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Author : Mingzhou Ding,Dennis Glanzman
Publisher : Oxford University Press, USA
Page : 393 pages
File Size : 48,5 Mb
Release : 2011
Category : Medical
ISBN : 9780195393798
Theoretical, experimental and clinical perspectives. Readership: Graduate students, postdocs and research scientists in Neuroscience.
Author : Mingzhou Ding, PhD,Dennis Glanzman,PhD
Publisher : Oxford University Press
Page : 128 pages
File Size : 46,7 Mb
Release : 2011-01-18
Category : Medical
ISBN : 9780199397464
It is a well-known fact of neurophysiology that neuronal responses to identically presented stimuli are extremely variable. This variability has in the past often been regarded as "noise." At the single neuron level, interspike interval (ISI) histograms constructed during either spontaneous or stimulus evoked activity reveal a Poisson type distribution. These observations have been taken as evidence that neurons are intrinsically "noisy" in their firing properties. In fact, the use of averaging techniques, like post-stimulus time histograms (PSTH) or event-related potentials (ERPs) have largely been justified based on the presence of what was believed to be noise in the neuronal responses. More recent attempts to measure the information content of single neuron spike trains have revealed that a surprising amount of information can be coded in spike trains even in the presence of trial-to-trial variability. Multiple single unit recording experiments have suggested that variability formerly attributed to noise in single cell recordings may instead simply reflect system-wide changes in cellular response properties. These observations raise the possibility that, at least at the level of neuronal coding, the variability seen in single neuron responses may not simply reflect an underlying noisy process. They further raise the very distinct possibility that noise may in fact contain real, meaningful information which is available for the nervous system in information processing. To understand how neurons work in concert to bring about coherent behavior and its breakdown in disease, neuroscientists now routinely record simultaneously from hundreds of different neurons and from different brain areas, and then attempt to evaluate the network activities by computing various interdependence measures, including cross correlation, phase synchronization and spectral coherence. This book examines neuronal variability from theoretical, experimental and clinical perspectives.
Author : Mikhail I. Rabinovich,Karl J. Friston,Pablo Varona
Publisher : MIT Press
Page : 371 pages
File Size : 40,5 Mb
Release : 2023-12-05
Category : Medical
ISBN : 9780262549905
Experimental and theoretical approaches to global brain dynamics that draw on the latest research in the field. The consideration of time or dynamics is fundamental for all aspects of mental activity—perception, cognition, and emotion—because the main feature of brain activity is the continuous change of the underlying brain states even in a constant environment. The application of nonlinear dynamics to the study of brain activity began to flourish in the 1990s when combined with empirical observations from modern morphological and physiological observations. This book offers perspectives on brain dynamics that draw on the latest advances in research in the field. It includes contributions from both theoreticians and experimentalists, offering an eclectic treatment of fundamental issues. Topics addressed range from experimental and computational approaches to transient brain dynamics to the free-energy principle as a global brain theory. The book concludes with a short but rigorous guide to modern nonlinear dynamics and their application to neural dynamics.
Author : Hyder Fahmeed
Publisher : Humana Press
Page : 0 pages
File Size : 50,9 Mb
Release : 2014-11-03
Category : Medical
ISBN : 1627038817
If a picture is worth a thousand words, then dynamic images of brain activity certainly warrant many, many more. This book will help users learn to decipher the dynamic imaging data that will be critical to our future understanding of complex brain functions. In recent years, there have been unprecedented methodological advancements in the imaging of brain activity. These techniques allow the measurement of everything from neural activity (e.g., membrane potential, ion ?ux, neurotransmitter ?ux) to energy metabolism (e.g., glucose consumption, oxygen consumption, creatine kinase ?ux) and functional hyperemia (e.g., blood ?ow, volume, oxygenation). This book deals with a variety of magnetic resonance, electrophysiology, and optical methods that are often used to measure some of these dynamic processes. All chapters were written by leading experts, spanning three continents, specializing in state-of-the-art methods. Brie?y, the book has ?ve sections. In the introductory section, there are two chapters; the ?rst one contains a brief pre- ble to dynamic brain imaging and the other presents a novel, analytical approach to processing of dynamically acquired data. The second section has four chapters and delves into a wide range of optical imaging methods. I am privileged to include a chapter from Lawrence B. Cohen, considered by many to be the authority on optical imaging and spectroscopy, both in vitro and in vivo [Cohen LB (1973) Physiol Rev.
