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Author : Seymour Reichlin,Ross J. Baldessarini,Joseph B. Martin
Publisher : Unknown
Page : 514 pages
File Size : 41,6 Mb
Release : 1978
Category : Science
ISBN : UOM:39015001636953
Author : Giuseppe Nistico,Umberto Scapagnini
Publisher : Elsevier
Page : 448 pages
File Size : 53,7 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323149921
Neurotransmitters and Anterior Pituitary Function discusses research findings on neurotransmitter-neurohormone interactions in the control of the anterior pituitary. This book contains five chapters that specifically tackle the most salient constituents of the neural-endocrine communication system in mammals. This book deals first with the biochemistry, physiology, and pharmacology of proved or putative neurotransmitters, as well as some of the techniques used for determining their synthesis or turnover in the central nervous system (CNS) of experimental animals or in man. These topics are followed by a discussion on the principal functions of the most well-known neurotransmitter containing neurons based on sophisticated techniques for neurotransmitter measurements. A chapter highlights both traditional and a vast series of developed drugs that affect both neurotransmitter and neuroendocrine function. Discussions then shift to the experimental evidence on pituitary function control by the brain through releasing and inhibiting hormones secreted by hypothalamic neuroendocrine cells; the chemical isolation, identification, and synthesis of hypothalamic neurohormones; and concepts of their mechanism of action at the level of the pituitary cells. This text further explores the role of specific brain neurotransmitters in controlling pituitary hormone secretions in both experimental animals and in man and the possible CNS site(s) where neurotransmitters and neurohormones interact for the control of anterior pituitary secretion. The concluding chapter describes the actual or potential application of neuropharmacologic approaches to the diagnosis of and therapy for specific disorders of neuroendocrine function. Clinical neuroendocrinologists and researchers and students in neuroendocrinology, neurobiology, neuropharmacology, neurophysiology, and psychiatry will find this book invaluable.
Author : Gabriel Zada,M. Beatriz S. Lopes,Srinivasan Mukundan Jr.,Edward R. Laws Jr.
Publisher : Springer
Page : 546 pages
File Size : 47,9 Mb
Release : 2015-10-27
Category : Medical
ISBN : 9783319228556
This book presents, in a stepwise and interactive fashion, approximately 75 cases that reflect the wide spectrum of pathology encountered in this region. Each case description commences with a concise clinical scenario. High-quality radiologic, laboratory, and histopathologic images depicting the differentiating features of the lesion subtype in question are then presented, and key operative and clinical management pearls are briefly reviewed. The interdisciplinary nature of this easy-to-use color atlas and textbook reflects the fact that the management of patients with sellar and parasellar lesions is itself often interdisciplinary. The format is unique in that no similar interdisciplinary book is available on lesions of this region of the brain. Atlas of Sellar and Parasellar Lesions: Clinical, Imaging, and Pathologic Correlations is of great value for practitioners and trainees in a range of medical specialties, including radiology, neurology, endocriniology, pathology, oncology, radiation oncology, and neurosurgery.
Author : J. Gordon Betts,Peter DeSaix,Jody E. Johnson,Oksana Korol,Dean H. Kruse,Brandon Poe,James A. Wise,Mark Womble,Kelly A. Young
Publisher : Unknown
Page : 0 pages
File Size : 40,7 Mb
Release : 2013-04-25
Category : Electronic
ISBN : 1947172808
Author : Constantine A. Stratakis
Publisher : Academic Press
Page : 312 pages
File Size : 51,6 Mb
Release : 2021-06-01
Category : Medical
ISBN : 9780128145388
Gigantism and Acromegaly brings together pituitary experts, taking readers from bench research, to genetic analysis, clinical analysis, and new therapeutic approaches. This book serves as a reference for growth hormone over-secretion and its diagnosis and treatment for endocrinologists, pediatricians, internists, and neurosurgeons, and for geneticists. Pharmaceutical companies may use it as a reference for drug development and research. Students, residents and fellows in medicine and endocrinology and genetics will also find it valuable as it provides a single up-to-date review of the molecular biology of gigantism and acromegaly as well as recommended approaches to evaluation and management. Acromegaly is a rare pituitary disorder that slowly changes its adult victim’s appearance over time: larger hands and feet, bigger jaw, forehead, nose, and lips. Generally, a benign pituitary tumor is the cause and symptoms of acromegaly can vary from patient to patient, making a diagnosis difficult and prolonging suffering for years. Early detection is key in the management of acromegaly as the pathologic effects of increased growth hormone (GH) production are progressive and can be life-threatening as the result of associated cardiovascular, cerebrovascular, and respiratory disorders and malignancies. Accessible, up-to-date overview of the characteristics, state-of-the-art diagnostic procedures, and management of acromegaly and gigantism Provides a unique compendium of endocrinology, genetics, clinical diagnosis and therapeutics Contains contributions from internationally known experts who have treated patients with acromegaly and gigantism
