The Annotated Hodgkin And Huxley

The Annotated Hodgkin And Huxley Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of The Annotated Hodgkin And Huxley book. This book definitely worth reading, it is an incredibly well-written.

The Annotated Hodgkin and Huxley

Indira M. Raman,David L. Ferster
The Annotated Hodgkin and Huxley Book PDF

Author : Indira M. Raman,David L. Ferster
Publisher : Princeton University Press
Page : 328 pages
File Size : 48,6 Mb
Release : 2022-01-11
Category : Science
ISBN : 9780691220659

Get Book

The Annotated Hodgkin and Huxley by Indira M. Raman,David L. Ferster Pdf

The first annotated edition of the scientific papers that created the foundation of modern neuroscience and physiology The origin of everything known about how neurons and muscles generate electrical signals can be traced back to five revolutionary papers, published in the Journal of Physiology in 1952 by Alan Hodgkin and Andrew Huxley. The principles they revealed remain cornerstones of the discipline, summarized in every introductory neuroscience and physiology course. Since that era, however, scientific practice, technology, and presentation have changed extensively. It is difficult for the modern reader to appreciate Hodgkin and Huxley’s rigorous scientific thought, elegant experimental design, ingenious analysis, and beautiful writing. This book provides the first annotated edition of these papers, offering essential background on everything, from terminology, equations, and electronics, to the greater historical and scientific context surrounding the work. The original journal pages are displayed opposite detailed notes explaining content, process, and background, with copies of the figures replotted according to modern conventions. Indispensable for scientists, teachers, and trainees alike, The Annotated Hodgkin and Huxley makes an essential body of knowledge—and an unparalleled approach to research—accessible to a new generation of readers. Reproduces the original articles paired with extensive annotations on facing pages Replots figures with modern conventions of data display Explains the development of the voltage clamp and the discovery of ionic currents and action potential generation, foundational to the study of neuroscience and physiology Summarizes the history of electrophysiology leading to Hodgkin and Huxley’s work Includes appendices on relevant concepts from mathematics, physics, electronics, chemical kinetics, and numerical methods

Metrics at Work

Angèle Christin
Metrics at Work Book PDF

Author : Angèle Christin
Publisher : Princeton University Press
Page : 268 pages
File Size : 54,8 Mb
Release : 2020-06-30
Category : Social Science
ISBN : 9780691200002

Get Book

Metrics at Work by Angèle Christin Pdf

The starkly different ways that American and French online news companies respond to audience analytics and what this means for the future of news When the news moved online, journalists suddenly learned what their audiences actually liked, through algorithmic technologies that scrutinize web traffic and activity. Has this advent of audience metrics changed journalists’ work practices and professional identities? In Metrics at Work, Angèle Christin documents the ways that journalists grapple with audience data in the form of clicks, and analyzes how new forms of clickbait journalism travel across national borders. Drawing on four years of fieldwork in web newsrooms in the United States and France, including more than one hundred interviews with journalists, Christin reveals many similarities among the media groups examined—their editorial goals, technological tools, and even office furniture. Yet she uncovers crucial and paradoxical differences in how American and French journalists understand audience analytics and how these affect the news produced in each country. American journalists routinely disregard traffic numbers and primarily rely on the opinion of their peers to define journalistic quality. Meanwhile, French journalists fixate on internet traffic and view these numbers as a sign of their resonance in the public sphere. Christin offers cultural and historical explanations for these disparities, arguing that distinct journalistic traditions structure how journalists make sense of digital measurements in the two countries. Contrary to the popular belief that analytics and algorithms are globally homogenizing forces, Metrics at Work shows that computational technologies can have surprisingly divergent ramifications for work and organizations worldwide.

John Stuart Mill's Deliberative Landscape (Routledge Revivals)

Candace A. Vogler
John Stuart Mill s Deliberative Landscape Routledge Revivals Book PDF

Author : Candace A. Vogler
Publisher : Routledge
Page : 136 pages
File Size : 52,7 Mb
Release : 2016-05-05
Category : Philosophy
ISBN : 9781317206163

Get Book

John Stuart Mill's Deliberative Landscape (Routledge Revivals) by Candace A. Vogler Pdf

First published in 2001, this book sets out to shed light on traditional controversies in Mill scholarship, underscore the significance of the contribution Mill made to associationist psychology, argue he is not entirely successful in explaining why art matters, and that this failure is linked to a deep tension in his mature work — rooted in his unwillingness to shake off the moral psychology he was raised on. The book examines various episodes and tensions in Mill’s life and work and how they relate to and informed his philosophy — while also giving a critical account of it. This book will be of interest to students of philosophy.

