The Complement Factsbook

Author : Scott R. Barnum,Theresa N. Schein
Publisher : Academic Press
Page : 512 pages
File Size : 47,9 Mb
Release : 2017-10-19
Category : Science
ISBN : 9780128104217

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The Complement FactsBook by Scott R. Barnum,Theresa N. Schein Pdf

The Complement FactsBook, Second Edition, provides in-depth insights and an overview of the components of the complement system. This new edition highlights the use of newly recommended complement nomenclature, covering new pathways and proteins and adding information on mouse homologs. It is a completely revised and updated edition containing entries on all components of the complement system, and is an excellent source of one-stop shopping for complement information and references. It is the most convenient compilation of biochemical, biological and molecular biology for complementologists and those new in the field. This new edition is expanded to include relevant updates and topics that have evolved since the last edition was published, including C1q and Lectins, C3 Family, Serine Proteases, Serum Regulators of Complement Activation, Cell Surface Proteins, and Terminal Pathway Proteins. Domain Structure diagrams are incorporated to clearly illustrate the relationships between all the complement proteins, both within families and between families. Introduces complement function, simply described for each function Includes the cDNA sequences that are marked with intron/exon boundaries, facilitating genetic studies Presents detailed structural information, including cDNA and gene structure for all proteins Incorporates domain structures diagrams, which beautifully illustrate the relationship between all the complement proteins, both within, and between, families

Author : Scott R. Barnum
Publisher : Academic Press
Page : 237 pages
File Size : 42,5 Mb
Release : 1999-10-28
Category : Medical
ISBN : 9780080529554

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The Complement FactsBook by Scott R. Barnum Pdf

The Complement FactsBook contains entries on all components of the Complement System, including C1q and Lectins, C3 Family, Serine Proteases, Serum Regulators of Complement Activation, Cell Surface Proteins, and Terminal Pathway Proteins. Domain Structure diagrams are incorporated to clearly illustrate the relationships between all the complement proteins, both within families and between families. The FactsBook also includes the cDNA sequences, marked with intron/exon boundaries, which will facilitate genetic studies. Includes the cDNA sequences, marked with intron/exon boundaries, facilitating genetic studies Presents detailed structural information including cDNA and gene structure for all proteins Introduces complement function, simply described for each function Data is as up-to-date as possible, including unpublished work from many contributors Incorporates domain structures diagrams, which beautifully illustrate the relationship between all the complement proteins, both within, and between, familiesEach chapter has been written by an expert in the field Data is as up-to-date as possible, including unpublished work from many contributors Entries provide information on: Alternative nomenclature, Physiochemical properties, Structure and function, Tissue distribution and regulation expression, Protein sequence/modules, Chromosomal location, Genomic structure, Database accession numbers, Deficiency and polymorphic variants, Key references

Author : Marie-Paule Lefranc,Gerard Lefranc
Publisher : Gulf Professional Publishing
Page : 472 pages
File Size : 55,6 Mb
Release : 2001-05-29
Category : Medical
ISBN : 9780124413511

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The Immunoglobulin FactsBook by Marie-Paule Lefranc,Gerard Lefranc Pdf

The FactsBook series has established itself as the best source of easily accessible and accurate facts about protein groups. Books in the series use an easy-to-follow format and are meticulously researched and compiled by experts in the field. The Immunoglobulin FactsBook is the first published reference for all 203 human functional and ORF immunoglobulin genes. It is complete and standardized and employs nomenclature approved by the HUGO Nomenclature Committee.

Author : Steven G.E. Marsh,Peter Parham,Linda D. Barber
Publisher : Elsevier
Page : 416 pages
File Size : 45,7 Mb
Release : 1999-12-13
Category : Medical
ISBN : 0080542506

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The HLA FactsBook by Steven G.E. Marsh,Peter Parham,Linda D. Barber Pdf

The HLA FactsBook presents up-to-date and comprehensive information on the HLA genes in a manner that is accessible to both beginner and expert alike. The focus of the book is on the polymorphic HLA genes (HLA-A, B, C, DP, DQ, and DR) that are typed for in clinical HLA laboratories. Each gene has a dedicated section in which individual entries describe the structure, functions, and population distribution of groups of related allotypes. Fourteen introductory chapters provide a beginner's guide to the basic structure, function, and genetics of the HLA genes, as well as to the nomenclature and methods used for HLA typing. This book will be an invaluable reference for researchers studying the human immune response, for clinicians and laboratory personnel involved in clinical and forensic HLA typing, and for human geneticists, population biologists, and evolutionary biologists interested in HLA genes as markers of human diversity. Introductory chapters provide good general overview of HLA field for novice immunologists and geneticists Up-to-date, complete listing of HLA alleles Invaluable reference resource for immunologists, geneticists, and cell biologists Combines both structural and functional information, which has never been compiled in a single reference book previously Serological specificity of allotypes Identity of material sequenced including ethnic origin Database accession numbers Population distribution Peptide binding specificities T cell epitopes Amino acid sequences of allotypes Key references

