The Black Box Of Biology

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The Black Box of Biology

Michel Morange
The Black Box of Biology Book PDF

Author : Michel Morange
Publisher : Harvard University Press
Page : 529 pages
File Size : 50,8 Mb
Release : 2020-06-09
Category : Science
ISBN : 9780674245259

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The Black Box of Biology by Michel Morange Pdf

In this masterful account, a historian of science surveys the molecular biology revolution, its origin and continuing impact. Since the 1930s, a molecular vision has been transforming biology. Michel Morange provides an incisive and overarching history of this transformation, from the early attempts to explain organisms by the structure of their chemical components, to the birth and consolidation of genetics, to the latest technologies and discoveries enabled by the new science of life. Morange revisits A History of Molecular Biology and offers new insights from the past twenty years into his analysis. The Black Box of Biology shows that what led to the incredible transformation of biology was not a simple accumulation of new results, but the molecularization of a large part of biology. In fact, Morange argues, the greatest biological achievements of the past few decades should still be understood within the molecular paradigm. What has happened is not the displacement of molecular biology by other techniques and avenues of research, but rather the fusion of molecular principles and concepts with those of other disciplines, including genetics, physics, structural chemistry, and computational biology. This has produced decisive changes, including the discoveries of regulatory RNAs, the development of massive scientific programs such as human genome sequencing, and the emergence of synthetic biology, systems biology, and epigenetics. Original, persuasive, and breathtaking in its scope, The Black Box of Biology sets a new standard for the history of the ongoing molecular revolution.

The Black Box of Biology

Michel Morange
The Black Box of Biology Book PDF

Author : Michel Morange
Publisher : Harvard University Press
Page : 529 pages
File Size : 50,5 Mb
Release : 2020-06-09
Category : Science
ISBN : 9780674281363

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The Black Box of Biology by Michel Morange Pdf

In this masterful account, a historian of science surveys the molecular biology revolution, its origin and continuing impact. Since the 1930s, a molecular vision has been transforming biology. Michel Morange provides an incisive and overarching history of this transformation, from the early attempts to explain organisms by the structure of their chemical components, to the birth and consolidation of genetics, to the latest technologies and discoveries enabled by the new science of life. Morange revisits A History of Molecular Biology and offers new insights from the past twenty years into his analysis. The Black Box of Biology shows that what led to the incredible transformation of biology was not a simple accumulation of new results, but the molecularization of a large part of biology. In fact, Morange argues, the greatest biological achievements of the past few decades should still be understood within the molecular paradigm. What has happened is not the displacement of molecular biology by other techniques and avenues of research, but rather the fusion of molecular principles and concepts with those of other disciplines, including genetics, physics, structural chemistry, and computational biology. This has produced decisive changes, including the discoveries of regulatory RNAs, the development of massive scientific programs such as human genome sequencing, and the emergence of synthetic biology, systems biology, and epigenetics. Original, persuasive, and breathtaking in its scope, The Black Box of Biology sets a new standard for the history of the ongoing molecular revolution.

A History of Molecular Biology

Michel Morange
A History of Molecular Biology Book PDF

Author : Michel Morange
Publisher : Harvard University Press
Page : 350 pages
File Size : 40,8 Mb
Release : 2000
Category : History
ISBN : 0674001699

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A History of Molecular Biology by Michel Morange Pdf

Every day it seems the media focus on yet another new development in biology--gene therapy, the human genome project, the creation of new varieties of animals and plants through genetic engineering. These possibilities have all emanated from molecular biology. A History of Molecular Biology is a complete but compact account for a general readership of the history of this revolution. Michel Morange, himself a molecular biologist, takes us from the turn-of-the-century convergence of molecular biology's two progenitors, genetics and biochemistry, to the perfection of gene splicing and cloning techniques in the 1980s. Drawing on the important work of American, English, and French historians of science, Morange describes the major discoveries--the double helix, messenger RNA, oncogenes, DNA polymerase--but also explains how and why these breakthroughs took place. The book is enlivened by mini-biographies of the founders of molecular biology: Delbrück, Watson and Crick, Monod and Jacob, Nirenberg. This ambitious history covers the story of the transformation of biology over the last one hundred years; the transformation of disciplines: biochemistry, genetics, embryology, and evolutionary biology; and, finally, the emergence of the biotechnology industry. An important contribution to the history of science, A History of Molecular Biology will also be valued by general readers for its clear explanations of the theory and practice of molecular biology today. Molecular biologists themselves will find Morange's historical perspective critical to an understanding of what is at stake in current biological research.

