The Catecholamines In Psychiatric And Neurologic Disorders

Author : C. Raymond Lake,Michael G. Ziegler
Publisher : Butterworth-Heinemann
Page : 366 pages
File Size : 51,6 Mb
Release : 2013-10-22
Category : Health & Fitness
ISBN : 9781483163123

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The Catecholamines in Psychiatric and Neurologic Disorders by C. Raymond Lake,Michael G. Ziegler Pdf

The Catecholamines in Psychiatric and Neurologic Disorders focuses on the contributions of catecholamines (CA) in the modulation of blood pressure, stress and exercise, body movements, memory, learning, emotions, thought processing, appetite, and mediation of psychotropic drug action. The selection first elaborates on the techniques for the assessment and interpretation of catecholamine measurements in neuropsychiatric patients and catecholaminergic response to stress and exercise. Discussions focus on noradrenergic response to isometric exercise, isotonic exercise, effect of acceleration on sympathetic activity, techniques for sympathetic nervous system evaluation, and measurements of CA and their metabolites in cerebrospinal fluid. The text then takes a look at urinary CA in behavioral research on stress; CA in anxiety disorders and mitral valve prolapse; and interaction with neurotransmitters in normal subjects and in patients with selected neurologic diseases. The selection examines noradrenergic responses in postural hypotension, norepinephrine, alcohol, and alcoholism, and catecholamine metabolism in anorexia nervosa. Topics include cerebral catecholamine metabolism in anorexia nervosa; central nervous system norepinephrine and voluntary alcohol drinking; and overview of norepinephrine in selected pediatric disorders. The book is a dependable reference for neuropsychiatrists and readers interested in the contributions of catecholamines on psychiatric disorders.

Author : Robert Vink,Mihai Nechifor
Publisher : University of Adelaide Press
Page : 354 pages
File Size : 51,5 Mb
Release : 2011
Category : Medical
ISBN : 9780987073051

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Magnesium in the Central Nervous System by Robert Vink,Mihai Nechifor Pdf

The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Author : Yogesh Dwivedi
Publisher : CRC Press
Page : 485 pages
File Size : 44,6 Mb
Release : 2012-06-25
Category : Medical
ISBN : 9781439838815

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The Neurobiological Basis of Suicide by Yogesh Dwivedi Pdf

With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.

Author : Timo Siepmann,Kristian Barlinn,Ben Min-Woo Illigens
Publisher : Frontiers Media SA
Page : 96 pages
File Size : 51,6 Mb
Release : 2020-04-02
Category : Electronic
ISBN : 9782889636273

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Integrity of the Autonomic Nervous System in Psychiatric and Neurological Disorders by Timo Siepmann,Kristian Barlinn,Ben Min-Woo Illigens Pdf

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Author : Richard McCarty
Publisher : Oxford University Press, USA
Page : 673 pages
File Size : 42,6 Mb
Release : 2020
Category : Medical
ISBN : 9780190697266

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Stress and Mental Disorders by Richard McCarty Pdf

Stress has been recognized as an important factor in the development or recurrence of various mental disorders, from major depressive disorder to bipolar disorder to anxiety disorders. Stressful stimuli also appear to exert their effects by acting upon individuals with susceptible genotypes. Over the past 50 years, animal models have been developed to study these dynamic interactions between stressful stimuli and genetically susceptible individuals during prenatal and postnatal development and into adulthood. Stress and Mental Disorders: Insights from Animal Models begins with a discussion of the history of psychiatric diagnosis and the recent goal of moving toward precision psychiatry, followed by a review of clinical research on connections between stressful stimuli and the development of psychiatric disorders. Chapters are also included on neuroendocrine, immune, and brain systems involved in responses to stress. Additional chapters focus on the development of animal models in psychiatry and the susceptibility of the developing organism to stressful stimuli. Subsequent chapters are devoted to animal models of specific stress-sensitive psychiatric disorders, including schizophrenia, autism spectrum disorders, bipolar disorder, anxiety disorders, depression, and post-traumatic stress disorder. These chapters also focus on identification of promising molecular targets for development of new drug therapies. The section concludes with a chapter on animal models of resilience to stress-induced behavioral alterations as a newer approach to understanding why some animals are susceptible to stress and others are resilient, even though they are essentially genetically identical. The final chapter discusses how these basic laboratory studies are providing promising leads for future breakthroughs in the diagnosis, treatment, and prevention of mental disorders.

