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Author : Charles Owens Wilson,Ole Gisvold,Robert F. Doerge
Publisher : Lippincott Williams & Wilkins
Page : 1140 pages
File Size : 42,7 Mb
Release : 1977
Category : Chemistry, Organic
ISBN : UCAL:B4329678
Author : Charles Owens Wilson,Robert F. Doerge,Ole Gisvold
Publisher : Unknown
Page : 1085 pages
File Size : 50,9 Mb
Release : 1977
Category : Chemistry, Organic
ISBN : OCLC:848206975
Author : Charles Owens Wilson
Publisher : Unknown
Page : 0 pages
File Size : 54,6 Mb
Release : 2011
Category : Chemistry, Organic
ISBN : 0781779294
For over half a century, Wilson and Gisvold's Textbook of Organic Medicinal and Pharmaceutical Chemistry has served the discipline of medicinal chemistry for both graduate and undergraduate pharmacy and chemistry students as well as practicing pharmacists. Fully updated for the Twelfth Edition, the book begins with the fundamental principles of chemistry, biochemistry, and biology that underlie the discipline of medicinal chemistry. These principles are then applied to understanding the properties, mode of action, therapeutic applications, and limitations of various pharmaceutical agents. The subject matter is organized by pharmaceutical and therapeutic classes, providing a bridge between the basic sciences and clinical practice. The text contains many tables for quick reference to names, formulations, dosages, and applications. This edition includes chapter review questions and cases. A companion website provides online updates of medicinal chemistry structures and an image bank for faculty.
Author : T. C. Daniels
Publisher : Unknown
Page : 1078 pages
File Size : 47,9 Mb
Release : 1971
Category : Chemistry, Organic
ISBN : 0397520557
Author : Charles Owens Wilson
Publisher : Unknown
Page : 1085 pages
File Size : 49,8 Mb
Release : 1977
Category : Chemistry, Organic
ISBN : LCCN:81012385
Author : Paul M. Dewick
Publisher : John Wiley & Sons
Page : 711 pages
File Size : 44,8 Mb
Release : 2013-03-20
Category : Science
ISBN : 9781118681961
Essentials of Organic Chemistry is an accessible introduction to the subject for students of Pharmacy, Medicinal Chemistry and Biological Chemistry. Designed to provide a thorough grounding in fundamental chemical principles, the book focuses on key elements of organic chemistry and carefully chosen material is illustrated with the extensive use of pharmaceutical and biochemical examples. In order to establish links and similarities the book places prominence on principles and deductive reasoning with cross-referencing. This informal text also places the main emphasis on understanding and predicting reactivity rather than synthetic methodology as well as utilising a mechanism based layout and featuring annotated schemes to reduce the need for textual explanations. * tailored specifically to the needs of students of Pharmacy Medical Chemistry and Biological Chemistry * numerous pharmaceutical and biochemical examples * mechanism based layout * focus on principles and deductive reasoning This will be an invaluable reference for students of Pharmacy Medicinal and Biological Chemistry.