Author : A. Tixier-Vidal,Marilyn G. Farquhar
Publisher : Elsevier
Page : 300 pages
File Size : 49,8 Mb
Release : 2013-09-03
Category : Science
ISBN : 9781483273945
Ultrastructure in Biological Systems, Volume 7: The Anterior Pituitary presents the mechanisms involved in the release of adenohypophysial hormones. This book explores the morphological approach to fundamental aspects of pituitary cell biology. Organized into eight chapters, this book begins with an overview of how the ultrastructure of cellular organelles can yield valid criteria of identification. This text then discusses the cellular and subcellular localization of anterior pituitary hormones by immunoelectron microscopy. Other chapters consider the localization of possible receptor sites for hormonal messengers on anterior pituitary cells. This book discusses as well the in vitro systems that have undergone a significant development, which is the ultrastructure and function of dispersed anterior pituitary cells. The final chapter deals with the ultrastructure of pituitary tumors, which can be divided into two categories, namely, functional and nonfunctional, according to the presence or the absence in the host of hormonal hypersecretion signs. This book is a valuable resource for biochemists, endocrinologists, histologists, and pathologists.
Author : T.C. Jones,U. Mohr,R.D. Hunt
Publisher : Springer Science & Business Media
Page : 373 pages
File Size : 44,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642967207
The International Life Sciences Institute (ILSI) was creat ed to promote cooperative efforts toward solving critical health and safety questions involving foods, drugs, cosmet ics, chemicals, and other aspects of the environment. The officers and trustees believe that questions regarding health and safety are best resolved when government and industry rely on scientific investigations, analyses, and reviews by independent experts. Further, the scientific aspects of an issue should be examined and discussed on an international basis, separate from the political concerns of individual companies. The Institute is pleased to sponsor this set of monographs on pathology of laboratory animals. This project will help to improve the scientific application of the techniques of pathology to the evaluation of substances in our environ ment. The worldwide distribution of the authors, editors, and editorial board encourages the expectation that inter national communication and cooperation will also be strengthened. Alex Malaspina President International Life Sciences Institute Preface This book on the endocrine system is Volume I of a set of reference books on pathology of laboratory animals, prepared by the Interna tional Life Sciences Institute in response to recommendations from its Committee on Pathology and Toxicology. One aim is to provide infor mation which will be useful to pathologists, especially those involved in studies on the safety of foods, drugs, chemicals, and other sub stances in the environment.
Author : Shlomo Melmed
Publisher : Academic Press
Page : 744 pages
File Size : 53,6 Mb
Release : 2010-12-09
Category : Medical
ISBN : 0123809274
The pituitary, albeit a small gland, is known as the "master gland" of the endocrine system and contributes to a wide spectrum of disorders, diseases, and syndromes. Since the publication of the second edition of The Pituitary, in 2002, there have been major advances in the molecular biology research of pituitary hormone production and action and there is now a better understanding of the pathogenesis of pituitary tumors and clinical syndromes resulting in perturbation of pituitary function. There have also been major advances in the clinical management of pituitary disorders. Medical researchers and practitioners now better understand the morbidity and mortality associated with pituitary hormone hyposecretion and hypersecretion. Newly developed drugs, and improved methods of delivering established drugs, are allowing better medical management of acromegaly and prolactinoma. These developments have improved the worldwide consensus around the definition of a "cure" for pituitary disease, especially hormone hypersecretion, and hence will improve the success or lack of success of various forms of therapy. It is therefore time for a new edition of The Pituitary. The third edition will continue to be divided into sections that summarize normal hypothalamic-pituitary development and function, hypothalamic-pituitary failure, and pituitary tumors; additional sections will describe pituitary disease in systemic disorders and diagnostic procedures, including imaging, assessment of the eyes, and biochemical testing. The first chapter will be completely new – placing a much greater