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Author : Donald R. Helinski
Publisher : Springer Science & Business Media
Page : 982 pages
File Size : 41,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461324478
Author : David Summers
Publisher : John Wiley & Sons
Page : 169 pages
File Size : 43,5 Mb
Release : 2009-07-17
Category : Science
ISBN : 9781444313734
Plasmids are closed, circular pieces of DNA that are able to self-replicate and are carried by many bacteria. They provide unique functions for bacteria by allowing them to sexually replicate and to pass on genetic material between each other. Plasmids are also responsible for the genetic factors that give resistance to antibiotics, and provide the enzymes needed to break down poorly metabolised food resources. The author has provided an updated treatment of the structure, function and application of plasmids suitable for undergraduates and medical students. Employing an original teaching perspective--examining plasmids as living organisms with either a symbiotic or parasitic mode of survival--this text provides an important framework for understanding the structure and function of plasmids in an evolutionary context. The most up to date text on plasmids An innovative teaching perspective makes for easy student understanding Contains crucial chapters on the importance of plasmids for clinical and biological research
Author : K. Hardy
Publisher : Springer Science & Business Media
Page : 66 pages
File Size : 43,8 Mb
Release : 1986-06-30
Category : Science
ISBN : 0442317654
This text describes the structure, functions, transmission and applications of bacterial plasmids. The rate of research and accumulating knowledge on bacterial plasmids since the first edition, has established a need for a thorough revision and update. Each chapter has been brought up-to-date, and current developments in the understanding of plasmid replication and transposable elements have received special attention.
Author : Munazza Gull
Publisher : BoD – Books on Demand
Page : 72 pages
File Size : 53,5 Mb
Release : 2019-06-19
Category : Medical
ISBN : 9781838802370
This book captures in a single volume the wealth of information on the plasmid structure, function, and biology of all organisms that have been examined to date. Plasmids exhibit wide variations in size, modes of replication and transmission, host ranges, and the genes they carry and have provided us with a great understanding of basic life principles at the molecular level. Written by experts in the field, this book is a valuable source of up-to-date information, delivering the latest impacts on studies in the areas of plasmid types, genomes, purification analysis, and expression of recombinant proteins in bacteria. Plasmid utilization in the synthesis of plasmid-based vaccines, plasmids as genetic tools, and their applications in ecology and the evolutionary process are also covered. This book is a single source of valuable information for instructors and students in advanced undergraduate and graduate courses on plasmids. It will also appeal to researchers seeking to find new relationships between biological processes that are linked by plasmids to the environment.
Author : Kimber G. Hardy
Publisher : Unknown
Page : 120 pages
File Size : 44,6 Mb
Release : 1981
Category : Bacteria
ISBN : UOM:39015007508008
Author : Karl Esser,Ulrich Kück,Christine Lang-Hinrichs,Paul Lemke,Heinz D. Osiewacz,Ulf Stahl,Paul Tudzynski
Publisher : Springer Science & Business Media
Page : 131 pages
File Size : 54,8 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642825859
The possession of plasmids was for a long time recognized only in the bacteria. It is now evident that plasmids, or replicative forms of DNA structurally and experimentally comparable to bacterial plasmids, exist in eukaryotic organisms as well. Such plasmids are in fact common among fungi and higher plants. The present review is undertaken to provide a comprehensive account of the data available on plasmids found in eukaryotic organisms. This review will not consider plasmids of prokaryotic origin, even though certain bacterial plasmids, such as the tumor-inducing (Ti) plasmids of Agrobacterium tumefaciens, may be intimately associated with transformation of the eukaryotic host. This book, moreover, does not consider transformation experiments in eukaryotic hosts involving viral DNA as vectors, although indeed such vectors have been developed for use in plant and animal systems. After a general introduction, providing historical perspective on the nature and role of plasmids, a list of eukaryotic plasmids will be presented according to their origin. This is followed by a detailed discussion of known structure and function. In subsequent chapters the practical implications of eukaryotic plasmids for molecular cloning and biotechnology will be discussed. This latter part traces the development of interest'in biotechnical genetics and gives special consideration to the use of eukaryotic systems for gene cloning. The terminology biotechni cal genetics is introduced to the reader and is used in a general sense as equivalent to genetic engineering. Biotechnical genetics includes, but is not limited to, gene cloning through recombinant DNA technology.