Author : Richard B. Silverman
Publisher : Elsevier
Page : 650 pages
File Size : 50,7 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780080513379
Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes in the drug industry over the past decade, and includes chapter problems and other elements that make the book more useful for course instruction. New edition includes new chapter problems and exercises to help students learn, plus extensive references and illustrations Clearly presents an organic chemist's perspective of how drugs are designed and function, incorporating the extensive changes in the drug industry over the past ten years Well-respected author has published over 200 articles, earned 21 patents, and invented a drug that is under consideration for commercialization
Author : Marc Harrold,Robin Zavod
Publisher : ASHP
Page : 405 pages
File Size : 53,7 Mb
Release : 2013-01-18
Category : Medical
ISBN : 9781585283644
Medicinal chemistry is a complex topic. Written in an easy to follow and conversational style, Basic Concepts in Medicinal Chemistry focuses on the fundamental concepts that govern the discipline of medicinal chemistry as well as how and why these concepts are essential to therapeutic decisions. The book emphasizes functional group analysis and the basics of drug structure evaluation. In a systematic fashion, learn how to identify and evaluate the functional groups that comprise the structure of a drug molecule and their influences on solubility, absorption, acid/base character, binding interactions, and stereochemical orientation. Relevant Phase I and Phase II metabolic transformations are also discussed for each functional group. Key features include: • Discussions on the roles and characteristics of organic functional groups, including the identification of acidic and basic functional groups. • How to solve problems involving pH, pKa, and ionization; salts and solubility; drug binding interactions; stereochemistry; and drug metabolism. • Numerous examples and expanded discussions for complex concepts. • Therapeutic examples that link the importance of medicinal chemistry to pharmacy and healthcare practice. • An overview of structure activity relationships (SARs) and concepts that govern drug design. • Review questions and practice problems at the end of each chapter that allow readers to test their understanding, with the answers provided in an appendix. Whether you are just starting your education toward a career in a healthcare field or need to brush up on your organic chemistry concepts, this book is here to help you navigate medicinal chemistry. About the Authors Marc W. Harrold, BS, Pharm, PhD, is Professor of Medicinal Chemistry at the Mylan School of Pharmacy, Duquesne University, Pittsburgh, PA. Professor Harrold is the 2011 winner of the Omicron Delta Kappa "Teacher of the Year" award at Duquesne University. He is also the two-time winner of the "TOPS" (Teacher of the Pharmacy School) award at the Mylan School of Pharmacy. Robin M. Zavod, PhD, is Associate Professor for Pharmaceutical Sciences at the Chicago College of Pharmacy, Midwestern University, Downers Grove, IL, where she was awarded the 2012 Outstanding Faculty of the Year award. Professor Zavod also serves on the adjunct faculty for Elmhurst College and the Illinois Institute of Technology. She currently serves as Editor-in-Chief of the journal Currents in Pharmacy Teaching and Learning.
Author : Rama Rao Nadendla
Publisher : New Age International
Page : 7 pages
File Size : 40,9 Mb
Release : 2007
Category : Chemistry, Organic
ISBN : 9788122415711
The Book Principles Of Organic Medicinal Chemistry Describes The Principles And Concepts Of Chemistry, Synthetic Schemes, Structure Activity Relationships, Mechanism Of Action And Clinical Uses Of Carbon Compounds In The Light Of Modern Trends. The Book Covers The Syllabai Of B. Pharmacy And M.Pharmacy Courses Of All Indian Universities.This Book Comprises Of 22 Chapters. Chapter 1 Gives An Introduction To Medicinal Chemistry, Chapter 2 Explain About The Basics On Principles Of Drug Action And Physicochemical Properties Of Organic Medicinal, Substances Are Elaborated In Chapter 3. The Concepts Of Prodrugs And Drug Metabolism Are Summarized In Chapter 4 And Chapter 5 Respectively. Chapter 6 To Chapter 22 Explains Chemistry, Properties, Mechanism Of Action, Structure Activity Relationships, Chemistry Of Newer Drugs And Clinical Uses Of Various Therapeutic Agents. At The End Of Book, A Set Of More Than 200 Essays And Short Questions And 225 Objective Questions With Answers Are St Strategically Designed.
