The Cytochemical Bioassay Of Polypeptide Hormones

Author : J. Chayen
Publisher : Springer Science & Business Media
Page : 336 pages
File Size : 50,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642814594

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The Cytochemical Bioassay of Polypeptide Hormones by J. Chayen Pdf

The cytochemical bioassay system was described in a short abstract in 1971, and more fully, in the cytochemical bioassay of corticotrophin, in 1972. Since then, cytochemical bioassays have been described for several polypeptide hormones, and these assays are already widely used. It is expedient that the subject should be reviewed, as it is in this monograph, by one writer who has had the good fortune to have taken part in the growth of cytochemistry from its early origins to its present position as the basis of possibly the most sensitive bioassay system currently available. However, it should be noted that major contributions have been made by many, both to the development of the subject and to the establishment of the bioassays. The object of this preface is to try to give some perspective to the growth of this subject and to record that the cytochemical bioassay system has been fostered by many outstanding scientists in an atmosphere of remarkable goodwill. To begin with, there could have been no cytochemical bioassays until cytochem istry had been converted from its rather unsure origins into a precise and quantitative form of cellular biochemistry. This was done with skill and enthusiastic dedication by my colleagues, Dr. Lucille Bitensky, Dr. F. P. Altman, Dr. R. G. L. W. Poulter and Mr. A. A. Silcox, first at the Royal College of Butcher, Dr.

Author : J Chayen,Lucille Bitensky
Publisher : Butterworth-Heinemann
Page : 439 pages
File Size : 53,9 Mb
Release : 2013-10-22
Category : Medical
ISBN : 9781483165400

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Cytochemical Bioassays by J Chayen,Lucille Bitensky Pdf

Cytochemical Bioassays: Techniques and Clinical Applications describes the techniques and clinical applications of cytochemical bioassays, particularly with respect to polypeptide hormones. This book discusses the clinical and research implications of studies that use these techniques. This text is comprised of 14 chapters; the first of which introduces the reader to the origins and general principles of cytochemical bioassays, along with their advantages. This discussion is followed by a chapter that explains what is meant by ""an assay""; for what purpose assays are done; the basic components of an assay method; and the nature of the difference between in vivo and in vitro hormone bioassays, in vitro ligand assays, and enzyme assays. Attention then turns to the techniques of cytochemical bioassays and the cytochemical bioassay procedures for adrenocorticotropic hormones; thyroid-stimulating hormones; the thyroid-stimulating antibody of Graves' disease; thyroid growth stimulating and blocking immunoglobulins; and luteinizing hormones. The next chapters focus on the technique and clinical relevance of a cytochemical bioassay for gastrin-like activity and for measurement of antidiuretic hormones, parathyroid hormones, angiotensin II, natriuretic hormones, and hypothalamic regulating hormones. This book will be of interest to clinicians and practitioners of biology, biochemistry, and endocrinology.

Author : Hans Lyon
Publisher : Springer Science & Business Media
Page : 582 pages
File Size : 45,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642737428

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Theory and Strategy in Histochemistry by Hans Lyon Pdf

If you want practical information on how to use this book please refer to "Note to the Readers" p. VII. Histochemistry and cytochemistry are essential tools in biomedical research and routine service laboratories. Most texts on histochemistry fall into one of two categories: 1. Encyclopaedic texts covering all or nearly all information available on the whole or selected parts of histochemistry. 2. Reviews or surveys of methods found to be useful by the author(s). While the former category often appeals to the more philosophically inclined reader, direct guidance on the selection of technique may be difficult to find. In contrast, the latter category are often excellent sources for details on how to perform a particular method with a reasonable chance of success. Consideration of the exact mechanism of staining, of possible reasons for failure, and of alternative techniques are, however, frequently lacking. This book is an introduction to the scientific basis of histochemistry and is intended to provide a background for the selection and development of appro priate methods. It is not a "cook book" and readers expecting exhaustive methodological descriptions will be disappointed. Although most ofthe contributors to this book would not describe themselves as histochemists, they have all at some time found it essential to develop a basic understanding of histochemistry. This book contains the information they would have greatly appreciated ready access to at that time.