emphasis on physiology and pathogenesis. Two new chapters will be added on the Radiation and Non-surgical Management of the Pituitary and Other Pituitary Lesions. Other chapters will be completely updated and many new author teams will be invited. The second edition published in 2002 and there have been incredible changes in both the research and clinical aspects of the pituitary over the past 8 years – from new advances in growth hormones to pituitary tumor therapy. Presents a comprehensive, translational source of information about the pituitary in one reference work Pituitary experts (from all areas of research and practice) take readers from the bench research (cellular and molecular mechanism), through genomic and proteomic analysis, all the way to clinical analysis (histopathology and imaging) and new therapeutic approaches Clear presentation by endocrine researchers of the cellular and molecular mechanisms underlying pituitary hormones and growth factors as well as new techniques used in detecting lesions (within the organ) and other systemic disorders Clear presentation by endocrinologists and neuroendocrine surgeons of how imaging, assessment of the eyes, and biochemical testing can lead to new therapeutic approaches
Author : Patricia E. Molina
Publisher : McGraw Hill Professional
Page : 307 pages
File Size : 41,6 Mb
Release : 2010-07-13
Category : Medical
ISBN : 9780071491174
Market: First Year Medical students, Nurse Practitioner students, and Physician Assistant students Topics covered will be tested on USMLE Step I Each chapter includes self-study questions, learning objectives, and clinical examples Two important areas have been updated: the first pertains to hormonal regulation of bone metabolism and the second to hormonal aspects of obesity and metabolic syndrome
Author : Ajay S. Bhatnagar
Publisher : Unknown
Page : 478 pages
File Size : 51,9 Mb
Release : 1983
Category : Adenohypophysis
ISBN : UOM:39015004443365
Author : G. W. Harris,B. T. Donovan
Publisher : Univ of California Press
Page : 1036 pages
File Size : 41,6 Mb
Release : 2023-12-22
Category : Medical
ISBN : 9780520309364
This title is part of UC Press's Voices Revived program, which commemorates University of California Press’s mission to seek out and cultivate the brightest minds and give them voice, reach, and impact. Drawing on a backlist dating to 1893, Voices Revived makes high-quality, peer-reviewed scholarship accessible once again using print-on-demand technology. This title was originally published in 1966.
Author : Ajay S. Bhatnagar
Publisher : Unknown
Page : 471 pages
File Size : 46,8 Mb
Release : 1983-01-01
Category : Electronic
ISBN : 0783795238
Author : David Chambers,Christopher Huang,Gareth Matthews
Publisher : Cambridge University Press
Page : 469 pages
File Size : 46,9 Mb
Release : 2019-07-25
Category : Medical
ISBN : 9781108463997
Easily understood, up-to-date and clinically relevant, this book provides junior anaesthetists with an essential physiology resource.
Author : Richard E. Brown
Publisher : Cambridge University Press
Page : 434 pages
File Size : 55,5 Mb
Release : 1994-01-27
Category : Science
ISBN : 0521426650
This book is designed as an introductory text in neuroendocrinology; the study of the interaction between the brain and endocrine system and the influence of this on behaviour. The endocrine glands, pituitary gland and hypothalamus and their interactions and hormones are discussed. The action of steroid and thyroid hormone receptors and the regulation of target cell response to hormones is examined. The function of neuropeptides is discussed with respect to the neuroendocrine system and behaviour. The neuroimmune system and lymphokines are described and the interaction between the neuroendocrine and neuroimmune systems discussed. Finally, methods for studying hormonal influences on behaviour are outlined. Each chapter has review and essay questions designed for advanced students and honours or graduate students with a background in neuroscience, respectively.
Author : Anders Juul,Jens O. L. Jorgensen
Publisher : Cambridge University Press
Page : 536 pages
File Size : 41,9 Mb
Release : 2000-04-27
Category : Medical
ISBN : 0521641888
This revised new edition reviews the substantial advances in our understanding of the vital role of growth hormone (GH) in maintaining adult health, and the resulting disorders from GH deficiency. The first edition, published in 1996, provided a pioneering overview of the subject; this new edition provides an even more comprehensive account, fully updated with the latest research, clinical applications, and references. The therapeutic benefits of GH treatment in GH deficiency are thoroughly evaluated, including effects on metabolism, cardiac function, exercise performance, psychosocial aspects, and aging and gender-specific effects. This compilation by the world's leading experts covers clinical investigation, diagnosis and treatment issues, and encompasses new knowledge of the control and action of GH secretion. This volume is the most authoritative, comprehensive, and detailed account available and will be an essential source of reference for all endocrinologists.