Progenitor And Stem Cell Technologies And Therapies

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Progenitor and Stem Cell Technologies and Therapies

Anthony Atala
Progenitor and Stem Cell Technologies and Therapies Book PDF

Author : Anthony Atala
Publisher : Elsevier
Page : 561 pages
File Size : 43,5 Mb
Release : 2012-03-15
Category : Technology & Engineering
ISBN : 9780857096074

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Progenitor and Stem Cell Technologies and Therapies by Anthony Atala Pdf

Progenitor and stem cells have the ability to renew themselves and change into a variety of specialised types, making them ideal materials for therapy and regenerative medicine. Progenitor and stem cell technologies and therapies reviews the range of progenitor and stem cells available and their therapeutic application. Part one reviews basic principles for the culture of stem cells before discussing technologies for particular cell types. These include human embryonic, induced pluripotent, amniotic and placental, cord and multipotent stem cells. Part two discusses wider issues such as intellectual property, regulation and commercialisation of stem cell technologies and therapies. The final part of the book considers the therapeutic use of stem and progenitor cells. Chapters review the use of adipose tissue-derived stem cells, umbilical cord blood (UCB) stem cells, bone marrow, auditory and oral cavity stem cells. Other chapters cover the use of stem cells in therapies in various clinical areas, including lung, cartilage, urologic, nerve and cardiac repair. With its distinguished editor and international team of contributors, Progenitor and stem cell technologies and therapies is a standard reference for both those researching in cell and tissue biology and engineering as well as medical practitioners investigating the therapeutic use of this important technology. Reviews the range of progenitor and stem cells available and outlines their therapeutic application Examines the basic principles for the culture of stem cells before discussing technologies for particular cell types, including human embryonic, induced pluripotent, amniotic and placental, cord and multipotent stem cells Includes a discussion of wider issues such as intellectual property, regulation and commercialisation of stem cell technologies and therapies

Stem Cells and Cell Therapy

Mohamed Al-Rubeai,Mariam Naciri
Stem Cells and Cell Therapy Book PDF

Author : Mohamed Al-Rubeai,Mariam Naciri
Publisher : Springer Science & Business Media
Page : 194 pages
File Size : 46,8 Mb
Release : 2013-10-01
Category : Medical
ISBN : 9789400771963

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Stem Cells and Cell Therapy by Mohamed Al-Rubeai,Mariam Naciri Pdf

With the discovery of stem cells capable of multiplying indefinitely in culture and differentiating into many other cell types in appropriate conditions, new hopes were born in repair and replacement of damaged cells and tissues. The features of stem cells may provide treatment for some incurable diseases with some therapies are already in clinics, particularly those from adult stem cells. Some treatments will require large number of cells and may also require multiple doses, generating a growing demand for generating and processing large numbers of cells to meet the need of clinical applications. With this in mind, our aim is to provide a book on the subject of stem cells and cell therapy for researchers and students of cell biotechnology, bioengineering and bioproduction. This book is exceptional as it teaches researchers stem cells and cell therapy in that it covers the concepts and backgrounds necessary so that readers get a good understanding of the production of stem cells. The book covers three topics: The basics of stem cells and cell therapy, the use of stem cells for the treatment of human diseases, and stem cell processing. It includes chapters on neural and vascular stem vascular stem cell therapy, expansion engineering of embryonic stem cells, stem cell based production of blood cells and separation technologies for stem cells and cell therapy products. It is an informed and informative presentation of what modern research, science and engineering have learned about stem cells and their production and therapies. Addressing both the medical and production issues, this book is an invaluable contribution to having an academic and industrial understanding with respect to R&D and manufacturing of clinical grade stem cells.