Author : Vincent Laudet,Hinrich Gronemeyer
Publisher : Gulf Professional Publishing
Page : 486 pages
File Size : 54,9 Mb
Release : 2002
Category : Medical
ISBN : 0124377351

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The Nuclear Receptor FactsBook by Vincent Laudet,Hinrich Gronemeyer Pdf

The FactsBook Series has established itself as the best source of easily accessible and accurate facts about protein groups. They use an easy-to-follow format and are researched and compiled by experts in the field. This Factsbook is devoted to nuclear receptors. The first section presents an introduction and describes the mode of action of the receptors in general. The second section of the book contains detailed entries covering each type of receptor. Entries provide information on: Nomenclature and structure, Isolation, DNA binding properties, Ligands, Expression, Target genes, Knockouts, Disease association, Gene structure, promoter and isoforms, Chromosomal location, Amino acid sequences, Key references

Author : Katherine A. Fitzgerald,Luke A.J. O'Neill,Robin E. Callard,Andy J.H. Gearing
Publisher : Academic Press
Page : 534 pages
File Size : 49,6 Mb
Release : 2001-10-09
Category : Medical
ISBN : 0121551423

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The Cytokine Factsbook and Webfacts by Katherine A. Fitzgerald,Luke A.J. O'Neill,Robin E. Callard,Andy J.H. Gearing Pdf

Completely revised and expanded, this second edition of The Cytokine FactsBook is the most up-to-date reference manual available for all current well-characterized interleukins, cytokines, and their receptors. An additional 52 cytokines are included, doubling the number of entries from the previous edition. The key properties of each cytokine are described and presented in a very accessible format with diagrams for each of the receptors. The Cytokine FactsBook includes free online access to the regularly updated Cytokine Webfacts. Cytokine Webfacts is a web-based comprehensive compendium of facts about cytokines and their receptors that includes a variety of data representations, such as text, signal pathway diagrams and 3D images. This exciting resource is integrated into other databases via hypertext links to provide a unique network, and contains a web-enabled version of RasMol for viewing structures.

Author : Anonim
Publisher : Elsevier
Page : 336 pages
File Size : 42,7 Mb
Release : 2000-08-24
Category : Science
ISBN : 0080525970

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The Adhesion Molecule FactsBook by Anonim Pdf

This updated and expanded Second Edition of The Adhesion Molecule FactsBook has nearly double the number of entries of the First Edition, and provides a compendium of the major cell surface adhesion molecules. The introductory chapters detail the organization of the data in the entries section, provide a background to the main adhesion molecule families, and inform the reader how to access information on adhesion molecules on the Internet. The entries have been designed to allow the reader to quickly establish the main structure and functional features of each molecule and where to find information. alternative nomenclature tissue distribution and regulation of expression ligands gene organization and chromosomal location protein structure and molecular weights amino acid sequence of the most commonly studied organisms PIR, SWISSPROT, and EMBL/GenBank accession numbers biological function key references

Author : Marie-Paule Lefranc,Gerard Lefranc
Publisher : Elsevier
Page : 397 pages
File Size : 51,8 Mb
Release : 2001-07-13
Category : Medical
ISBN : 9780080542645

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The T Cell Receptor FactsBook by Marie-Paule Lefranc,Gerard Lefranc Pdf

The T Cell Receptor FactsBook contains entries on all the 176 functional variable, diversity, joining, and constant regions of the human T cell receptor, including alpha, beta, gamma, and delta loci. Introductory chapters summarize information of T cell receptor chain synthesis, chromosomal location, and an overview of the human T cell receptor loci.

Author : Hans G. Drexler
Publisher : Academic Press
Page : 733 pages
File Size : 49,9 Mb
Release : 2000-09-04
Category : Medical
ISBN : 9780080535449

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The Leukemia-Lymphoma Cell Line Factsbook by Hans G. Drexler Pdf

This book represents an essential reference manual for all of the well-characterized leukemia-lymphoma cell lines currently available. It provides the most important facts, using the succinct and user-friendly format that has made the FactsBooks so popular with scientists and clinical researchers. Introductory chapters provide background and perspective for culturing malignant hematopoietic (blood forming) cell lines. These chapters are followed by over 400 comprehensive individual entries. Each cell line entry highlights essential clinical, immunological, genetic, and functional features and includes a comprehensive listing of references. Key Features * the full spectrum of malignant cell lines from all hematopoietic cell lineages * sister cell lines and relevant subclones * clinical data: patient, diagnosis, treatment status, and specimen source * authentication of derivation and availability * immunophenotype * cytogenetic karyotype * translocations and fusion genes * receptor gene rearrangements and genetic alterations * cell cultures aspects: establishment, medium, doubling time, growth * cytochemical profile * cytokine production and response to cytokines * proto-oncogene and transcription factor expression/alteration * functional features: differentiation induction, heterotransplantability * special unique features * key references

Author : José A. Stoute
Publisher : Springer
Page : 149 pages
File Size : 43,9 Mb
Release : 2018-07-03
Category : Medical
ISBN : 9783319772585

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Complement Activation in Malaria Immunity and Pathogenesis by José A. Stoute Pdf

