Auto Inflammatory Syndromes

Author : Petros Efthimiou
Publisher : Springer
Page : 322 pages
File Size : 42,7 Mb
Release : 2019-01-04
Category : Medical
ISBN : 9783319969299

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Auto-Inflammatory Syndromes by Petros Efthimiou Pdf

This book provides an overview of auto-inflammatory syndromes, covering the underlying immune mechanisms that lead to their development, specific disease presentations, and clinical treatment guidelines. The book is divided into two sections, adult and pediatric, with chapters focusing on individuals diseases such as systemic arthritis, hyper-IgD, pap syndrome, idiopathic recurrent pericarditis, and familial Mediterranean fever. Chapters incorporate the most recent advances in disease pathophysiology and examine the underlying inductive and effector mechanisms and therapies that relate to each auto-inflammatory disorder at the genetic, molecular, cellular, and epidemiologic levels. The book also discusses the research behind auto-inflammatory disorders to offer detailed clinical guidelines regarding diagnostic techniques, treatment plans, and advice on how to best transition pediatric patients into adult treatment. This is an invaluable reference on auto-inflammatory syndromes for clinicians and researchers in pediatric and adult rheumatology and immunology.

Author : Philip J. Hashkes,Ronald M. Laxer,Anna Simon
Publisher : Springer
Page : 820 pages
File Size : 53,7 Mb
Release : 2019-02-13
Category : Medical
ISBN : 9783319986050

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Textbook of Autoinflammation by Philip J. Hashkes,Ronald M. Laxer,Anna Simon Pdf

This book, the first complete textbook on this novel field in Medicine, comprehensively covers the clinical presentation, pathogenesis, genetics, and latest management strategies for autoinflammatory disorders as well as the basic science of autoinflammation. Relevant concepts such as how translational science of genetics and immunology relates to the innate immune system and autoinflammation are covered. Descriptions of the monogenic and polygenic/complex diseases that fall under the umbrella of autoinflammatory diseases are provided. Further topics covered include the latest clinical and genetic diagnostic approaches, concepts on the relationship between autoinflammation and autoimmunity/immunodeficiency, the role of autoinflammation in cancer, treatments and management strategies for these diseases, and potential areas of future development. The Textbook of Autoinflammation systematically describes and reviews diagnostic and treatment options for autoinflammatory disorders as well as all aspects of the concept of autoinflammation, and represents a valuable resource for professionals in a variety of disciplines who encounter these patients or who study autoinflammation.

Author : Alessandra Soriano,José Hernández-Rodríguez
Publisher : Frontiers Media SA
Page : 168 pages
File Size : 40,8 Mb
Release : 2020-08-07
Category : Electronic
ISBN : 9782889639304

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Autoinflammatory Diseases: From Genes To Bedside by Alessandra Soriano,José Hernández-Rodríguez Pdf

Author : Rolando Cimaz,Thomas J.A. Lehman
Publisher : Elsevier
Page : 300 pages
File Size : 47,9 Mb
Release : 2007-11-13
Category : Medical
ISBN : 0080553443

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Pediatrics in Systemic Autoimmune Diseases by Rolando Cimaz,Thomas J.A. Lehman Pdf

Many of the systemic autoimmune diseases seen in children are different from those seen in adults making them a special problem for physicians and scientists who care for the affected children and study their diseases. Benefiting both pediatric and adult rheumatologists, as well as physicians from other specialties, this volume covers the latest advances in pathogenesis and clinical management of common conditions seen in pediatric rheumatology practices.

Author : Gleb Slobodin,Yehuda Shoenfeld
Publisher : Springer Nature
Page : 391 pages
File Size : 44,7 Mb
Release : 2020-05-25
Category : Medical
ISBN : 9783030442347

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Rheumatic Disease in Geriatrics by Gleb Slobodin,Yehuda Shoenfeld Pdf