Stem Cells in Regenerative Medicine

Alain A. Vertes,Nasib Qureshi,Arnold I. Caplan,Lee E. Babiss
Stem Cells in Regenerative Medicine Book PDF

Author : Alain A. Vertes,Nasib Qureshi,Arnold I. Caplan,Lee E. Babiss
Publisher : John Wiley & Sons
Page : 788 pages
File Size : 42,9 Mb
Release : 2015-12-02
Category : Science
ISBN : 9781119971399

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Stem Cells in Regenerative Medicine by Alain A. Vertes,Nasib Qureshi,Arnold I. Caplan,Lee E. Babiss Pdf

This book is a unique guide to emerging stem cell technologies and the opportunities for their commercialisation. It provides in-depth analyses of the science, business, legal, and financing fundamentals of stem cell technologies, offering a holistic assessment of this emerging and dynamic segment of the field of regenerative medicine. • Reviews the very latest advances in the technology and business of stem cells used for therapy, research, and diagnostics • Identifies key challenges to the commercialisation of stem cell technology and avenues to overcome problems in the pipeline • Written by an expert team with extensive experience in the business, basic and applied science of stem cell research This comprehensive volume is essential reading for researchers in cell biology, biotechnology, regenerative medicine, and tissue engineering, including scientists and professionals, looking to enter commercial biotechnology fields.

Advances in Stem Cell Therapy

Nagwa El-Badri
Advances in Stem Cell Therapy Book PDF

Author : Nagwa El-Badri
Publisher : Humana Press
Page : 310 pages
File Size : 47,5 Mb
Release : 2016-11-18
Category : Science
ISBN : 9783319291499

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Advances in Stem Cell Therapy by Nagwa El-Badri Pdf

The book reviews the main approaches for generation of differentiated cells from various types of stem cells, including embryonic, placental and cord blood stem cells through marrow, adipose tissue and dental pulp. The book starts with an overview of experimental protocols applied to generate insulin secreting cells, neural cells, heart cells, and other tissue specific cells ex vivo and in experimental animals. This is followed by exhaustive review of clinical trials in these pathologies. It continues with a comparison of the merits of successful transplantation in humans versus animal experimentation, and highlights the most promising clinical applications in the field. Special chapters are devoted to the topic of tissue engineering and modern synthetic and biological scaffolds. It is essential reading for scientists and researchers in tissue engineering and stem cell research as well as clinicians who are involved in developing or testing stem cell therapies.

Stem Cell Research and Therapeutics

Yanhong Shi,Dennis Clegg
Stem Cell Research and Therapeutics Book PDF

Author : Yanhong Shi,Dennis Clegg
Publisher : Springer Science & Business Media
Page : 336 pages
File Size : 45,8 Mb
Release : 2008-07-15
Category : Medical
ISBN : 9781402085024

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Stem Cell Research and Therapeutics by Yanhong Shi,Dennis Clegg Pdf

This book is an updated reference for one of the most exciting field of biomedical researches- Stem Cell Research and its therapeutic applications. Stem cell research holds great promise for the treatment of many human diseases that currently lack effective therapies. The set of chapters in this book provide insights into both basic stem cell biology and clinical applications of stem cell-based cell replacement therapies for a variety of human diseases, including cardiovascular diseases, neurological disorders, and li ver degeneration. It also covers novel technologies for the culture and differentiation of both human embryonic stem cells and adult tissue stem cells. This book summarizes our current state of knowledge in stem cell research and integrates basic stem cell biology with regenerative medicine in an overall context. It is an essential reference for students, postdoctoral fellows, academic and industrial scientists, and clinicians. v Acknowledgements The editors would like to thank Ms. Jill Brantley, Rose Chavarin, Alina Haas, and Emily Sun for their administrative assistance and proof-reading of this book. We would also like to thank all the authors for their contributions. vii The editors wish to dedicate this book to our mentors Ron Evans, Fred Gage, and, in memory of Daniel E. Koshland, Jr. Contents Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . v Acknowledgements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . vii Contributors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xi 1 Retinal Pigment Epithelial Cells: Development In Vivo and Derivation from Human Embryonic Stem Cells In Vitro for Treatment of Age-Related Macular Degeneration . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Dennis O. Clegg, David Buchholz, Sherry Hikita, Teisha Rowland, Qirui Hu, and Lincoln V.

