Modeling And Simulating Cardiac Electrical Activity

Author : Trine Krogh-Madsen,David J. Christini
Publisher : IOP Publishing Limited
Page : 236 pages
File Size : 55,7 Mb
Release : 2020-12-03
Category : Science
ISBN : 0750320621

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Modeling and Simulating Cardiac Electrical Activity by Trine Krogh-Madsen,David J. Christini Pdf

This book provides a thorough introduction to the topic of mathematical modeling of electrical activity in the heart, from molecular details of ionic channel dynamics to clinically derived patient-specific models. It discusses how cellular ionic models are formulated, introduces commonly used models and explains why there are so many different models available. The chapters cover modeling of the intracellular calcium handling that underlies cellular contraction as well as modeling molecular-level details of cardiac ion channels, and specialized topics such as cardiomyocyte energetics and signalling pathways. It is an excellent resource for experienced and specialized researchers in the field, but also biological scientists with a limited background in mathematical modelling and computational methods. Key Features Thorough introduction to the topic of mathematical modeling of electrical activity in the heart Focuses on use of experimental data in mathematical modeling, and on explanations rather than equations In addition to being experts in the field, the contributing authors are expert science communicators

Author : Trine Krogh-Madsen
Publisher : Myprint
Page : 236 pages
File Size : 46,5 Mb
Release : 2020-12-03
Category : Electronic
ISBN : 0750320656

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Modeling and Simulating Cardiac Electrical Activity by Trine Krogh-Madsen Pdf

This book provides a thorough introduction to the topic of mathematical modeling of electrical activity in the heart, from molecular details of ionic channel dynamics to clinically derived patient-specific models. It discusses how cellular ionic models are formulated, introduces commonly used models and explains why there are so many different models available. The chapters cover modeling of the intracellular calcium handling that underlies cellular contraction as well as modeling molecular-level details of cardiac ion channels, and specialized topics such as cardiomyocyte energetics and signalling pathways. It is an excellent resource for experienced and specialized researchers in the field, but also biological scientists with a limited background in mathematical modelling and computational methods. Key Features Thorough introduction to the topic of mathematical modeling of electrical activity in the heart Focuses on use of experimental data in mathematical modeling, and on explanations rather than equations In addition to being experts in the field, the contributing authors are expert science communicators

Author : Andrew J. Pullan,Leo K. Cheng,Martin L. Buist
Publisher : World Scientific
Page : 446 pages
File Size : 45,7 Mb
Release : 2005
Category : Medical
ISBN : 9789812563736

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Mathematically Modelling the Electrical Activity of the Heart by Andrew J. Pullan,Leo K. Cheng,Martin L. Buist Pdf

This book on modelling the electrical activity of the heart is an attempt to describe continuum based modelling of cardiac electrical activity from the cell level to the body surface (the forward problem), and back again (the inverse problem). Background anatomy and physiology is covered briefly to provide a suitable context for understanding the detailed modelling that is presented herein. The questions of what is mathematical modelling and why one would want to use mathematical modelling are addressed to give some perspective to the philosophy behind our approach. Our view of mathematical modelling is broad ? it is not simply about obtaining a solution to a set of mathematical equations, but includes some material on aspects such as experimental and clinical validation.

Author : Joakim Sundnes,Glenn Terje Lines,Xing Cai,Bjørn Frederik Nielsen,Kent-Andre Mardal,Aslak Tveito
Publisher : Springer Science & Business Media
Page : 323 pages
File Size : 51,9 Mb
Release : 2007-06-26
Category : Computers
ISBN : 9783540334378

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Computing the Electrical Activity in the Heart by Joakim Sundnes,Glenn Terje Lines,Xing Cai,Bjørn Frederik Nielsen,Kent-Andre Mardal,Aslak Tveito Pdf

This book describes mathematical models and numerical techniques for simulating the electrical activity in the heart. It gives an introduction to the most important models, followed by a detailed description of numerical techniques. Particular focus is on efficient numerical methods for large scale simulations on both scalar and parallel computers. The results presented in the book will be of particular interest to researchers in bioengineering and computational biology.

Author : Andrew Pullan
Publisher : Unknown
Page : 442 pages
File Size : 48,7 Mb
Release : 2005
Category : Electronic
ISBN : 9812775153

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Mathematically Modelling the Electrical Activity of the Heart by Andrew Pullan Pdf

Author : Nicholas Ayache,Hervé Delingette
Publisher : Springer
Page : 392 pages
File Size : 48,8 Mb
Release : 2003-08-03
Category : Computers
ISBN : 9783540450153

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Surgery Simulation and Soft Tissue Modeling by Nicholas Ayache,Hervé Delingette Pdf

This book constitutes the refereed proceedings of the International Symposium on Surgery Simulation and Soft Tissue Modeling, IS4TM 2003, held in Juan-Les-Pins, France in June 2003. The 33 revised full papers presented together with 3 invited papers were carefully reviewed and selected from 45 submissions. The papers are organized in topical sections on soft tissue models, haptic rendering, cardiac modeling, and patient specific simulators.

