The Cutter Incident

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The Cutter Incident

Paul A. Offit
The Cutter Incident Book PDF

Author : Paul A. Offit
Publisher : Yale University Press
Page : 260 pages
File Size : 46,8 Mb
Release : 2007-09-18
Category : History
ISBN : 0300126050

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The Cutter Incident by Paul A. Offit Pdf

Vaccines have saved more lives than any other single medical advance. Yet today only four companies make vaccines, and there is a growing crisis in vaccine availability. Why has this happened? This remarkable book recounts for the first time a devastating episode in 1955 at Cutter Laboratories in Berkeley, California, thathas led many pharmaceutical companies to abandon vaccine manufacture. Drawing on interviews with public health officials, pharmaceutical company executives, attorneys, Cutter employees, and victims of the vaccine, as well as on previously unavailable archives, Dr. Paul Offit offers a full account of the Cutter disaster. He describes the nation's relief when the polio vaccine was developed by Jonas Salk in 1955, the production of the vaccine at industrial facilities such as the one operated by Cutter, and the tragedy that occurred when 200,000 people were inadvertently injected with live virulent polio virus: 70,000 became ill, 200 were permanently paralyzed, and 10 died. Dr. Offit also explores how, as a consequence of the tragedy, one jury's verdict set in motion events that eventually suppressed the production of vaccines already licensed and deterred the development of new vaccines that hold the promise of preventing other fatal diseases.

Vaccine: The Controversial Story of Medicine's Greatest Lifesaver

Arthur Allen
Vaccine The Controversial Story of Medicine s Greatest Lifesaver Book PDF

Author : Arthur Allen
Publisher : W. W. Norton & Company
Page : 542 pages
File Size : 40,9 Mb
Release : 2008-05-17
Category : Medical
ISBN : 9781324036357

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Vaccine: The Controversial Story of Medicine's Greatest Lifesaver by Arthur Allen Pdf

"A timely, fair-minded and crisply written account."—New York Times Book Review Vaccine juxtaposes the stories of brilliant scientists with the industry's struggle to produce safe, effective, and profitable vaccines. It focuses on the role of military and medical authority in the introduction of vaccines and looks at why some parents have resisted this authority. Political and social intrigue have often accompanied vaccination—from the divisive introduction of smallpox inoculation in colonial Boston to the 9,000 lawsuits recently filed by parents convinced that vaccines caused their children's autism. With narrative grace and investigative journalism, Arthur Allen reveals a history illuminated by hope and shrouded by controversy, and he sheds new light on changing notions of health, risk, and the common good.

Vaccination in America

Richard J. Altenbaugh
Vaccination in America Book PDF

Author : Richard J. Altenbaugh
Publisher : Springer
Page : 355 pages
File Size : 51,5 Mb
Release : 2018-08-02
Category : History
ISBN : 9783319963495

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Vaccination in America by Richard J. Altenbaugh Pdf

The success of the polio vaccine was a remarkable breakthrough for medical science, effectively eradicating a dreaded childhood disease. It was also the largest medical experiment to use American schoolchildren. Richard J. Altenbaugh examines an uneasy conundrum in the history of vaccination: even as vaccines greatly mitigate the harm that infectious disease causes children, the process of developing these vaccines put children at great risk as research subjects. In the first half of the twentieth century, in the face of widespread resistance to vaccines, public health officials gradually medicalized American culture through mass media, public health campaigns, and the public education system. Schools supplied tens of thousands of young human subjects to researchers, school buildings became the main dispensaries of the polio antigen, and the mass immunization campaign that followed changed American public health policy in profound ways. Tapping links between bioethics, education, public health, and medical research, this book raises fundamental questions about child welfare and the tension between private and public responsibility that still fuel anxieties around vaccination today.