This book provides a practical guide to the diagnosis and management of rheumatic disease in geriatric patients. It details information on the effect of ageing on musculoskeletal and immune systems and specifies impact of a variety of inflammatory and degenerative rheumatic disorders on the elderly. The clinical diagnostic approach to an older individual with musculoskeletal complaints is a cornerstone of this book, which includes also insights into the most important comorbidities for this age and discusses in depth available treatments and rehabilitation tools. The symptoms, imaging features and recommendations on the interpretation of specific laboratory tests for rheumatic diseases in geriatrics are also covered. This book encompasses traditionally associated with older age conditions including temporal arteritis, polymyalgia rheumatica, osteoarthritis, as well as common systemic autoimmune diseases that can produce atypical manifestations in the elderly. It will enable the readers to develop a thorough understanding of how to deal with these patients in their clinical practice. Rheumatic Disease in Geriatrics: Diagnosis and Management systematically describes how to diagnose and treat geriatric patients with a variety of rheumatic conditions and is a valuable resource for all medical professionals involved.

Author : Kathleen E. Sullivan,E. Richard Stiehm
Publisher : Academic Press
Page : 1334 pages
File Size : 51,5 Mb
Release : 2020-05-23
Category : Medical
ISBN : 9780128172957

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Stiehm's Immune Deficiencies by Kathleen E. Sullivan,E. Richard Stiehm Pdf

Stiehm’s Immune Deficiencies: Inborn Errors in Immunity, Second Edition, is ideal for physicians and other caregivers who specialize in immunology, allergies, infectious diseases and pulmonary medicine. It provides a validated source of information for care delivery to patients, covering approaches to diagnosis that use both new genetic information and emphasize screening strategies. Management has changed dramatically over the past five years, so approaches to infection and autoimmunity are emphasized in an effort to improve outcomes and disseminate new information on the uses of targeted therapy. Covers immune deficiencies that are presented in a practical way, providing helpful information for active clinicians Fills an increasingly deep gap in the information available to clinicians Presents both clinical management and scientific advances for immune deficiencies Provides a primary resource for physicians in the field of immunodeficiencies Includes website access to a range of videos relevant to the topics discussed

Author : Haralampos M. Moutsopoulos,Evangelia Zampeli,Panayiotis G. Vlachoyiannopoulos
Publisher : Springer
Page : 187 pages
File Size : 48,8 Mb
Release : 2018-02-13
Category : Medical
ISBN : 9783319716046

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Rheumatology in Questions by Haralampos M. Moutsopoulos,Evangelia Zampeli,Panayiotis G. Vlachoyiannopoulos Pdf

This book covers all fields in rheumatology and aims to help readers comprehend, familiarize and evaluate their knowledge of the subject area. It contains short questions and concise answers on definitions, pathogenetic aspects, clinical and laboratory manifestations, differential diagnosis and the management of all rheumatic diseases. The book also provides questions and answers on major aspects of basic immunology, valuable for understanding underlying immunological mechanisms of autoimmune rheumatic diseases. Illustrations and images help present information in a clear and schematic way.

Author : Misha Rosenbach,Karolyn A. Wanat,Robert G. Micheletti,Laura A. Taylor
Publisher : Springer
Page : 415 pages
File Size : 40,8 Mb
Release : 2018-11-03
Category : Medical
ISBN : 9783319184494

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Inpatient Dermatology by Misha Rosenbach,Karolyn A. Wanat,Robert G. Micheletti,Laura A. Taylor Pdf

​​​ Inpatient Dermatology is a concise and portable resource that synthesizes the most essential material to help physicians with recognition, differential diagnosis, work-up, and treatment of dermatologic issues in the hospitalized patient. Complete with hundreds of clinical and pathologic images, this volume is both an inpatient dermatology atlas and a practical guide to day-one, initial work-up, and management plan for common and rare skin diseases that occur in the inpatient setting. Each chapter is a bulleted, easy-to-read reference that focuses on one specific inpatient dermatologic condition, with carefully curated clinical photographs and corresponding histopathologic images to aid readers in developing clinical-pathologic correlation for the dermatologic diseases encountered in the hospital. Before each subsection the editors share diagnostic pearls, explaining their approach to these challenging conditions. This book is structured to be useful to physicians, residents, and medical students. It spans dermatology, emergency medicine, internal medicine, infectious disease, and rheumatology. Inpatient Dermatology is the go-to guide for hospital-based skin diseases, making even the most complex inpatient dermatologic issues approachable and understandable for any clinician.