Case Studies in Neural Data Analysis

Mark A. Kramer,Uri T. Eden
Case Studies in Neural Data Analysis Book PDF

Author : Mark A. Kramer,Uri T. Eden
Publisher : MIT Press
Page : 385 pages
File Size : 52,5 Mb
Release : 2016-11-04
Category : Science
ISBN : 9780262529372

Get Book

Case Studies in Neural Data Analysis by Mark A. Kramer,Uri T. Eden Pdf

A practical guide to neural data analysis techniques that presents sample datasets and hands-on methods for analyzing the data. As neural data becomes increasingly complex, neuroscientists now require skills in computer programming, statistics, and data analysis. This book teaches practical neural data analysis techniques by presenting example datasets and developing techniques and tools for analyzing them. Each chapter begins with a specific example of neural data, which motivates mathematical and statistical analysis methods that are then applied to the data. This practical, hands-on approach is unique among data analysis textbooks and guides, and equips the reader with the tools necessary for real-world neural data analysis. The book begins with an introduction to MATLAB, the most common programming platform in neuroscience, which is used in the book. (Readers familiar with MATLAB can skip this chapter and might decide to focus on data type or method type.) The book goes on to cover neural field data and spike train data, spectral analysis, generalized linear models, coherence, and cross-frequency coupling. Each chapter offers a stand-alone case study that can be used separately as part of a targeted investigation. The book includes some mathematical discussion but does not focus on mathematical or statistical theory, emphasizing the practical instead. References are included for readers who want to explore the theoretical more deeply. The data and accompanying MATLAB code are freely available on the authors' website. The book can be used for upper-level undergraduate or graduate courses or as a professional reference. A version of this textbook with all of the examples in Python is available on the MIT Press website.

Spiking Neuron Models

Wulfram Gerstner,Werner M. Kistler
Spiking Neuron Models Book PDF

Author : Wulfram Gerstner,Werner M. Kistler
Publisher : Cambridge University Press
Page : 498 pages
File Size : 48,8 Mb
Release : 2002-08-15
Category : Computers
ISBN : 0521890799

Get Book

Spiking Neuron Models by Wulfram Gerstner,Werner M. Kistler Pdf

Neurons in the brain communicate by short electrical pulses, the so-called action potentials or spikes. How can we understand the process of spike generation? How can we understand information transmission by neurons? What happens if thousands of neurons are coupled together in a seemingly random network? How does the network connectivity determine the activity patterns? And, vice versa, how does the spike activity influence the connectivity pattern? These questions are addressed in this 2002 introduction to spiking neurons aimed at those taking courses in computational neuroscience, theoretical biology, biophysics, or neural networks. The approach will suit students of physics, mathematics, or computer science; it will also be useful for biologists who are interested in mathematical modelling. The text is enhanced by many worked examples and illustrations. There are no mathematical prerequisites beyond what the audience would meet as undergraduates: more advanced techniques are introduced in an elementary, concrete fashion when needed.

Image Processing Using Pulse-Coupled Neural Networks

Thomas Lindblad,Jason Kinser
Image Processing Using Pulse Coupled Neural Networks Book PDF

Author : Thomas Lindblad,Jason Kinser
Publisher : Springer Science & Business Media
Page : 184 pages
File Size : 49,7 Mb
Release : 2005-08-02
Category : Technology & Engineering
ISBN : 354024218X

Get Book

Image Processing Using Pulse-Coupled Neural Networks by Thomas Lindblad,Jason Kinser Pdf

* Weitere Angaben Verfasser: Thomas Lindblad is a professor at the Royal Institute of Technology (Physics) in Stockholm. Working and teaching nuclear and environmental physics his main interest is with sensors, signal processing and intelligent data analysis of torrent data from experiments on-line accelerators, in space, etc. Jason Kinser is an associate professor at George Mason University. He has developed a plethora of image processing applications in the medical, military, and industrial fields. He has been responsible for the conversion of PCNN theory into practical applications providing many improvements in both speed and performance

A History of the Brain

Andrew P. Wickens
A History of the Brain Book PDF

Author : Andrew P. Wickens
Publisher : Psychology Press
Page : 405 pages
File Size : 53,7 Mb
Release : 2014-12-08
Category : Psychology
ISBN : 9781317744832

Get Book

A History of the Brain by Andrew P. Wickens Pdf

A History of the Brain tells the full story of neuroscience, from antiquity to the present day. It describes how we have come to understand the biological nature of the brain, beginning in prehistoric times, and progressing to the twentieth century with the development of Modern Neuroscience. This is the first time a history of the brain has been written in a narrative way, emphasizing how our understanding of the brain and nervous system has developed over time, with the development of the disciplines of anatomy, pharmacology, physiology, psychology and neurosurgery. The book covers: beliefs about the brain in ancient Egypt, Greece and Rome the Medieval period, Renaissance and Enlightenment the nineteenth century the most important advances in the twentieth century and future directions in neuroscience. The discoveries leading to the development of modern neuroscience gave rise to one of the most exciting and fascinating stories in the whole of science. Written for readers with no prior knowledge of the brain or history, the book will delight students, and will also be of great interest to researchers and lecturers with an interest in understanding how we have arrived at our present knowledge of the brain.