Adult Stem Cell Therapies: Alternatives to Plasticity

Mariusz Z. Ratajczak
Adult Stem Cell Therapies Alternatives to Plasticity Book PDF

Author : Mariusz Z. Ratajczak
Publisher : Springer
Page : 271 pages
File Size : 43,8 Mb
Release : 2014-09-10
Category : Science
ISBN : 9781493910014

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Adult Stem Cell Therapies: Alternatives to Plasticity by Mariusz Z. Ratajczak Pdf

This timely volume explores various techniques for tissue and organ regeneration using stem cells isolated from adult tissues. It discusses alternative explanations of stem cell plasticity as well as current clinical results with adult stem cell therapies. It examines the presence of potential pluripotent stem cells in adult tissues, paracrine effects of stem cell therapies, and involvement of exosomes and microparticles into observed phenomena. Fifteen chapters, all written by noted leaders of their fields, focus on a variety of topics including cord blood and hematopoietic stem cells, skin and tissue organ regeneration, very small embryonic-like stem cells, and cell therapies in cardiology, neonatology, and neurology. Edited by Dr. Mariusz Ratajczak, an internationally known specialist in adult stem cell biology, Adult Stem Cell Therapies: Alternatives to Plasticity is an important addition to the Stem Cell Biology and Regenerative Medicine series.

Progenitor Cell Therapy for Neurological Injury

Charles S. Cox, Jr.
Progenitor Cell Therapy for Neurological Injury Book PDF

Author : Charles S. Cox, Jr.
Publisher : Springer Science & Business Media
Page : 208 pages
File Size : 52,9 Mb
Release : 2010-11-25
Category : Science
ISBN : 9781607619659

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Progenitor Cell Therapy for Neurological Injury by Charles S. Cox, Jr. Pdf

There are currently no reparative therapies for severe neurological injury, including brain injury, spinal cord injury and stroke. Actually, most treatments are designed simply to limit secondary damage. However, pre-clinical data supports the idea that exogenous stem and progenitor cells have the potential to promote a reparative response to severe neurological injuries. Progenitor Cell Therapy for Neurological Injury is a compilation of seminal essays that explore many unique aspects of neurological injury, focusing on the critical translational issues of cell delivery. Specifically, it discusses routes of administration, types of progenitor cells (alone and/or in combinations), timing of delivery and adjuncts to promote cell engraftment, survival and effectiveness. In addition, many chapters address measuring the effects of transplanted cells and cell tracking. The paradigms of how cell-based therapeutics affect neurological injury is changing rapidly. The developments in this field may ultimately offer realistic hope for improvement in patients with severe injuries. This book is a vital key toward unlocking those future treatments.

Resident Stem Cells and Regenerative Therapy

Regina Coeli dos Santos Goldenberg,Antonio Carlos Campos de Carvalho
Resident Stem Cells and Regenerative Therapy Book PDF

Author : Regina Coeli dos Santos Goldenberg,Antonio Carlos Campos de Carvalho
Publisher : Academic Press
Page : 306 pages
File Size : 45,5 Mb
Release : 2012-09-26
Category : Medical
ISBN : 9780124160125

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Resident Stem Cells and Regenerative Therapy by Regina Coeli dos Santos Goldenberg,Antonio Carlos Campos de Carvalho Pdf

Provides explanations of experiments with animal models and clinical trials that are transforming the field of regeneration.

Stem Cell Therapy

Erik V. Greer
Stem Cell Therapy Book PDF

Author : Erik V. Greer
Publisher : Nova Publishers
Page : 248 pages
File Size : 53,9 Mb
Release : 2006
Category : Biyomedikal araştorma
ISBN : 159454848X

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Stem Cell Therapy by Erik V. Greer Pdf

Among the many applications of stem cell research are nervous system diseases, diabetes, heart disease, auto-immune diseases as well as Parkinson's disease, end-stage kidney disease, liver failure, cancer, spinal cord injury, multiple sclerosis, Parkinson's disease, and Alzheimer's disease. Stem cells are self-renewing, unspecialised cells that can give rise to multiple types all of specialised cells of the body. Stem cell research also involves complex ethical and legal considerations since they involve adult, foetal tissue and embryonic sources. This new book brings together leading research from throughout the world in this frontier field.