Plasmodium falciparum malaria is responsible for the deaths of nearly 500,000 people each year. Much attention has been paid to antibody and cellular mechanisms of immunity against this pathogen. By contrast, the role that the complement system plays in immunity and pathogenesis in this infection is not very well recognized or understood. Based on the work of a number of research groups, we know that complement plays an important role in these processes. In this book, some of the leading scientists in the field discuss the mechanisms of complement activation during malaria infection as well as the role of complement in the pathogenesis of key syndromes such as severe malarial anemia, cerebral malaria, and placental malaria. In addition, they review recently-identified complement evasion strategies of P. falciparum merozoites, and how these mechanisms may translate into paradoxical enhancement of infection rather than protection. Finally, they also discuss the role of the mosquito complement system on immunity against the parasite.

Author : Janos Szebeni
Publisher : Springer Science & Business Media
Page : 565 pages
File Size : 51,7 Mb
Release : 2007-05-08
Category : Medical
ISBN : 9781402080562

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The Complement System by Janos Szebeni Pdf

As a phylogenetically old system complement is now regarded as a part of innate immunity. But it is much more than that. It bridges innate and adapted immunity, participates not only in host defense but also in many essential physiological processes, old and new diseases and adverse conditions. Indeed, complement became a term that almost defies categorization. What was for a long time a subject for a limited number of specialists has now moved into the mainstream of experimental and clinical immunology. In 1973 I visited the Basel Institute of Immunology and met its director, the eminent scientist and Nobel laureate Nils Jerne. When I entered his office he greeted me with the following words: “Complement, does that really exist?” I was never certain whether he wanted only to tease me or whether he sincerely believed that the complement system was an unimportant biological curiosity, a misstep of evolution. But, of course, missteps do not survive the evolutionary process. Little did I foresee the dramatic developments of recent years when Hans J. Müller-Eberhard and I started to unravel the specifics of the action of the cobra venom factor on the complement system in 1968 and defined a new pathway to its activation. An elucidation of the role of the system in diseases and its control for therapeutic reasons is now getting closer to actual realization in the clinic although many problems, in particular those of highly specificinhibition free of side effects, have still to be resolved.

Author : Menno C. van Zelm,Loems Ziegler-Heitbrock,Andrew M. Collins,Pablo Engel,Sanny K. Chan
Publisher : Frontiers Media SA
Page : 131 pages
File Size : 50,8 Mb
Release : 2021-02-03
Category : Medical
ISBN : 9782889664450

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Nomenclature: Avoiding Babylonian Speech Confusion in Present Day Immunology by Menno C. van Zelm,Loems Ziegler-Heitbrock,Andrew M. Collins,Pablo Engel,Sanny K. Chan Pdf

We acknowledge the initiation and support of this Research Topic by the International Union of Immunological Societies (IUIS). A/Prof. Menno van Zelm currently serves as the chairman for the IUIS Nomenclature Committee; Prof. Pablo Engel is the chair of the IUIS CD Nomenclature Sub-Committee; Prof. Loems Ziegler-Heitbrock is the chair of the IUIS Monocytes and Dendritic Cells in Blood Sub-Committee; Asst. Prof. Sanny Chan is a member of the WHO / IUIS Allergen Nomenclature Sub-Committee and A/Prof. Andrew Collins is co-chair of the Germline Gene Database (GLDB) Working Group of the Adaptive Immune Receptor Repertoire community (AIRR-C) and chair of the Inferred Allele Review Committee (IARC).

Author : Barbara Rolfe,Ruben Pio,Trent M. Woodruff,Maciej M. Markiewski,Helga D. Manthey
Publisher : Frontiers Media SA
Page : 107 pages
File Size : 50,8 Mb
Release : 2020-03-23
Category : Electronic
ISBN : 9782889635764

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The Role of Complement in Tumors by Barbara Rolfe,Ruben Pio,Trent M. Woodruff,Maciej M. Markiewski,Helga D. Manthey Pdf

Author : Selim Sözen,Seyfi Emir
Publisher : BoD – Books on Demand
Page : 308 pages
File Size : 52,9 Mb
Release : 2023-05-03
Category : Electronic
ISBN : 9781803559308

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Breast Cancer Updates by Selim Sözen,Seyfi Emir Pdf

Author : Martin Flajnik
Publisher : Lippincott Williams & Wilkins
Page : 3597 pages
File Size : 47,9 Mb
Release : 2022-07-19
Category : Medical
ISBN : 9781975142520

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Paul's Fundamental Immunology by Martin Flajnik Pdf

Selected as a Doody's Core Title for 2022! Defining the field of immunology for 40 years, Paul’s Fundamental Immunology continues to provide detailed, authoritative, up-to-date information that uniquely bridges the gap between basic immunology and the disease process. The fully revised 8th edition maintains the excellence established by Dr. William E. Paul, who passed away in 2015, and is now under new editorial leadership of Drs. Martin F. Flajnik, Nevil J. Singh, and Steven M. Holland. It’s an ideal reference and gold standard text for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role.