How to Make a Vaccine

John Rhodes
How to Make a Vaccine Book PDF

Author : John Rhodes
Publisher : University of Chicago Press
Page : 185 pages
File Size : 44,9 Mb
Release : 2021-04-12
Category : Medical
ISBN : 9780226792651

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How to Make a Vaccine by John Rhodes Pdf

Distinguished expert in vaccine development John Rhodes tells the story of the first approved COVID-19 vaccines and offers an essential, up-to-the-minute primer on how scientists discover, test, and distribute vaccines. As the COVID-19 pandemic has affected every corner of the world, changing our relationship to our communities, to our jobs, and to each other, the most pressing question has been—when will it end? Researchers around the globe are urgently trying to answer this question by racing to test and distribute a vaccine that could end the greatest public health threat of our time. In How to Make a Vaccine, an expert who has firsthand experience developing vaccines tells an optimistic story of how three hundred years of vaccine discovery and a century and a half of immunology research have come together at this powerful moment—and will lead to multiple COVID-19 vaccines. Dr. John Rhodes draws on his experience as an immunologist, including working alongside a young Anthony Fauci, to unravel the mystery of how vaccines are designed, tested, and produced at scale for global deployment. Concise and accessible, this book describes in everyday language how the immune system evolved to combat infection, how viruses responded by evolving ways to evade our defenses, and how vaccines do their work. That history, and the pace of current research developments, make Rhodes hopeful that multiple vaccines will protect us. Today the complex workings of the immune system are well understood. The tools needed by biomedical scientists stand ready to be used, and more than 160 vaccine candidates have already been produced. But defeating COVID-19 won’t be the end of the story: Rhodes describes how discoveries today are also empowering scientists to combat future threats to global health, including a recent breakthrough in the development of genetic vaccines, which have never before been used in humans. As the world prepares for a vaccine, Rhodes offers a current and informative look at the science and strategies that deliver solutions to the crisis.

Polio Across the Iron Curtain

Dóra Vargha
Polio Across the Iron Curtain Book PDF

Author : Dóra Vargha
Publisher : Cambridge University Press
Page : 267 pages
File Size : 49,5 Mb
Release : 2018-11
Category : History
ISBN : 9781108420846

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Polio Across the Iron Curtain by Dóra Vargha Pdf

Through the lens of polio, Dóra Vargha looks anew at international health, communism and Cold War politics. This title is also available as Open Access.

Vaccinated

Paul A. Offit, M.D.
Vaccinated Book PDF

Author : Paul A. Offit, M.D.
Publisher : HarperCollins
Page : 323 pages
File Size : 41,6 Mb
Release : 2022-02-01
Category : Medical
ISBN : 9780063251762

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Vaccinated by Paul A. Offit, M.D. Pdf

Vaccines save millions of lives every year, and one man, Maurice Hilleman, was responsible for nine of the big fourteen. Paul Offit recounts his story and the story of vaccines Maurice Hilleman discovered nine vaccines that practically every child gets, rendering formerly dread diseases—including often devastating ones such as mumps and rubella—practically forgotten. Paul A. Offit, a vaccine researcher himself, befriended Hilleman and, during the great man’s last months, interviewed him extensively about his life and career. Offit makes an eloquent and compelling case for Hilleman’s importance, arguing that, like Jonas Salk, his name should be known to everyone. But Vaccinated is also enriched and enlivened by a look at vaccines in the context of modern medical science and history, ranging across the globe and throughout time to take in a fascinating cast of hundreds, providing a vital contribution to the continuing debate over the value of vaccines.

Polio

Thomas Abraham
Polio Book PDF

Author : Thomas Abraham
Publisher : Oxford University Press
Page : 128 pages
File Size : 44,9 Mb
Release : 2018-06-29
Category : Medical
ISBN : 9781787380875

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Polio by Thomas Abraham Pdf

In 1988, the World Health Organization launched a twelve-year campaign to wipe out polio. Thirty years and several billion dollars over budget later, the campaign grinds on, vaccinating millions of children and hoping that each new year might see an end to the disease. But success remains elusive, against a surprisingly resilient virus, an unexpectedly weak vaccine and the vagaries of global politics, meeting with indifference from governments and populations alike. How did an innocuous campaign to rid the world of a crippling disease become a hostage of geopolitics? Why do parents refuse to vaccinate their children against polio? And why have poorly paid door-to-door healthworkers been assassinated? Thomas Abraham reports on the ground in search of answers.

The Creationists

Ronald L. Numbers
The Creationists Book PDF

Author : Ronald L. Numbers
Publisher : Harvard University Press
Page : 636 pages
File Size : 53,7 Mb
Release : 2006
Category : History
ISBN : 0674023390

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The Creationists by Ronald L. Numbers Pdf

In light of the embattled status of evolutionary theory, particularly as 'intelligent design' makes headway against Darwinism in the schools and in the courts, this account of the roots of creationism assumes new relevance. This edition offers an overview of the arguments and figures at the heart of the debate.