Author : Frank B. Sachse,Gunnar Seemann
Publisher : Springer
Page : 488 pages
File Size : 48,6 Mb
Release : 2007-07-10
Category : Computers
ISBN : 9783540729075

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Functional Imaging and Modeling of the Heart by Frank B. Sachse,Gunnar Seemann Pdf

This book constitutes the refereed proceedings of the 4th International Conference on Functional Imaging and Modeling of the Heart, FIMH 2007, held in Salt Lake City, UT, USA in June 2007. The contributions describe both experimental and computational studies and cover topics such as imaging and image analysis, cardiac electrophysiology, electro- and magnetocardiography, cardiac mechanics and clinical application, imaging and anatomical modeling.

Author : Yves Coudière,Valéry Ozenne,Edward Vigmond,Nejib Zemzemi
Publisher : Springer
Page : 435 pages
File Size : 44,5 Mb
Release : 2019-05-29
Category : Computers
ISBN : 9783030219499

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Functional Imaging and Modeling of the Heart by Yves Coudière,Valéry Ozenne,Edward Vigmond,Nejib Zemzemi Pdf

This book constitutes the refereed proceedings of the 10th International Conference on Functional Imaging and Modeling of the Heart, held in Bordeaux, France, in June 2019. The 46 revised full papers were carefully reviewed and selected from 50 submissions. The focus of the papers is on following topics: Electrophysiology: mapping and biophysical modelling; Novel imaging tools and analysis methods for myocardial tissue characterization and remodeling; Biomechanics: modeling and tissue property measurements; Advanced cardiac image analysis tools for diagnostic and interventions.

Author : Nenad Filipovic
Publisher : John Wiley & Sons
Page : 386 pages
File Size : 48,9 Mb
Release : 2021-12-14
Category : Science
ISBN : 9781119563945

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Computational Modeling and Simulation Examples in Bioengineering by Nenad Filipovic Pdf

A systematic overview of the quickly developing field of bioengineering—with state-of-the-art modeling software! Computational Modeling and Simulation Examples in Bioengineering provides a comprehensive introduction to the emerging field of bioengineering. It provides the theoretical background necessary to simulating pathological conditions in the bones, muscles, cardiovascular tissue, and cancers, as well as lung and vertigo disease. The methodological approaches used for simulations include the finite element, dissipative particle dynamics, and lattice Boltzman. The text includes access to a state-of-the-art software package for simulating the theoretical problems. In this way, the book enhances the reader's learning capabilities in the field of biomedical engineering. The aim of this book is to provide concrete examples of applied modeling in biomedical engineering. Examples in a wide range of areas equip the reader with a foundation of knowledge regarding which problems can be modeled with which numerical methods. With more practical examples and more online software support than any competing text, this book organizes the field of computational bioengineering into an accessible and thorough introduction. Computational Modeling and Simulation Examples in Bioengineering: Includes a state-of-the-art software package enabling readers to engage in hands-on modeling of the examples in the book Provides a background on continuum and discrete modeling, along with equations and derivations for three key numerical methods Considers examples in the modeling of bones, skeletal muscles, cartilage, tissue engineering, blood flow, plaque, and more Explores stent deployment modeling as well as stent design and optimization techniques Generates different examples of fracture fixation with respect to the advantages in medical practice applications Computational Modeling and Simulation Examples in Bioengineering is an excellent textbook for students of bioengineering, as well as a support for basic and clinical research. Medical doctors and other clinical professionals will also benefit from this resource and guide to the latest modeling techniques.

Author : Daniel B. Ennis,Luigi E. Perotti,Vicky Y. Wang
Publisher : Springer Nature
Page : 697 pages
File Size : 42,6 Mb
Release : 2021-06-17
Category : Computers
ISBN : 9783030787103

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Functional Imaging and Modeling of the Heart by Daniel B. Ennis,Luigi E. Perotti,Vicky Y. Wang Pdf

This book constitutes the refereed proceedings of the 11th International Conference on Functional Imaging and Modeling of the Heart, which took place online during June 21-24, 2021, organized by the University of Stanford. The 65 revised full papers were carefully reviewed and selected from 68 submissions. They were organized in topical sections as follows: advanced cardiac and cardiovascular image processing; cardiac microstructure: measures and models; novel approaches to measuring heart deformation; cardiac mechanics: measures and models; translational cardiac mechanics; modeling electrophysiology, ECG, and arrhythmia; cardiovascular flow: measures and models; and atrial microstructure, modeling, and thrombosis prediction.