Author : Joseph E. Rice
Publisher : Academic Press
Page : 224 pages
File Size : 49,5 Mb
Release : 2014-04-14
Category : Science
ISBN : 9780128008324
Organic Chemistry Concepts and Applications for Medicinal Chemistry provides a valuable refresher for understanding the relationship between chemical bonding and those molecular properties that help to determine medicinal activity. This book explores the basic aspects of structural organic chemistry without going into the various classes of reactions. Two medicinal chemistry concepts are also introduced: partition coefficients and the nomenclature of cyclic and polycyclic ring systems that comprise a large number of drug molecules. Given the systematic name of a drug, the reader is guided through the process of drawing an accurate chemical structure. By emphasizing the relationship between structure and properties, this book gives readers the connections to more fully comprehend, retain, apply, and build upon their organic chemistry background in further chemistry study, practice, and exams. Focused approach to review those organic chemistry concepts that are most important for medicinal chemistry practice and understanding Accessible content to refresh the reader's knowledge of bonding, structure, functional groups, stereochemistry, and more Appropriate level of coverage for students in organic chemistry, medicinal chemistry, and related areas; individuals seeking content review for graduate and medical courses and exams; pharmaceutical patent attorneys; and chemists and scientists requiring a review of pertinent material
Author : V. Alagarsamy
Publisher : BSP Books
Page : 1323 pages
File Size : 41,9 Mb
Release : 2020-06-20
Category : Science
ISBN : 9789389354782
Pharmaceutical organic chemistry is the main branch of organic chemistry deals with the study of preparation, structure and reactions of organic compounds. As it deals with all the chemical reactions related to life, study of Pharmaceutical organic chemistry is important. Application of Organic chemistry in the development of pharmaceuticals, resulted in evolving Pharmaceutical organic chemistry. Hence studying Organic chemistry and applying this knowledge in Pharmaceutical substances is called as Pharmaceutical organic chemistry. Organic chemistry forms the basis of biochemistry, in which various aspects of health and diseases are studied. The biochemical knowledge is very important for the practice of nutritional, medical and related life sciences. In addition Organic chemistry paved way for the development of medicinal chemistry, Pharmaceutical organic chemistry, bioinformatics, biotechnology, gene therapy, Pharmacology, pathology, chemical engineering, dental science and so on. Organic substances play such a vital role in our daily life that all of us should know about organic chemistry in order to understand the manner how it influence our life process.
Author : Jill Barber,Chris Rostron
Publisher : Oxford University Press
Page : 368 pages
File Size : 48,9 Mb
Release : 2013-07-25
Category : Medical
ISBN : 9780199655304
This volume provides a wide-ranging overview of organic chemistry as applied to the study and practice of pharmacy. Drugs are simply chemicals, so to fully understand their manufacture, formulation, and the way they work in our bodies, an understanding of organic compounds and their reactions is essential --
Author : Ali Mohammed
Publisher : Oxford and Ibh Publishers
Page : 475 pages
File Size : 46,8 Mb
Release : 2017-07-30
Category : Chemistry, Analytical
ISBN : 8123903650
Author : Thomas L. Lemke
Publisher : Unknown
Page : 156 pages
File Size : 46,7 Mb
Release : 1988
Category : Science
ISBN : UOM:39015013200848
Author : S.K. Bhasin,Reena Gupta
Publisher : Elsevier Health Sciences
Page : 812 pages
File Size : 46,8 Mb
Release : 2013-07-12
Category : Medical
ISBN : 9788131232675
Pharmaceutical Organic Chemistry has been written keeping in mind the severe need for a comprehensive text to meet the curriculum needs of the undergraduate pharmacy students. It not only provides all the curriculum topics to the students but also contains all the vital reactions/mechanisms that the students look for in an organic chemistry book. Entire subject matter has been written in a systematic and lucid style in simple language. All the basic concepts and fundamentals of organic chemistry have been explained with well-chosen examples. For better understanding of the subject matter, important points have been highlighted in the form of the textboxes titled as Remember, Learning Plus and Noteworthy Points, wherever required. Summary of the topics in the form of Memory Focus has been given at relevant places to help the students to revise the subject matter quickly. Stepwise mechanism of the reactions as per the syllabus has been illustrated, laying emphasis on the reactive intermediates involved. At the end of each chapter, Revision Questions including descriptive questions and short answer questions have been given for the students to practice. Multiple Choice Questions with answers have been included at the end of each chapter.
