new and established laboratory tests. Expert, internationally recognized chapter authors present guidelines representing different practices and points of view. Analytical criteria focus on the medical usefulness of laboratory procedures. Use of standard and international units of measure makes this text appropriate for any user, anywhere in the world. Expert Consult provides the entire text as a fully searchable eBook, and includes regular content updates, animations, podcasts, more than 1300 clinical case studies, over 2500 multiple-choice questions, a lecture series, and more. NEW! 19 additional chapters highlight various specialties throughout laboratory medicine. NEW! Updated, peer-reviewed content provides the most current information possible. NEW! The largest-ever compilation of clinical cases in laboratory medicine is included on Expert Consult. NEW! Over 100 adaptive learning courses on Expert Consult offer the opportunity for personalized education.

Author : Robert M. Kliegman,Joseph W. St. Geme III
Publisher : Elsevier Health Sciences
Page : 6667 pages
File Size : 42,8 Mb
Release : 2019-04-01
Category : Medical
ISBN : 9780323568883

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Nelson Textbook of Pediatrics E-Book by Robert M. Kliegman,Joseph W. St. Geme III Pdf

Welcome to the 21st Edition of Nelson Textbook of Pediatrics – the reference of choice among pediatricians, pediatric residents, and others involved in the care of young patients. This fully revised edition continues to provide the breadth and depth of knowledge you expect from Nelson, while also keeping you up to date with new advances in the science and art of pediatric practice. Authoritative and reader-friendly, it delivers the information you need in a concise, easy-to-use format for everyday reference and study. From rapidly changing diagnostic and treatment protocols to new technologies to the wide range of biologic, psychologic, and social problems faced by children today, this comprehensive reference keeps you on the cutting edge of the very best in pediatric care. Includes more than 70 new chapters, including Postural Orthostatic Tachycardia Syndrome (POTS), Rare and Undiagnosed Diseases, Approach to Mitochondrial Disorders, Electronic Nicotine Delivery Systems, Zika, update on Ebola, Epigenetics, Autoimmune Encephalitis, Global Health, Racism, Media Violence, Strategies for Health Behavior Change, Positive Parenting, and many more. Features hundreds of new figures and tables throughout for visual clarity and quick reference. Offers new and expanded information on CRISPR gene editing; LGBT health care; gun violence; vaccinations; immune treatment with CAR-T cells; new technology in imaging and genomics; new protocols in cancer, genetics, immunology, and pulmonary medicine; and much more. Provides fresh perspectives from four new associate editors: Nathan J. Blum of The Children’s Hospital of Philadelphia; Karen Wilson of Mt. Sinai School of Medicine in New York; Samir S. Shah of Cincinnati Children’s Hospital Medical Center; and Robert C. Tasker of Boston Children’s Hospital. Remains your indispensable source for definitive, evidence-based answers on every aspect of pediatric care.

Author : Robert M. Kliegman, MD,Bonita F. Stanton, MD,Joseph St. Geme, MD,Nina F Schor, MD, PhD
Publisher : Elsevier Health Sciences
Page : 5111 pages
File Size : 53,5 Mb
Release : 2015-04-22
Category : Medical
ISBN : 9781455775668

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Nelson Textbook of Pediatrics, 2-Volume Set by Robert M. Kliegman, MD,Bonita F. Stanton, MD,Joseph St. Geme, MD,Nina F Schor, MD, PhD Pdf

After more than 75 years, Nelson Textbook of Pediatrics remains your indispensable source for definitive, state-of-the-art answers on every aspect of pediatric care. Embracing the new advances in science as well as the time-honored art of pediatric practice, this classic reference provides the essential information that practitioners and other care providers involved in pediatric health care throughout the world need to understand to effectively address the enormous range of biologic, psychologic, and social problems that our children and youth may face. Brand-new chapters and comprehensive revisions throughout ensure that you have the most recent information on diagnosis and treatment of pediatric diseases based on the latest recommendations and methodologies. "The coverage of such a wide range of subjects relating to child health makes this textbook still the gold standard and companion for all pediatricians across the world." Reviewed by Neel Kamal, Sept 2015 "All in all, this is an excellent and detailed paediatric review textbook which represents excellent value for money..truly a textbook for the global community" Reviewed by glycosmedia.com, Sept 2015 Form a definitive diagnosis and create the best treatment plans possible using evidence-based medicine and astute clinical experiences from leading international authors-many new to this edition. A NEW two-volume layout provides superior portability and exceptional ease of use. Gain a more complete perspective. Along with a broader emphasis on imaging and molecular diagnoses and updated references, the new edition includes an increased focus on international issues to ensure relevance in pediatrics practice throughout the world. Effectively apply the latest techniques and approaches with complete updates throughout 35 new chapters, including: Innovations in Addressing Child Health and Survival in Low Income Settings; Developmental Domains and Theories of Cognition; The Reggio Emilia Educational Approach Catatonia ; Refeeding Syndrome; Altitude-associated Illness; Genetic Approaches to Rare and Undiagnosed Diseases; Healthcare?Associated Infections; Intrapartum and Peripartum Infections; Bath salts and other drugs of abuse; Small Fiber Polyneuropathy; Microbiome; Kingella kingae; Mitochondrial Neurogastrointestinal Encephalomyopathy; Nonalcoholic Fatty Liver Disease; Plagiocephaly; CNS Vasculitis; Anterior Cruciate Ligament Rupture; and Sports-Related Traumatic Brain Injury. Recognize, diagnose, and manage genetic and acquired conditions more effectively. A new Rehabilitation section with 10 new chapters, including: Evaluation of the Child for Rehabilitative Services; Severe Traumatic Brain Injury; Spinal Cord Injury and Autonomic Crisis Management; Spasticity; Birth Brachial Plexus Palsy; Traumatic and Sports-Related Injuries; Meningomyelocele; Health and Wellness for Children with Disabilities. Manage the transition to adult healthcare for children with chronic diseases through discussions of the overall health needs of patients with congenital heart defects, diabetes, and cystic fibrosis. Understand the principles of therapy and which drugs and dosages to prescribe for every disease. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Author : Ayşe Engin Arısoy,Emin Sami Arısoy,Nuray Bayar Muluk,Cemal Cingi,Armando G. Correa
Publisher : Springer Nature
Page : 1112 pages
File Size : 45,7 Mb
Release : 2023-12-12
Category : Medical
ISBN : 9783031384950

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Hearing Loss in Congenital, Neonatal and Childhood Infections by Ayşe Engin Arısoy,Emin Sami Arısoy,Nuray Bayar Muluk,Cemal Cingi,Armando G. Correa Pdf

This book provides a broader understanding of infectious diseases and hearing loss prevention and treatment in children. In addition to all the common infections, the book covers the prion diseases, the autoinflammatory syndromes, and diseases of unknown etiology. A specific chapter is dedicated to cochlear implant infections. The final part reviews the available therapeutic agents. Written by international experts, the book will appeal to a wide readership, from ENT and pediatrics trainees, to practitioners and researchers in these disciplines.