The Biology Of Plasmids

Author : David Summers
Publisher : John Wiley & Sons
Page : 169 pages
File Size : 53,6 Mb
Release : 2009-07-17
Category : Science
ISBN : 9781444313734

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The Biology of Plasmids by David Summers Pdf

Plasmids are closed, circular pieces of DNA that are able to self-replicate and are carried by many bacteria. They provide unique functions for bacteria by allowing them to sexually replicate and to pass on genetic material between each other. Plasmids are also responsible for the genetic factors that give resistance to antibiotics, and provide the enzymes needed to break down poorly metabolised food resources. The author has provided an updated treatment of the structure, function and application of plasmids suitable for undergraduates and medical students. Employing an original teaching perspective--examining plasmids as living organisms with either a symbiotic or parasitic mode of survival--this text provides an important framework for understanding the structure and function of plasmids in an evolutionary context. The most up to date text on plasmids An innovative teaching perspective makes for easy student understanding Contains crucial chapters on the importance of plasmids for clinical and biological research

Author : Munazza Gull
Publisher : BoD – Books on Demand
Page : 72 pages
File Size : 41,7 Mb
Release : 2019-06-19
Category : Medical
ISBN : 9781838802370

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Plasmid by Munazza Gull Pdf

This book captures in a single volume the wealth of information on the plasmid structure, function, and biology of all organisms that have been examined to date. Plasmids exhibit wide variations in size, modes of replication and transmission, host ranges, and the genes they carry and have provided us with a great understanding of basic life principles at the molecular level. Written by experts in the field, this book is a valuable source of up-to-date information, delivering the latest impacts on studies in the areas of plasmid types, genomes, purification analysis, and expression of recombinant proteins in bacteria. Plasmid utilization in the synthesis of plasmid-based vaccines, plasmids as genetic tools, and their applications in ecology and the evolutionary process are also covered. This book is a single source of valuable information for instructors and students in advanced undergraduate and graduate courses on plasmids. It will also appeal to researchers seeking to find new relationships between biological processes that are linked by plasmids to the environment.

Author : Marcelo E. Tolmasky,Juan C. Alonso
Publisher : John Wiley & Sons
Page : 512 pages
File Size : 44,9 Mb
Release : 2020-07-24
Category : Science
ISBN : 9781555818982

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Plasmids by Marcelo E. Tolmasky,Juan C. Alonso Pdf

Explore the remarkable discoveries in the rapidly expanding field of plasmid biology Plasmids are integral to biological research as models for innumerable mechanisms of living cells, as tools for creating the most diverse therapies, and as crucial helpers for understanding the dissemination of microbial populations. Their role in virulence and antibiotic resistance, together with the generalization of "omics" disciplines, has recently ignited a new wave of interest in plasmids. This comprehensive book contains a series of expertly written chapters focused on plasmid biology, mechanistic details of plasmid function, and the increased utilization of plasmids in biotechnology and pharmacology that has occurred in the past decade. Plasmids: Biology and Impact in Biotechnology and Discovery serves as an invaluable reference for researchers in the wide range of fields and disciplines that utilize plasmids and can also be used as a textbook for upper-level undergraduate and graduate courses in biotechnology and molecular biology.

Author : Gregory Phillips,Barbara E. Funnell
Publisher : Washington, DC : ASM Press
Page : 648 pages
File Size : 49,6 Mb
Release : 2004
Category : Plasmids
ISBN : UOM:39015059165848

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Plasmid Biology by Gregory Phillips,Barbara E. Funnell Pdf

This book opens with an essay on the historical perspective of the study of plasmids, reviewing important events and discoveries that have propelled the field forward. The remaining chapters are divided into six sections, detailing basic biological processes such as replication and inheritance functions, specific plasmid systems, plasmid evolution, and use of plasmids as genetic tools. Chapters include use of genomic approaches for the study of plasmid biology, and a review of plasmids from bacteria, archaea, and eukaryotes is presented. In-depth treatment is given to diversity of plasmid systems in the natural environment, and the development of plasmid use in the laboratory is also covered.

Author : Christopher M. Thomas
Publisher : CRC Press
Page : 459 pages
File Size : 45,5 Mb
Release : 2003-09-02
Category : Science
ISBN : 9780203304334

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Horizontal Gene Pool by Christopher M. Thomas Pdf

Bacteria are the most ubiquitous of all organisms. Responsible for a number of diseases and for many of the chemical cycles on which life depends, they are genetically adaptable. Vital to this adaptability is the existence of autonomous genetic elements-plasmids-which promote genetic exchange and recombination. The genes carried by any particular plasmid may be found in only a few individuals of any species but can also be shared with other species and thus constitute a horizontal gene pool. This book explains the various contributions that plasmids make to this pool: the replication, stable inheritance and transfer modules, the phenotypic markers they carry, the way they evolve, the ways they contribute to their host population and the approaches that we use to study and classify them. It also looks at what we know about their activity in natural communities and the way that they interact with other mobile elements to promote bacterial evolution.