Author : Anonim
Publisher : Unknown
Page : 1818 pages
File Size : 43,5 Mb
Release : 1976
Category : Medicine
ISBN : OSU:32436000861995

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Bibliography of Medical Reviews by Anonim Pdf

Author : National Library of Medicine (U.S.)
Publisher : Unknown
Page : 1456 pages
File Size : 44,6 Mb
Release : 1983
Category : Medicine
ISBN : MINN:31951D00170007S

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National Library of Medicine Current Catalog by National Library of Medicine (U.S.) Pdf

Author : Anonim
Publisher : Unknown
Page : 1476 pages
File Size : 41,9 Mb
Release : 1991
Category : Medicine
ISBN : OSU:32436010178778

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Cumulated Index Medicus by Anonim Pdf

Author : V.C. Medvei
Publisher : Springer Science & Business Media
Page : 912 pages
File Size : 43,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789400973046

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A History of Endocrinology by V.C. Medvei Pdf

o history of endocrinology can be written without reference N to Sir Humphry Davy Rolleston, whose monumental study of the subject appeared in 1936 under the modest subtitle: The Endocrine Organs in Health and Disease with an Historical Review. It was based on the author's Fitzpatrick Lectures at the Royal College of Physicians of London in 1933 and 1934. The lectureship, which dates from 1901, is devoted to the History of Medicine. Rolleston's work as regards scholarship and delivery cannot be surpassed and will remain the solid basis for any further study. It is of interest to note that Rolleston gave the Fitzpatrick Lectures when he was 71 years of age and had his book published when he was 74. By that time he had achieved most of his professional aims and all the honours a distinguished medical career can offer (see Section II). He perceived clearly that endocrinology was "an enormous subject in a most active stage of growth", which "recently has received most valuable help from organic chemists, who have devoted much time to the elucidation of the structure, isolation and synthesis of the hormones". He remarked that the knowledge of endocrinology was expanding with extreme rapidity, and it has been suggested that in this respect it would appear to be itself influenced by a growth hormone. He continued: "Before 1890 there were comparatively few publications dealing with the ductless glands, but in 1913, A.

Author : Richard A. Donald
Publisher : Elsevier Health Sciences
Page : 808 pages
File Size : 50,8 Mb
Release : 1984-03-22
Category : Health & Fitness
ISBN : 9781483289434

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Endocrine Disorders by Richard A. Donald Pdf

Endocrine Disorders

Author : National Library of Medicine (U.S.)
Publisher : Unknown
Page : 1442 pages
File Size : 43,8 Mb
Release : 1983
Category : Medicine
ISBN : UOM:39015074107650

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Current Catalog by National Library of Medicine (U.S.) Pdf

First multi-year cumulation covers six years: 1965-70.

Author : R C Sheppard
Publisher : Royal Society of Chemistry
Page : 560 pages
File Size : 49,8 Mb
Release : 2007-10-31
Category : Science
ISBN : 9781847557353

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Amino Acids, Peptides and Proteins by R C Sheppard Pdf

Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 80 years the Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a 'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued. The current list of Specialist Periodical Reports can be seen on the inside flap of this volume.

Author : Brian Henderson
Publisher : Unknown
Page : 104 pages
File Size : 53,6 Mb
Release : 1983
Category : Connective tissues
ISBN : NWU:35558000702171

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The Application of Quantitative Cytochemistry to the Study of Diseases of the Connective Tissues by Brian Henderson Pdf

Author : Klaus Havemann,George D. Sorenson,Clauss Gropp
Publisher : Springer Science & Business Media
Page : 307 pages
File Size : 47,8 Mb
Release : 2013-03-09
Category : Medical
ISBN : 9783642825330

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Peptide Hormones in Lung Cancer by Klaus Havemann,George D. Sorenson,Clauss Gropp Pdf