Darwin's Black Box

Michael J. Behe
Darwin s Black Box Book PDF

Author : Michael J. Behe
Publisher : Simon and Schuster
Page : 353 pages
File Size : 42,6 Mb
Release : 1996
Category : Evolution (Biology)
ISBN : 0684827549

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Darwin's Black Box by Michael J. Behe Pdf

Behe argues that the complexity of cellular biochemistry argues against Darwin's gradual evolution.

The Panda's Black Box

Nathaniel C. Comfort
The Panda s Black Box Book PDF

Author : Nathaniel C. Comfort
Publisher : JHU Press
Page : 196 pages
File Size : 55,9 Mb
Release : 2007-06-11
Category : Education
ISBN : 080188599X

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The Panda's Black Box by Nathaniel C. Comfort Pdf

Six prominent writers explain the roots of the controversy over Intelligent Design and explore the intellectual, social, and cultural factors that continue to shape it.

Black Boxes

Marco J. Nathan
Black Boxes Book PDF

Author : Marco J. Nathan
Publisher : Oxford University Press
Page : 313 pages
File Size : 48,6 Mb
Release : 2021
Category : Philosophy
ISBN : 9780190095482

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Black Boxes by Marco J. Nathan Pdf

Bricks and boxes -- Between Scylla and Charybdis -- Lessons from the history of science -- Placeholders -- Black-boxing 101 -- History of science 'black-boxing style' -- Diet mechanistic philosophy -- Emergence reframed -- The fuel of scientific progress -- Sailing through the strait.

A History of Biology

Michel Morange
A History of Biology Book PDF

Author : Michel Morange
Publisher : Princeton University Press
Page : 448 pages
File Size : 45,6 Mb
Release : 2023-08-15
Category : Science
ISBN : 9780691253923

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A History of Biology by Michel Morange Pdf

A comprehensive history of the biological sciences from antiquity to the modern era This book presents a global history of the biological sciences from ancient times to today, providing needed perspective on the development of biological thought while shedding light on the field's upheavals and key breakthroughs through the ages. Michel Morange brings to life the dynamic interplay of science, society, and biology’s many subdisciplines, enabling readers to better appreciate the interdisciplinary exchanges that have shaped the field over the centuries. Each chapter of this incisive book focuses on a specific period in the history of biology, describing the major transformations that occurred, the enduring scientific concerns behind these changes, and the implications of yesterday's science for today's. Morange covers everything from the first cell theory to the origins of the concept of ecosystems, and offers perspectives on areas that are often neglected by historians of biology, such as ecology, ethology, and plant biology. Along the way, he highlights the contributions of technology, the important role of hypothesis and experimentation, and the cultural contexts in which some of the most breathtaking discoveries in biology were made. Unrivaled in scope and written by a world-renowned historian of science, A History of Biology is an ideal introduction for students and experts alike, and essential reading for anyone seeking to understand the present state of biological knowledge.

Gene Sharing and Evolution

Joram Piatigorsky
Gene Sharing and Evolution Book PDF

Author : Joram Piatigorsky
Publisher : Harvard University Press
Page : 434 pages
File Size : 54,9 Mb
Release : 2007-02-28
Category : Science
ISBN : 0674023412

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Gene Sharing and Evolution by Joram Piatigorsky Pdf

In Gene Sharing and Evolution Piatigorsky explores the generality and implications of gene sharing throughout evolution and argues that most if not all proteins perform a variety of functions in the same and in different species, and that this is a fundamental necessity for evolution.

Biological Measures of Human Experience across the Lifespan

Lynnette Leidy Sievert,Daniel E. Brown
Biological Measures of Human Experience across the Lifespan Book PDF

Author : Lynnette Leidy Sievert,Daniel E. Brown
Publisher : Springer
Page : 336 pages
File Size : 40,8 Mb
Release : 2016-12-21
Category : Social Science
ISBN : 9783319441030

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Biological Measures of Human Experience across the Lifespan by Lynnette Leidy Sievert,Daniel E. Brown Pdf

This volume explores methods used by social scientists and human biologists to understand fundamental aspects of human experience. It is organized by stages of the human lifespan: beginnings, adulthood, and aging. Explored are particular kinds of experiences - including pain, stress, activity levels, sleep quality, memory, and menopausal hot flashes - that have traditionally relied upon self-reports, but are subject to inter-individual differences in self-awareness or culture-based expectations. The volume also examines other ways in which normally “invisible” phenomena can be made visible, such as the caloric content of foods, blood pressure, fecundity, growth, nutritional status, genotypes, and bone health. All of the chapters in this book address the means by which social scientists and human biologists measure subjective and objective experience.