Author : Jonathan A. Bernstein
Publisher : Springer Nature
Page : 409 pages
File Size : 40,6 Mb
Release : 2021-01-28
Category : Medical
ISBN : 9783030571573

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Primary and Secondary Immunodeficiency by Jonathan A. Bernstein Pdf

This book provides a broad clinical overview of primary and secondary immunodeficiencies nested in clinical cases that will help the reader understand the approach to evaluation, diagnosis, and management of these challenging cases. Chapters begin with a comprehensive overview of immunodeficiencies to ground the reader in practical knowledge of the field and these complex conditions. Chapters cover B lymphocyte immunodeficiency, T cell immunodeficiency, immune dysregulation syndromes, and innate immune defects. They discuss a range of treatment options including gene therapy or bone marrow transplant. The book continues with a discussion on secondary immunodeficiencies and their treatment. Each chapter was written by authors with expertise related to different immunodeficiency disorders and provide a succinct overview of pathomechanisms, diagnosis, and treatment of a specific condition. Primary and Secondary Immunodeficiency will be an excellent resource for practicing allergists, hematologists, clinical immunologists, fellows, residents, and other clinicians who work with immunodeficiency patients.

Author : Rolando Cimaz
Publisher : Springer Nature
Page : 283 pages
File Size : 44,6 Mb
Release : 2019-10-29
Category : Medical
ISBN : 9783030190552

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Periodic and Non-Periodic Fevers by Rolando Cimaz Pdf

This book, written by very well-known opinion leaders in the field, covers all aspects of periodic and non –periodic fevers, and related disorders. The expression refers to several different auto-inflammatory diseases, showing similar symptoms–the primary symptom being a recurrent fever for an infectious cause cannot be found. The opening chapters give some historical hints, explain the genetic basis of the disease and provide insights into the pathogenesis derived from recent experimental studies and guides the reader through classification and nomenclature. A large part of the book is then devoted to a detailed description of the specific related diseases and their clinical presentations, the disease course, and potential complications in both pediatric and adult patients. The advice regarding treatment is based on the best currently available evidence in this constantly evolving area. The book is part of Springer’s series Rare Diseases of the Immune System, which presents recently acquired knowledge on pathogenesis, diagnosis, and therapy with the aim of promoting a more holistic approach to these conditions. Autoinflammatory diseases are hereditary disorders that are caused by single-gene defects in innate immune regulatory pathways and are characterized by a clinical and biological inflammatory syndrome in which there is limited, if any, evidence of autoimmunity. Periodic and Non-Periodic Fevers will be an invaluable source of up-to-date information for all practitioners involved in the care of patients with these disease.

Author : Bo Shen
Publisher : Academic Press
Page : 380 pages
File Size : 41,7 Mb
Release : 2018-01-16
Category : Medical
ISBN : 9780128113899

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Interventional Inflammatory Bowel Disease: Endoscopic Management and Treatment of Complications by Bo Shen Pdf

Interventional Inflammatory Bowel Diseases: Endoscopic Management and Treatment of Complications covers the preparation, principle, techniques, and damage control of complications in endoscopic therapy, providing the ultimate guidance in endoscopic management of IBD. With contributions from a panel of international leading experts in the field, perspectives are included from GI pathologists, GI radiologists, gastroenterologists, advanced endoscopists, IBD specialists and colorectal surgeons. Recommendations from experts are also included within each chapter. By bridging medical and surgical treatment modalities for IBD, this is the perfect reference for GI researchers, medical students, therapeutic GI endoscopists, IBD specialists, surgeons and advanced health care providers. Incorporates state-of-the-art of research in the area of therapeutic endoscopy in Crohn’s Disease and Ulcerative Colitis Makes the connection between the understanding of the complex nature and disease course of IBD with corresponding advanced endoscopic procedures Explores endoscopic treatment as the missing link between medical and surgical treatment for complex Crohn’s Disease and Ulcerative Colitis Contains access to videos demonstrating important procedural concepts

Author : Marinos C. Dalakas
Publisher : Butterworth-Heinemann
Page : 362 pages
File Size : 47,8 Mb
Release : 2013-10-22
Category : Health & Fitness
ISBN : 9781483163048