Regenerative Medicine - from Protocol to Patient

Gustav Steinhoff
Regenerative Medicine from Protocol to Patient Book PDF

Author : Gustav Steinhoff
Publisher : Springer
Page : 455 pages
File Size : 47,5 Mb
Release : 2016-04-19
Category : Science
ISBN : 9783319276106

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Regenerative Medicine - from Protocol to Patient by Gustav Steinhoff Pdf

Regenerative medicine is the main field of groundbreaking medical development and therapy using knowledge from developmental and stem cell biology, as well as advanced molecular and cellular techniques. This collection of volumes on Regenerative Medicine: From Protocol to Patient, aims to explain the scientific knowledge and emerging technology as well as the clinical application in different organ systems and diseases. International leading experts from all over the world describe the latest scientific and clinical knowledge of the field of regenerative medicine. The process of translating science of laboratory protocols into therapies is explained in sections on regulatory, ethical and industrial issues. This collection is organized into five volumes: (1) Biology of Tissue Regeneration, (2) Stem Cell Science and Technology, (3) Tissue Engineering, Biomaterials and Nanotechnology, (4) Regenerative Therapies I, and (5) Regenerative Therapies II. The textbook gives the student, the researcher, the health care professional, the physician and the patient a complete survey on the current scientific basis, therapeutical protocols, clinical translation and practiced therapies in regenerative medicine. Volume 2 contains sixteen chapters addressing advanced knowledge on “Stem Cell Science and Technology” addressing basic classification technology, cell biology of stemness state and regulatory molecular pathways. Mechanisms and technology of cell programming are explained, as well as the pathology of cancer cells and dedifferentiation signalling. Pluripotent, multipotent germline and tissue specific human stem cells are classified and qualified according to their respective biological function or tissue regeneration. Leading stem cell scientists from all over the world explain advanced technology, latest knowledge, and clinical implications of human stem cell science in a unique, comprehensive and detailed outline.

Trends in Stem Cell Biology and Technology

Hossein Baharvand
Trends in Stem Cell Biology and Technology Book PDF

Author : Hossein Baharvand
Publisher : Springer Science & Business Media
Page : 420 pages
File Size : 49,7 Mb
Release : 2009-06-02
Category : Medical
ISBN : 9781603279048

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Trends in Stem Cell Biology and Technology by Hossein Baharvand Pdf

The study of stem cell research has recently gained the attention from a growing, multidisciplinary community of scientist; this exponential growth of interest is driven by the hope of discovering cures for several diseases through transplantation medicine. Trends in Stem Cells Biology and Technology aptly serves this developing community as it reveals new aspects of stem cell research by specifically covering studies focused on spermatogonial stem cells, uniparental embryonic stem cell lines, the generation of gametes from stem cells, reprogramming germ cells to stem cells, nuclear and somatic cell genetic reprogramming, tissue engineering and mechanotransduction of stem cells and finally the development of stem cell technologies for the treatment of deafness, heart disease, corneal injury and diabetes. With contributions by leading scientists and renowned scholars, Trends in Stem Cells Biology and Technology offers a wide audience cutting edge information at a crucial time in this ever expanding field.

Mesenchymal Stem Cells as New Candidates for Stemcell Based Dental Therapies

Patrick Kimuyu
Mesenchymal Stem Cells as New Candidates for Stemcell Based Dental Therapies Book PDF

Author : Patrick Kimuyu
Publisher : GRIN Verlag
Page : 20 pages
File Size : 45,5 Mb
Release : 2018-02-07
Category : Medical
ISBN : 9783668631489

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Mesenchymal Stem Cells as New Candidates for Stemcell Based Dental Therapies by Patrick Kimuyu Pdf

Project Report from the year 2018 in the subject Medicine - Medical Frontiers and Special Areas, grade: 1, Egerton University, language: English, abstract: This paper will provide a comprehensive review on the origin and types of MSCs in the dental tissue and the oral cavity. It will also discuss their therapeutic mechanisms that make them useful in dentistry and dental treatments. Over the past few decades, stem cell research has gained extensive scientific inquiry. This aspect is attributable to the significance of stem cells in tissue engineering. It is apparent that tissue regeneration has emerged as a reliable medical approach for the treatment of tissue disorders and injuries. Initially, embryonic stem cells were preferred as candidates for regenerative medicine because these cells can be induced to replicate in a pluripotent state. However, stem cell research involving embryonic stem cells has attracted immense controversy. It is also associated with legal and ethical issues, thus limiting the use of embryonic stem cells in regenerative medicine. Fortunately, the discovery of mesenchymal stem cells (MSCs), also referred to as adult stem cells, has restored promise for the development of stem cell therapies. Unlike embryonic stem cells, MSCs are free from legal and ethical concerns. MSCs are usually pluripotent progenitor cells that are generated in an array of tissues in both foetal and adult life. It is reported that these progenitor cells differentiate into cell types of the tissues that generate them, although studies indicate that they can differentiate cell types of other tissues. Currently, MSCs are used for regenerative therapies for a number of tissue disorders and injuries including bone regeneration. For instance, MSCs generated by the dental pulps and the oral cavity tissues have been found to possess the potential for dental tissue regeneration. These cells have also been found to useful in non-dental tissue repair.