Author : James McGaugh
Publisher : Springer Science & Business Media
Page : 288 pages
File Size : 51,9 Mb
Release : 2013-03-13
Category : Science
ISBN : 9781468430608

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The Chemistry of Mood, Motivation, and Memory by James McGaugh Pdf

This volume is based on presentations at an interdisciplinary conference on The Chemistry of Mood, Motivation and Memory which was held at the University of California, San Francisco in October, 1971. The conference was sponsored and supported by the Division of Continuing Education in Health Sciences. We thank Dr. Ruben Dixon and his staff for help in planning the conference and for attending to all of the organizational details. We particularly thank the participants for their contributions to the conference and for their cooperation in preparing the manu scripts based on their conference presentations. All of the details involved in preparing the volume for publi cation were handled by Karen Dodd. We are grateful to her for her tireless, efficient and productive efforts. We hope that this volume will help to stimulate further interest as well as understanding of the biochemical bases of our behavior. James L. McGaugh v CONTRIBUTORS Bernard W. Agranoff, Ph.D. Department of Psychiatry Mental Health Research Institute The University of Michigan Ann Arbor, Michigan Samuel H. Barondes, M.D. Professor of Psychiatry School of Medicine University of California at San Diego La Jolla, California Barry D. Berger, Ph.D. Wyeth Laboratories Philadelphia, Pennsylvania Enoch Callaway, M.D. Professor of Psychiatry University of California School of Medicine San Francisco, California J. Anthony Deutsch, Ph.D. Professor of Psychology University of California at San Diego La Jolla, California Edward Glassman, Ph.D.

Author : Michael R. Trimble
Publisher : John Wiley & Sons
Page : 488 pages
File Size : 48,8 Mb
Release : 1996
Category : Medical
ISBN : 0471953741

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Biological Psychiatry by Michael R. Trimble Pdf

Biological psychiatry, a body of knowledge which has revolutionised our understanding of most of the major psychiatric disorders, has progressed significantly since the first edition of this book. Written by a leading expert in his field, this new volume reflects the major advances which have occurred and provides a fully updated and authoritative text on the subject, with many more references and illustrations. Presented in a new, easy-to-read, modern format, this indispensable reference work will appeal to a wide, international audience in the fields of psychiatry, psychology and mental health care. Reviews of the First Edition: "A handy, readable book which psychiatrists in training would be better for reading; it would also appeal to psychiatrists in need of a good refresher course." Journal of Neurology, Neurosurgery and Psychiatry "The author has undertaken the task of traversing the jungle of current information in biological psychiatry and, as an overview of much of the recent biological research, has provided an excellent sampling of work in biochemical and neuropsychiatric research." Contemporary Psychology "This is a masterpiece of compression; a valuable and up-to-date text." British Journal of Psychiatry

Author : Anonim
Publisher : Academic Press
Page : 1129 pages
File Size : 41,9 Mb
Release : 1997-10-20
Category : Medical
ISBN : 9780080581347

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Catecholamines: Bridging Basic Science with Clinical Medicine by Anonim Pdf

This volume in Advances in Pharmacology focuses on all aspects of catecholamine research, from very basic to medical. It is broad based and covers many areas within physiology and medicine.

Author : Neil Schneiderman,Stephen M. Weiss,Peter G. Kaufmann
Publisher : Springer Science & Business Media
Page : 713 pages
File Size : 51,6 Mb
Release : 2013-11-21
Category : Medical
ISBN : 9781489909060

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Handbook of Research Methods in Cardiovascular Behavioral Medicine by Neil Schneiderman,Stephen M. Weiss,Peter G. Kaufmann Pdf

Cardiovascular disease continues to be the number ioral medicine" was developed and shaped into the one source of morbidity and mortality in our coun following definition: try. Despite a 35% reduction since 1964, these Behavioral medicine is the interdisciplinary field con diseases, particularly coronary heart disease cerned with the development and integration of behav (CHD), claim nearly 1,000,000 lives each year in ioral and biomedical science knowledge and techniques the United States (Havlik & Feinleib, 1979). relevant to the understanding of health and illness and The Framingham study, among others, has iden the application of this knowledge and these techniques to prevention, diagnosis, treatment and rehabilitation. tified three major risk factors implicated in the de (Schwartz & Weiss, 1978) velopment of CHD: smoking, elevated serum cho lesterol, and high blood pressure (Castelli et at., This concept of "biobehavioral" collaboration 1986). Given that these factors account for less challenged scientists and clinicians of many disci than 50% of the variance associated with CHD plines to consider how they might more effectively (Jenkins, 1976), it has become obvious that addi develop diagnostic, treatment, and prevention tional risk factors must be identified if further pro strategies by merging their perspectives to address gress is to be made in disease prevention and simultaneously, among others, behavioral, psy control.