The Spike

Mark Humphries
The Spike Book PDF

Author : Mark Humphries
Publisher : Princeton University Press
Page : 232 pages
File Size : 42,5 Mb
Release : 2023-01-24
Category : Psychology
ISBN : 9780691241487

Get Book

The Spike by Mark Humphries Pdf

The story of a neural impulse and what it reveals about how our brains work We see the last cookie in the box and think, can I take that? We reach a hand out. In the 2.1 seconds that this impulse travels through our brain, billions of neurons communicate with one another, sending blips of voltage through our sensory and motor regions. Neuroscientists call these blips “spikes.” Spikes enable us to do everything: talk, eat, run, see, plan, and decide. In The Spike, Mark Humphries takes readers on the epic journey of a spike through a single, brief reaction. In vivid language, Humphries tells the story of what happens in our brain, what we know about spikes, and what we still have left to understand about them. Drawing on decades of research in neuroscience, Humphries explores how spikes are born, how they are transmitted, and how they lead us to action. He dives into previously unanswered mysteries: Why are most neurons silent? What causes neurons to fire spikes spontaneously, without input from other neurons or the outside world? Why do most spikes fail to reach any destination? Humphries presents a new vision of the brain, one where fundamental computations are carried out by spontaneous spikes that predict what will happen in the world, helping us to perceive, decide, and react quickly enough for our survival. Traversing neuroscience’s expansive terrain, The Spike follows a single electrical response to illuminate how our extraordinary brains work.

Modeling and Simulating Cardiac Electrical Activity

David J. Christini,Trine Krogh-Madsen
Modeling and Simulating Cardiac Electrical Activity Book PDF

Author : David J. Christini,Trine Krogh-Madsen
Publisher : Unknown
Page : 0 pages
File Size : 55,8 Mb
Release : 2020
Category : Electrocardiography
ISBN : 0750320648

Get Book

Modeling and Simulating Cardiac Electrical Activity by David J. Christini,Trine Krogh-Madsen Pdf

This book provides a thorough introduction to the topic of mathematical modeling of electrical activity in the heart, from molecular details of ionic channel dynamics to clinically derived patient-specific models. It discusses how cellular ionic models are formulated, introduces commonly used models and explains why there are so many different models available. The chapters cover modeling of the intracellular calcium handling that underlies cellular contraction as well as modeling molecular-level details of cardiac ion channels, and also focus on specialized topics such as cardiomyocyte energetics and signalling pathways. It is an excellent resource for experienced and specialised researchers in the field, but also biological scientists with a limited background in mathematical modelling and computational methods. Part of Biophysical Society-IOP series.

Nonlinear Dynamics in Complex Systems

Armin Fuchs
Nonlinear Dynamics in Complex Systems Book PDF

Author : Armin Fuchs
Publisher : Springer Science & Business Media
Page : 237 pages
File Size : 53,9 Mb
Release : 2012-09-22
Category : Technology & Engineering
ISBN : 9783642335525

Get Book

Nonlinear Dynamics in Complex Systems by Armin Fuchs Pdf

With many areas of science reaching across their boundaries and becoming more and more interdisciplinary, students and researchers in these fields are confronted with techniques and tools not covered by their particular education. Especially in the life- and neurosciences quantitative models based on nonlinear dynamics and complex systems are becoming as frequently implemented as traditional statistical analysis. Unfamiliarity with the terminology and rigorous mathematics may discourage many scientists to adopt these methods for their own work, even though such reluctance in most cases is not justified. This book bridges this gap by introducing the procedures and methods used for analyzing nonlinear dynamical systems. In Part I, the concepts of fixed points, phase space, stability and transitions, among others, are discussed in great detail and implemented on the basis of example elementary systems. Part II is devoted to specific, non-trivial applications: coordination of human limb movement (Haken-Kelso-Bunz model), self-organization and pattern formation in complex systems (Synergetics), and models of dynamical properties of neurons (Hodgkin-Huxley, Fitzhugh-Nagumo and Hindmarsh-Rose). Part III may serve as a refresher and companion of some mathematical basics that have been forgotten or were not covered in basic math courses. Finally, the appendix contains an explicit derivation and basic numerical methods together with some programming examples as well as solutions to the exercises provided at the end of certain chapters. Throughout this book all derivations are as detailed and explicit as possible, and everybody with some knowledge of calculus should be able to extract meaningful guidance follow and apply the methods of nonlinear dynamics to their own work. “This book is a masterful treatment, one might even say a gift, to the interdisciplinary scientist of the future.” “With the authoritative voice of a genuine practitioner, Fuchs is a master teacher of how to handle complex dynamical systems.” “What I find beautiful in this book is its clarity, the clear definition of terms, every step explained simply and systematically.” (J.A.Scott Kelso, excerpts from the foreword)