Author : Martin Schleef
Publisher : Wiley-VCH Verlag GmbH
Page : 0 pages
File Size : 51,6 Mb
Release : 2001
Category : DNA vaccines
ISBN : 3527302697

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Plasmids for Therapy and Vaccination by Martin Schleef Pdf

This is the first book specializing in plasmids and their biomedical use, including all relevant aspects of production, applications, quality, and regulations. Readers will discover clinical applications for the wide range of preventive and therapeutic applications using plasmid DNA. The book describes modified vector systems based on plasmids, as well as the potency of genomic research and vector design by informatics. Using the example of fish vaccination, the application of DNA vaccination in veterinary health care is reviewed, followed by a detailed overview of plasmid production technology on an industrial scale. Finally, the book considers regulatory and quality assurance aspects of such new drugs plus thire market potential.

Author : Stuart B. Levy
Publisher : Springer Science & Business Media
Page : 692 pages
File Size : 43,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781468439830

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Molecular Biology, Pathogenicity, and Ecology of Bacterial Plasmids by Stuart B. Levy Pdf

This book resulted from presentations at an international conference on bacterial p1asmids held January 5-9, 1981 in Santo Domingo, Dominican Republic. This was the first meeting of its kind in the Southern Hemisphere. The meeting place was selected for its relaxed and comfortable climate, conducive to interactions among participants. More importantly the locale facilitated the participation of nearby Latin American clinical and research scientists who deal directly with the health manifestations of pathogenic p1asmids. Diseases and socio-economic practices of developing countries exist in the Dominican Republic whose scientific community could directly benefit from having the meeting there. The book includes the talks as well as extended abstracts of poster presentations from the meeting. This combination, which provides readers with reviews as well as recent findings, captures the full scientific exchange which took place during the 5-day meeting. As one indication of pathogenicity related to p1asmids, the conferees were surveyed for gastro-intestina1 problems during and after their stay in the Dominican Republic. The results are summarized at the end of this book.

Author : Edward A. Birge
Publisher : Springer Science & Business Media
Page : 432 pages
File Size : 49,8 Mb
Release : 2013-03-14
Category : Science
ISBN : 9781475719956

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Bacterial and Bacteriophage Genetics by Edward A. Birge Pdf

Bacterial genetics has become one of the cornerstones of basic and applied microbiology and has contributed key knowledge for many of the fundamental advances of modern biology. The second edition of this comprehensive yet concise text, first published in 1981, has been thoroughly updated and redesigned to account for new developments in this rapidly expanding field. All of the major topics in modern bacterial and bacteriophage genetics are presented, among them mutations and mutagenesis, genetics of T4 bacteriophage and other intemperate and temperate phages, transduction, transformation, conjugation and plasmids, recombination and repair, probability laws for prokaryote cultures, as well as applied bacterial genetics.

Author : Donald R. Helinski
Publisher : Springer Science & Business Media
Page : 982 pages
File Size : 42,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461324478

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Plasmids in Bacteria by Donald R. Helinski Pdf

Author : Georg Lipps
Publisher : Caister Academic Press Limited
Page : 0 pages
File Size : 43,8 Mb
Release : 2008
Category : Science
ISBN : 1904455352

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Plasmids by Georg Lipps Pdf

An up to date treatment of the structure, function and application of plasmids with a part-icular emphasis on current and future trends.

Author : Gregory Phillips,Barbara E. Funnell
Publisher : Unknown
Page : 613 pages
File Size : 54,7 Mb
Release : 2004
Category : Plasmids
ISBN : 1683672127

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Plasmid Biology by Gregory Phillips,Barbara E. Funnell Pdf

This book opens with an essay on the historical perspective of the study of plasmids, reviewing important events and discoveries that have propelled the field forward. The remaining chapters are divided into six sections, detailing basic biological processes such as replication and inheritance functions, specific plasmid systems, plasmid evolution, and use of plasmids as genetic tools. Chapters include use of genomic approaches for the study of plasmid biology, and a review of plasmids from bacteria, archaea, and eukaryotes is presented. In-depth treatment is given to diversity of plasmid systems in the natural environment, and the development of plasmid use in the laboratory is also covered.