Author : National Institutes of Health (U.S.)
Publisher : Unknown
Page : 690 pages
File Size : 43,9 Mb
Release : 1986
Category : Medical research personnel
ISBN : UOM:39015035701302

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Scientific Directory and Annual Bibliography by National Institutes of Health (U.S.) Pdf

Author : Leo Montada,Sigrun-Heide Filipp,Melvin J. Lerner
Publisher : Routledge
Page : 582 pages
File Size : 41,7 Mb
Release : 2014-01-14
Category : Psychology
ISBN : 9781317782759

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Life Crises and Experiences of Loss in Adulthood by Leo Montada,Sigrun-Heide Filipp,Melvin J. Lerner Pdf

A result of a conference at the University of Trier, Germany, this volume mirrors its goals: * to provide an overview of recent advances in research on critical life events and the losses associated with them * to collect and stimulate new perspectives for the analysis of these events * to compare the psychology of victims experiencing stress and losses with the psychology of observers in their reactions to victims. Designed to prevent developmental psychological myths in the area of life crises, this collection questions, on an empirical basis, the adequacy of several widespread generalizations. At the same time its contributors attempt to draw paths to conceptualizations and theories in general psychology and social psychology which promise to be helpful in analyzing and interpreting phenomena in the field of life crises.

Author : Tahira Farooqui,Akhlaq A. Farooqui
Publisher : Academic Press
Page : 432 pages
File Size : 45,7 Mb
Release : 2016-07-12
Category : Medical
ISBN : 9780128036167

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Trace Amines and Neurological Disorders by Tahira Farooqui,Akhlaq A. Farooqui Pdf

Trace Amines and Neurological Disorders: Potential Mechanisms and Risk Factors explores trace amines which, under normal conditions, are present in the mammalian brain and peripheral nervous tissues at very low (nanomolar) concentrations. However, in a diverse array of human pathologies ranging from substance abuse, depression, attention deficit hyperactivity disorder, eating disorders, schizophrenia, and other neurological and neuropsychiatric diseases, the levels of trace amines are unusually high with an imbalance in their functions. Furthermore, the rapid turnover of trace amines is evidenced by their dramatic increases following treatment with monoamine oxidase inhibitors (MAOI) or deletion of the MAO genes. This suggests that the concentration of trace amines may be considerably higher at neuronal synapses than predicted by steady-state measures, implicating some pathophysiological role. Therefore, understanding molecular mechanisms and developing selective agonists and antagonists for trace amine-associated receptors (TAARs) has become a good approach for treating these diseases. Although the effects of trace amines at low physiological concentrations in mammalian species have been difficult to demonstrate, they may serve to maintain the neuronal activity of other monoamine neurotransmitters by possessing postsynaptic modulatory effects, particularly dopamine and serotonin, within defined physiological limits. Such an effect of trace amines makes them ideal candidates for the development of novel therapeutics for a wide range of human disorders. This book presents up-to-date, cutting-edge, and comprehensive information on the link between trace amines and neurological disorders. Focuses on recent findings on trace amines, providing insights into the functional significance, molecular mechanisms, and biological relevance of TAARS in neurological disorders Edited work with chapters authored by leaders in the field from around the globe, the broadest, most expert coverage available Provides cutting-edge research on trace amines-mediated signaling in vertebrate model systems

Author : National Library of Medicine (U.S.)
Publisher : Unknown
Page : 1736 pages
File Size : 55,9 Mb
Release : 2024-07-01
Category : Medicine
ISBN : STANFORD:36105009872693

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Current Catalog by National Library of Medicine (U.S.) Pdf

Author : National Library of Medicine (U.S.)
Publisher : Unknown
Page : 1728 pages
File Size : 47,6 Mb
Release : 1985
Category : Medicine
ISBN : MINN:31951M013754299

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National Library of Medicine Current Catalog by National Library of Medicine (U.S.) Pdf

Author : David B. Arciniegas,C. Alan Anderson,Christopher M. Filley
Publisher : Cambridge University Press
Page : 685 pages
File Size : 42,9 Mb
Release : 2013-01-24
Category : Medical
ISBN : 9780521875011

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Behavioral Neurology & Neuropsychiatry by David B. Arciniegas,C. Alan Anderson,Christopher M. Filley Pdf

The merger of behavioral neurology and neuropsychiatry into a single medical subspecialty, Behavioral Neurology & Neuropsychiatry, requires an understanding of brain-behavior relationships and a clinical approach that transcends the traditional perspectives of neurology and psychiatry. Designed as a primer of concepts and principles, and authored by a multidisciplinary group of internationally known clinical neuroscientists, this book divides into three sections: • Structural and Functional Neuroanatomy (Section I) addresses the neuroanatomy and phenomenology of cognition, emotion, and behavior • Clinical Assessment (Section II) describes neuropsychiatric history taking, neurological and mental status examinations, neuropsychological assessment, and neuroimaging, electrophysiologic, and laboratory methods • Treatment (Section III) discusses environmental, behavioral, rehabilitative, psychological, social, pharmacological, and procedural interventions for cognitive, emotional, and behavioral disorders. By emphasizing the principles of Behavioral Neurology & Neuropsychiatry, this book will improve your understanding of brain-behavior relationships and inform your care of patients and families affected by neurobehavioral disorders.