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Polymyositis and Dermatomyositis by Marinos C. Dalakas Pdf

Polymyositis and Dermatomyositis provides extensive information regarding Polymyositis and Dermatomyositis (PM/DM), which is described as a heterogeneous disease complex. This book is divided into four sections: Part I (Clinical Features) covers the classification of PM/DM, details of the clinical presentation, and the disease's association with the other connective tissue disorders and malignancies. Part II (Etiology and Mechanisms) covers advances in the immunopathology and viral etiology of PM/DM along with a frequently recognized entity: inclusion body myositis. Part III (Diagnosis and Treatment) covers the histologic, muscle enzyme histochemical, electron microscopic, and resin histology features of PM/DM along with those electromyographic features that could help make a more accurate diagnosis. Part IV (Overview) summarizes the issues that may not have been clear and highlights differing and unsettled views or present available data. This text is directed to clinicians in private practice or in academic institutions concerned with PM/DM patients, including neurologists, rheumatologists, pediatricians, dermatologists, physiatrists, and neuromuscular investigators. This book is intended as well for neuromuscular pathologists who interpret muscle biopsy specimens and electromyographers who perform EMG studies to help determine the clinical diagnosis. Researchers in immunology and immunopathology of neuromuscular diseases will find discussions in this book invaluable.

Author : Carlo Perricone,Yehuda Shoenfeld
Publisher : Academic Press
Page : 728 pages
File Size : 55,6 Mb
Release : 2019-02-15
Category : Medical
ISBN : 9780128143070

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Mosaic of Autoimmunity by Carlo Perricone,Yehuda Shoenfeld Pdf

The Mosaic of Autoimmunity: The Novel Factors of Autoimmune Diseases describes the multifactorial origin and diversity of expression of autoimmune diseases in humans. The term implies that different combinations of factors in autoimmunity produce varying and unique clinical pictures in a wide spectrum of autoimmune diseases. Most of the factors involved in autoimmunity can be categorized into four groups: genetic, immune defects, hormonal and environmental factors. In this book, the environmental factors are reviewed, including infectious agents, vaccines as triggers of autoimmunity, smoking and its relationship with rheumatoid arthritis, systemic lupus erythematosus, thyroid disease, multiple sclerosis and inflammatory bowel diseases. An entirely new syndrome, the autoimmune/inflammatory syndrome induced by adjuvants (ASIA), is also included, along with other diseases that are now recognized as having an autoimmune etiopathogenesis. Highlights the concept of the mosaic of autoimmune manifestations Includes new visions on unsuspected molecules Provides updated knowledge to physicians helping patients with autoimmune diseases Presents thorough, up-to-date information on specific diseases, along with clinical applications

Author : Dirk Holzinger,Raphaela Goldbach-Mansky,Dirk Foell,Marco Gattorno
Publisher : Frontiers Media SA
Page : 119 pages
File Size : 42,8 Mb
Release : 2021-11-24
Category : Medical
ISBN : 9782889716616

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Management of Autoinflammatory Diseases in Childhood by Dirk Holzinger,Raphaela Goldbach-Mansky,Dirk Foell,Marco Gattorno Pdf

Author : Mohammad Ali El-Darouti,Faiza Mohamed Al-Ali
Publisher : Springer Nature
Page : 567 pages
File Size : 50,5 Mb
Release : 2019-08-28
Category : Medical
ISBN : 9783030218553

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Challenging Cases in Dermatology Volume 2 by Mohammad Ali El-Darouti,Faiza Mohamed Al-Ali Pdf

This book comprehensively covers a range of challenging cases in dermatology. It provides easy to follow guidance on how to successfully diagnose and treat a range of unusual diseases with a range of figures with informative legends and clinical data focused exercises to enable the reader to gain confidence and a deep understanding of why the diagnostic and treatment procedures taken in each case were chosen. Cases covered include follicular disorders, melanocytic diseases, vascular tumors, cutaneous lymphomas, and bullous diseases. This second volume of Challenging Cases in Dermatology systematically describes a range of unusual and rare clinical cases in dermatology. It is therefore a valuable resource for all trainee and practising dermatologists looking to further develop their knowledge and understanding of how to successfully diagnose and treat rare and challenging diseases.