The incidence of lung cancer has reached epidemic proportions throughout the civilized world. One indication of the dimensions of this problem is that in the United States lung cancer has become the leading cause of cancer death in women as well as men. In 1912 there was a "nearly complete consensus of opinion that primary malignant neoplasms of the lung (were one) of the rarest forms of disease," according to Adler. By 1937, however, it had become clear that the incidence of lung cancer was increasing significantly; this increase has been progressive ever since. It is now well known that some lung cancers give rise to a variety of hormones which, at times, produce clinical manifestations. The association of hormone production with a "nonendocrine" tumor raises many questions, the answers to which may shed some light on the etiology of this prevalent form of cancer. This fascinating prob lem has stimulated a wide variety of studies in both the clinical and the basic sciences. A number of the more recent studies in this field were discussed at the International Symposium on Peptide Hor mones and Lung Cancer held in Marburg, West Germany, on June 18-20, 1984. This volume contains the papers that were pre sented on this occasion.

Author : M. Wallis,S. L. Howell,Keith William Taylor
Publisher : John Wiley & Sons
Page : 512 pages
File Size : 53,9 Mb
Release : 1985
Category : Nature
ISBN : UOM:39015009572275

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The Biochemistry of the Polypeptide Hormones by M. Wallis,S. L. Howell,Keith William Taylor Pdf

The Biochemistry of Polypeptide Hormones is intended to meet the needs particularly of advanced undergraduates, preclinical students and postgraduates, and provide an introduction to the research literature. All the main groups of polypeptide hormones are covered, and special chapters deal with structure-function relationships, hormone receptors, the role of second messengers and the applications of recombinant DNA technology.

Author : A. Pinchera
Publisher : Springer Science & Business Media
Page : 579 pages
File Size : 44,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461309451

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Thyroid Autoimmunity by A. Pinchera Pdf

In 1956, three groups independently reported evidence that some thyroid disease appearing spontaneously in humans or experimentally induced in animals are related to autoimmune processes. The interval between these landmark discoveries and the present has witnessed a remarkable and continuing growth of both knowledge and concepts concerning the mechanisms of immune regulation, the pathogenesis of autoimmune thyroid diseases, and their clinical and laboratory manifestations. More importantly knowledge of thyroid autoimmunity has, in many respects, comprised the vanguard of an ever increasing appreciation and understanding of autoimmune diseases in general. On November 24-26 1986, an International Symposium on Thyroid Autoimmunity was held in Pisa. Its purpose was to commemorate the birth of thyroid autoimmunity as a scientific discipline, to summarize current knowledge and concepts in this area, and where possible, to anticipate areas of opportunity for the future - hence the theme of the Symposium, Memories and Perspectives. To open the meeting, the Magnifico Rettore (Chancellor) of the University of Pisa granted special Awards to Dr. Deborah Doniach, Dr. Ivan Roitt, and Dr. Noel R. Rose, who published the first fundamental studies in the field of thyroid autoimmunity, and to Dr. Duncan G. Adams, whose discovery of the long-acting thyroid stimulator (LATS) opened the door to our current understanding of the pathogenesis of Graves' disease. During the meeting thirty plenary lectures were presented.

Author : Kalmon D. Post
Publisher : Springer Science & Business Media
Page : 515 pages
File Size : 41,7 Mb
Release : 2013-11-11
Category : Medical
ISBN : 9781468436686

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The Pituitary Adenoma by Kalmon D. Post Pdf

The idea for this book developed as an outcome of a multidisciplinary sym posium entitled "Pituitary Adenoma Update" that was held at Tufts-New En gland Medical Center in April 1977. The purpose of that symposium was to put together our current knowledge of the cause of pituitary tumors and discuss the diagnostic evaluation and management that was now appropriate, in light of the rapid advances that had taken place so recently in this area. Those of our colleagues who had presented papers at the symposium, as well as a number of others, were invited to contribute to this volume, which should serve as a presentation of the "state of the art" on all aspects of pitu itary tumors. We felt that such a book would be of value to endocrinologists, neurosurgeons, neuroradiologists, and pathologists who are involved in the investigation or care of patients with pituitary disorders. For a number of reasons, a review of pituitary adenomas seems particu larly timely. Rapid advances have taken place coincidentally in the fields of neurosurgery, neuroendocrinology, neuroradiology, neuropathology, and neuropharmacology. Seven major developments in these areas have occurred independently and almost simultaneously that have virtually revolutionized our approach to pituitary adenomas.