Author : Edward Schwartz
Publisher : Springer Science & Business Media
Page : 348 pages
File Size : 47,9 Mb
Release : 2009-01-29
Category : Science
ISBN : 9783540854678

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Microbial Megaplasmids by Edward Schwartz Pdf

Megaplasmids are extrachromosomal genetic elements in the size range of 100 kb and larger. They are found in physiologically and phylogenetically diverse groups of bacteria and archaea. By definition, megaplasmids are not essential for the viability of their hosts under all growth conditions, but paradoxically many megaplasmids carry the genetic information for the defining and characteristic traits of the organism in which they reside. Microbial Megaplasmids reviews our knowledge of the extensively studied representatives, such as the catabolic plasmids of the pseudomonads, the rhizobial Sym plasmids, the Ti plasmids of the genus Agrobacterium and the giant enterobacterial virulence plasmids. It also presents snapshots of more recently discovered megaplasmids. The contribution of megaplasmids to the biology of their hosts is described, highlighting the interactions between megaplasmid and chromosomal genes.

Author : Christopher M. Thomas
Publisher : Unknown
Page : 300 pages
File Size : 51,7 Mb
Release : 1989
Category : Science
ISBN : UOM:39015014475811

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Promiscuous Plasmids of Gram-negative Bacteria by Christopher M. Thomas Pdf

Aimed at postgraduate and postdoctoral scientists, this is the first book devoted to the fundamental biology and appplications of broad host range plasmids belonging to groups P, Q, N, and W, which are extensively exploited for in vivo and in vitro genetic manipulation of many Gram-negative bacterial species of industrial and medical importnace.

Author : Kimber G. Hardy
Publisher : IRL Press
Page : 0 pages
File Size : 42,6 Mb
Release : 1993
Category : Microbial genetics
ISBN : 0199634440

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Plasmids by Kimber G. Hardy Pdf

This completely updated and revised second edition of Plasmids: A Practical Approach provides the researcher with detailed protocols for studying bacterial plasmids and for using plasmids and phagemids as vectors. With many new sections and protocols, it is the most up-to-date reference describing the techniques for the study of plasmid replication and maintenance, the fundamental methods for purifying plasmids and introducing them into cells, and the protocols for the mutagenesis and analysis of plasmid-encoded products. The book features further techniques for the study of plasmids and the use of plasmid vectors in such important groups of bacteria as animal and plant pathogens harboring virulence plasmids, Streptomyces, and lactococci. Plus, the book describes the use of plasmid composite vectors for expression of cDNA cloning, and much more. It is a invaluable reference for molecular biologists, microbiologists, and biotechnology researchers. It includes detailed protocols for studying bacterial plasmids and for using both plasmids and phagemids as vectors, techniques for studying fundamental aspects of plasmids, such as replication, are included, as well as methods for using plasmid vectors in important groups of bacteria. Also described are protocols for using phagemids, which are extremely useful tools for genetic engineering.

Author : Karl Esser,Ulrich Kück,Christine Lang-Hinrichs,Paul Lemke,Heinz D. Osiewacz,Ulf Stahl,Paul Tudzynski
Publisher : Springer Science & Business Media
Page : 131 pages
File Size : 40,5 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642825859

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Plasmids of Eukaryotes by Karl Esser,Ulrich Kück,Christine Lang-Hinrichs,Paul Lemke,Heinz D. Osiewacz,Ulf Stahl,Paul Tudzynski Pdf

The possession of plasmids was for a long time recognized only in the bacteria. It is now evident that plasmids, or replicative forms of DNA structurally and experimentally comparable to bacterial plasmids, exist in eukaryotic organisms as well. Such plasmids are in fact common among fungi and higher plants. The present review is undertaken to provide a comprehensive account of the data available on plasmids found in eukaryotic organisms. This review will not consider plasmids of prokaryotic origin, even though certain bacterial plasmids, such as the tumor-inducing (Ti) plasmids of Agrobacterium tumefaciens, may be intimately associated with transformation of the eukaryotic host. This book, moreover, does not consider transformation experiments in eukaryotic hosts involving viral DNA as vectors, although indeed such vectors have been developed for use in plant and animal systems. After a general introduction, providing historical perspective on the nature and role of plasmids, a list of eukaryotic plasmids will be presented according to their origin. This is followed by a detailed discussion of known structure and function. In subsequent chapters the practical implications of eukaryotic plasmids for molecular cloning and biotechnology will be discussed. This latter part traces the development of interest'in biotechnical genetics and gives special consideration to the use of eukaryotic systems for gene cloning. The terminology biotechni cal genetics is introduced to the reader and is used in a general sense as equivalent to genetic engineering. Biotechnical genetics includes, but is not limited to, gene cloning through recombinant DNA technology.