Computational Methods in Systems Biology

Vincent Danos,Vincent Schachter
Computational Methods in Systems Biology Book PDF

Author : Vincent Danos,Vincent Schachter
Publisher : Springer
Page : 282 pages
File Size : 46,9 Mb
Release : 2005-04-01
Category : Computers
ISBN : 9783540259749

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Computational Methods in Systems Biology by Vincent Danos,Vincent Schachter Pdf

The Computational Methods in Systems Biology (CMSB) workshop series was established in 2003 by Corrado Priami. The purpose of the workshop series is to help catalyze the convergence between computer scientists interested in language design, concurrency theory, software engineering or program verification, and physicists, mathematicians and biologists interested in the systems-level understanding of cellular processes. Systems biology was perceived as being increasingly in search of sophisticated modeling frameworks whether for representing and processing syst- level dynamics or for model analysis, comparison and refinement. One has here a clear-cut case of a must-explore field of application for the formal methods developed in computer science in the last decade. This proceedings consists of papers from the CMSB 2003 workshop. A good third of the 24 papers published here have a distinct formal methods origin; we take this as a confirmation that a synergy is building that will help solidify CMSB as a forum for cross-community exchange, thereby opening new theoretical avenues and making the field less of a potential application and more of a real one. Publication in Springer's new Lecture Notes in Bioinformatics (LNBI) offers particular visibility and impact, which we gratefully acknowledge. Our keynote speakers, Alfonso Valencia and Trey Ideker, gave challenging and somewhat humbling lectures: they made it clear that strong applications to systems biology are still some way ahead. We thank them all the more for accepting the invitation to speak and for the clarity and excitement they brought to the conference.

Explorers of the Black Box

Susan Allport
Explorers of the Black Box Book PDF

Author : Susan Allport
Publisher : Open Road Media
Page : 298 pages
File Size : 53,7 Mb
Release : 2016-06-28
Category : Science
ISBN : 9781504034104

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Explorers of the Black Box by Susan Allport Pdf

Explorers of the Black Box is a scientific adventure story. The “Black Box” is the brain. The “Explorers” are neuroscientists in search of how nerve cells record memories, and they are as ruthless and dauntless as any soldiers of fortune. The book centers around the early, often-controversial research Nobel Prize–winner Eric Kandel. It takes readers behind the scenes of laboratories at Woods Hole, Columbia, Yale, and Princeton to create an absorbing account of how the brain works and of how science itself works.

Environment, Development, and Evolution

Brian Keith Hall,Roy Douglas Pearson,Gerd B. Müller
Environment Development and Evolution Book PDF

Author : Brian Keith Hall,Roy Douglas Pearson,Gerd B. Müller
Publisher : MIT Press
Page : 336 pages
File Size : 45,5 Mb
Release : 2004
Category : Science
ISBN : 0262083191

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Environment, Development, and Evolution by Brian Keith Hall,Roy Douglas Pearson,Gerd B. Müller Pdf

Leading researchers in evolutionary developmental biology seek linkages between, and a synthesis of, development, physiology, endocrinology, ecology, and evolution. Evolutionary developmental biology, also known as evo-devo or EDB, seeks to find links between development and evolution by opening the "black box" of development's role in evolution and in the evolution of developmental mechanisms. In particular, this volume emphasizes the roles of the environment and of hormonal signaling in evo-devo. It brings together a group of leading researchers to analyze the dynamic interaction of environmental factors with developmental and physiological processes and to examine how environmental signals are translated into phenotypic change, from the molecular and cellular level to organisms and groups of organisms. Taken together, these chapters demonstrate the crucial roles of those processes of genetic, developmental, physiological, and hormonal change that underpin evolutionary change in development, morphology, physiology, behavior, and life-history. Part I investigates links between environmental signals and developmental processes that could be preserved over evolutionary time. Several contributors evaluate the work of the late Ryuichi Matsuda, especially his emphasis on the role of the external environment in genetic change and variability ("pan-environmentalism"). Other contributors in part I analyze different aspects of environmental-genetic-evolutionary linkages, including the importance of alternate ontogenies in evolution and the paradox of stability over long periods of evolutionary time. Part II examines the plasticity that characterizes much of development, with contributors discussing such topics as gene regulatory networks and heterochronicity. Part III analyzes the role of hormones and metamorphosis in the evolution of such organisms with alternate life-history stages as lampreys, amphibians, and insects.