The NEURON Book

Nicholas T. Carnevale,Michael L. Hines
The NEURON Book Book PDF

Author : Nicholas T. Carnevale,Michael L. Hines
Publisher : Cambridge University Press
Page : 399 pages
File Size : 44,8 Mb
Release : 2006-01-12
Category : Medical
ISBN : 9781139447836

Get Book

The NEURON Book by Nicholas T. Carnevale,Michael L. Hines Pdf

The authoritative reference on NEURON, the simulation environment for modeling biological neurons and neural networks that enjoys wide use in the experimental and computational neuroscience communities. This book shows how to use NEURON to construct and apply empirically based models. Written primarily for neuroscience investigators, teachers, and students, it assumes no previous knowledge of computer programming or numerical methods. Readers with a background in the physical sciences or mathematics, who have some knowledge about brain cells and circuits and are interested in computational modeling, will also find it helpful. The NEURON Book covers material that ranges from the inner workings of this program, to practical considerations involved in specifying the anatomical and biophysical properties that are to be represented in models. It uses a problem-solving approach, with many working examples that readers can try for themselves.

Fundamentals of Computational Neuroscience

Thomas Trappenberg
Fundamentals of Computational Neuroscience Book PDF

Author : Thomas Trappenberg
Publisher : Oxford University Press
Page : 417 pages
File Size : 49,9 Mb
Release : 2010
Category : Mathematics
ISBN : 9780199568413

Get Book

Fundamentals of Computational Neuroscience by Thomas Trappenberg Pdf

The new edition of Fundamentals of Computational Neuroscience build on the success and strengths of the first edition. Completely redesigned and revised, it introduces the theoretical foundations of neuroscience with a focus on the nature of information processing in the brain.

Hard to Break

Russell A. Poldrack
Hard to Break Book PDF

Author : Russell A. Poldrack
Publisher : Princeton University Press
Page : 230 pages
File Size : 46,5 Mb
Release : 2021-05-04
Category : Psychology
ISBN : 9780691194325

Get Book

Hard to Break by Russell A. Poldrack Pdf

"Well-publicized research in psychology tells us that over half of our attempts to change habitual behavior fail within one year. Even without reading the research, most of us will intuitively sense the truth in this, as we have all tried and failed to rid ourselves of one bad habit or another. The human story of habits and the difficulty of change has been told in many books--most of which will make only a quick reference to dopamine or the 'lizard brain' before moving on to practical tips and tricks for behavior change. In contrast, [this book] will tell the brain's story about why behavior is so hard to change"--

Mathematical Analysis of Evolution, Information, and Complexity

Wolfgang Arendt,Wolfgang P. Schleich
Mathematical Analysis of Evolution Information and Complexity Book PDF

Author : Wolfgang Arendt,Wolfgang P. Schleich
Publisher : John Wiley & Sons
Page : 502 pages
File Size : 45,6 Mb
Release : 2009-07-10
Category : Science
ISBN : 9783527628032

Get Book

Mathematical Analysis of Evolution, Information, and Complexity by Wolfgang Arendt,Wolfgang P. Schleich Pdf

Mathematical Analysis of Evolution, Information, and Complexity deals with the analysis of evolution, information and complexity. The time evolution of systems or processes is a central question in science, this text covers a broad range of problems including diffusion processes, neuronal networks, quantum theory and cosmology. Bringing together a wide collection of research in mathematics, information theory, physics and other scientific and technical areas, this new title offers elementary and thus easily accessible introductions to the various fields of research addressed in the book.

The Annotated and Illustrated Double Helix

James D. Watson,Alexander Gann,Jan Witkowski
The Annotated and Illustrated Double Helix Book PDF

Author : James D. Watson,Alexander Gann,Jan Witkowski
Publisher : Simon and Schuster
Page : 361 pages
File Size : 52,5 Mb
Release : 2012-11-06
Category : Science
ISBN : 9781476715513

Get Book

The Annotated and Illustrated Double Helix by James D. Watson,Alexander Gann,Jan Witkowski Pdf

On the fiftieth anniversary of Watson and Crick receiving the Nobel Prize, a freshly annotated and illustrated edition of The Double Helix provides new insights into a scientific revolution. Published to mark the fiftieth anniversary of the Nobel Prize for Watson and Crick’s discovery of the structure of DNA, an annotated and illustrated edition of this classic book gives new insights into the personal relationships between James Watson, Frances Crick, Maurice Wilkins, and Rosalind Franklin, and the making of a scientific revolution.