The Vaccine Race

Meredith Wadman
The Vaccine Race Book PDF

Author : Meredith Wadman
Publisher : Penguin
Page : 464 pages
File Size : 42,8 Mb
Release : 2017-02-07
Category : Science
ISBN : 9780698177789

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The Vaccine Race by Meredith Wadman Pdf

"A real jewel of science history...brims with suspense and now-forgotten catastrophe and intrigue...Wadman’s smooth prose calmly spins a surpassingly complicated story into a real tour de force."—The New York Times “Riveting . . . [The Vaccine Race] invites comparison with Rebecca Skloot's 2007 The Immortal Life of Henrietta Lacks.”—Nature The epic and controversial story of a major breakthrough in cell biology that led to the conquest of rubella and other devastating diseases. Until the late 1960s, tens of thousands of American children suffered crippling birth defects if their mothers had been exposed to rubella, popularly known as German measles, while pregnant; there was no vaccine and little understanding of how the disease devastated fetuses. In June 1962, a young biologist in Philadelphia, using tissue extracted from an aborted fetus from Sweden, produced safe, clean cells that allowed the creation of vaccines against rubella and other common childhood diseases. Two years later, in the midst of a devastating German measles epidemic, his colleague developed the vaccine that would one day wipe out homegrown rubella. The rubella vaccine and others made with those fetal cells have protected more than 150 million people in the United States, the vast majority of them preschoolers. The new cells and the method of making them also led to vaccines that have protected billions of people around the world from polio, rabies, chicken pox, measles, hepatitis A, shingles and adenovirus. Meredith Wadman’s masterful account recovers not only the science of this urgent race, but also the political roadblocks that nearly stopped the scientists. She describes the terrible dilemmas of pregnant women exposed to German measles and recounts testing on infants, prisoners, orphans, and the intellectually disabled, which was common in the era. These events take place at the dawn of the battle over using human fetal tissue in research, during the arrival of big commerce in campus labs, and as huge changes take place in the laws and practices governing who “owns” research cells and the profits made from biological inventions. It is also the story of yet one more unrecognized woman whose cells have been used to save countless lives. With another frightening virus--measles--on the rise today, no medical story could have more human drama, impact, or urgency than The Vaccine Race.

Jonas Salk

Charlotte DeCroes Jacobs,Charlotte Jacobs
Jonas Salk Book PDF

Author : Charlotte DeCroes Jacobs,Charlotte Jacobs
Publisher : Oxford University Press, USA
Page : 588 pages
File Size : 54,9 Mb
Release : 2015
Category : Biography & Autobiography
ISBN : 9780199334414

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Jonas Salk by Charlotte DeCroes Jacobs,Charlotte Jacobs Pdf

"He first full biography of Jonas Salk offers a complete picture of the enigmatic figure, from his early years working on an influenza vaccine--for which he never fully got credit--to his seminal creation of the Polio vaccine, up through his later work to find a cure for AIDS"--

The Troop

Nick Cutter
The Troop Book PDF

Author : Nick Cutter
Publisher : Simon and Schuster
Page : 464 pages
File Size : 50,8 Mb
Release : 2014-02-25
Category : Fiction
ISBN : 9781476717753

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The Troop by Nick Cutter Pdf

WINNER OF THE JAMES HERBERT AWARD FOR HORROR WRITING “The Troop scared the hell out of me, and I couldn’t put it down. This is old-school horror at its best.” —Stephen King Once every year, Scoutmaster Tim Riggs leads a troop of boys into the Canadian wilderness for a weekend camping trip—a tradition as comforting and reliable as a good ghost story around a roaring bonfire. But when an unexpected intruder stumbles upon their campsite—shockingly thin, disturbingly pale, and voraciously hungry—Tim and the boys are exposed to something far more frightening than any tale of terror. The human carrier of a bioengineered nightmare. A horror that spreads faster than fear. A harrowing struggle for survival with no escape from the elements, the infected…or one another. Part Lord of the Flies, part 28 Days Later—and all-consuming—this tightly written, edge-of-your-seat thriller takes you deep into the heart of darkness, where fear feeds on sanity…and terror hungers for more.