Stem Cells: From Basic Research to Therapy, Volume Two

Federico Calegari,Claudia Waskow
Stem Cells From Basic Research to Therapy Volume Two Book PDF

Author : Federico Calegari,Claudia Waskow
Publisher : CRC Press
Page : 476 pages
File Size : 53,9 Mb
Release : 2014-06-03
Category : Medical
ISBN : 9781482219838

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Stem Cells: From Basic Research to Therapy, Volume Two by Federico Calegari,Claudia Waskow Pdf

The second volume in the Stem Cells series concentrates on the mechanisms of stem cell regeneration in the adult organism with a view towards understanding how lost tissue can be replaced during adulthood and aging. The second focus of this volume is on stem cell identification and manipulation, including applications in basic research, medicine, and industry. The book closes with an outlook on generalized approaches that can be used to solve legislative and ethical challenges.

Cell Therapy

George Morstyn,William Sheridan
Cell Therapy Book PDF

Author : George Morstyn,William Sheridan
Publisher : Cambridge University Press
Page : 656 pages
File Size : 43,9 Mb
Release : 1996-03-29
Category : Medical
ISBN : 0521473152

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Cell Therapy by George Morstyn,William Sheridan Pdf

Cell therapy is a rapidly developing area, drawing on cell biology, molecular biology, virology, immunology, cell quantitation techniques and biomedical engineering. It has potential in many clinical settings, in the treatment of cancer and other diseases. This volume in the series Cancer: Clinical Science in Practice examines the current state and future prospects of cell therapy, which seems likely to have an even more profound impact on health care than did the production of proteins by recombinant DNA technology. The coverage is broad, including the scientific principles of haematopoietic cell therapy, the technology of cell collection and preparation, current and likely future clinical applications of cell therapy, and the principles and practice of cellular immunotherapy. Up-to-date and authoritative, volumes in this series are intended for a wide audience of clinicians and researchers with an interest in the applications of biomedical science to the understanding and management of cancer.

Stem Cell Bioprocessing

Tiago G. Fernandes,M. Margardia Diogo,Joaquim M.S. Cabral
Stem Cell Bioprocessing Book PDF

Author : Tiago G. Fernandes,M. Margardia Diogo,Joaquim M.S. Cabral
Publisher : Elsevier
Page : 236 pages
File Size : 41,8 Mb
Release : 2013-11-15
Category : Science
ISBN : 9781908818300

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Stem Cell Bioprocessing by Tiago G. Fernandes,M. Margardia Diogo,Joaquim M.S. Cabral Pdf

Stem cell bioprocessing describes the main large-scale bioprocessing strategies for both stem cell culture and purification, envisaging the application of these cells for regenerative medicine and drug screening. Bioreactor configurations are described, including their applications for stem cell expansion, and stem cell separation techniques such as isolation and purification are discussed. Basic definitions are provided concerning the different types of stem cells, from adult stem cells to the more recent induced pluripotent stem cells. The main characteristics of these different stem cell types are described, alongside the molecular mechanisms underlying their self-renewal and differentiation. The book also focuses on methodologies currently used for in vitro stem cell culture under static conditions, including the challenge of xeno-free culture conditions, as well as culture parameters that influence stem cell culture. Approaches for both stem cell culture and separation in micro-scale conditions are presented, including the use of cellular microarrays for high-throughput screening of the effect of both soluble and extracellular matrix molecules. A further section is dedicated to application of stem cells for regenerative medicine. Maintains a unique focus on both the basic stem cell biology concepts, and their translation to large-scale bioprocessing approaches Envisages the use of stem cells in regenerative medicine and drug screening applications Discusses the application of microscale techniques as a tool to perform basic stem cell biology studies