Author : Bin He
Publisher : Springer Science & Business Media
Page : 332 pages
File Size : 53,6 Mb
Release : 2010-07-03
Category : Technology & Engineering
ISBN : 9780387499635

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Modeling & Imaging of Bioelectrical Activity by Bin He Pdf

Over the past several decades, much progress has been made in understanding the mechanisms of electrical activity in biological tissues and systems, and for developing non-invasive functional imaging technologies to aid clinical diagnosis of dysfunction in the human body. The book will provide full basic coverage of the fundamentals of modeling of electrical activity in various human organs, such as heart and brain. It will include details of bioelectromagnetic measurements and source imaging technologies, as well as biomedical applications. The book will review the latest trends in the field and comment on the future direction in this fast developing line of research.

Author : Jorge Henriques,Nuno Neves,Paulo de Carvalho
Publisher : Springer Nature
Page : 2067 pages
File Size : 52,6 Mb
Release : 2019-09-24
Category : Technology & Engineering
ISBN : 9783030316358

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XV Mediterranean Conference on Medical and Biological Engineering and Computing – MEDICON 2019 by Jorge Henriques,Nuno Neves,Paulo de Carvalho Pdf

This book gathers the proceedings of MEDICON 2019 – the XV Mediterranean Conference on Medical and Biological Engineering and Computing – which was held in September 26-28, 2019, in Coimbra, Portugal. A special emphasis has been given to practical findings, techniques and methods, aimed at fostering an effective patient empowerment, i.e. to position the patient at the heart of the health system and encourages them to be actively involved in managing their own healthcare needs. The book reports on research and development in electrical engineering, computing, data science and instrumentation, and on many topics at the interface between those disciplines. It provides academics and professionals with extensive knowledge on cutting-edge techniques and tools for detection, prevention, treatment and management of diseases. A special emphasis is given to effective advances, as well as new directions and challenges towards improving healthcare through holistic patient empowerment.

Author : Davide Ambrosi,Alfio Quarteroni,Gianluigi Rozza
Publisher : Springer Science & Business Media
Page : 418 pages
File Size : 46,5 Mb
Release : 2012-10-31
Category : Mathematics
ISBN : 9788847019355

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Modeling of Physiological Flows by Davide Ambrosi,Alfio Quarteroni,Gianluigi Rozza Pdf

This book offers a mathematical update of the state of the art of the research in the field of mathematical and numerical models of the circulatory system. It is structured into different chapters, written by outstanding experts in the field. Many fundamental issues are considered, such as: the mathematical representation of vascular geometries extracted from medical images, modelling blood rheology and the complex multilayer structure of the vascular tissue, and its possible pathologies, the mechanical and chemical interaction between blood and vascular walls, and the different scales coupling local and systemic dynamics. All of these topics introduce challenging mathematical and numerical problems, demanding for advanced analysis and efficient simulation techniques, and pay constant attention to applications of relevant clinical interest. This book is addressed to graduate students and researchers in the field of bioengineering, applied mathematics and medicine, wishing to engage themselves in the fascinating task of modeling the cardiovascular system or, more broadly, physiological flows.

Author : Hans Petter Langtangen,Aslak Tveito
Publisher : Springer Science & Business Media
Page : 676 pages
File Size : 55,6 Mb
Release : 2012-09-22
Category : Mathematics
ISBN : 9783642182372

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Advanced Topics in Computational Partial Differential Equations by Hans Petter Langtangen,Aslak Tveito Pdf

A gentle introduction to advanced topics such as parallel computing, multigrid methods, and special methods for systems of PDEs. The goal of all chapters is to ‘compute’ solutions to problems, hence algorithmic and software issues play a central role. All software examples use the Diffpack programming environment - some experience with Diffpack is required. There are also some chapters covering complete applications, i.e., the way from a model, expressed as systems of PDEs, through to discretization methods, algorithms, software design, verification, and computational examples. Suitable for readers with a background in basic finite element and finite difference methods for partial differential equations.

Author : Gregory R. Bock,Jamie A. Goode
Publisher : John Wiley & Sons
Page : 270 pages
File Size : 45,7 Mb
Release : 2003-07-07
Category : Science
ISBN : 9780470857908

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'In Silico' Simulation of Biological Processes by Gregory R. Bock,Jamie A. Goode Pdf

Over recent decades vast amounts of biological data have been accumulated. However, it is becoming increasingly difficult to apply traditional theoretical methods to the formulation of coherent pictures of cell and organ function because it is no longer possible for a human theorist to integrate all of the available information. Instead, computer technologies must now be used to perform this integration. This book brings together contributions from many different fields to summarize the current status of computer-assisted modelling of biological processes. The initial chapters deal with fundamental developments in hardware, software and mathematics that underlie current approaches to biological modelling. Next, different approaches to collating data on gene structure and function are presented. These databases form a vital resource for any investigator trying to construct an integrated picture of particular biological systems. Cell signalling systems form a particularly complicated aspect of all cellular function and are important both in the understanding of basic cellular processes and in selecting targets for drugs. Recent approaches to integrating data on cell signalling into computer models are covered. Further chapters build on these approaches to show how computerized models of intact cells can be developed. Finally, approaches to the computer modelling of whole organs such as the heart are presented. The role of computer modelling in drug design is the subject of the final chapter and is also touched on throughout the discussions.