Author : Christopher M. Thomas
Publisher : CRC Press
Page : 459 pages
File Size : 43,8 Mb
Release : 2003-09-02
Category : Science
ISBN : 9780203304334
Bacteria are the most ubiquitous of all organisms. Responsible for a number of diseases and for many of the chemical cycles on which life depends, they are genetically adaptable. Vital to this adaptability is the existence of autonomous genetic elements-plasmids-which promote genetic exchange and recombination. The genes carried by any particular plasmid may be found in only a few individuals of any species but can also be shared with other species and thus constitute a horizontal gene pool. This book explains the various contributions that plasmids make to this pool: the replication, stable inheritance and transfer modules, the phenotypic markers they carry, the way they evolve, the ways they contribute to their host population and the approaches that we use to study and classify them. It also looks at what we know about their activity in natural communities and the way that they interact with other mobile elements to promote bacterial evolution.
Author : Stuart B. Levy
Publisher : Springer Science & Business Media
Page : 692 pages
File Size : 44,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781468439830
This book resulted from presentations at an international conference on bacterial p1asmids held January 5-9, 1981 in Santo Domingo, Dominican Republic. This was the first meeting of its kind in the Southern Hemisphere. The meeting place was selected for its relaxed and comfortable climate, conducive to interactions among participants. More importantly the locale facilitated the participation of nearby Latin American clinical and research scientists who deal directly with the health manifestations of pathogenic p1asmids. Diseases and socio-economic practices of developing countries exist in the Dominican Republic whose scientific community could directly benefit from having the meeting there. The book includes the talks as well as extended abstracts of poster presentations from the meeting. This combination, which provides readers with reviews as well as recent findings, captures the full scientific exchange which took place during the 5-day meeting. As one indication of pathogenicity related to p1asmids, the conferees were surveyed for gastro-intestina1 problems during and after their stay in the Dominican Republic. The results are summarized at the end of this book.
Author : E. C. C. Lin,Richard N. Goldstein,Michael Syvanen
Publisher : Unknown
Page : 336 pages
File Size : 47,9 Mb
Release : 1984
Category : Genetic regulation
ISBN : UOM:39015033211890
Bcateriology: an overview; Bacterial structure; Bacterial nutrition and metabolism; Growth of bacterial cultures; Gene expression and regulatory mechanisms; DNA replication and mutation bacteria; Genetic exchange between bacteria; Plasmids; General properties of bacterial viruses; Lytic development of phages; Lysogeny in temperature phages; DNA restriction and gene cloning; Chemotherrapy and antibiotics.
Author : D.B. Clewell
Publisher : Springer Science & Business Media
Page : 421 pages
File Size : 45,7 Mb
Release : 2013-06-29
Category : Medical
ISBN : 9781475793574
Bacterial plasmids originating in a wide range of genera are being studied from a variety of perspectives in hundreds of laboratories around the globe. These elements are well known for carrying "special" genes that confer important survival properties, frequently neces sary under atypical conditions. Classic examples of plasmid-borne genes are those provid ing bacterial resistance to toxic substances such as antibiotics, metal ions, and bacte riophage. Often included are those determining bacteriocins, which may give the bacterium an advantage in a highly competitive environment. Genes offering metabolic alternatives to the cell under nutritionally stressed conditions are also commonly found on plasmids, as are determinants important to colonization and pathogenesis. It is likely that in many, if not most, cases plasmids and their passenger determinants represent DNA acquired recently by their bacterial hosts, and it is the characteristic mobility of these elements that enables their efficient establishment in new bacterial cells by the process known as conjugation. Whereas many plasmids are fully capable of promoting their own conjugal transfer, others move only with help from coresident elements. The ability of a plasmid to establish itself in a variety of different species is com mon, and recent studies have shown that transfer can in some cases occur from bacterial cells to eukaryotes such as yeast.