Between Hope and Fear

Michael Kinch
Between Hope and Fear Book PDF

Author : Michael Kinch
Publisher : Simon and Schuster
Page : 360 pages
File Size : 45,7 Mb
Release : 2018-07-03
Category : Science
ISBN : 9781681778204

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Between Hope and Fear by Michael Kinch Pdf

If you have a child in school, you may have heard stories of long-dormant diseases suddenly reappearing—cases of measles, mumps, rubella, and whooping cough cropping up everywhere from elementary schools to Ivy League universities because a select group of parents refuse to vaccinate their children. Between Hope and Fear tells the remarkable story of vaccine-preventable infectious diseases and their social and political implications. While detailing the history of vaccine invention, Kinch reveals the ominous reality that our victories against vaccine-preventable diseases are not permanent—and could easily be undone. In the tradition of John Barry’s The Great Influenza and Siddhartha Mukherjee’s The Emperor of All Maladies, Between Hope and Fear relates the remarkable intersection of science, technology, and disease that has helped eradicate many of the deadliest plagues known to man.

Cutting for Stone

Abraham Verghese
Cutting for Stone Book PDF

Author : Abraham Verghese
Publisher : Random House India
Page : 391 pages
File Size : 43,7 Mb
Release : 2012-05-17
Category : Fiction
ISBN : 9788184001754

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Cutting for Stone by Abraham Verghese Pdf

Marion and Shiva Stone are twin brothers born of a secret union between a beautiful Indian nun and a brash British surgeon. Orphaned by their mother’s death and their father’s disappearance and bound together by a preternatural connection and a shared fascination with medicine, the twins come of age as Ethiopia hovers on the brink of revolution. Moving from Addis Ababa to New York City and back again, Cutting for Stone is an unforgettable story of love and betrayal, medicine and ordinary miracles—and two brothers whose fates are forever intertwined.

Salt in My Soul

Mallory Smith
Salt in My Soul Book PDF

Author : Mallory Smith
Publisher : Random House
Page : 336 pages
File Size : 55,9 Mb
Release : 2019-03-12
Category : Biography & Autobiography
ISBN : 9781984855435

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Salt in My Soul by Mallory Smith Pdf

The diaries of a remarkable young woman who was determined to live a meaningful and happy life despite her struggle with cystic fibrosis and a rare superbug—from age fifteen to her death at the age of twenty-five—the inspiration for the original streaming documentary Salt in My Soul “An exquisitely nuanced chronicle of a terrified but hopeful young woman whose life was beginning and ending, all at once.”—Los Angeles Times Diagnosed with cystic fibrosis at the age of three, Mallory Smith grew up to be a determined, talented young woman who inspired others even as she privately raged against her illness. Despite the daily challenges of endless medical treatments and a deep understanding that she’d never lead a normal life, Mallory was determined to “Live Happy,” a mantra she followed until her death. Mallory worked hard to make the most out of the limited time she had, graduating Phi Beta Kappa from Stanford University, becoming a cystic fibrosis advocate well known in the CF community, and embarking on a career as a professional writer. Along the way, she cultivated countless intimate friendships and ultimately found love. For more than ten years, Mallory recorded her thoughts and observations about struggles and feelings too personal to share during her life, leaving instructions for her mother to publish her work posthumously. She hoped that her writing would offer insight to those living with, or loving someone with, chronic illness. What emerges is a powerful and inspiring portrait of a brave young woman and blossoming writer who did not allow herself to be defined by disease. Her words offer comfort and hope to readers, even as she herself was facing death. Salt in My Soul is a beautifully crafted, intimate, and poignant tribute to a short life well lived—and a call for all of us to embrace our own lives as fully as possible.

Vaccines & Your Child

Paul A. Offit,Charlotte A. Moser
Vaccines Your Child Book PDF

Author : Paul A. Offit,Charlotte A. Moser
Publisher : Columbia University Press
Page : 259 pages
File Size : 47,6 Mb
Release : 2011
Category : Health & Fitness
ISBN : 9780231153072

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Vaccines & Your Child by Paul A. Offit,Charlotte A. Moser Pdf

Two leading advocates for modern vaccines answer parents' numerous questions about the underlying science of modern vaccines and the value of childhood immunization, while addressing parents' concerns about vaccine safety.