Author : Christoph von der Malsburg,William A. Phillips,Wolf Singer
Publisher : MIT Press
Page : 367 pages
File Size : 40,9 Mb
Release : 2010
Category : Anatomy
ISBN : 9780262014717
"Nervous systems do not live by the rate code alone. The ceaseless activities of groups of neurons are choregraphed into waves, oscillations, synchronized rhythms, and transient coalitions; it is these that underlie behavior, memory, and conscious perception. This exuberant manifesto masterfully summarizes and reflects upon the relevant evidence of these patterns from all manner of brains, small and large." --
Author : J. A. Scott Kelso
Publisher : MIT Press
Page : 368 pages
File Size : 43,6 Mb
Release : 1995
Category : Behavior
ISBN : 0262611317
foreword by Hermann Haken For the past twenty years Scott Kelso's research has focused on extending the physical concepts of self- organization and the mathematical tools of nonlinear dynamics to understand how human beings (and human brains) perceive, intend, learn, control, and coordinate complex behaviors. In this book Kelso proposes a new, general framework within which to connect brain, mind, and behavior.Kelso's prescription for mental life breaks dramatically with the classical computational approach that is still the operative framework for many newer psychological and neurophysiological studies. His core thesis is that the creation and evolution of patterned behavior at all levels--from neurons to mind--is governed by the generic processes of self-organization. Both human brain and behavior are shown to exhibit features of pattern-forming dynamical systems, including multistability, abrupt phase transitions, crises, and intermittency. Dynamic Patterns brings together different aspects of this approach to the study of human behavior, using simple experimental examples and illustrations to convey essential concepts, strategies, and methods, with a minimum of mathematics. Kelso begins with a general account of dynamic pattern formation. He then takes up behavior, focusing initially on identifying pattern-forming instabilities in human sensorimotor coordination. Moving back and forth between theory and experiment, he establishes the notion that the same pattern-forming mechanisms apply regardless of the component parts involved (parts of the body, parts of the nervous system, parts of society) and the medium through which the parts are coupled. Finally, employing the latest techniques to observe spatiotemporal patterns of brain activity, Kelso shows that the human brain is fundamentally a pattern forming dynamical system, poised on the brink of instability. Self-organization thus underlies the cooperative action of neurons that produces human behavior in all its forms.
Author : Hermann Haken
Publisher : Springer Science & Business Media
Page : 333 pages
File Size : 52,5 Mb
Release : 2007-12-22
Category : Science
ISBN : 9783540752387
This is an excellent introduction for graduate students and nonspecialists to the field of mathematical and computational neurosciences. The book approaches the subject via pulsed-coupled neural networks, which have at their core the lighthouse and integrate-and-fire models. These allow for highly flexible modeling of realistic synaptic activity, synchronization and spatio-temporal pattern formation. The more advanced pulse-averaged equations are discussed.
Author : György Buzsáki,Yves Christen
Publisher : Springer
Page : 181 pages
File Size : 49,6 Mb
Release : 2016-05-02
Category : Medical
ISBN : 9783319288024
This book brings together leading investigators who represent various aspects of brain dynamics with the goal of presenting state-of-the-art current progress and address future developments. The individual chapters cover several fascinating facets of contemporary neuroscience from elementary computation of neurons, mesoscopic network oscillations, internally generated assembly sequences in the service of cognition, large-scale neuronal interactions within and across systems, the impact of sleep on cognition, memory, motor-sensory integration, spatial navigation, large-scale computation and consciousness. Each of these topics require appropriate levels of analyses with sufficiently high temporal and spatial resolution of neuronal activity in both local and global networks, supplemented by models and theories to explain how different levels of brain dynamics interact with each other and how the failure of such interactions results in neurologic and mental disease. While such complex questions cannot be answered exhaustively by a dozen or so chapters, this volume offers a nice synthesis of current thinking and work-in-progress on micro-, meso- and macro- dynamics of the brain.
Author : Erol Basar
Publisher : CRC Press
Page : 432 pages
File Size : 42,6 Mb
Release : 2004-06-23
Category : Medical
ISBN : 9781134394838
Memory itself is inseparable from all other brain functions and involves distributed dynamic neural processes. A wealth of publications in neuroscience literature report that the concerted action of distributed multiple oscillatory processes (EEG oscillations) play a major role in brain functioning. The analysis of function-related brain oscillatio
Author : Maria Marinaro,Silvia Scarpetta,Yoko Yamaguchi
Publisher : Springer Science & Business Media
Page : 149 pages
File Size : 46,8 Mb
Release : 2008-10-23
Category : Computers
ISBN : 9783540888529
This book is devoted to graduate students and researchers with different scientific background (including physics, mathematics, biology, neuroscience, etc.) who wish to learn brain science beyond the boundary of their fields. The volume presents 12 thoroughly revised tutorial papers based on lectures given by leading researchers at the 12th International Summer School on Neural Networks in Erice, Italy, in December 2007. The 12 invited and contributed papers presented provide primarily high-level tutorial coverage of the fields related to neuraldynamics, reporting recent experimental and theoretical results investigating the role of collective dynamics in hippocampal and parahippocampal regions and in the mammalian olfactory system. The book is divided into topical sections on hippocampus and neural oscillations, dynamics in olfactory system and behaviour, correlation structure of spiking trains, and neural network theories on associative memory.