Author : Christopher M. Thomas
Publisher : Unknown
Page : 419 pages
File Size : 46,5 Mb
Release : 2000
Category : Bacterial genetics
ISBN : 0429152906
Bacteria are the most ubiquitous of all organisms being responsible not only for a number of diseases but also for many of the chemical cycles on which life on earth depends. Vital to their genetic adaptability is the existence of autonomous genetic elements-plasmids-which promote genetic exchange and recombination. The genes carried by any particular plasmid may be found only in few individuals of any species but can also be shared with other species and thus constitute a horizontal gene pool. This book deals with the various contributions that plasmids make to this pool-the replication, stab.
Author : Fazal Ahmad
Publisher : Unknown
Page : 624 pages
File Size : 52,8 Mb
Release : 1982
Category : Science
ISBN : UOM:39015006413606
Author : Geoffrey Guy Meynell
Publisher : MIT Press (MA)
Page : 196 pages
File Size : 50,9 Mb
Release : 1973
Category : Bacterial chromosomes
ISBN : WISC:89031254196
This is a sound, scholarly, yet very readable book that organizes the pertinent material on a relatively popular topic in bacterial genetics. In a complicated area where articles are scattered throughout the literature, it should prove an excellent reference source for researchers in microbial genetics and general microbiology, as well as in certain aspects of clinical medicine and in nutrition. Drug-resistance factors are accessory chromosomes, independent of the bacterial chromosome proper, which are of increasing practical concern as they cause a large portion of the antibiotic resistance that is prevalent in medicine and in veterinary practice. Yet these factors are only part of a much larger class of accessory chromosomes known as &"plasmids&" which have played a prominent role in the development of bacterial genetics of molecular biology as a whole. Two other well-known classes are the sex factors, which enable bacteria to transfer their genes to recipients by conjugation, and the bacterial phages&-viruses that grow in bacteria. Despite the great differences in their overt properties, all plasmids exhibit strong fundamental similarities, and it is these general properties rather than their individual peculiarities which are emphasized here. The book first notes how plasmids were discovered. It then discusses the physical structure of their chromosomes, their manner of replication, how they act to bring about conjugation, and other processes they determine. Although the treatment is primarily biological, the book supplies references to laboratory techniques and to the implications of the subject for human and for animal medicine.
Author : František Baluška,Dieter Volkmann,Peter W. Barlow
Publisher : Springer Science & Business Media
Page : 331 pages
File Size : 48,7 Mb
Release : 2006-08-28
Category : Science
ISBN : 9780387360584
This book covers cell-cell channels at all levels of biological organization. The purpose of this book is to document that cells are not physically separated and fully autonomous units of biological life as stated by the currently valid Cell Theory. If not the cell then some lower level unit must fulfill this role. The book deals also with the identity of this elusive unit of biological life.
Author : Edward Schwartz
Publisher : Springer Science & Business Media
Page : 348 pages
File Size : 43,8 Mb
Release : 2009-01-29
Category : Science
ISBN : 9783540854678
Megaplasmids are extrachromosomal genetic elements in the size range of 100 kb and larger. They are found in physiologically and phylogenetically diverse groups of bacteria and archaea. By definition, megaplasmids are not essential for the viability of their hosts under all growth conditions, but paradoxically many megaplasmids carry the genetic information for the defining and characteristic traits of the organism in which they reside. Microbial Megaplasmids reviews our knowledge of the extensively studied representatives, such as the catabolic plasmids of the pseudomonads, the rhizobial Sym plasmids, the Ti plasmids of the genus Agrobacterium and the giant enterobacterial virulence plasmids. It also presents snapshots of more recently discovered megaplasmids. The contribution of megaplasmids to the biology of their hosts is described, highlighting the interactions between megaplasmid and chromosomal genes.