Inside the black box

Paul Black,Dylan Wiliam
Inside the black box Book PDF

Author : Paul Black,Dylan Wiliam
Publisher : Granada Learning
Page : 24 pages
File Size : 53,9 Mb
Release : 1998
Category : Education
ISBN : 0708713815

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Inside the black box by Paul Black,Dylan Wiliam Pdf

Offers practical advice on using and improving assessment for learning in the classroom.

Working Inside the Black Box

Paul Black,Christine Harrison,Clare Lee
Working Inside the Black Box Book PDF

Author : Paul Black,Christine Harrison,Clare Lee
Publisher : Granada Learning
Page : 28 pages
File Size : 46,7 Mb
Release : 2004
Category : Education
ISBN : 0708713793

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Working Inside the Black Box by Paul Black,Christine Harrison,Clare Lee Pdf

Offers practical advice on using and improving assessment for learning in the classroom.

Biology Made Real

Christian Moore-Anderson
Biology Made Real Book PDF

Author : Christian Moore-Anderson
Publisher : Christian Moore-Anderson
Page : 193 pages
File Size : 53,7 Mb
Release : 2023-04-05
Category : Education
ISBN : 8210379456XXX

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Biology Made Real by Christian Moore-Anderson Pdf

'This outstanding book... deserves to be very widely read. I hope it makes a major contribution to how school biology is taught.' —Dr Michael J. Reiss, Professor of Science Education, University of London 'This is a book that all teachers, not just biology teachers should read.' —Ben Strathearn-Burrows, Head of Biology, Emanuel School What you'll find inside: —A vision for an integrated and meaningful biology education. —A framework for teaching for meaning-making, which cuts planning time. —Ways of creating a unified narrative across disparate topics. —A taxonomy of understanding that unlocks problem-solving with minimal workload. —Tried and tested examples from mixed-attainment biology classrooms. Introduction I've been motivated to discover what biology is to us as humans. What it means to understand biology, and how I could make it meaningful for my students. I've read as much as I could and reflected, I've discussed and listened, I've taught and observed. While it doesn't cover all aspects of biology education, this book is about sharing what I've learnt on my journey of synthesising and trialling ideas with my secondary-school mixed-attainment biology classes. 'Not only is this book likely to change how you teach biology but also how you perceive yourself within the living world.' —Dr Alex Sinclair, Institute of Education, St Mary's University, Twickenham Chapter 1: Meaningful biology relates principally to organisms: This sets the scene for the whole book. It brings together many threads to define what I see as most meaningful to secondary biology students. And therefore what we could do about it when designing our lessons & curricula and thinking about how students progress through their biology education. Planning for meaning-making has vastly enhanced interest and motivation to learn in my classroom. Chapters 2 & 3: Teaching for meaning using variation theory: Next I introduce a powerful—relatively unknown and often misunderstood—pedagogical theory. Variation theory. In these chapters I set out to show how useful it is—and easy to use—in the secondary biology classroom, with many examples. Chapter 4: How to integrate organisms, ecology & evolution: Now I pull together the previous chapters to present a new framework for teaching for meaning-making that cuts planning time & focuses on biology. 'An excellent text demanding we think not just about what we teach but also why and how.’ —Dr Paul Ganderton, Consultant and researcher Chapter 5: Concepts of the organism that unite a biology course: Here I discuss two concepts that I think can unify all the topics on the curriculum. 1. Seeing biology through thermodynamic systems lens and, 2. Seeing biology through an ecological-evolutionary lens via the concept of life strategies. I lay out the reasons why and discuss how I've introduced these ideas with students. Chapter 6: Teaching systems thinking to help students see interconnectedness: This chapter is dedicated to systems thinking. Firstly I show how stock and flow diagrams are very useful for the biology classroom and give examples. Next, I introduce a new taxonomy of understanding biological systems. Chapter 7: Establishing a thinking classroom: This chapter is focused on the whys and hows of embedding the taxonomy into my biology curricula. I give examples of how I use it and examples of my students answers from lower and upper secondary courses. Chapter 8: Navigating classroom and biological complexity: This chapter rounds up the book by considering the complexity of our subject and the classroom. ‘Biology Made Real comes with an education health warning—be prepared to have your beliefs challenged.' —Dr Alex Sinclair