Author : Georg Northoff
Publisher : John Benjamins Publishing
Page : 441 pages
File Size : 49,9 Mb
Release : 2004-01-23
Category : Psychology
ISBN : 9789027295873
"What is the mind?" "What is the relationship between brain and mind?" These are common questions. But "What is the brain?" is a rare question in both the neurosciences and philosophy. The reason for this may lie in the brain itself: Is there a "brain problem"? In this fresh and innovative book, Georg Northoff demonstrates that there is in fact a "brain problem". He argues that our brain can only be understood when its empirical functions are directly related to the modes of acquiring knowledge, our epistemic abilities and inabilities. Drawing on the latest neuroscientific data and philosophical theories, he provides an empirical-epistemic definition of the brain. Northoff reveals the basic conceptual confusion about the relationship between mind and brain that has so obstinately been lingering in both neuroscience and philosophy. He subsequently develops an alternative framework where the integration of the brain within body and environment is central. This novel approach plunges the reader into the depths of our own brain. The "Philosophy of the Brain" that emerges opens the door to a fascinating world of new findings that explore the mind and its relationship to our very human brain. (Series A)
Author : Erol Basar
Publisher : CRC Press
Page : 287 pages
File Size : 41,6 Mb
Release : 2004-06-23
Category : Medical
ISBN : 9780203298732
Memory itself is inseparable from all other brain functions and involves distributed dynamic neural processes. A wealth of publications in neuroscience literature report that the concerted action of distributed multiple oscillatory processes (EEG oscillations) play a major role in brain functioning. The analysis of function-related brain oscillatio
Author : Erol Başar,Theodore H. Bullock
Publisher : Springer Science & Business Media
Page : 554 pages
File Size : 45,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642745577
This volume is based on contributions to the second Brain Dynamics Conference, held in Berlin on August 10-14, 1987, as a satellite conference of the Budapest Congress of the International Brain Research Organization. Like the volume resulting from the first conference, Dynamics of Sensory and Cognitive Processing by the Brain, the present work covers new approaches to brain function, with emphasis on electromagnetic fields, EEG, event-related potentials, connectivistic views, and neural networks. Close attention is also paid to research in the emerging field of deterministic chaos and strange attractors. The diversity of this collection of papers reflects a multipronged advance in a hitherto relatively neglected domain, i. e., the study of signs of dynamic processes in organized neural tissue in order both to explain them and to exploit them for clues to system function. The need is greater than ever for new windows. This volume reflects a historical moment, the moment when a relatively neglected field of basic research into available signs of dynamic processes ongoing in organized neural tissue is expanding almost explosively to complement other approaches. From the topics treated, this book should appeal, as did its predecessor, to neuroscientists, neurologists, scientists studying complex systems, artificial intelligence, and neural networks, psychobiologists, and all basic and clinical investigators concerned with new techniques of monitoring and analyzing the brain's electromagnetic activity.
Author : Henry Kennedy,David C. Van Essen,Yves Christen
Publisher : Springer
Page : 173 pages
File Size : 54,6 Mb
Release : 2016-03-10
Category : Medical
ISBN : 9783319277776
This book has brought together leading investigators who work in the new arena of brain connectomics. This includes ‘macro-connectome’ efforts to comprehensively chart long-distance pathways and functional networks; ‘micro-connectome’ efforts to identify every neuron, axon, dendrite, synapse, and glial process within restricted brain regions; and ‘meso-connectome’ efforts to systematically map both local and long-distance connections using anatomical tracers. This book highlights cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions that are vital for brain function. The power of connectomic approaches in characterizing abnormal circuits in the many brain disorders that afflict humankind is considered. Experts in computational neuroscience and network theory provide perspectives needed for synthesizing across different scales in space and time. Altogether, this book provides an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.
Author : Theodore Melnechuk,Erol Başar
Publisher : Springer Science & Business Media
Page : 408 pages
File Size : 46,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642715310
In neurophysiology, the emphasis has been on single-unit studies for a quarter century, since the sensory work by Lettwin and coworkers and by Hubel and Wiesel, the cen tral work by Mountcastle, the motor work by the late Evarts, and so on. In recent years, however, field potentials - and a more global approach general ly - have been receiving renewed and increasing attention. This is a result of new findings made possible by technical and conceptual advances and by the confirma tion and augmentation of earlier findings that were widely ignored for being contro versial or inexplicable. To survey the state of this active field, a conference was held in West Berlin in August 1985 that attempted to cover all of the new approaches to the study of brain function. The approaches and emphases were very varied: basic and applied, electric and magnetic, EEG and EP/ERP, connectionistic and field, global and local fields, surface and multielectrode, low frequencies and high frequencies, linear and non linear. The conference comprised sessions of invited lectures, a panel session of seven speakers on "How brains may work," and a concluding survey of relevant methodologies. The conference showed that the combination of concepts, methods, and results could open up new important vistas in brain research. Included here are the proceedings of the conference, updated and revised by the authors. Several attendees who did not present papers at the conference later ac cepted my invitation to write chapters for the book.